Tshz1 (teashirt zinc finger family member 1) - Rat Genome Database
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Gene: Tshz1 (teashirt zinc finger family member 1) Mus musculus
Analyze
Symbol: Tshz1
Name: teashirt zinc finger family member 1
RGD ID: 1323270
MGI Page MGI
Description: Predicted to have DNA binding activity and DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in anterior/posterior pattern specification; middle ear morphogenesis; and soft palate development. Predicted to localize to nucleus. Is expressed in several structures, including branchial arch; central nervous system; embryo mesenchyme; genitourinary system; and limb. Orthologous to human TSHZ1 (teashirt zinc finger homeobox 1); INTERACTS WITH 1,2-dichloroethane; 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 5730407I04Rik; D18Bwg1409e; KIAA4206; mKIAA4206; Mtsh; Mtsh1; NY-CO-; NY-CO-33; Sdccag; Sdccag33; serologically defined colon cancer antigen 3 homolog; serologically defined colon cancer antigen 33; teash; teashirt homolog 1; teashirt1; Tsh; Tsh1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391884,029,752 - 84,105,833 (-)NCBIGRCm39mm39
GRCm39 Ensembl1884,029,752 - 84,105,831 (-)Ensembl
GRCm381884,011,627 - 84,087,708 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1884,011,627 - 84,087,706 (-)EnsemblGRCm38mm10GRCm38
MGSCv371884,181,019 - 84,255,954 (-)NCBIGRCm37mm9NCBIm37
MGSCv361884,145,820 - 84,220,755 (-)NCBImm8
Celera1885,079,396 - 85,154,615 (-)NCBICelera
Cytogenetic Map18E4NCBI
cM Map1857.53NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleus  (IBA)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:10349636   PMID:10704881   PMID:11042159   PMID:11076861   PMID:11668608   PMID:12447396   PMID:12477932   PMID:14973285   PMID:15489334   PMID:15618518   PMID:15834955   PMID:16141072  
PMID:16141073   PMID:16631416   PMID:17586487   PMID:18287559   PMID:18701439   PMID:19030180   PMID:19343227   PMID:19386638   PMID:19745106   PMID:20059953   PMID:20096683   PMID:20843830  
PMID:21267068   PMID:21471366   PMID:21491433   PMID:21873635   PMID:23431145   PMID:24146773   PMID:24487590   PMID:24952961   PMID:25918232   PMID:26930384   PMID:27655933   PMID:28576773  
PMID:28981617   PMID:29031500   PMID:29255003   PMID:29967281   PMID:30104253   PMID:30796806   PMID:31427287   PMID:32234482  


Genomics

Comparative Map Data
Tshz1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391884,029,752 - 84,105,833 (-)NCBIGRCm39mm39
GRCm39 Ensembl1884,029,752 - 84,105,831 (-)Ensembl
GRCm381884,011,627 - 84,087,708 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1884,011,627 - 84,087,706 (-)EnsemblGRCm38mm10GRCm38
MGSCv371884,181,019 - 84,255,954 (-)NCBIGRCm37mm9NCBIm37
MGSCv361884,145,820 - 84,220,755 (-)NCBImm8
Celera1885,079,396 - 85,154,615 (-)NCBICelera
Cytogenetic Map18E4NCBI
cM Map1857.53NCBI
TSHZ1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1875,210,755 - 75,289,950 (+)EnsemblGRCh38hg38GRCh38
GRCh381875,210,797 - 75,289,946 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371872,922,752 - 73,001,899 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361871,051,719 - 71,130,889 (+)NCBINCBI36hg18NCBI36
Build 341871,125,160 - 71,130,665NCBI
Celera1869,741,400 - 69,820,597 (+)NCBI
Cytogenetic Map18q22.3NCBI
HuRef1869,607,516 - 69,686,785 (+)NCBIHuRef
CHM1_11872,917,366 - 72,997,125 (+)NCBICHM1_1
Tshz1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21877,376,399 - 77,452,315 (-)NCBI
Rnor_6.0 Ensembl1880,862,372 - 80,865,584 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01880,860,995 - 80,907,744 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01879,910,848 - 79,956,064 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41880,536,036 - 80,541,518 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11880,610,862 - 80,619,594 (-)NCBI
Celera1875,999,997 - 76,045,459 (-)NCBICelera
Cytogenetic Map18q12.3NCBI
Tshz1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495540258,695,150 - 58,717,926 (+)NCBIChiLan1.0ChiLan1.0
TSHZ1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11871,873,600 - 71,951,654 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1871,873,594 - 71,951,654 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01868,597,354 - 68,676,462 (+)NCBIMhudiblu_PPA_v0panPan3
TSHZ1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.114,224,875 - 4,229,755 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl14,226,210 - 4,246,762 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha15,232,697 - 5,310,574 (-)NCBI
ROS_Cfam_1.014,036,428 - 4,114,380 (-)NCBI
UMICH_Zoey_3.114,074,782 - 4,150,945 (-)NCBI
UNSW_CanFamBas_1.014,027,926 - 4,104,426 (-)NCBI
UU_Cfam_GSD_1.014,199,051 - 4,276,954 (-)NCBI
