OLFM4 (olfactomedin 4) - Rat Genome Database

Name: OLFM4
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: OLFM4 (olfactomedin 4) Homo sapiens

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Symbol:

OLFM4

Name:

olfactomedin 4

RGD ID:

1323306

HGNC Page

HGNC:17190

Description:

Enables cadherin binding activity and structural molecule activity. Involved in positive regulation of substrate adhesion-dependent cell spreading. Located in several cellular components, including intercellular bridge; perinuclear region of cytoplasm; and specific granule. Part of protein-containing complex.

Type:

protein-coding

RefSeq Status:

REVIEWED

Previously known as:

antiapoptotic protein GW112; bA209J19.1; G-CSF-stimulated clone 1 protein; GC1; GW112; hGC-1; hOLfD; KIAA4294; olfactoimedin; olfactomedin-4; OlfD; OLM4; pDP4; tiarin; UNQ362

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Mus musculus (house mouse):	Olfm4 (olfactomedin 4)	HGNC	Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Rattus norvegicus (Norway rat):	Olfm4 (olfactomedin 4)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther
Chinchilla lanigera (long-tailed chinchilla):	Olfm4 (olfactomedin 4)	NCBI	Ortholog
Pan paniscus (bonobo/pygmy chimpanzee):	OLFM4 (olfactomedin 4)	NCBI	Ortholog
Canis lupus familiaris (dog):	OLFM4 (olfactomedin 4)	HGNC	HomoloGene, NCBI
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Olfm4 (olfactomedin 4)	NCBI	Ortholog
Sus scrofa (pig):	OLFM4 (olfactomedin 4)	HGNC	EggNOG, Ensembl, NCBI, OMA, OrthoDB, Panther, Treefam
Chlorocebus sabaeus (green monkey):	OLFM4 (olfactomedin 4)	NCBI	Ortholog
Heterocephalus glaber (naked mole-rat):	Olfm4 (olfactomedin 4)	NCBI	Ortholog
Other homologs ²
Rattus norvegicus (Norway rat):	Slc35a4 (solute carrier family 35, member A4)	HGNC	OMA
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Olfm4 (olfactomedin 4)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Olfm4 (olfactomedin 4)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	si:ch211-173a9.7	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid\|ZFIN)
Danio rerio (zebrafish):	olfm4.2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid\|ZFIN)
Xenopus tropicalis (tropical clawed frog):	olfm4	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus laevis (African clawed frog):	olfm4.L	Alliance	DIOPT (Xenbase)

Allele / Splice:

See ClinVar data

Latest Assembly:

GRCh38 - Human Genome Assembly GRCh38

Position:

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	13	53,028,813 - 53,052,057 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	13	53,028,813 - 53,052,057 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	13	53,602,948 - 53,626,192 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	13	52,500,973 - 52,524,193 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	13	52,500,972 - 52,524,187	NCBI
Celera	13	34,589,022 - 34,612,243 (+)	NCBI		Celera
Cytogenetic Map	13	q14.3	NCBI
HuRef	13	34,317,261 - 34,340,581 (+)	NCBI		HuRef
CHM1_1	13	53,570,960 - 53,594,281 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	13	52,244,407 - 52,267,681 (+)	NCBI		T2T-CHM13v2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

chromosome 13q14 deletion syndrome (IAGP)

endometriosis (EXP)

intellectual disability (IAGP)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(S)-nicotine (EXP)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (EXP,ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,4-dibromophenyl 2,4,5-tribromophenyl ether (ISO)

4,4'-sulfonyldiphenol (ISO)

5-fluorouracil (ISO)

5-iodotubercidin (EXP)

afimoxifene (EXP)

all-trans-retinoic acid (EXP)

benzo[a]pyrene (EXP)

bisphenol A (ISO)

bisphenol F (ISO)

cadmium atom (EXP)

cadmium dichloride (EXP)

CGP 52608 (EXP)

chlordecone (ISO)

cobalt atom (EXP)

copper atom (ISO)

copper(0) (ISO)

dexamethasone (EXP)

ICI-164384 (EXP)

nickel atom (EXP)

nicotine (EXP)

ozone (ISO)

paraquat (ISO)

silicon dioxide (ISO)

sodium dichromate (ISO)

sulforaphane (EXP)

Tungsten carbide (EXP)

valproic acid (EXP)

zoledronic acid (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell adhesion (IEA)

immune response (ISO)

negative regulation of canonical NF-kappaB signal transduction (ISO)

negative regulation of immune response (ISO)

positive regulation of substrate adhesion-dependent cell spreading (IDA)

signal transduction (IBA)

Cellular Component

azurophil granule (IDA)

cytosol (IDA)

extracellular exosome (HDA)

extracellular region (IEA,TAS)

extracellular space (HDA,IBA,IDA,IMP)

intercellular bridge (IDA)

mitochondrion (IEA)

nucleoplasm (IDA)

perinuclear region of cytoplasm (IDA)

plasma membrane (IDA)

protein-containing complex (IMP)

secretory granule (IDA)

specific granule (IDA)

specific granule lumen (TAS)

tertiary granule lumen (TAS)

Molecular Function

cadherin binding (IMP)

protein binding (IPI)

structural molecule activity (IDA)

Phenotype Annotations Click to see Annotation Detail View

Human Phenotype

Intellectual disability (IAGP)

References

References - curated

#	Reference Title	Reference Citation
1.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:2824652	PMID:11302958	PMID:11867215	PMID:12477932	PMID:12975309	PMID:16344560	PMID:16502470	PMID:16566923	PMID:17650212	PMID:18281536	PMID:18798264	PMID:19056867
PMID:19199708	PMID:19450592	PMID:19670418	PMID:20534456	PMID:20724538	PMID:20878207	PMID:21048224	PMID:21067260	PMID:21270618	PMID:21415212	PMID:21470957	PMID:21832049
PMID:21873635	PMID:21904905	PMID:21986994	PMID:22011044	PMID:22187488	PMID:22398066	PMID:22471589	PMID:22484627	PMID:22658931	PMID:22844115	PMID:23251661	PMID:23376485
PMID:23533145	PMID:23563607	PMID:23570326	PMID:23922742	PMID:24070418	PMID:24495253	PMID:24529757	PMID:24861553	PMID:25333937	PMID:25400027	PMID:25416956	PMID:25771901
PMID:26011333	PMID:26070873	PMID:26162090	PMID:26186194	PMID:26303970	PMID:26398045	PMID:26416558	PMID:26581960	PMID:26871282	PMID:26973250	PMID:27635771	PMID:27939521
PMID:28012926	PMID:28320108	PMID:28514442	PMID:28669815	PMID:29488661	PMID:30137688	PMID:30764901	PMID:31241767	PMID:31318138	PMID:31432153	PMID:31515488	PMID:31923206
PMID:31990698	PMID:32276789	PMID:32296183	PMID:32457219	PMID:33253592	PMID:33318499	PMID:33355521	PMID:33570127	PMID:33622275	PMID:33711267	PMID:33961781	PMID:34496567
PMID:34906535	PMID:34912753	PMID:35156780	PMID:35337817	PMID:35410162	PMID:35487976	PMID:35806447	PMID:36349502	PMID:36549285	PMID:36577836	PMID:36949045	PMID:37280213
PMID:38613883

