Rassf3 (Ras association (RalGDS/AF-6) domain family member 3) - Rat Genome Database

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Gene: Rassf3 (Ras association (RalGDS/AF-6) domain family member 3) Mus musculus
Analyze
Symbol: Rassf3
Name: Ras association (RalGDS/AF-6) domain family member 3
RGD ID: 1322919
MGI Page MGI
Description: Predicted to enable identical protein binding activity. Predicted to be involved in signal transduction. Predicted to be located in cytosol and plasma membrane. Predicted to be active in cytoplasm. Is expressed in embryo mesenchyme and tongue. Orthologous to human RASSF3 (Ras association domain family member 3); INTERACTS WITH 1,2-dichloroethane; 1,2-dimethylhydrazine; 2,2',4,4',5,5'-hexachlorobiphenyl.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: AW212023; AW322379; novel ras effector 1; Ras association (RalGDS/AF-6) domain family 3; Ras association domain family 3; ras association domain-containing protein 3
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910121,246,255 - 121,312,155 (-)NCBIGRCm39mm39
GRCm39 Ensembl10121,246,255 - 121,312,252 (-)Ensembl
GRCm3810121,410,350 - 121,476,250 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10121,410,350 - 121,476,347 (-)EnsemblGRCm38mm10GRCm38
MGSCv3710120,847,406 - 120,913,306 (-)NCBIGRCm37mm9NCBIm37
MGSCv3610120,813,410 - 120,879,310 (-)NCBImm8
Celera10123,791,135 - 123,860,972 (-)NCBICelera
Cytogenetic Map10D2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
1. MGD data from the GO Consortium
2. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11965544   PMID:12466851   PMID:12477932   PMID:14610273   PMID:15489334   PMID:15782199   PMID:16141072   PMID:16141073  
PMID:16602821   PMID:17967808   PMID:18799693   PMID:21267068   PMID:21873635  


Genomics

Comparative Map Data
Rassf3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910121,246,255 - 121,312,155 (-)NCBIGRCm39mm39
GRCm39 Ensembl10121,246,255 - 121,312,252 (-)Ensembl
GRCm3810121,410,350 - 121,476,250 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10121,410,350 - 121,476,347 (-)EnsemblGRCm38mm10GRCm38
MGSCv3710120,847,406 - 120,913,306 (-)NCBIGRCm37mm9NCBIm37
MGSCv3610120,813,410 - 120,879,310 (-)NCBImm8
Celera10123,791,135 - 123,860,972 (-)NCBICelera
Cytogenetic Map10D2NCBI
RASSF3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1264,507,001 - 64,697,564 (+)EnsemblGRCh38hg38GRCh38
GRCh381264,610,495 - 64,697,567 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371265,004,275 - 65,091,344 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361263,290,560 - 63,375,459 (+)NCBINCBI36hg18NCBI36
Build 341263,290,559 - 63,375,459NCBI
Celera1264,669,061 - 64,754,040 (+)NCBI
Cytogenetic Map12q14.2NCBI
HuRef1262,056,161 - 62,143,319 (+)NCBIHuRef
CHM1_11264,971,222 - 65,058,272 (+)NCBICHM1_1
Rassf3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2756,935,894 - 57,000,591 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl756,935,973 - 57,000,553 (-)Ensembl
Rnor_6.0763,513,825 - 63,578,499 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl763,513,910 - 63,578,490 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0763,737,721 - 63,801,766 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4760,719,224 - 60,783,887 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1760,742,406 - 60,804,477 (-)NCBI
Celera753,678,845 - 53,743,337 (-)NCBICelera
Cytogenetic Map7q22NCBI
Rassf3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545811,441,054 - 11,449,423 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545811,400,655 - 11,451,796 (+)NCBIChiLan1.0ChiLan1.0
