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Gene: Fam89b (family with sequence similarity 89, member B) Mus musculus
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Symbol: Fam89b
Name: family with sequence similarity 89, member B
Description: Exhibits transcription corepressor binding activity. Involved in establishment of cell polarity; negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; and positive regulation of cell migration. Localizes to the cytoplasm and lamellipodium. Is expressed in several structures, including branchial arch; cranial ganglion; heart valve; medulla oblongata basal plate mantle layer; and sensory organ. Orthologous to human FAM89B (family with sequence similarity 89 member B); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1110021A21Rik; C184M protein; leucine repeat adapter protein 25; mammary tumor virus receptor 2; MMTV; MMTV receptor; Mtvr2
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl195,728,087 - 5,729,653 (-)Ensembl
GRCm38195,728,087 - 5,729,666 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37195,728,087 - 5,729,666 (-)NCBIGRCm37mm9NCBIm37
MGSCv36195,728,087 - 5,729,648 (-)NCBImm8
Celera195,598,137 - 5,599,716 (-)NCBICelera
Cytogenetic Map19 ANCBI
cM Map194.34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Fam89b
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1323059
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.