Genomics

Comparative Map Data

OLFM4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	13	53,028,813 - 53,052,057 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	13	53,028,813 - 53,052,057 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	13	53,602,948 - 53,626,192 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	13	52,500,973 - 52,524,193 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	13	52,500,972 - 52,524,187	NCBI
Celera	13	34,589,022 - 34,612,243 (+)	NCBI		Celera
Cytogenetic Map	13	q14.3	NCBI
HuRef	13	34,317,261 - 34,340,581 (+)	NCBI		HuRef
CHM1_1	13	53,570,960 - 53,594,281 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	13	52,244,407 - 52,267,681 (+)	NCBI		T2T-CHM13v2.0

Olfm4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	80,237,742 - 80,260,581 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	80,221,521 - 80,260,579 (+)	Ensembl		GRCm39 Ensembl
GRCm38	14	80,000,302 - 80,023,141 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	79,984,081 - 80,023,139 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	14	80,400,109 - 80,421,737 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	14	78,734,457 - 78,756,085 (+)	NCBI		MGSCv36	mm8
Celera	14	77,496,092 - 77,517,728 (+)	NCBI		Celera
Cytogenetic Map	14	D3	NCBI
cM Map	14	42.78	NCBI

Olfm4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	15	61,790,889 - 61,838,773 (+)	NCBI		GRCr8
mRatBN7.2	15	55,385,100 - 55,429,687 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	55,407,148 - 55,429,681 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	15	59,532,623 - 59,555,138 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	15	60,650,998 - 60,673,516 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	15	57,475,894 - 57,498,416 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	15	62,384,263 - 62,429,450 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	62,406,873 - 62,429,449 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	15	66,064,452 - 66,086,655 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	15	61,267,802 - 61,290,288 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	15	61,222,799 - 61,304,901 (+)	NCBI
Celera	15	54,981,171 - 55,003,416 (+)	NCBI		Celera
Cytogenetic Map	15	q12	NCBI

Olfm4
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955404	50,549,151 - 50,570,305 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955404	50,549,218 - 50,570,302 (-)	NCBI	ChiLan1.0	ChiLan1.0

OLFM4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	14	54,369,604 - 54,393,154 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	13	53,017,773 - 53,041,321 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	13	34,066,155 - 34,089,468 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	13	52,873,289 - 52,896,616 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	13	52,873,289 - 52,896,827 (+)	Ensembl	panpan1.1		panPan2

OLFM4
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	22	10,053,494 - 10,075,759 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	22	9,944,025 - 10,074,722 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	22	10,049,679 - 10,071,946 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	22	10,278,301 - 10,300,554 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	22	10,278,100 - 10,299,477 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	22	9,975,280 - 9,997,549 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	22	10,025,509 - 10,047,757 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	22	10,039,441 - 10,061,690 (+)	NCBI		UU_Cfam_GSD_1.0

Olfm4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	150,976,186 - 150,997,332 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936667	907,473 - 922,291 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936667	905,556 - 923,105 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

OLFM4
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	11	26,350,203 - 26,375,716 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	11	26,252,948 - 26,375,531 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	11	27,026,373 - 27,051,872 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

OLFM4
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	3	30,753,677 - 30,810,980 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	3	30,787,999 - 30,810,980 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666057	13,002,697 - 13,025,716 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Olfm4
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624748	14,494,619 - 14,516,015 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624748	14,394,961 - 14,515,850 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in OLFM4
24 total Variants