Tshz1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_ltri_2NW_02440494418,032,204 - 18,106,802 (-)NCBI
SpeTri2.0NW_0049366163,353,334 - 3,378,819 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TSHZ1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1148,902,346 - 148,984,832 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11148,905,179 - 148,984,984 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21164,830,580 - 164,837,213 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TSHZ1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1184,622,407 - 4,702,267 (-)NCBI
ChlSab1.1 Ensembl184,623,731 - 4,626,925 (-)Ensembl
Tshz1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248065,389,464 - 5,463,222 (-)NCBI

Position Markers
RH126143  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381884,084,009 - 84,084,257UniSTSGRCm38
MGSCv371884,253,401 - 84,253,649UniSTSGRCm37
Celera1885,151,978 - 85,152,226UniSTS
Cytogenetic Map18E4UniSTS
cM Map1856.0UniSTS
Whitehead/MRC_RH18983.15UniSTS
RH102961  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381884,011,633 - 84,011,828UniSTSGRCm38
MGSCv371884,181,025 - 84,181,220UniSTSGRCm37
Celera1885,079,402 - 85,079,597UniSTS
Cytogenetic Map18E4UniSTS
cM Map1856.0UniSTS
5730407I04Rik  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381884,012,623 - 84,012,869UniSTSGRCm38
MGSCv371884,182,015 - 84,182,261UniSTSGRCm37
Celera1885,080,394 - 85,080,640UniSTS
Cytogenetic Map18E4UniSTS
cM Map1855.0UniSTS
cM Map1856.0UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357639Obsty4_mobesity 4 (mouse)Not determined183948686184620653Mouse
1357630Tgq1_mtriglyceride QTL 1 (mouse)Not determined185091908584919240Mouse
11252137Modvl5_mmodifier of vacuolated lens 5 (mouse)185091908584919240Mouse
1302099Hdlq30_mHDL QTL 30 (mouse)Not determined185153522985535397Mouse
10412244Par5_mpulmonary adenoma resistance 5 (mouse)Not determined185153522985535397Mouse
1301853Heal9_mwound healing/regeneration 9 (mouse)Not determined185267220586672345Mouse
1301500Szs4_mseizure susceptibility 4 (mouse)Not determined185484280185496018Mouse
12880410V125Dq13_mvitamin D active form serum level QTL 13 (mouse)185630000090300000Mouse
12880430Fgf23lq4_mFGF23 serum level QTL 4 (mouse)185630000090300000Mouse
12880428V125Dq14_mvitamin D active form serum level QTL 14 (mouse)185730000090702639Mouse
1301353Lbw6_mlupus NZB x NZW 6 (mouse)Not determined185742926790702639Mouse
4140971Mbmq1_mmale body mass QTL 1 (mouse)Not determined5785721090702639Mouse
11039492Ltpr8a_mLeishmania tropica response 8a (mouse)185904702190702639Mouse
11039495Ltpr8c_mLeishmania tropica response 8c (mouse)185904702190702639Mouse
11049564Lmr29_mleishmaniasis resistance 29 (mouse)185904702190702639Mouse
1301103Pgia11_mproteoglycan induced arthritis 11 (mouse)Not determined185982648990702639Mouse
1302109Sluc28_msusceptibility to lung cancer 28 (mouse)Not determined185984762690702639Mouse
1301798Hdlq31_mHDL QTL 31 (mouse)Not determined186712626490702639Mouse
10401904Sicd4_mseizure-induced cell death 4 (mouse)Not determined186967220585496018Mouse
15014786Mvlq2_mmacrovesicular liver lesion QTL 2 (mouse)187155126490702639Mouse
1302183Pas7_mpulmonary adenoma susceptibility 7 (mouse)Not determined187261252384126470Mouse
4142153Idd21.1_minsulin dependent diabetes susceptibility 21.1 (mouse)Not determined187442926784126470Mouse
4141757Sicd1_mseizure-induced cell death 1 (mouse)Not determined188013204989572790Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:337
Count of miRNA genes:247
Interacting mature miRNAs:266
Transcripts:ENSMUST00000060303, ENSMUST00000175783
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001081300 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001364993 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001364994 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030250273 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030250274 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030250275 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC124012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF191309 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK017514 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK152140 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK220545 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC017636 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC038610 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC040215 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC049795 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC049799 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC058264 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ130710 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000060303   ⟹   ENSMUSP00000089388