RASSF3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11224,730,054 - 24,740,929 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1224,726,821 - 24,914,256 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01224,225,855 - 24,312,891 (-)NCBIMhudiblu_PPA_v0panPan3
RASSF3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1107,323,272 - 7,353,378 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl107,212,460 - 7,351,395 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha107,216,311 - 7,288,982 (+)NCBI
ROS_Cfam_1.0107,391,136 - 7,463,789 (+)NCBI
UMICH_Zoey_3.1107,256,809 - 7,329,001 (+)NCBI
UNSW_CanFamBas_1.0107,509,203 - 7,581,530 (+)NCBI
UU_Cfam_GSD_1.0107,639,690 - 7,712,109 (+)NCBI
Rassf3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494551,149,785 - 51,215,363 (-)NCBI
SpeTri2.0NW_0049365452,894,761 - 2,961,994 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RASSF3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl528,931,270 - 29,113,895 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1528,949,787 - 29,113,894 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
RASSF3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11160,289,751 - 60,374,220 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1160,289,680 - 60,375,600 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037185,399,844 - 185,485,784 (-)NCBIVero_WHO_p1.0
Rassf3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248023,683,105 - 3,749,173 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
AW212023  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3810121,410,490 - 121,410,612UniSTSGRCm38
MGSCv3710120,847,546 - 120,847,668UniSTSGRCm37
Celera10123,791,275 - 123,791,397UniSTS
Cytogenetic Map10D2UniSTS
Whitehead/MRC_RH101273.9UniSTS
Whitehead/MRC_RH101298.98UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1302067Scc9_mcolon tumor susceptibility 9 (mouse)Not determined1018383585125739363Mouse
27226772Tibl13_mtibia length 13, 10 week (mouse)1019000000129800000Mouse
27095911Pglq15_mpelvic girdle length QTL 15, 16 week (mouse)1039300000129800000Mouse
27226764Tibl19_mtibia length 19, 16 week (mouse)1039300000129800000Mouse
26884450Sklq15_mskull length QTL 15, 16 week (mouse)1059500000122500000Mouse
26884430Zlq5_mzygomatic length QTL 5, 10 week (mouse)1068000000125000000Mouse
26884405Huml2_mhumerus length 2, 5 week (mouse)1069900000132500000Mouse
11353832Pcholq4_mplasma cholesterol QTL 4 (mouse)1074151384125680038Mouse
11353843Gluq1_mblood glucose QTL 1 (mouse)1074151384125680038Mouse
1357779Tesq3_mtestis weight QTL 3 (mouse)Not determined1084243786122205623Mouse
4141479W10q8_mweight 10 weeks QTL 8 (mouse)Not determined84243786122205623Mouse
4141387Lgaq5_mlate growth adjusted QTL 5 (mouse)Not determined84243786122205623Mouse
4142496W6q8_mweight 6 weeks QTL 8 (mouse)Not determined84243786122205623Mouse
4142365Egq9_mearly growth QTL 9 (mouse)Not determined84243786122205623Mouse
1357594Estoq3_membryo survival total QTL 3 (mouse)Not determined1084243786122205623Mouse
1357622Espq3_membryo survival preimplantation QTL 3 (mouse)Not determined1084243786122205623Mouse
1300921Skl4_mskeletal size (tail length) 4 (mouse)Not determined1088252393122252530Mouse
4142386Tgq20_mtriglyceride QTL 20 (mouse)Not determined89000595123000595Mouse
1301758Fcsa3_mfemoral cross-sectional area 3 (mouse)Not determined1090091790124091893Mouse
11039516Ltpr5_mLeishmania tropica response 5 (mouse)1090671039125739363Mouse
4142461Bmd25_mbone mineral density 25 (mouse)Not determined1097381196130694993Mouse
1357544Vtbt10_mvertebral trabecular bone trait 10 (mouse)Not determined1097381196130694993Mouse
11533919Mvb4_mmodifier of vibrator 4 (mouse)397381196130694993Mouse
11533921Mvb2_mmodifier of vibrator 2 (mouse)1097381196130694993Mouse
