Vrk2 (vaccinia related kinase 2) - Rat Genome Database

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Gene: Vrk2 (vaccinia related kinase 2) Mus musculus
Analyze
Symbol: Vrk2
Name: vaccinia related kinase 2
RGD ID: 1323121
MGI Page MGI
Description: Enables protein serine/threonine kinase activity. Predicted to be involved in cellular response to oxidative stress; regulation of signal transduction; and signal transduction. Predicted to act upstream of or within phosphorylation. Located in endoplasmic reticulum; membrane; and nuclear envelope. Is expressed in several structures, including cerebral cortex; dorsal mesogastrium; gonad; hemolymphoid system; and yolk sac. Orthologous to human VRK2 (VRK serine/threonine kinase 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 2810003O05Rik; AI447698; serine/threonine-protein kinase VRK2; vaccinia virus BIR kinase related kinase 2; vaccinia-related kinase 2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391126,421,398 - 26,544,006 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1126,421,322 - 26,543,999 (-)EnsemblGRCm39 Ensembl
GRCm381126,471,398 - 26,594,012 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1126,471,322 - 26,593,999 (-)EnsemblGRCm38mm10GRCm38
MGSCv371126,371,401 - 26,493,920 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361126,503,981 - 26,625,366 (-)NCBIMGSCv36mm8
MGSCv361126,371,404 - 26,493,611 (-)NCBIMGSCv36mm8
Celera1128,995,024 - 28,995,410 (+)NCBICelera
Celera1137,253,803 - 37,372,542 (-)NCBICelera
Cytogenetic Map11A3.3NCBI
cM Map1115.94NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:12417526   PMID:12477932   PMID:12782311   PMID:14645249   PMID:15489334   PMID:15782199   PMID:16141072   PMID:16141073  
PMID:16462940   PMID:16919269   PMID:17709393   PMID:21267068   PMID:21677750   PMID:21873635   PMID:22572157   PMID:25755282   PMID:28378742   PMID:30488434   PMID:31050055   PMID:31142202  
PMID:32325033   PMID:32554809   PMID:32583282   PMID:33785841   PMID:34321999   PMID:35173553   PMID:37452335  


Genomics

Comparative Map Data
Vrk2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391126,421,398 - 26,544,006 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1126,421,322 - 26,543,999 (-)EnsemblGRCm39 Ensembl
GRCm381126,471,398 - 26,594,012 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1126,471,322 - 26,593,999 (-)EnsemblGRCm38mm10GRCm38
MGSCv371126,371,401 - 26,493,920 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361126,503,981 - 26,625,366 (-)NCBIMGSCv36mm8
MGSCv361126,371,404 - 26,493,611 (-)NCBIMGSCv36mm8
Celera1128,995,024 - 28,995,410 (+)NCBICelera
Celera1137,253,803 - 37,372,542 (-)NCBICelera
Cytogenetic Map11A3.3NCBI
cM Map1115.94NCBI
VRK2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38257,907,592 - 58,159,920 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl257,907,629 - 58,159,920 (+)EnsemblGRCh38hg38GRCh38
GRCh37258,134,727 - 58,387,055 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36258,127,224 - 58,240,510 (+)NCBINCBI36Build 36hg18NCBI36
Build 34258,185,476 - 58,298,654NCBI
Celera258,116,828 - 58,230,225 (+)NCBICelera
Cytogenetic Map2p16.1NCBI
HuRef258,014,875 - 58,128,335 (+)NCBIHuRef
CHM1_1258,203,888 - 58,317,318 (+)NCBICHM1_1
T2T-CHM13v2.0257,912,292 - 58,164,754 (+)NCBIT2T-CHM13v2.0
Vrk2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr814104,514,815 - 104,635,549 (-)NCBIGRCr8
mRatBN7.214100,313,771 - 100,434,520 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl14100,313,601 - 100,434,527 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx14104,646,638 - 104,767,362 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.014105,890,724 - 106,011,446 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.014102,362,554 - 102,483,276 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.014110,739,835 - 110,883,836 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl14110,739,226 - 110,883,803 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.014110,554,902 - 110,576,584 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.014110,444,503 - 110,501,306 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.414107,287,844 - 107,450,960 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.114107,300,490 - 107,470,542 (-)NCBI