Clinical Variants

Name	Type	Condition(s)	Position(s)	Clinical significance
GRCh37/hg19 13q11-34(chr13:19053605-115108528)x3	copy number gain	See cases [RCV001353184]	Chr13:19053605..115108528 [GRCh37] Chr13:13q11-34	pathogenic
GRCh38/hg38 13q12.3-31.3(chr13:31363472-90575292)x3	copy number gain	See cases [RCV000050293]	Chr13:31363472..90575292 [GRCh38] Chr13:31937609..91227546 [GRCh37] Chr13:30835609..90025547 [NCBI36] Chr13:13q12.3-31.3	pathogenic
GRCh38/hg38 13q14.12-31.3(chr13:44967523-92738168)x1	copy number loss	See cases [RCV000050891]	Chr13:44967523..92738168 [GRCh38] Chr13:45541658..93390421 [GRCh37] Chr13:44439658..92188422 [NCBI36] Chr13:13q14.12-31.3	pathogenic
GRCh38/hg38 13q12.3-21.33(chr13:30697728-69471973)x1	copy number loss	See cases [RCV000051373]	Chr13:30697728..69471973 [GRCh38] Chr13:31271865..70046105 [GRCh37] Chr13:30169865..68944106 [NCBI36] Chr13:13q12.3-21.33	pathogenic
GRCh38/hg38 13q14.3(chr13:52598879-53101818)x3	copy number gain	Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052007]\|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052007]\|See cases [RCV000052007]	Chr13:52598879..53101818 [GRCh38] Chr13:53173014..53675953 [GRCh37] Chr13:52071015..52573954 [NCBI36] Chr13:13q14.3	uncertain significance
GRCh38/hg38 13q12.11-34(chr13:19837395-114327173)x3	copy number gain	See cases [RCV000053731]	Chr13:19837395..114327173 [GRCh38] Chr13:20411535..115085141 [GRCh37] Chr13:19309535..114110750 [NCBI36] Chr13:13q12.11-34	pathogenic
GRCh38/hg38 13q12.3-31.1(chr13:30318913-83610426)x3	copy number gain	See cases [RCV000053737]	Chr13:30318913..83610426 [GRCh38] Chr13:30893050..84184561 [GRCh37] Chr13:29791050..83082562 [NCBI36] Chr13:13q12.3-31.1	pathogenic
GRCh38/hg38 13q11-34(chr13:18565048-114327173)x3	copy number gain	See cases [RCV000053719]	Chr13:18565048..114327173 [GRCh38] Chr13:19139188..115085141 [GRCh37] Chr13:18037188..114110750 [NCBI36] Chr13:13q11-34	pathogenic
GRCh38/hg38 13q11-34(chr13:18850545-114327173)x3	copy number gain	See cases [RCV000053723]	Chr13:18850545..114327173 [GRCh38] Chr13:19296527..115085141 [GRCh37] Chr13:18194527..114110750 [NCBI36] Chr13:13q11-34	pathogenic
GRCh38/hg38 13q12.11-34(chr13:18946182-114304628)x3	copy number gain	See cases [RCV000053726]	Chr13:18946182..114304628 [GRCh38] Chr13:19520322..115070103 [GRCh37] Chr13:18418322..114088205 [NCBI36] Chr13:13q12.11-34	pathogenic
GRCh38/hg38 13q13.2-34(chr13:33528097-114327173)x3	copy number gain	See cases [RCV000053759]	Chr13:33528097..114327173 [GRCh38] Chr13:34102234..115085141 [GRCh37] Chr13:33000234..114110750 [NCBI36] Chr13:13q13.2-34	pathogenic
GRCh38/hg38 13q14.11-34(chr13:43219125-114327314)x3	copy number gain	See cases [RCV000053762]	Chr13:43219125..114327314 [GRCh38] Chr13:43793261..115085141 [GRCh37] Chr13:42691261..114110891 [NCBI36] Chr13:13q14.11-34	pathogenic
GRCh38/hg38 13q14.11-34(chr13:44164751-114327173)x3	copy number gain	See cases [RCV000053764]	Chr13:44164751..114327173 [GRCh38] Chr13:44738887..115085141 [GRCh37] Chr13:43636887..114110750 [NCBI36] Chr13:13q14.11-34	pathogenic
GRCh38/hg38 13q14.12-34(chr13:44733046-114327173)x3	copy number gain	See cases [RCV000053767]	Chr13:44733046..114327173 [GRCh38] Chr13:45307182..115085141 [GRCh37] Chr13:44205182..114110750 [NCBI36] Chr13:13q14.12-34	pathogenic
NM_006418.4(OLFM4):c.1121C>T (p.Ser374Leu)	single nucleotide variant	Malignant melanoma [RCV000062688]	Chr13:53050359 [GRCh38] Chr13:53624494 [GRCh37] Chr13:52522495 [NCBI36] Chr13:13q14.3	not provided
GRCh38/hg38 13q13.3-21.31(chr13:36777318-62955876)x1	copy number loss	See cases [RCV000133696]	Chr13:36777318..62955876 [GRCh38] Chr13:37351455..63530009 [GRCh37] Chr13:36249455..62428010 [NCBI36] Chr13:13q13.3-21.31	pathogenic
GRCh38/hg38 13q14.3(chr13:52381559-54493354)x3	copy number gain	See cases [RCV000134421]	Chr13:52381559..54493354 [GRCh38] Chr13:52955694..55067489 [GRCh37] Chr13:51853695..53965490 [NCBI36] Chr13:13q14.3	uncertain significance
GRCh38/hg38 13q14.11-31.1(chr13:41288493-85137552)x3	copy number gain	See cases [RCV000133944]	Chr13:41288493..85137552 [GRCh38] Chr13:41862629..85711687 [GRCh37] Chr13:40760629..84609688 [NCBI36] Chr13:13q14.11-31.1	pathogenic
GRCh38/hg38 13q12.11-34(chr13:19833130-114298614)x3	copy number gain	See cases [RCV000134104]	Chr13:19833130..114298614 [GRCh38] Chr13:20407270..115064089 [GRCh37] Chr13:19305270..114082191 [NCBI36] Chr13:13q12.11-34	pathogenic
GRCh38/hg38 13q12.3-21.32(chr13:31553608-65470367)x3	copy number gain	See cases [RCV000135808]	Chr13:31553608..65470367 [GRCh38] Chr13:32127745..66044499 [GRCh37] Chr13:31025745..64942500 [NCBI36] Chr13:13q12.3-21.32	pathogenic
GRCh38/hg38 13q11-34(chr13:18445862-114327173)x1	copy number loss	See cases [RCV000135610]	Chr13:18445862..114327173 [GRCh38] Chr13:19020001..115085141 [GRCh37] Chr13:10098739..114110750 [NCBI36] Chr13:13q11-34	pathogenic
GRCh38/hg38 13q14.11-31.1(chr13:41143820-85137552)x1	copy number loss	See cases [RCV000136526]	Chr13:41143820..85137552 [GRCh38] Chr13:41717956..85711687 [GRCh37] Chr13:40615956..84609688 [NCBI36] Chr13:13q14.11-31.1	pathogenic
GRCh38/hg38 13q14.2-31.1(chr13:47117587-84300935)x1	copy number loss	See cases [RCV000136647]	Chr13:47117587..84300935 [GRCh38] Chr13:47691722..84875070 [GRCh37] Chr13:46589723..83773071 [NCBI36] Chr13:13q14.2-31.1	pathogenic
GRCh38/hg38 13q14.11-34(chr13:40942298-114340331)x1	copy number loss	See cases [RCV000137893]	Chr13:40942298..114340331 [GRCh38] Chr13:41516434..115085141 [GRCh37] Chr13:40414434..114123908 [NCBI36] Chr13:13q14.11-34	pathogenic
GRCh38/hg38 13q13.1-31.1(chr13:32531486-86757044)x3	copy number gain	See cases [RCV000138339]	Chr13:32531486..86757044 [GRCh38] Chr13:33105623..87409299 [GRCh37] Chr13:32003623..86207300 [NCBI36] Chr13:13q13.1-31.1	pathogenic
