Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: RIPK4 (receptor interacting serine/threonine kinase 4) Homo sapiens
Symbol: RIPK4
Name: receptor interacting serine/threonine kinase 4
Description: Predicted to have ATP binding activity and protein serine/threonine kinase activity. Involved in morphogenesis of an epithelium and positive regulation of NF-kappaB transcription factor activity. Predicted to localize to cytoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ANKK2; ANKRD3; ankyrin repeat domain 3; ankyrin repeat domain-containing protein 3; CHANDS; DIK; MGC129992; MGC129993; NKRD3; PKC-delta-interacting protein kinase; PKK; PPS2; protein kinase C-associated kinase; receptor-interacting serine-threonine kinase 4; receptor-interacting serine/threonine-protein kinase 4; RIP4; serine/threonine-protein kinase ANKRD3
Mus musculus (house mouse) : Ripk4 (receptor-interacting serine-threonine kinase 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ripk4 (receptor-interacting serine-threonine kinase 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ripk4 (receptor interacting serine/threonine kinase 4)
Pan paniscus (bonobo/pygmy chimpanzee) : RIPK4 (receptor interacting serine/threonine kinase 4)
Canis lupus familiaris (dog) : RIPK4 (receptor interacting serine/threonine kinase 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ripk4 (receptor interacting serine/threonine kinase 4)
Sus scrofa (pig) : RIPK4 (receptor interacting serine/threonine kinase 4)
Chlorocebus sabaeus (African green monkey) : RIPK4 (receptor interacting serine/threonine kinase 4)
Heterocephalus glaber (naked mole-rat) : Ripk4 (receptor interacting serine/threonine kinase 4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl2141,739,369 - 41,767,089 (-)EnsemblGRCh38hg38GRCh38
GRCh382141,739,373 - 41,767,052 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372143,159,529 - 43,187,249 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362142,032,598 - 42,060,318 (-)NCBINCBI36hg18NCBI36
Build 342142,032,597 - 42,060,318NCBI
Celera2128,309,333 - 28,337,056 (-)NCBI
Cytogenetic Map21q22.3NCBI
HuRef2128,579,429 - 28,607,166 (-)NCBIHuRef
CHM1_12142,720,210 - 42,748,089 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on RIPK4
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1323281
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.