Celera1499,260,139 - 99,368,196 (-)NCBICelera
Cytogenetic Map14q22NCBI
Vrk2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542425,282,007 - 25,399,348 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542425,307,221 - 25,397,900 (-)NCBIChiLan1.0ChiLan1.0
VRK2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21268,197,958 - 68,310,907 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A68,201,910 - 68,314,773 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A58,158,347 - 58,271,245 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A59,166,949 - 59,419,895 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A59,305,233 - 59,419,895 (+)Ensemblpanpan1.1panPan2
VRK2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11058,432,144 - 58,544,189 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1058,431,978 - 58,544,189 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1058,280,905 - 58,497,135 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01059,332,186 - 59,547,978 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1059,435,778 - 59,547,970 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11059,029,154 - 59,244,640 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01059,313,317 - 59,529,195 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01059,606,236 - 59,821,676 (+)NCBIUU_Cfam_GSD_1.0
Vrk2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629224,418,835 - 24,615,182 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364913,958,588 - 4,057,738 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364913,956,171 - 4,057,753 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
VRK2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl383,433,313 - 83,536,980 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1383,435,250 - 83,537,022 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2388,020,677 - 88,122,044 (-)NCBISscrofa10.2Sscrofa10.2susScr3
VRK2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11448,803,149 - 48,909,144 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1448,798,499 - 48,906,712 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604562,835,754 - 62,944,601 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Vrk2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248333,663,641 - 3,776,404 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248333,663,606 - 3,778,598 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Vrk2
4103 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:464
Count of miRNA genes:324
Interacting mature miRNAs:356
Transcripts:ENSMUST00000078362, ENSMUST00000109504, ENSMUST00000124294, ENSMUST00000125545, ENSMUST00000133487, ENSMUST00000155728, ENSMUST00000156264
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10044008Hbnr15_mHeligmosomoides bakeri nematode resistance 15 (mouse)Not determined1122705234227232Mouse
1300599Cocrb11_mcocaine related behavior 11 (mouse)Not determined11267035536671472Mouse
27095904Scvln12_msacral vertebrae length 2, 10 week (mouse)11325000034495048Mouse
27095909Scvln6_msacral vertebrae length 2, 5 week (mouse)11325000044090827Mouse
27226798Scvln18_msacral vertebrae length 2, 16 week (mouse)11325000060690826Mouse
26884446Sklq10_mskull length QTL 10, 10 week (mouse)11325000062890826Mouse
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11325000072690826Mouse
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
27226741Metcl5_mmetatarsal-calcaneal length 5, 5 week (mouse)11465000046290827Mouse
27226735Metcl16_mmetatarsal-calcaneal length 16, 16 week (mouse)11525000035090827Mouse