GRCh38/hg38 13q12.11-34(chr13:19833130-114327106)x3	copy number gain	See cases [RCV000139078]	Chr13:19833130..114327106 [GRCh38] Chr13:20407270..115085141 [GRCh37] Chr13:19305270..114110683 [NCBI36] Chr13:13q12.11-34	pathogenic
GRCh38/hg38 13q11-34(chr13:18456040-114340285)x3	copy number gain	See cases [RCV000140004]	Chr13:18456040..114340285 [GRCh38] Chr13:19030180..115105760 [GRCh37] Chr13:17928180..114123862 [NCBI36] Chr13:13q11-34	pathogenic
GRCh38/hg38 13q13.3-21.32(chr13:37864226-67963788)x1	copy number loss	See cases [RCV000140744]	Chr13:37864226..67963788 [GRCh38] Chr13:38438363..68537920 [GRCh37] Chr13:37336363..67435921 [NCBI36] Chr13:13q13.3-21.32	pathogenic
GRCh38/hg38 13q14.2-21.31(chr13:47765202-62058520)x1	copy number loss	See cases [RCV000142223]	Chr13:47765202..62058520 [GRCh38] Chr13:48339337..62632653 [GRCh37] Chr13:47237338..61530654 [NCBI36] Chr13:13q14.2-21.31	pathogenic
GRCh38/hg38 13q12.11-34(chr13:19671934-114340331)x3	copy number gain	See cases [RCV000142924]	Chr13:19671934..114340331 [GRCh38] Chr13:20246074..115085141 [GRCh37] Chr13:19144074..114123908 [NCBI36] Chr13:13q12.11-34	pathogenic
GRCh38/hg38 13q11-34(chr13:18862146-114342258)x3	copy number gain	See cases [RCV000143462]	Chr13:18862146..114342258 [GRCh38] Chr13:19436286..115107733 [GRCh37] Chr13:18334286..114125835 [NCBI36] Chr13:13q11-34	pathogenic
GRCh38/hg38 13q12.3-31.3(chr13:31363472-90575292)x3	copy number gain	See cases [RCV000148244]	Chr13:31363472..90575292 [GRCh38] Chr13:31937609..91227546 [GRCh37] Chr13:30835609..90025547 [NCBI36] Chr13:13q12.3-31.3	pathogenic
GRCh38/hg38 13q12.11-34(chr13:19837395-114327173)x3	copy number gain	See cases [RCV000148126]	Chr13:19837395..114327173 [GRCh38] Chr13:20411535..115085141 [GRCh37] Chr13:19309535..114110750 [NCBI36] Chr13:13q12.11-34	pathogenic
GRCh37/hg19 13q12.11-34(chr13:19571503-115092569)x3	copy number gain	See cases [RCV000240150]	Chr13:19571503..115092569 [GRCh37] Chr13:13q12.11-34	pathogenic
GRCh37/hg19 13q14.3-21.1(chr13:52170957-57713087)x3	copy number gain	not provided [RCV001270648]	Chr13:52170957..57713087 [GRCh37] Chr13:13q14.3-21.1	uncertain significance
GRCh37/hg19 13q14.3-33.3(chr13:53551300-109850651)x1	copy number loss	See cases [RCV000449272]	Chr13:53551300..109850651 [GRCh37] Chr13:13q14.3-33.3	pathogenic
GRCh37/hg19 13q12.11-34(chr13:19571503-115092510)	copy number gain	See cases [RCV000449142]	Chr13:19571503..115092510 [GRCh37] Chr13:13q12.11-34	pathogenic
GRCh37/hg19 13q14.11-31.3(chr13:42457841-91796698)x1	copy number loss	See cases [RCV000446747]	Chr13:42457841..91796698 [GRCh37] Chr13:13q14.11-31.3	pathogenic
GRCh37/hg19 13q13.1-21.31(chr13:32946120-62698217)x1	copy number loss	See cases [RCV000446067]	Chr13:32946120..62698217 [GRCh37] Chr13:13q13.1-21.31	pathogenic
GRCh37/hg19 13q11-34(chr13:19436286-115107733)x3	copy number gain	See cases [RCV000445886]	Chr13:19436286..115107733 [GRCh37] Chr13:13q11-34	pathogenic
GRCh37/hg19 13q14.3(chr13:51786657-54834098)x1	copy number loss	not provided [RCV000509218]	Chr13:51786657..54834098 [GRCh37] Chr13:13q14.3	not provided
GRCh37/hg19 13q11-34(chr13:19436287-115107733)	copy number gain	See cases [RCV000510405]	Chr13:19436287..115107733 [GRCh37] Chr13:13q11-34	pathogenic
GRCh37/hg19 13q11-34(chr13:19436287-115107733)x3	copy number gain	See cases [RCV000511880]	Chr13:19436287..115107733 [GRCh37] Chr13:13q11-34	pathogenic
GRCh37/hg19 13q14.3-21.32(chr13:51939350-66854666)x3	copy number gain	not provided [RCV000683569]	Chr13:51939350..66854666 [GRCh37] Chr13:13q14.3-21.32	likely pathogenic
GRCh37/hg19 13q11-22.1(chr13:19436286-74045459)x3	copy number gain	not provided [RCV000683572]	Chr13:19436286..74045459 [GRCh37] Chr13:13q11-22.1	pathogenic
NC_000013.11:g.46968080_87381985del40413906	deletion	Chromosome 13q14 deletion syndrome [RCV000721955]	Chr13:46968080..87381985 [GRCh38] Chr13:13q14.2-31.2	pathogenic
Single allele	deletion	Intellectual disability [RCV000684766]	Chr13:48225451..58070399 [GRCh37] Chr13:13q14.2-21.1	likely pathogenic
GRCh37/hg19 13q11-34(chr13:19058717-115103529)x3	copy number gain	not provided [RCV000738115]	Chr13:19058717..115103529 [GRCh37] Chr13:13q11-34	pathogenic
GRCh37/hg19 13q11-34(chr13:19031237-115107157)x3	copy number gain	not provided [RCV000750643]	Chr13:19031237..115107157 [GRCh37] Chr13:13q11-34	pathogenic
GRCh37/hg19 13q14.2-21.2(chr13:49586017-61311845)x1	copy number loss	not provided [RCV000846575]	Chr13:49586017..61311845 [GRCh37] Chr13:13q14.2-21.2	uncertain significance
GRCh37/hg19 13q14.3-34(chr13:53262013-115107733)x1	copy number loss	not provided [RCV001006567]	Chr13:53262013..115107733 [GRCh37] Chr13:13q14.3-34	pathogenic
GRCh37/hg19 13q14.3-31.3(chr13:51512603-91631111)x1	copy number loss	not provided [RCV001006564]	Chr13:51512603..91631111 [GRCh37] Chr13:13q14.3-31.3	pathogenic
GRCh37/hg19 13q11-34(chr13:19436286-115107733)x3	copy number gain	not provided [RCV000849129]	Chr13:19436286..115107733 [GRCh37] Chr13:13q11-34	pathogenic
GRCh37/hg19 13q14.13-21.31(chr13:45819046-63910212)x1	copy number loss	not provided [RCV001795546]	Chr13:45819046..63910212 [GRCh37] Chr13:13q14.13-21.31	pathogenic
GRCh37/hg19 13p13-q34(chr13:1-115169878)x3	copy number gain	See cases [RCV001780076]	Chr13:1..115169878 [GRCh37] Chr13:13p13-q34	pathogenic
GRCh37/hg19 13q11-34(chr13:19436286-114981726)	copy number gain	not specified [RCV002053035]	Chr13:19436286..114981726 [GRCh37] Chr13:13q11-34	pathogenic
GRCh37/hg19 13q14.11-31.3(chr13:42457841-91796698)	copy number loss	not specified [RCV002053057]	Chr13:42457841..91796698 [GRCh37] Chr13:13q14.11-31.3	pathogenic
GRCh37/hg19 13q11-34(chr13:19436286-115107733)	copy number gain	not specified [RCV002053036]	Chr13:19436286..115107733 [GRCh37] Chr13:13q11-34	pathogenic
GRCh37/hg19 13q11-34(chr13:19436286-115107733)x3	copy number gain	not provided [RCV001834436]	Chr13:19436286..115107733 [GRCh37] Chr13:13q11-34	pathogenic
