Stt3b (STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae)) - Rat Genome Database
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Gene: Stt3b (STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae)) Mus musculus
Analyze
Symbol: Stt3b
Name: STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae)
RGD ID: 1323089
MGI Page MGI
Description: Predicted to have dolichyl-diphosphooligosaccharide-protein glycotransferase activity. Predicted to be involved in cellular protein metabolic process; glycoprotein catabolic process; and response to unfolded protein. Predicted to localize to oligosaccharyltransferase complex. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Ix. Orthologous to human STT3B (STT3 oligosaccharyltransferase complex catalytic subunit B); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; N-linked glycan biosynthetic pathway; INTERACTS WITH 1,2-dichloroethane; 1,2-dimethylhydrazine; 2,3',4,4',5-Pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1300006C19Rik; B6dom1 antigen; dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B; oligosaccharyl transferase subunit STT3B; S; Simp; source of immunodominant MHC-associated peptides; STT3-B
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399115,071,538 - 115,139,536 (-)NCBIGRCm39mm39
GRCm389115,242,470 - 115,310,468 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9115,242,581 - 115,310,421 (-)EnsemblGRCm38mm10GRCm38
MGSCv379115,151,699 - 115,219,539 (-)NCBIGRCm37mm9NCBIm37
MGSCv369115,091,279 - 115,159,119 (-)NCBImm8
Celera9115,715,885 - 115,785,239 (-)NCBICelera
Cytogenetic Map9F3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10725249   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12439619   PMID:12466851   PMID:12477932   PMID:12887896   PMID:12904583   PMID:14610273  
PMID:15489334   PMID:15782199   PMID:16141072   PMID:16141073   PMID:20541250   PMID:21873635   PMID:25737280   PMID:28246125   PMID:29765039  


Genomics

Comparative Map Data
Stt3b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399115,071,538 - 115,139,536 (-)NCBIGRCm39mm39
GRCm389115,242,470 - 115,310,468 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9115,242,581 - 115,310,421 (-)EnsemblGRCm38mm10GRCm38
MGSCv379115,151,699 - 115,219,539 (-)NCBIGRCm37mm9NCBIm37
MGSCv369115,091,279 - 115,159,119 (-)NCBImm8
Celera9115,715,885 - 115,785,239 (-)NCBICelera
Cytogenetic Map9F3NCBI
STT3B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl331,532,638 - 31,637,616 (+)EnsemblGRCh38hg38GRCh38
GRCh38331,532,638 - 31,637,621 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37331,574,130 - 31,677,556 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36331,549,495 - 31,652,560 (+)NCBINCBI36hg18NCBI36
Celera331,512,441 - 31,615,151 (+)NCBI
Cytogenetic Map3p23NCBI
HuRef331,516,641 - 31,619,695 (+)NCBIHuRef
CHM1_1331,524,051 - 31,629,156 (+)NCBICHM1_1
Stt3b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.08123,303,910 - 123,370,729 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8123,293,057 - 123,371,257 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08122,604,518 - 122,668,754 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48119,680,704 - 119,747,784 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.18119,690,013 - 119,767,827 (-)NCBI
Celera8114,167,159 - 114,232,088 (-)NCBICelera
Cytogenetic Map8q32NCBI
Stt3b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543022,986,762 - 23,069,383 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543022,986,673 - 23,070,923 (+)NCBIChiLan1.0ChiLan1.0
STT3B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1331,771,271 - 31,873,389 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl331,771,265 - 31,873,381 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0331,454,297 - 31,557,189 (+)NCBIMhudiblu_PPA_v0panPan3
STT3B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2313,037,722 - 13,143,743 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12313,036,301 - 13,143,629 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Stt3b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_00493647322,197,625 - 22,288,941 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
STT3B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1317,534,171 - 17,635,035 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11317,532,341 - 17,635,039 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21319,678,088 - 19,778,904 (+)NCBISscrofa10.2Sscrofa10.2susScr3
STT3B
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl1576,060,406 - 76,165,468 (+)Ensembl
ChlSab1.11576,060,670 - 76,165,415 (+)NCBI
Stt3b
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247889,614,932 - 9,726,773 (+)NCBI