1357518Tgyl1_mtriglyceride level 1 (mouse)Not determined11688027733916219Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
1300990Bits3_mbitterness sensitivity 3 (mouse)Not determined11837212142372260Mouse
27226738Metcl11_mmetatarsal-calcaneal length 11, 10 week (mouse)11885000061390826Mouse
1302171Pgia28_mproteoglycan induced arthritis 28 (mouse)Not determined11890609742906218Mouse
4141047Nilac1_mnicotine induced locomotor activity 1 (mouse)Not determined11901178043011942Mouse
13524844Ppiq9_mprepulse inhibition QTL 9 (mouse)11904999735077325Mouse
13463472Mcvq15_mmean corpuscular volume QTL 15 (mouse)111095123244951464Mouse
13463479Mchq19_mmean corpuscular hemoglobin QTL 19 (mouse)111095123244951464Mouse
26884401Huml4_mhumerus length 4, 10 week (mouse)111155000068490826Mouse
27226762Feml21_mfemur length 21, 16 week (mouse)111175000065990826Mouse
10412216Eae44_mexperimental allergic encephalomyelitis susceptibility 44 (mouse)Not determined111226863739950840Mouse
1357640Orq2_movulation rate QTL 2 (mouse)Not determined111226863768500330Mouse
4141127W3q4_mweight 3 weeks QTL 4 (mouse)Not determined1226863768500330Mouse
4141470Egq4_mearly growth QTL 4 (mouse)Not determined1226863768500330Mouse
4142109W10q2_mweight 10 weeks QTL 2 (mouse)Not determined1226863768500330Mouse
4141582Lgaq1_mlate growth adjusted QTL 1 (mouse)Not determined1226863768500330Mouse
4142308W6q3_mweight 6 weeks QTL 3 (mouse)Not determined111226863768500330Mouse
4142216Lgq1_mlate growth QTL 1 (mouse)Not determined1226863768500330Mouse
4141966Tailq1_mtail length QTL 1 (mouse)Not determined1226863768500330Mouse
1357851Scfq3_msubcutaneous fat pad weight QTL 3 (mouse)Not determined111226863768500330Mouse
1357720Kidpq1_mkidney weight percentage QTL 1 (mouse)Not determined111226863768500330Mouse
1357437Epfq4_mepididymal fat pad weight QTL 4 (mouse)Not determined111226863768500330Mouse
1559002Lmrq4_mLeishmania major resistance QTL 4 (mouse)Not determined111226863769684947Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
1558945Orgwq8_morgan weight QTL 8 (mouse)Not determined111705617567078411Mouse
10053687Eae6_msusceptibility to experimental allergic encephalomyelitis 6 (mouse)Not determined111778196668500330Mouse
12801459Leuf1_mleukocyte filtration 1 (mouse)111857861652578716Mouse
12801460Intim2_mintima modifier 2 (mouse)111857861652578716Mouse
12801457Intmrm2_mintima/media ratio modifier 2 (mouse)111857861652578716Mouse
1300938Bulb3_mbulb size 3 (mouse)Not determined111857861652578716Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1912420496897826Mouse
1300579Thypr1_mthymocyte proliferative response 1 (mouse)Not determined111928257753282715Mouse
14746971Manh70_mmandible shape 70 (mouse)111990589053905890Mouse
4141398Tgq22_mtriglyceride QTL 22 (mouse)Not determined2116340655163406Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112180736495881231Mouse
1300607Tnbs2_mtri-nitrobenzene sulfonic acid susceptible 2 (mouse)Not determined112489805235126680Mouse
10044006Hbnr13_mHeligmosomoides bakeri nematode resistance 13 (mouse)Not determined112577262659772741Mouse
1302179Mndl2_mmandible length 2 (mouse)Not determined112590609727673304Mouse
1301814Bbaa7_mB.burgdorferi-associated arthritis 7 (mouse)Not determined112601178044264695Mouse

Markers in Region
AW554273  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381126,471,587 - 26,471,695UniSTSGRCm38
MGSCv371126,371,587 - 26,371,695UniSTSGRCm37
Celera1128,995,116 - 28,995,224UniSTS
Cytogenetic Map11A2-A3UniSTS
Cytogenetic Map11A3.3UniSTS
Whitehead/MRC_RH11425.79UniSTS
09.MMHAP36FLC3.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381126,575,734 - 26,575,928UniSTSGRCm38
MGSCv371126,475,734 - 26,475,928UniSTSGRCm37
Cytogenetic Map11A3.3UniSTS
Whitehead_YAC11 UniSTS
AI447698  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381126,471,540 - 26,471,695UniSTSGRCm38
MGSCv371126,371,540 - 26,371,695UniSTSGRCm37