GRCh37/hg19 13q14.11-33.3(chr13:42504540-108206269)x3	copy number gain	not provided [RCV001829235]	Chr13:42504540..108206269 [GRCh37] Chr13:13q14.11-33.3	pathogenic
GRCh37/hg19 13q13.1-21.31(chr13:32946120-62698217)	copy number loss	not specified [RCV002053048]	Chr13:32946120..62698217 [GRCh37] Chr13:13q13.1-21.31	pathogenic
GRCh37/hg19 13q13.3-31.1(chr13:36376204-80681753)	copy number loss	not specified [RCV002053052]	Chr13:36376204..80681753 [GRCh37] Chr13:13q13.3-31.1	pathogenic
NM_006418.5(OLFM4):c.64T>G (p.Leu22Val)	single nucleotide variant	not specified [RCV004283723]	Chr13:53028900 [GRCh38] Chr13:53603035 [GRCh37] Chr13:13q14.3	uncertain significance
GRCh37/hg19 13p13-q34(chr13:1-115169878)	copy number gain	Complete trisomy 13 syndrome [RCV002280659]	Chr13:1..115169878 [GRCh37] Chr13:13p13-q34	pathogenic
GRCh37/hg19 13q11-34(chr13:19253848-115108937)x3	copy number gain	not provided [RCV002291540]	Chr13:19253848..115108937 [GRCh37] Chr13:13q11-34	pathogenic
NM_006418.5(OLFM4):c.991A>G (p.Thr331Ala)	single nucleotide variant	not specified [RCV004135819]	Chr13:53050229 [GRCh38] Chr13:53624364 [GRCh37] Chr13:13q14.3	uncertain significance
NM_006418.5(OLFM4):c.70G>C (p.Asp24His)	single nucleotide variant	not specified [RCV004149171]	Chr13:53028906 [GRCh38] Chr13:53603041 [GRCh37] Chr13:13q14.3	uncertain significance
NM_006418.5(OLFM4):c.121G>C (p.Asp41His)	single nucleotide variant	not specified [RCV004221777]	Chr13:53028957 [GRCh38] Chr13:53603092 [GRCh37] Chr13:13q14.3	uncertain significance
NM_006418.5(OLFM4):c.1424A>G (p.Gln475Arg)	single nucleotide variant	not specified [RCV004160649]	Chr13:53050662 [GRCh38] Chr13:53624797 [GRCh37] Chr13:13q14.3	likely benign
NM_006418.5(OLFM4):c.173G>A (p.Arg58His)	single nucleotide variant	not specified [RCV004209479]	Chr13:53029009 [GRCh38] Chr13:53603144 [GRCh37] Chr13:13q14.3	uncertain significance
NM_006418.5(OLFM4):c.622A>C (p.Asn208His)	single nucleotide variant	not specified [RCV004214349]	Chr13:53043156 [GRCh38] Chr13:53617291 [GRCh37] Chr13:13q14.3	uncertain significance
NM_006418.5(OLFM4):c.716C>T (p.Pro239Leu)	single nucleotide variant	not specified [RCV004109436]	Chr13:53043250 [GRCh38] Chr13:53617385 [GRCh37] Chr13:13q14.3	uncertain significance
NM_006418.5(OLFM4):c.1446C>G (p.Asn482Lys)	single nucleotide variant	not specified [RCV004175915]	Chr13:53050684 [GRCh38] Chr13:53624819 [GRCh37] Chr13:13q14.3	uncertain significance
NM_006418.5(OLFM4):c.292A>G (p.Arg98Gly)	single nucleotide variant	not specified [RCV004188569]	Chr13:53034435 [GRCh38] Chr13:53608570 [GRCh37] Chr13:13q14.3	uncertain significance
NM_006418.5(OLFM4):c.400C>G (p.Leu134Val)	single nucleotide variant	not specified [RCV004201436]	Chr13:53041952 [GRCh38] Chr13:53616087 [GRCh37] Chr13:13q14.3	uncertain significance
NM_006418.5(OLFM4):c.302G>A (p.Arg101His)	single nucleotide variant	not specified [RCV004181290]	Chr13:53034445 [GRCh38] Chr13:53608580 [GRCh37] Chr13:13q14.3	uncertain significance
NM_006418.5(OLFM4):c.332A>G (p.Gln111Arg)	single nucleotide variant	not specified [RCV004092400]	Chr13:53034475 [GRCh38] Chr13:53608610 [GRCh37] Chr13:13q14.3	uncertain significance
NM_006418.5(OLFM4):c.1303A>G (p.Met435Val)	single nucleotide variant	not specified [RCV004218244]	Chr13:53050541 [GRCh38] Chr13:53624676 [GRCh37] Chr13:13q14.3	uncertain significance
NM_006418.5(OLFM4):c.454A>G (p.Thr152Ala)	single nucleotide variant	not specified [RCV004263768]	Chr13:53042006 [GRCh38] Chr13:53616141 [GRCh37] Chr13:13q14.3	uncertain significance
NM_006418.5(OLFM4):c.835T>C (p.Ser279Pro)	single nucleotide variant	not specified [RCV004261693]	Chr13:53050073 [GRCh38] Chr13:53624208 [GRCh37] Chr13:13q14.3	uncertain significance
GRCh37/hg19 13q14.3(chr13:51768837-54900165)x1	copy number loss	not provided [RCV003483182]	Chr13:51768837..54900165 [GRCh37] Chr13:13q14.3	uncertain significance
GRCh37/hg19 13q14.11-21.2(chr13:44076923-60520078)x1	copy number loss	not specified [RCV003987012]	Chr13:44076923..60520078 [GRCh37] Chr13:13q14.11-21.2	pathogenic
GRCh37/hg19 13q13.2-21.1(chr13:35015723-59553519)x3	copy number gain	not specified [RCV003987040]	Chr13:35015723..59553519 [GRCh37] Chr13:13q13.2-21.1	pathogenic
GRCh37/hg19 13q14.2-32.2(chr13:49547974-98214905)x1	copy number loss	not specified [RCV003987008]	Chr13:49547974..98214905 [GRCh37] Chr13:13q14.2-32.2	pathogenic
GRCh37/hg19 13q14.2-14.3(chr13:50181731-54350061)x1	copy number loss	not provided [RCV004442840]	Chr13:50181731..54350061 [GRCh37] Chr13:13q14.2-14.3	uncertain significance
GRCh37/hg19 13q13.2-21.2(chr13:34884647-61309742)x1	copy number loss	not provided [RCV003885457]	Chr13:34884647..61309742 [GRCh37] Chr13:13q13.2-21.2	pathogenic
NM_006418.5(OLFM4):c.11G>A (p.Gly4Asp)	single nucleotide variant	not specified [RCV004499094]	Chr13:53028847 [GRCh38] Chr13:53602982 [GRCh37] Chr13:13q14.3	uncertain significance
NM_006418.5(OLFM4):c.131C>T (p.Ser44Phe)	single nucleotide variant	not specified [RCV004499096]	Chr13:53028967 [GRCh38] Chr13:53603102 [GRCh37] Chr13:13q14.3	uncertain significance
NM_006418.5(OLFM4):c.1405A>G (p.Ile469Val)	single nucleotide variant	not specified [RCV004499097]	Chr13:53050643 [GRCh38] Chr13:53624778 [GRCh37] Chr13:13q14.3	uncertain significance
NM_006418.5(OLFM4):c.223G>A (p.Gly75Ser)	single nucleotide variant	not specified [RCV004499098]	Chr13:53034366 [GRCh38] Chr13:53608501 [GRCh37] Chr13:13q14.3	uncertain significance
NM_006418.5(OLFM4):c.1244T>C (p.Leu415Pro)	single nucleotide variant	not specified [RCV004499095]	Chr13:53050482 [GRCh38] Chr13:53624617 [GRCh37] Chr13:13q14.3	uncertain significance
NM_006418.5(OLFM4):c.1115G>A (p.Arg372His)	single nucleotide variant	not specified [RCV004499093]	Chr13:53050353 [GRCh38] Chr13:53624488 [GRCh37] Chr13:13q14.3	uncertain significance
NM_006418.5(OLFM4):c.836C>T (p.Ser279Phe)	single nucleotide variant	not specified [RCV004499099]	Chr13:53050074 [GRCh38] Chr13:53624209 [GRCh37] Chr13:13q14.3	uncertain significance