12880413V125Dq9_mvitamin D active form serum level QTL 9 (mouse)1097700000130694993Mouse
4141402T2dm1sa_mtype 2 diabetes mellitus 1 in SMXA RI mice (mouse)Not determined97922739130694993Mouse
11040593Lmr5e_mleishmaniasis resistance 5e (mouse)1099384730130694993Mouse
11040595Lmr5c_mleishmaniasis resistance 5c (mouse)1099384730130694993Mouse
11040597Lmr5a_mleishmaniasis resistance 5a (mouse)1099384730130694993Mouse
1301968Estq4_mestradiol regulated response QTL 4 (mouse)Not determined10101150611130694993Mouse
1357744Cfbw4_mcystic fibrosis body weight 4 (mouse)Not determined10101150611130694993Mouse
1301901Im5_mimmunoregulatory 5 (mouse)Not determined10101661259130694993Mouse
4141361Cfmq3_mcystic fibrosis modifier QTL 3 (mouse)Not determined10101661259130694993Mouse
1300678Leg2_mlongevity extending gene 2 (mouse)Not determined10102671003130694993Mouse
27226725Tibw1_mtibia width 1, proximal, 5 week (mouse)10102900000123400000Mouse
1301895Exq1_mexploratory and excitability QTL 1 (mouse)Not determined10103011947130694993Mouse
14696727Kidrq2_mkidney weight, right QTL 2 (mouse)10103066603130694993Mouse
4141007Obrq10_mobesity resistance QTL 10 (mouse)Not determined103407822130694993Mouse
4141487Tgq21_mtriglyceride QTL 21 (mouse)Not determined104274116130694993Mouse
14746996Manh69_mmandible shape 69 (mouse)10104927733130694993Mouse
1357482Nhdlq4_mnon-HDL QTL 4 (mouse)Not determined10105205399130694993Mouse
1300679Nociq2_mnociceptive sensitivity inflammatory QTL 2 (mouse)Not determined10105205399130694993Mouse
1302200Sle12_msystematic lupus erythematosus susceptibility 12 (mouse)Not determined10105205399130694993Mouse
11040594Lmr5f_mleishmaniasis resistance 5f (mouse)10105343808130694993Mouse
11040596Lmr5d_mleishmaniasis resistance 5d (mouse)10105343808130694993Mouse
11040598Lmr5b_mleishmaniasis resistance 5b (mouse)10105343808130694993Mouse
4142089Obrq9_mobesity resistance QTL 9 (mouse)Not determined108680038130694993Mouse
4141153Ltgq2_mliver triglyceride QTL 2 (mouse)Not determined108680038130694993Mouse
11039496Ltpr5b_mLeishmania tropica response 5b (mouse)10108739225130694993Mouse
11041664Lmr25_mleishmaniasis resistance 25 (mouse)10108739225130694993Mouse
11049563Lmr25a_mleishmaniasis resistance 25a (mouse)10108739225130694993Mouse
11049570Lmr25b_mleishmaniasis resistance 25b (mouse)10108739225130694993Mouse
27226722Tibw7_mtibia width 7, proximal, 16 week (mouse)10108800000125600000Mouse
27095902Scvln11_msacral vertebrae length 2, 10 week (mouse)10110200000125600000Mouse
11353822Insq12_minsulin QTL 12 (mouse)10110617486125680038Mouse
11353823Homaq2_mhomeostatic model assessment QTL 2 (mouse)10110617486125680038Mouse
26884391Skwq11_mskull length QTL 11, 16 week (mouse)10113700000121800000Mouse
26884433Zlq2_mzygomatic length QTL 2, 5 week (mouse)10113700000125900000Mouse
26884383Bzwq3_mbi-zygomatic width QTL 3, 5 week (mouse)10114400000122900000Mouse
13506931Recrq11_mrecombination rate in male meiosis QTL 11 (mouse)10114500000123800000Mouse
26884377Skwq3_mskull length QTL 3, 5 week (mouse)10114800000122900000Mouse
1300796Lmr5_mleishmaniasis resistance 5 (mouse)Not determined10116384730122343923Mouse
27226742Metcl4_mmetatarsal-calcaneal length 4, 5 week (mouse)10118300000125600000Mouse
27226795Scvln17_msacral vertebrae length 2, 16 week (mouse)10118600000125000000Mouse
27226718Tibw3_mtibia width 3, proximal, 10 week (mouse)10119000000125600000Mouse
27095906Scvln5_msacral vertebrae length 2, 5 week (mouse)10119200000125000000Mouse
27226736Metcl15_mmetatarsal-calcaneal length 15, 16 week (mouse)10119200000125000000Mouse
27226747Metcl10_mmetatarsal-calcaneal length 10, 10 week (mouse)10119200000125000000Mouse