Celera1128,995,116 - 28,995,271UniSTS
Cytogenetic Map11A2-A3UniSTS
Cytogenetic Map11A3.3UniSTS
Whitehead/MRC_RH11426.96UniSTS
Vrk2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11A3.3UniSTS
cM Map11 UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001252447 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_027260 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006514801 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011243748 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030246291 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC083815 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF513620 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK012664 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK053297 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK081198 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK089825 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK154485 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK186520 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL929272 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB852723 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC013520 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE984366 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466665 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSMUST00000078362   ⟹   ENSMUSP00000077471
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1126,421,404 - 26,543,920 (-)Ensembl
GRCm38.p6 Ensembl1126,471,404 - 26,593,920 (-)Ensembl
RefSeq Acc Id: ENSMUST00000109504   ⟹   ENSMUSP00000105130
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1126,421,322 - 26,541,729 (-)Ensembl
GRCm38.p6 Ensembl1126,471,322 - 26,591,729 (-)Ensembl
RefSeq Acc Id: ENSMUST00000124294
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1126,483,841 - 26,543,622 (-)Ensembl
GRCm38.p6 Ensembl1126,533,841 - 26,593,622 (-)Ensembl
RefSeq Acc Id: ENSMUST00000125545
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1126,533,296 - 26,543,603 (-)Ensembl
GRCm38.p6 Ensembl1126,583,296 - 26,593,603 (-)Ensembl
RefSeq Acc Id: ENSMUST00000133487
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1126,484,257 - 26,499,365 (-)Ensembl
GRCm38.p6 Ensembl1126,534,257 - 26,549,365 (-)Ensembl
RefSeq Acc Id: ENSMUST00000155728
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1126,495,395 - 26,543,923 (-)Ensembl
GRCm38.p6 Ensembl1126,545,395 - 26,593,923 (-)Ensembl
RefSeq Acc Id: ENSMUST00000156264   ⟹   ENSMUSP00000119928
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1126,497,848 - 26,543,999 (-)Ensembl
GRCm38.p6 Ensembl1126,547,848 - 26,593,999 (-)Ensembl
RefSeq Acc Id: NM_001252447   ⟹   NP_001239376
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391126,421,401 - 26,543,920 (-)NCBI
GRCm381126,471,401 - 26,593,920 (-)NCBI
Celera1128,995,024 - 28,995,410 (+)NCBI
Celera1137,253,847 - 37,372,542 (-)ENTREZGENE
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_027260   ⟹   NP_081536
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391126,421,401 - 26,543,920 (-)NCBI
GRCm381126,471,401 - 26,593,920 (-)NCBI
MGSCv371126,371,401 - 26,493,920 (-)RGD
Celera1137,253,847 - 37,372,542 (-)ENTREZGENE
Celera1128,995,024 - 28,995,410 (+)NCBI
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006514801   ⟹   XP_006514864
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391126,421,398 - 26,544,006 (-)NCBI
GRCm381126,471,409 - 26,594,012 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011243748   ⟹   XP_011242050
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391126,421,398 - 26,509,269 (-)NCBI
GRCm381126,471,398 - 26,559,263 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030246291   ⟹   XP_030102151
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391126,421,398 - 26,543,715 (-)NCBI
GRCm381126,471,398 - 26,593,715 (-)NCBI
Sequence:
RefSeq Acc Id: NP_081536   ⟸   NM_027260
- Peptide Label: isoform 1
