Rpia (ribose 5-phosphate isomerase A)

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Gene: Rpia (ribose 5-phosphate isomerase A) Mus musculus

Analyze

Symbol:

Rpia

Name:

ribose 5-phosphate isomerase A

RGD ID:

1322806

MGI Page

MGI

Description:

Enables ribose-5-phosphate isomerase activity. Predicted to be involved in D-ribose metabolic process; pentose-phosphate shunt, non-oxidative branch; and ribose phosphate metabolic process. Predicted to be active in intracellular membrane-bounded organelle. Is expressed in alimentary system; liver; lung; and respiratory system. Orthologous to human RPIA (ribose 5-phosphate isomerase A); PARTICIPATES IN pentose phosphate pathway; pentose phosphate pathway - non-oxidative phase; ribose 5-phosphate isomerase deficiency pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Also known as:

phosphoriboisomerase; ribose-5-phosphate isomerase; RPI

RGD Orthologs

Human

Rat

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	RPIA (ribose 5-phosphate isomerase A)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Rattus norvegicus (Norway rat):	Rpia (ribose 5-phosphate isomerase A)	HGNC	Treefam, EggNOG, OrthoMCL, NCBI, OMA, HomoloGene, Inparanoid, Panther, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):	Rpia (ribose 5-phosphate isomerase A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	RPIA (ribose 5-phosphate isomerase A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	RPIA (ribose 5-phosphate isomerase A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Rpia (ribose 5-phosphate isomerase A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	RPIA (ribose 5-phosphate isomerase A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	RPIA (ribose 5-phosphate isomerase A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Rpia (ribose 5-phosphate isomerase A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Rpia (ribose 5-phosphate isomerase A)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|TreeFam)
Homo sapiens (human):	RPIA (ribose 5-phosphate isomerase A)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|Roundup\|TreeFam)
Danio rerio (zebrafish):	rpia (ribose 5-phosphate isomerase A (ribose 5-phosphate epimerase))	Alliance	DIOPT (TreeFam\|ZFIN)
Saccharomyces cerevisiae (baker's yeast):	RKI1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|Roundup\|TreeFam)
Drosophila melanogaster (fruit fly):	Rpi	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|Roundup\|TreeFam)
Caenorhabditis elegans (roundworm):	rpia-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|Roundup)

Latest Assembly:

GRCm38 - Mouse Genome Assembly GRCm38

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	70,742,704 - 70,769,159 (-)	NCBI	GRCm39		mm39
GRCm39 Ensembl	6	70,742,704 - 70,769,216 (-)	Ensembl
GRCm38	6	70,765,720 - 70,792,175 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	70,765,720 - 70,792,232 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	70,715,714 - 70,742,169 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	6	70,695,280 - 70,721,734 (-)	NCBI			mm8
Celera	6	72,851,114 - 72,877,569 (-)	NCBI		Celera
Cytogenetic Map	6	C1	NCBI
cM Map	6	32.06	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Ribose 5-Phosphate Isomerase Deficiency (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (EXP)

17alpha-ethynylestradiol (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (ISO)

2,6-dinitrotoluene (ISO)

2-hydroxypropanoic acid (ISO)

2-methylcholine (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-diaminodiphenylmethane (EXP)

4-hydroxyphenyl retinamide (EXP)

acrylamide (ISO)

Aflatoxin B2 alpha (ISO)

aristolochic acid (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

caffeine (ISO)

calcitriol (ISO)

captan (EXP)

clofibrate (EXP)

cobalt dichloride (ISO)

dexamethasone (ISO)

dibutyl phthalate (ISO)

disodium selenite (ISO)

enzyme inhibitor (ISO)

ethanol (EXP)

fenvalerate (ISO)

finasteride (ISO)

folic acid (EXP)

gentamycin (ISO)

hydrogen cyanide (EXP)

hydrogen peroxide (ISO)

indometacin (ISO)

ivermectin (ISO)

methoxyacetic acid (ISO)

methyl methanesulfonate (ISO)

methylmercury chloride (ISO)

methylseleninic acid (ISO)

Monobutylphthalate (ISO)

p-toluidine (ISO)

perfluorooctane-1-sulfonic acid (EXP)

perfluorooctanoic acid (EXP)

phenobarbital (EXP,ISO)

pirinixic acid (EXP)

piroxicam (ISO)

potassium cyanide (EXP)

rac-lactic acid (ISO)

sodium arsenite (ISO)

sulindac (ISO)

sunitinib (ISO)

T-2 toxin (ISO)

tamoxifen (EXP)

temozolomide (ISO)

testosterone (ISO)

tetrachloromethane (EXP)

thapsigargin (EXP)

valproic acid (EXP,ISO)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

D-ribose metabolic process (IBA)

pentose-phosphate shunt (ISO)

pentose-phosphate shunt, non-oxidative branch (IBA,ISO)

ribose phosphate metabolic process (ISO)

Cellular Component

intracellular membrane-bounded organelle (IBA,ISO)