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	484
Count of miRNA genes:	384
Interacting mature miRNAs:	425
Transcripts:	ENST00000219022
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCh38)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
406921416	GWAS570392_H	unipolar depression QTL GWAS570392 (human)		2e-10	depressive symptom measurement		13	53051646	53051647	Human
2289192	BW359_H	Body weight QTL 359 (human)		0.0344	Body fat amount	percent fat	13	49989404	75989404	Human
406977678	GWAS626654_H	depressive symptom measurement QTL GWAS626654 (human)		4e-11	depressive symptom measurement		13	53051646	53051647	Human
406997587	GWAS646563_H	unipolar depression QTL GWAS646563 (human)		8e-09	unipolar depression		13	53051646	53051647	Human
407328596	GWAS977572_H	insomnia QTL GWAS977572 (human)		3e-37	insomnia		13	53051646	53051647	Human
407328595	GWAS977571_H	insomnia QTL GWAS977571 (human)		3e-14	insomnia		13	53039855	53039856	Human
407328594	GWAS977570_H	insomnia QTL GWAS977570 (human)		2e-16	insomnia		13	53035942	53035943	Human
407328593	GWAS977569_H	insomnia QTL GWAS977569 (human)		2e-08	insomnia		13	53034753	53034754	Human
407055316	GWAS704292_H	insomnia measurement QTL GWAS704292 (human)		9e-10	insomnia measurement		13	53039855	53039856	Human
406953307	GWAS602283_H	liver fat measurement QTL GWAS602283 (human)		0.000004	liver lipid amount (VT:0010764)	liver fat morphological measurement (CMO:0002187)	13	53043174	53043175	Human
407021657	GWAS670633_H	self reported educational attainment QTL GWAS670633 (human)		5e-09	self reported educational attainment		13	53051646	53051647	Human
407017881	GWAS666857_H	unipolar depression QTL GWAS666857 (human)		6e-19	unipolar depression		13	53051646	53051647	Human
407223321	GWAS872297_H	insomnia QTL GWAS872297 (human)		1e-09	insomnia		13	53035836	53035837	Human
406978783	GWAS627759_H	intelligence QTL GWAS627759 (human)		0.000003	intelligence		13	53039196	53039197	Human
407223323	GWAS872299_H	insomnia QTL GWAS872299 (human)		1e-19	insomnia		13	53051646	53051647	Human
407223322	GWAS872298_H	insomnia QTL GWAS872298 (human)		3e-09	insomnia		13	53039855	53039856	Human
407062563	GWAS711539_H	obsessive-compulsive disorder, attention deficit hyperactivity disorder, Tourette syndrome, unipolar depression, bipolar disorder, autism spectrum disorder, schizophrenia, anorexia nervosa QTL GWAS711539 (human)		1e-08	obsessive-compulsive disorder, attention deficit hyperactivity disorder, Tourette syndrome, unipolar depression, bipolar disorder, autism spectrum disorder, schizophrenia, anorexia nervosa		13	53051646	53051647	Human
407004003	GWAS652979_H	self reported educational attainment QTL GWAS652979 (human)		2e-09	self reported educational attainment		13	53040419	53040420	Human
406974247	GWAS623223_H	sporadic amyotrophic lateral sclerosis QTL GWAS623223 (human)		0.0000001	sporadic amyotrophic lateral sclerosis		13	53039424	53039425	Human
407232291	GWAS881267_H	bone density QTL GWAS881267 (human)		7e-32	bone mineral mass (VT:0005007)	bone mineral density (CMO:0001226)	13	53041610	53041611	Human
406908783	GWAS557759_H	unipolar depression, bipolar disorder QTL GWAS557759 (human)		1e-23	unipolar depression, bipolar disorder		13	53051646	53051647	Human
407056626	GWAS705602_H	unipolar depression, autism spectrum disorder QTL GWAS705602 (human)		4e-08	unipolar depression, autism spectrum disorder		13	53051646	53051647	Human
2292823	PRSTS88_H	Prostate tumor susceptibility QTL 88 (human)			Prostate tumor susceptibility		13	41532058	67532058	Human
1643298	BW212_H	Body weight QTL 212 (human)	2.67	0.0002	Body weight	BMI	13	41532058	67532058	Human
406948858	GWAS597834_H	trans fatty acid measurement, trans-16:1n-7 fatty acid measurement QTL GWAS597834 (human)		0.000004	trans fatty acid measurement, trans-16:1n-7 fatty acid measurement	milk trans fatty acid measurement (CMO:0000824)	13	53031100	53031101	Human
406921018	GWAS569994_H	unipolar depression QTL GWAS569994 (human)		4e-08	unipolar depression		13	53039855	53039856	Human
407097592	GWAS746568_H	intelligence QTL GWAS746568 (human)		3e-08	intelligence		13	53051646	53051647	Human
407360888	GWAS1009864_H	insomnia QTL GWAS1009864 (human)		2e-09	insomnia		13	53032724	53032725	Human

