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Gene: RIOK2 (RIO kinase 2) Homo sapiens
Symbol: RIOK2
Name: RIO kinase 2
Description: Predicted to have protein kinase activity. Involved in several processes, including maturation of SSU-rRNA; positive regulation of ribosome biogenesis; and regulation of mitotic metaphase/anaphase transition. Localizes to the cytoplasm and preribosome, small subunit precursor; PARTICIPATES IN ribosome biogenesis pathway; INTERACTS WITH 2-methylcholine; 3-isobutyl-1-methyl-7H-xanthine; antirheumatic drug.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: FLJ11159; RIO2; serine/threonine-protein kinase RIO2
Mus musculus (house mouse) : Riok2 (RIO kinase 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Riok2 (RIO kinase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Riok2 (RIO kinase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : RIOK2 (RIO kinase 2)
Canis lupus familiaris (dog) : RIOK2 (RIO kinase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Riok2 (RIO kinase 2)
Sus scrofa (pig) : RIOK2 (RIO kinase 2)
Chlorocebus sabaeus (African green monkey) : RIOK2 (RIO kinase 2)
Heterocephalus glaber (naked mole-rat) : Riok2 (RIO kinase 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl597,160,867 - 97,183,247 (-)Ensembl
GRCh38597,160,867 - 97,183,247 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37596,496,571 - 96,519,005 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36596,524,397 - 96,544,700 (-)NCBINCBI36hg18NCBI36
Build 34596,524,396 - 96,544,700NCBI
Celera592,380,971 - 92,403,748 (-)NCBI
Cytogenetic Map5q15NCBI
HuRef591,686,274 - 91,709,022 (-)NCBIHuRef
CHM1_1595,929,175 - 95,951,630 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on RIOK2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1323125
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.