Molecular Function

carbohydrate binding (ISO)

identical protein binding (ISO)

isomerase activity (IEA)

monosaccharide binding (ISO)

protein binding (ISO)

ribose-5-phosphate isomerase activity (IBA,IDA,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

pentose phosphate pathway (IEA,ISO)

pentose phosphate pathway - non-oxidative phase (ISO)

ribose 5-phosphate isomerase deficiency pathway (ISO)

transaldolase deficiency pathway (ISO)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

decreased circulating calcium level (IEA)

decreased circulating glycerol level (IEA)

decreased circulating HDL cholesterol level (IEA)

preweaning lethality, complete penetrance (IEA)

References

References - curated


1.	Bublitz C and Steavenson S, J Biol Chem. 1988 Sep 15;263(26):12849-53.
2.	MGD data from the GO Consortium
3.	OMIM Disease Annotation Pipeline
4.	Pipeline to import KEGG annotations from KEGG into RGD
5.	Pipeline to import SMPDB annotations from SMPDB into RGD
6.	RGD automated import pipeline
7.	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8.	RGD automated import pipeline for gene-chemical interactions
9.	Veech RL Proc Natl Acad Sci U S A. 2003 May 13;100(10):5578-80. Epub 2003 Apr 29.

Additional References at PubMed

PMID:7758956	PMID:10349636	PMID:10725249	PMID:10922068	PMID:11042159	PMID:11076861	PMID:11217851	PMID:11489994	PMID:12466851	PMID:12477932	PMID:14681479	PMID:15489334
PMID:16141072	PMID:16141073	PMID:21267068	PMID:21677750	PMID:21873635	PMID:25429733	PMID:25505152	PMID:27215380	PMID:28245920	PMID:30550785	PMID:32325033	PMID:32968282

Genomics

Comparative Map Data

Rpia
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	70,742,704 - 70,769,159 (-)	NCBI	GRCm39		mm39
GRCm39 Ensembl	6	70,742,704 - 70,769,216 (-)	Ensembl
GRCm38	6	70,765,720 - 70,792,175 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	70,765,720 - 70,792,232 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	70,715,714 - 70,742,169 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	6	70,695,280 - 70,721,734 (-)	NCBI			mm8
Celera	6	72,851,114 - 72,877,569 (-)	NCBI		Celera
Cytogenetic Map	6	C1	NCBI
cM Map	6	32.06	NCBI

RPIA
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	2	88,691,673 - 88,750,929 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	2	88,691,673 - 88,750,929 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	2	88,991,191 - 89,050,446 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	88,772,291 - 88,831,567 (+)	NCBI	NCBI36		hg18	NCBI36
Build 34	2	88,830,465 - 88,889,707	NCBI
Celera	2	87,738,845 - 87,795,148 (-)	NCBI
Cytogenetic Map	2	p11.2	NCBI
HuRef	2	87,913,138 - 87,969,437 (+)	NCBI		HuRef
CHM1_1	2	88,920,696 - 88,980,049 (+)	NCBI		CHM1_1

Rpia
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	4	102,723,712 - 102,749,374 (-)	NCBI	mRatBN7.2
mRatBN7.2 Ensembl	4	102,723,712 - 102,749,355 (-)	Ensembl
Rnor_6.0	4	98,568,028 - 98,593,664 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	98,568,028 - 98,593,664 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	163,347,716 - 163,373,352 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	103,934,938 - 103,960,574 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	4	104,179,418 - 104,205,030 (-)	NCBI
Celera	4	91,899,774 - 91,925,410 (-)	NCBI		Celera
Cytogenetic Map	4	q31	NCBI

Rpia
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955424	106,978 - 135,612 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955424	107,297 - 135,577 (-)	NCBI	ChiLan1.0	ChiLan1.0

RPIA
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	2A	89,731,335 - 89,787,512 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2A	89,731,335 - 89,787,512 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	2A	87,823,741 - 87,880,061 (+)	NCBI	Mhudiblu_PPA_v0		panPan3

RPIA
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	17	37,640,740 - 37,671,308 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	17	37,491,846 - 37,522,341 (-)	NCBI
ROS_Cfam_1.0	17	38,539,274 - 38,569,568 (-)	NCBI
UMICH_Zoey_3.1	17	37,705,845 - 37,736,309 (-)	NCBI
UNSW_CanFamBas_1.0	17	37,742,287 - 37,772,838 (-)	NCBI
UU_Cfam_GSD_1.0	17	38,091,779 - 38,122,295 (-)	NCBI

Rpia
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024406292	78,496,444 - 78,523,704 (-)	NCBI
SpeTri2.0	NW_004936712	2,335,255 - 2,362,004 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RPIA
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	57,355,979 - 57,386,946 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	57,355,973 - 57,386,948 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	59,834,039 - 59,864,841 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RPIA
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	14	18,015,873 - 18,071,177 (-)	NCBI	ChlSab1.1		chlSab2
ChlSab1.1 Ensembl	14	18,016,740 - 18,071,013 (-)	Ensembl	ChlSab1.1		chlSab2
Vero_WHO_p1.0	NW_023666080	1,707,353 - 1,762,443 (+)	NCBI	Vero_WHO_p1.0