Markers in Region

RH66409

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	13	53,626,012 - 53,626,164	UniSTS	GRCh37
Build 36	13	52,524,013 - 52,524,165	RGD	NCBI36
Celera	13	34,612,063 - 34,612,215	RGD
Cytogenetic Map	13	q14.3	UniSTS
HuRef	13	34,340,397 - 34,340,549	UniSTS
GeneMap99-GB4 RH Map	13	158.06	UniSTS

A002P14

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	13	53,626,002 - 53,626,127	UniSTS	GRCh37
Build 36	13	52,524,003 - 52,524,128	RGD	NCBI36
Celera	13	34,612,053 - 34,612,178	RGD
Cytogenetic Map	13	q14.3	UniSTS
HuRef	13	34,340,387 - 34,340,512	UniSTS
GeneMap99-GB4 RH Map	13	157.96	UniSTS
NCBI RH Map	13	489.5	UniSTS

OLFM4_9141

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	13	53,625,469 - 53,626,352	UniSTS	GRCh37
Build 36	13	52,523,470 - 52,524,353	RGD	NCBI36
Celera	13	34,611,520 - 34,612,403	RGD
HuRef	13	34,339,854 - 34,340,737	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	entire extraembryonic component	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	pharyngeal arch	renal system	reproductive system	respiratory system	sensory system
1195	2359	2760	2190	4606	1532	1997	3	475	1351	313	2024	6339	5796	20	3621	1	719	1611	1417	167

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_006418	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AF097021	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AI560739	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK000683	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK300947	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AL390736	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY358567	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC047740	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC117329	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH471124	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CP068265	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DA928098	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KT584104	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENST00000219022 ⟹ ENSP00000219022

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	13	53,028,813 - 53,052,057 (+)	Ensembl

RefSeq Acc Id:

NM_006418 ⟹ NP_006409

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	13	53,028,813 - 53,052,057 (+)	NCBI
GRCh37	13	53,602,876 - 53,626,196 (+)	ENTREZGENE
Build 36	13	52,500,973 - 52,524,193 (+)	NCBI Archive
HuRef	13	34,317,261 - 34,340,581 (+)	ENTREZGENE
CHM1_1	13	53,570,960 - 53,594,281 (+)	NCBI
T2T-CHM13v2.0	13	52,244,407 - 52,267,681 (+)	NCBI

Sequence:

show sequence

AGCGGCTCCAGCTAAGAGGACAAGATGAGGCCCGGCCTCTCATTTCTCCTAGCCCTTCTGTTCT
TCCTTGGCCAAGCTGCAGGGGATTTGGGGGATGTGGGACCTCCAATTCCCAGCCCCGGCTTCAG
CTCTTTCCCAGGTGTTGACTCCAGCTCCAGCTTCAGCTCCAGCTCCAGGTCGGGCTCCAGCTCC
AGCCGCAGCTTAGGCAGCGGAGGTTCTGTGTCCCAGTTGTTTTCCAATTTCACCGGCTCCGTGG
ATGACCGTGGGACCTGCCAGTGCTCTGTTTCCCTGCCAGACACCACCTTTCCCGTGGACAGAGT
GGAACGCTTGGAATTCACAGCTCATGTTCTTTCTCAGAAGTTTGAGAAAGAACTTTCCAAAGTG
AGGGAATATGTCCAATTAATTAGTGTGTATGAAAAGAAACTGTTAAACCTAACTGTCCGAATTG
ACATCATGGAGAAGGATACCATTTCTTACACTGAACTGGACTTCGAGCTGATCAAGGTAGAAGT
GAAGGAGATGGAAAAACTGGTCATACAGCTGAAGGAGAGTTTTGGTGGAAGCTCAGAAATTGTT
GACCAGCTGGAGGTGGAGATAAGAAATATGACTCTCTTGGTAGAGAAGCTTGAGACACTAGACA
AAAACAATGTCCTTGCCATTCGCCGAGAAATCGTGGCTCTGAAGACCAAGCTGAAAGAGTGTGA
GGCCTCTAAAGATCAAAACACCCCTGTCGTCCACCCTCCTCCCACTCCAGGGAGCTGTGGTCAT
GGTGGTGTGGTGAACATCAGCAAACCGTCTGTGGTTCAGCTCAACTGGAGAGGGTTTTCTTATC
TATATGGTGCTTGGGGTAGGGATTACTCTCCCCAGCATCCAAACAAAGGACTGTATTGGGTGGC
GCCATTGAATACAGATGGGAGACTGTTGGAGTATTATAGACTGTACAACACACTGGATGATTTG
CTATTGTATATAAATGCTCGAGAGTTGCGGATCACCTATGGCCAAGGTAGTGGTACAGCAGTTT
ACAACAACAACATGTACGTCAACATGTACAACACCGGGAATATTGCCAGAGTTAACCTGACCAC
CAACACGATTGCTGTGACTCAAACTCTCCCTAATGCTGCCTATAATAACCGCTTTTCATATGCT
AATGTTGCTTGGCAAGATATTGACTTTGCTGTGGATGAGAATGGATTGTGGGTTATTTATTCAA
CTGAAGCCAGCACTGGTAACATGGTGATTAGTAAACTCAATGACACCACACTTCAGGTGCTAAA
CACTTGGTATACCAAGCAGTATAAACCATCTGCTTCTAACGCCTTCATGGTATGTGGGGTTCTG
TATGCCACCCGTACTATGAACACCAGAACAGAAGAGATTTTTTACTATTATGACACAAACACAG
GGAAAGAGGGCAAACTAGACATTGTAATGCATAAGATGCAGGAAAAAGTGCAGAGCATTAACTA
TAACCCTTTTGACCAGAAACTTTATGTCTATAACGATGGTTACCTTCTGAATTATGATCTTTCT
GTCTTGCAGAAGCCCCAGTAAGCTGTTTAGGAGTTAGGGTGAAAGAGAAAATGTTTGTTGAAAA
AATAGTCTTCTCCACTTACTTAGATATCTGCAGGGGTGTCTAAAAGTGTGTTCATTTTGCAGCA
ATGTTTAGGTGCATAGTTCTACCACACTAGAGATCTAGGACATTTGTCTTGATTTGGTGAGTTC
TCTTGGGAATCATCTGCCTCTTCAGGCGCATTTTGCAATAAAGTCTGTCTAGGGTGGGATTGTC
AGAGGTCTAGGGGCACTGTGGGCCTAGTGAAGCCTACTGTGAGGAGGCTTCACTAGAAGCCTTA
AATTAGGAATTAAGGAACTTAAAACTCAGTATGGCGTCTAGGGATTCTTTGTACAGGAAATATT
GCCCAATGACTAGTCCTCATCCATGTAGCACCACTAATTCTTCCATGCCTGGAAGAAACCTGGG
GACTTAGTTAGGTAGATTAATATCTGGAGCTCCTCGAGGGACCAAATCTCCAACTTTTTTTTCC
CCTCACTAGCACCTGGAATGATGCTTTGTATGTGGCAGATAAGTAAATTTGGCATGCTTATATA
TTCTACATCTGTAAAGTGCTGAGTTTTATGGAGAGAGGCCTTTTTATGCATTAAATTGTACATG
GCAAATAAATCCCAGAAGGATCTGTAGATGAGGCACCTGCTTTTTCTTTTCTCTCATTGTCCAC
CTTACTAAAAGTCAGTAGAATCTTCTACCTCATAACTTCCTTCCAAAGGCAGCTCAGAAGATTA
GAACCAGACTTACTAACCAATTCCACCCCCCACCAACCCCCTTCTACTGCCTACTTTAAAAAAA
TTAATAGTTTTCTATGGAACTGATCTAAGATTAGAAAAATTAATTTTCTTTAATTTCATTATGA
ACTTTTATTTACATGACTCTAAGACTATAAGAAAATCTGATGGCAGTGACAAAGTGCTAGCATT
TATTGTTATCTAATAAAGACCTTGGAGCATATGTGCAACTTATGAGTGTATCAGTTGTTGCATG
TAATTTTTGCCTTTGTTTAAGCCTGGAACTTGTAAGAAAATGAAAATTTAATTTTTTTTTCTAG
GACGAGCTATAGAAAAGCTATTGAGAGTATCTAGTTAATCAGTGCAGTAGTTGGAAACCTTGCT
GGTGTATGTGATGTGCTTCTGTGCTTTTGAATGACTTTATCATCTAGTCTTTGTCTATTTTTCC
TTTGATGTTCAAGTCCTAGTCTATAGGATTGGCAGTTTAAATGCTTTACTCCCCCTTTTAAAAT
AAATGATTAAAATGTGCTTTGAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_006409	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAC72970	(Get FASTA)	NCBI Sequence Viewer
	AAH47740	(Get FASTA)	NCBI Sequence Viewer
	AAI17330	(Get FASTA)	NCBI Sequence Viewer
	AAQ88930	(Get FASTA)	NCBI Sequence Viewer
	BAG62576	(Get FASTA)	NCBI Sequence Viewer
	EAW52052	(Get FASTA)	NCBI Sequence Viewer
	EAW52053	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSP00000219022
	ENSP00000219022.2
GenBank Protein	Q6UX06	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_006409 ⟸ NM_006418
- Peptide Label:	precursor
- UniProtKB:	Q5VWG0 (UniProtKB/Swiss-Prot), O95362 (UniProtKB/Swiss-Prot), Q86T22 (UniProtKB/Swiss-Prot), Q6UX06 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MRPGLSFLLALLFFLGQAAGDLGDVGPPIPSPGFSSFPGVDSSSSFSSSSRSGSSSSRSLGSGG SVSQLFSNFTGSVDDRGTCQCSVSLPDTTFPVDRVERLEFTAHVLSQKFEKELSKVREYVQLIS VYEKKLLNLTVRIDIMEKDTISYTELDFELIKVEVKEMEKLVIQLKESFGGSSEIVDQLEVEIR NMTLLVEKLETLDKNNVLAIRREIVALKTKLKECEASKDQNTPVVHPPPTPGSCGHGGVVNISK PSVVQLNWRGFSYLYGAWGRDYSPQHPNKGLYWVAPLNTDGRLLEYYRLYNTLDDLLLYINARE LRITYGQGSGTAVYNNNMYVNMYNTGNIARVNLTTNTIAVTQTLPNAAYNNRFSYANVAWQDID FAVDENGLWVIYSTEASTGNMVISKLNDTTLQVLNTWYTKQYKPSASNAFMVCGVLYATRTMNT RTEEIFYYYDTNTGKEGKLDIVMHKMQEKVQSINYNPFDQKLYVYNDGYLLNYDLSVLQKPQ hide sequence

Ensembl Acc Id:

ENSP00000219022 ⟸ ENST00000219022

Protein Domains

Olfactomedin-like

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q6UX06-F1-model_v2	AlphaFold	Q6UX06	1-510	view protein structure

Promoters

RGD ID:

7226531

Promoter ID:

EPDNEW_H19012

Type:

multiple initiation site

Name:

OLFM4_1

Description:

olfactomedin 4

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	13	53,028,813 - 53,028,873	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	HGNC:17190	AgrOrtholog
COSMIC	OLFM4	COSMIC
Ensembl Genes	ENSG00000102837	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENST00000219022	ENTREZGENE
	ENST00000219022.3	UniProtKB/Swiss-Prot
GTEx	ENSG00000102837	GTEx
HGNC ID	HGNC:17190	ENTREZGENE
Human Proteome Map	OLFM4	Human Proteome Map
InterPro	Olfac-like_dom	UniProtKB/Swiss-Prot
	Olfactomedin-like_domain	UniProtKB/Swiss-Prot
	Quinoprot_gluc/sorb_DH	UniProtKB/Swiss-Prot
KEGG Report	hsa:10562	UniProtKB/Swiss-Prot
NCBI Gene	10562	ENTREZGENE
OMIM	614061	OMIM
PANTHER	OLFACTOMEDIN-RELATED	UniProtKB/Swiss-Prot
	PTHR23192:SF7	UniProtKB/Swiss-Prot
Pfam	OLF	UniProtKB/Swiss-Prot
PharmGKB	PA134984745	PharmGKB
PROSITE	OLF	UniProtKB/Swiss-Prot
SMART	OLF	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF50952	UniProtKB/Swiss-Prot
UniProt	O95362	ENTREZGENE
	OLFM4_HUMAN	UniProtKB/Swiss-Prot
	Q5VWG0	ENTREZGENE
	Q6UX06	ENTREZGENE
	Q86T22	ENTREZGENE
UniProt Secondary	O95362	UniProtKB/Swiss-Prot
	Q5VWG0	UniProtKB/Swiss-Prot
	Q86T22	UniProtKB/Swiss-Prot

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Human Phenotype Annotations - ClinVar

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

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