27095926Pglq4_mpelvic girdle length QTL 4, 5 week (mouse)10119200000125000000Mouse
26884443Sklq5_mskull length QTL 5, 5 week (mouse)10119200000125000000Mouse
27226784Tibl4_mtibia length 4, 5 week (mouse)10119200000125600000Mouse
27226791Feml8_mfemur length 8, 5 week (mouse)10119200000125900000Mouse
1301701Aggr1_maggression 1 (mouse)Not determined10119671003125739363Mouse
13801032Hwtf2_mheart weight by femur 2 (mouse)10120000000122000000Mouse
11353834Pcholq2_mplasma cholesterol QTL 2 (mouse)10120407822125680038Mouse
11353838Gluq3_mblood glucose QTL 3 (mouse)10120407822125680038Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:956
Count of miRNA genes:501
Interacting mature miRNAs:607
Transcripts:ENSMUST00000026902
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000026902   ⟹   ENSMUSP00000026902
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl10121,246,255 - 121,312,252 (-)Ensembl
GRCm38.p6 Ensembl10121,410,350 - 121,476,347 (-)Ensembl
RefSeq Acc Id: ENSMUST00000219500
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl10121,250,292 - 121,298,118 (-)Ensembl
GRCm38.p6 Ensembl10121,414,387 - 121,462,213 (-)Ensembl
RefSeq Acc Id: NM_138956   ⟹   NP_620406
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3910121,246,255 - 121,312,155 (-)NCBI
GRCm3810121,410,350 - 121,476,250 (-)ENTREZGENE
MGSCv3710120,847,406 - 120,913,306 (-)RGD
Celera10123,791,135 - 123,860,972 (-)RGD
cM Map10 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006513379   ⟹   XP_006513442
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3910121,246,255 - 121,298,253 (-)NCBI
GRCm3810121,410,350 - 121,462,208 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011243388   ⟹   XP_011241690
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3910121,246,255 - 121,271,694 (-)NCBI
GRCm3810121,410,350 - 121,435,789 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_620406   ⟸   NM_138956
- UniProtKB: Q99P51 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006513442   ⟸   XM_006513379
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_011241690   ⟸   XM_011243388
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSMUSP00000026902   ⟸   ENSMUST00000026902
Protein Domains
Ras-associating   SARAH

Promoters
RGD ID:6819791
Promoter ID:MM_KWN:5794
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   Spleen
Transcripts:ENSMUST00000026902
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3610120,912,896 - 120,913,807 (-)MPROMDB
RGD ID:8673400
Promoter ID:EPDNEW_M14731
Type:initiation region
Name:Rassf3_1
Description:Mus musculus Ras association (RalGDS/AF-6) domain family member3 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3810121,476,266 - 121,476,326EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2179722 AgrOrtholog
Ensembl Genes ENSMUSG00000025795 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000026902 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000026902 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro C-RASSF UniProtKB/Swiss-Prot
  RA_dom UniProtKB/Swiss-Prot
  RASSF3 UniProtKB/Swiss-Prot
  SARAH_dom UniProtKB/Swiss-Prot
  Ubiquitin-like_domsf UniProtKB/Swiss-Prot
KEGG Report mmu:192678 UniProtKB/Swiss-Prot
MGD MGI:2179722 ENTREZGENE
NCBI Gene 192678 ENTREZGENE
PANTHER PTHR22738 UniProtKB/Swiss-Prot
  PTHR22738:SF8 UniProtKB/Swiss-Prot
Pfam Nore1-SARAH UniProtKB/Swiss-Prot
  PF00788 UniProtKB/Swiss-Prot
PhenoGen Rassf3 PhenoGen
PROSITE PS50200 UniProtKB/Swiss-Prot
  SARAH UniProtKB/Swiss-Prot
SMART SM00314 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF54236 UniProtKB/Swiss-Prot
UniProt Q99P51 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q3TJ17 UniProtKB/Swiss-Prot