Position Markers
UniSTS:236273  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm389115,242,708 - 115,242,887UniSTSGRCm38
MGSCv379115,151,826 - 115,152,005UniSTSGRCm37
Celera9115,716,009 - 115,716,188UniSTS
Cytogenetic Map9F3UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4141833W10q13_mweight 10 weeks QTL 13 (mouse)Not determined63332429120362868Mouse
4141545Tailaq2_mtail length adjusted QTL 2 (mouse)Not determined63332429120362868Mouse
1357635Splq4_mspleen weight QTL 4 (mouse)Not determined963332429120362868Mouse
1301732Char1_mP. chabaudi malaria resistance QTL 1 (mouse)Not determined981798268115798392Mouse
1300884Sluc11_msusceptibility to lung cancer 11 (mouse)Not determined982910333116910428Mouse
1357461Idd2_minsulin dependent diabetes susceptibility 2 (mouse)Not determined982910333116910428Mouse
10766454Char10_mP. chabaudi malaria resistance QTL 10 (mouse)982910333116910428Mouse
1301487Nociq1_mnociceptive sensitivity inflammatory QTL 1 (mouse)Not determined984528818118528921Mouse
1300549Bbaa17_mB. burgdorferi-associated arthritis 17 (mouse)Not determined986230401120230530Mouse
1302103Dob2_mdietary obesity 2 (mouse)Not determined986239845120289624Mouse
11251716Siim2_mstress induced immobility 2 (mouse)986748483120748483Mouse
12880422V25Dq6_mvitamin D inactive form serum level QTL 6 (mouse)987800000121800000Mouse
10412242Alpq8_malcohol preference QTL 8 (mouse)Not determined989284925123284925Mouse
1301649Psl1_mpromotion susceptibility QTL 1 (mouse)Not determined989412277123412396Mouse
18182932Metl3_mmetabolite locus 3, N-acetylglutamate (mouse)989563342123563342Mouse
1357657Pymr_mPlasmodium yoelli malaria resistance (mouse)Not determined989977005118938021Mouse
12910770Splic1_mspleen iron content 1 (mouse)991413879124595110Mouse
12910772Lvic6_mliver iron content 6 (mouse)991413879124595110Mouse
12910773Splic3_mspleen iron content 3 (mouse)991413879124595110Mouse
1558767Skmw11_mskeletal muscle weight 11 (mouse)Not determined991641084124595110Mouse
13463474Hbbcq5_mhemoglobin concentration QTL 5 (mouse)991641084124595110Mouse
13463475Hctq7_mhematocrit QTL 7 (mouse)991641084124595110Mouse
13463477Rbc9_mred blood cell count 9 (mouse)991641084124595110Mouse
13463478Mchq18_mmean corpuscular hemoglobin QTL 18 (mouse)991641084124595110Mouse
13463480Mchcq2_mmean corpuscular hemoglobin concentration QTL 2 (mouse)991641084124595110Mouse
12904937Edlmmq9_mextensor digitorum longus muscle mass QTL 9 (mouse)991683173124595110Mouse
12904947Tammq7_mtibialis anterior muscle mass QTL 7 (mouse)991683173124595110Mouse
12904961Gmmq7_mgastrocnemius muscle mass QTL 7 (mouse)991683173124595110Mouse
1302001Bdln5_mbody length 5 (mouse)Not determined993762590124595110Mouse
1301484Bwq6_mbody weight (mouse)Not determined993762590124595110Mouse
14746992Manh67_mmandible shape 67 (mouse)994036768124595110Mouse
11537364Cnes5_mC. neoformans susceptibility locus 5 (mouse)996917590124595110Mouse
1301297Lcho1_mliver cholesterol 1 (mouse)Not determined9101060861124595110Mouse
1357627Tgq2_mtriglyceride QTL 2 (mouse)Not determined9102000187124595110Mouse
1357648Obq18_mobesity QTL 18 (mouse)Not determined9102000187124595110Mouse
1301789Pbwg4_mpostnatal body weight growth 4 (mouse)Not determined9103289445124595110Mouse
10412290Pvacm1l_mplasma vascular cell adhesion molecule 1 levels (mouse)Not determined9103289445124595110Mouse
12879896Berr3_mberghei resistance locus 3 (mouse)9103289445124595110Mouse
13515058Adip20d_madiposity 20d (mouse)9108915010118915010Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:342
Count of miRNA genes:283
Interacting mature miRNAs:306
Transcripts:ENSMUST00000035010
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_024222 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC162179 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI852345 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK012153 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK013164 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK017675 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK018758 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK145674 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK148065 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK152899 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK154979 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK170079 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK181242 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK181827 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK197225 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK205163 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK206118 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK206181 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK209560 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK213927 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK216679 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AX799084 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC003206 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC013054 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC052433 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466587 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000035010   ⟹   ENSMUSP00000035010
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9115,242,581 - 115,310,421 (-)Ensembl
RefSeq Acc Id: NM_024222   ⟹   NP_077184
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399115,071,538 - 115,139,536 (-)NCBI
GRCm389115,242,470 - 115,310,468 (-)NCBI
MGSCv379115,151,699 - 115,219,539 (-)RGD
Celera9115,715,885 - 115,785,239 (-)RGD
cM Map9 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_077184   ⟸   NM_024222
- UniProtKB: Q3TDQ1 (UniProtKB/Swiss-Prot),   A0A0R4J0D3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000035010   ⟸   ENSMUST00000035010

Promoters
RGD ID:6845224
Promoter ID:MM_KWN:59048
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000035010
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv369115,219,271 - 115,220,332 (-)MPROMDB
RGD ID:8671140
Promoter ID:EPDNEW_M13601
Type:initiation region
Name:Stt3b_2
Description:Mus musculus STT3, subunit of the oligosaccharyltransferase complex,homolog B , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M13602  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm389115,310,134 - 115,310,194EPDNEW
RGD ID:8671142
Promoter ID:EPDNEW_M13602
Type:initiation region
Name:Stt3b_1
Description:Mus musculus STT3, subunit of the oligosaccharyltransferase complex,homolog B , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M13601  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm389115,310,468 - 115,310,528EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1915542 AgrOrtholog
Ensembl Genes ENSMUSG00000032437 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000035010 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000035010 ENTREZGENE, UniProtKB/TrEMBL
InterPro Oligo_trans_STT3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:68292 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1915542 ENTREZGENE
NCBI Gene 68292 ENTREZGENE
Pfam STT3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Stt3b PhenoGen
UniGene Mm.296158 ENTREZGENE
UniProt A0A0R4J0D3 ENTREZGENE, UniProtKB/TrEMBL
  Q3TDQ1 ENTREZGENE
  Q8BGU3_MOUSE UniProtKB/TrEMBL
  STT3B_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q7TT24 UniProtKB/Swiss-Prot
  Q921E3 UniProtKB/Swiss-Prot
  Q99LL0 UniProtKB/Swiss-Prot
  Q9D2V2 UniProtKB/Swiss-Prot