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Gene: Stap1 (signal transducing adaptor family member 1) Mus musculus
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Symbol: Stap1
Name: signal transducing adaptor family member 1
Description: ENCODES a protein that exhibits macrophage colony-stimulating factor receptor binding; receptor tyrosine kinase binding; SH3/SH2 adaptor activity; INVOLVED IN cellular response to lipopolysaccharide; negative regulation of macrophage chemotaxis; negative regulation of macrophage colony-stimulating factor signaling pathway; ASSOCIATED WITH familial hypercholesterolemia (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN cytoplasm (ortholog); intracellular membrane-bounded organelle (ortholog); mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; buta-1,3-diene
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI586015; BCR downstream signaling 1; Brdg1; signal-transducing adaptor protein 1; STAP-1; stem cell adaptor protein 1; stem cell adaptor protein STAP-1
Orthologs:
Homo sapiens (human) : STAP1 (signal transducing adaptor family member 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Stap1 (signal transducing adaptor family member 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Stap1 (signal transducing adaptor family member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : STAP1 (signal transducing adaptor family member 1)
Canis lupus familiaris (dog) : STAP1 (signal transducing adaptor family member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Stap1 (signal transducing adaptor family member 1)
Sus scrofa (pig) : STAP1 (signal transducing adaptor family member 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38586,071,584 - 86,106,125 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37586,500,853 - 86,533,018 (+)NCBIGRCm37mm9NCBIm37
MGSCv36587,146,389 - 87,178,554 (+)NCBImm8
Celera583,303,792 - 83,335,974 (+)NCBICelera
Cytogenetic Map5 E1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Stap1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1323119
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.