- UniProtKB: Q91WS1 (UniProtKB/Swiss-Prot),   Q8CJ46 (UniProtKB/Swiss-Prot),   Q8BPU8 (UniProtKB/Swiss-Prot),   Q5SP88 (UniProtKB/Swiss-Prot),   Q5F1Z5 (UniProtKB/Swiss-Prot),   Q3U415 (UniProtKB/Swiss-Prot),   Q9CZF9 (UniProtKB/Swiss-Prot),   Q8BN21 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001239376   ⟸   NM_001252447
- Peptide Label: isoform 2
- UniProtKB: Q8BN21 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006514864   ⟸   XM_006514801
- Peptide Label: isoform X1
- UniProtKB: Q91WS1 (UniProtKB/Swiss-Prot),   Q8CJ46 (UniProtKB/Swiss-Prot),   Q8BPU8 (UniProtKB/Swiss-Prot),   Q5SP88 (UniProtKB/Swiss-Prot),   Q5F1Z5 (UniProtKB/Swiss-Prot),   Q3U415 (UniProtKB/Swiss-Prot),   Q9CZF9 (UniProtKB/Swiss-Prot),   Q8BN21 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011242050   ⟸   XM_011243748
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_030102151   ⟸   XM_030246291
- Peptide Label: isoform X2
RefSeq Acc Id: ENSMUSP00000105130   ⟸   ENSMUST00000109504
RefSeq Acc Id: ENSMUSP00000077471   ⟸   ENSMUST00000078362
RefSeq Acc Id: ENSMUSP00000119928   ⟸   ENSMUST00000156264
Protein Domains
Protein kinase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8BN21-F1-model_v2 AlphaFold Q8BN21 1-503 view protein structure

Promoters
RGD ID:6822447
Promoter ID:MM_KWN:6737
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_4Hour
Transcripts:ENSMUST00000109504
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361126,492,436 - 26,492,936 (-)MPROMDB
RGD ID:6822450
Promoter ID:MM_KWN:6739
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day3,   3T3L1_Day4,   MEF_B4,   MEF_B6
Transcripts:ENSMUST00000109505,   NM_027260,   OTTMUST00000018384,   OTTMUST00000018385,   OTTMUST00000018386,   OTTMUST00000018387
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361126,493,609 - 26,494,109 (-)MPROMDB
RGD ID:8674146
Promoter ID:EPDNEW_M15104
Type:initiation region
Name:Vrk2_2
Description:Mus musculus vaccinia related kinase 2 , transcript variant 2,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M15105  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381126,593,614 - 26,593,674EPDNEW
RGD ID:8674148
Promoter ID:EPDNEW_M15105
Type:initiation region
Name:Vrk2_1
Description:Mus musculus vaccinia related kinase 2 , transcript variant 2,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M15104  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381126,593,924 - 26,593,984EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1917172 AgrOrtholog
Ensembl Genes ENSMUSG00000064090 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000078362 ENTREZGENE
  ENSMUST00000078362.13 UniProtKB/Swiss-Prot
  ENSMUST00000109504 ENTREZGENE
  ENSMUST00000109504.8 UniProtKB/Swiss-Prot
  ENSMUST00000156264.2 UniProtKB/TrEMBL
Gene3D-CATH Transferase(Phosphotransferase) domain 1 UniProtKB/Swiss-Prot
InterPro Kinase-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/Swiss-Prot
  Ser/Thr_kinase_AS UniProtKB/Swiss-Prot
KEGG Report mmu:69922 UniProtKB/Swiss-Prot
MGD MGI:1917172 ENTREZGENE
NCBI Gene 69922 ENTREZGENE
PANTHER CASEIN KINASE-RELATED UniProtKB/Swiss-Prot
  SERINE/THREONINE-PROTEIN KINASE VRK2 UniProtKB/Swiss-Prot
Pfam Pkinase UniProtKB/Swiss-Prot
PhenoGen Vrk2 PhenoGen
PROSITE PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot
  PROTEIN_KINASE_ST UniProtKB/Swiss-Prot
SMART S_TKc UniProtKB/Swiss-Prot
Superfamily-SCOP SSF56112 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt Q3U415 ENTREZGENE
  Q5F1Z5 ENTREZGENE
  Q5SP86_MOUSE UniProtKB/TrEMBL
  Q5SP88 ENTREZGENE
  Q8BN21 ENTREZGENE
  Q8BPU8 ENTREZGENE
  Q8CJ46 ENTREZGENE
  Q91WS1 ENTREZGENE
  Q9CZF9 ENTREZGENE
  VRK2_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q3U415 UniProtKB/Swiss-Prot
  Q5F1Z5 UniProtKB/Swiss-Prot
  Q5SP88 UniProtKB/Swiss-Prot
  Q8BPU8 UniProtKB/Swiss-Prot
  Q8CJ46 UniProtKB/Swiss-Prot
  Q91WS1 UniProtKB/Swiss-Prot
  Q9CZF9 UniProtKB/Swiss-Prot