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1884,011,627 - 84,086,404 (-)Ensembl
RefSeq Acc Id: ENSMUST00000175783   ⟹   ENSMUSP00000157454
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1884,012,082 - 84,086,451 (-)Ensembl
RefSeq Acc Id: ENSMUST00000235188
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1884,015,818 - 84,085,075 (-)Ensembl
RefSeq Acc Id: ENSMUST00000237918
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1884,015,867 - 84,087,706 (-)Ensembl
RefSeq Acc Id: NM_001081300   ⟹   NP_001074769
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391884,029,752 - 84,104,590 (-)NCBI
GRCm381884,011,627 - 84,086,465 (-)NCBI
MGSCv371884,181,019 - 84,255,954 (-)RGD
Celera1885,079,396 - 85,154,615 (-)RGD
cM Map18 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001364993   ⟹   NP_001351922
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391884,029,752 - 84,105,833 (-)NCBI
GRCm381884,011,627 - 84,087,708 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001364994   ⟹   NP_001351923
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391884,029,752 - 84,104,590 (-)NCBI
GRCm381884,011,627 - 84,086,465 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030250273   ⟹   XP_030106133
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391884,029,756 - 84,105,757 (-)NCBI
GRCm381884,011,631 - 84,087,632 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030250274   ⟹   XP_030106134
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391884,029,756 - 84,105,699 (-)NCBI
GRCm381884,011,631 - 84,087,545 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030250275   ⟹   XP_030106135
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391884,029,756 - 84,105,832 (-)NCBI
GRCm381884,011,631 - 84,087,707 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_001074769   ⟸   NM_001081300
- Peptide Label: isoform 1
- UniProtKB: Q5DTH5 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001351922   ⟸   NM_001364993
- Peptide Label: isoform 2
RefSeq Acc Id: NP_001351923   ⟸   NM_001364994
- Peptide Label: isoform 2
RefSeq Acc Id: XP_030106135   ⟸   XM_030250275
- Peptide Label: isoform X1
RefSeq Acc Id: XP_030106133   ⟸   XM_030250273
- Peptide Label: isoform X1
RefSeq Acc Id: XP_030106134   ⟸   XM_030250274
- Peptide Label: isoform X1
RefSeq Acc Id: ENSMUSP00000089388   ⟸   ENSMUST00000060303
RefSeq Acc Id: ENSMUSP00000157454   ⟸   ENSMUST00000175783
Protein Domains
C2H2-type

Promoters
RGD ID:13678284
Promoter ID:EPDNEW_M23291
Type:single initiation site
Name:Tshz1_2
Description:Mus musculus teashirt zinc finger family member 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M23292  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381884,086,264 - 84,086,324EPDNEW
RGD ID:13678286
Promoter ID:EPDNEW_M23292
Type:initiation region
Name:Tshz1_1
Description:Mus musculus teashirt zinc finger family member 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M23291  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381884,086,465 - 84,086,525EPDNEW
RGD ID:6829595
Promoter ID:MM_KWN:25859
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lung
Transcripts:ENSMUST00000114667
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361884,182,661 - 84,183,161 (-)MPROMDB
RGD ID:6829597
Promoter ID:MM_KWN:25860
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:NM_001081300,   UC008FUL.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361884,255,076 - 84,256,932 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1346031 AgrOrtholog
Ensembl Genes ENSMUSG00000046982 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000089388 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000157454 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000060303 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000175783 ENTREZGENE, UniProtKB/TrEMBL
InterPro Homeobox_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Homeodomain-like UniProtKB/TrEMBL
  Teashirt_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tshz1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:110796 UniProtKB/Swiss-Prot
MGD MGI:1346031 ENTREZGENE
NCBI Gene 110796 ENTREZGENE
PANTHER PTHR12487 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR12487:SF6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Tshz1 PhenoGen
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART HOX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZnF_C2H2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF46689 UniProtKB/TrEMBL
UniProt A0A494B920_MOUSE UniProtKB/TrEMBL
  Q5DTH5 ENTREZGENE
  Q9CS91_MOUSE UniProtKB/TrEMBL
  TSH1_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q6PE60 UniProtKB/Swiss-Prot
  Q8VD19 UniProtKB/Swiss-Prot
  Q9JLD5 UniProtKB/Swiss-Prot