Rpia
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624749	15,783,289 - 15,810,795 (-)	NCBI	HetGla_female_1.0		hetGla2

Position Markers

AU017435

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	6	70,765,866 - 70,765,994	UniSTS	GRCm38
MGSCv37	6	70,715,860 - 70,715,988	UniSTS	GRCm37
Celera	6	72,851,260 - 72,851,388	UniSTS
Cytogenetic Map	6	C1	UniSTS
cM Map	6	30.0	UniSTS
Whitehead/MRC_RH	6	703.61	UniSTS

RPIA

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	6	70,773,494 - 70,774,275	UniSTS	GRCm38
MGSCv37	6	70,723,488 - 70,724,269	UniSTS	GRCm37
Celera	6	72,858,888 - 72,859,669	UniSTS
Cytogenetic Map	6	C1	UniSTS
cM Map	6	30.0	UniSTS

QTLs in Region (GRCm38)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
25440480	Moaq2_m	modifier of alien QTL 2 (mouse)					6	1	117500000	Mouse
26884414	Bzwq12_m	bi-zygomatic width QTL 12, 16 week (mouse)					6	3400000	139100000	Mouse
1300556	Cia6_m	collagen induced arthritis QTL 6 (mouse)			Not determined		6	4464884	87426034	Mouse
4142126	W3q3_m	weight 3 weeks QTL 3 (mouse)			Not determined			4503823	96656149	Mouse
4142361	W10q11_m	weight 10 weeks QTL 11 (mouse)			Not determined			4503823	96656149	Mouse
4142271	Egq8_m	early growth QTL 8 (mouse)			Not determined			4503823	96656149	Mouse
4142232	W6q4_m	weight 6 weeks QTL 4 (mouse)			Not determined			4503823	96656149	Mouse
26884441	Sklq3_m	skull length QTL 3, 5 week (mouse)					6	7600000	80600000	Mouse
1357442	Dbts1_m	diabetes 1 (mouse)			Not determined		6	18234148	73387692	Mouse
10412213	Sxbq2_m	SGC/Knj cross B6 QTL 2 (mouse)			Not determined		6	19912686	71322775	Mouse
13208564	Bmiq7_m	body mass index QTL 7 (mouse)					6	25000000	80000000	Mouse
4141782	Mrdq5_m	modifier of retinal degeneration QTL 5 (mouse)			Not determined			32850650	78238974	Mouse
14746995	Manh60_m	mandible shape 60 (mouse)					6	37225677	71225677	Mouse
1558984	Cplaq9_m	circadian period of locomotor activity 9 (mouse)			Not determined		6	38669625	92607450	Mouse
1301326	Trbv4c2_m	T cell receptor beta variable 4 (mouse)			Not determined		6	40891296	71379171	Mouse
12880424	V25Dq4_m	vitamin D inactive form serum level QTL 4 (mouse)					6	41600000	75600000	Mouse
1301266	Lmr4_m	leishmaniasis resistance 4 (mouse)			Not determined		6	42116373	76116515	Mouse
11040600	Lmr4c_m	leishmaniasis resistance 4c (mouse)					6	42116373	76116515	Mouse
11040601	Lmr4a_m	leishmaniasis resistance 4a (mouse)					6	42116373	76116515	Mouse
11533915	Mts4_m	mammary tumor susceptibility 4 (mouse)					6	42116373	76116515	Mouse
12910785	Pwgrq16_m	post-weaning growth rate QTL 16 (mouse)					6	43826813	77811523	Mouse
12910798	Pwgrq5_m	pre-weaning growth rate QTL 5 (mouse)					6	43826813	77811523	Mouse
12910802	Pwbwq12_m	post-weaning body weight QTL 12 (mouse)					6	43826813	77811523	Mouse
12910807	Pwbwq11_m	post-weaning body weight QTL 11 (mouse)					6	43826813	77811523	Mouse
12910809	Pwbwq10_m	post-weaning body weight QTL 10 (mouse)					6	43826813	77811523	Mouse
12910820	Ogrq3_m	overall growth rate QTL 3 (mouse)					6	43826813	77811523	Mouse
10043885	Cia6c_m	collagen induced arthritis QTL 6c (mouse)			Not determined		6	44465871	71119467	Mouse
1300618	Pgia19_m	proteoglycan induced arthritis 19 (mouse)			Not determined		6	45314059	87426034	Mouse
10412157	Fl1n_m	fatty liver 1 in NSY (mouse)			Not determined		6	45314059	128835032	Mouse
4142259	Tabw2_m	tally ho associated body weight 2 (mouse)			Not determined			46935985	136423692	Mouse
25314319	Histh6_m	histamine hypersensitivity 6 (mouse)					6	48720000	125360000	Mouse
25314320	Histh5_m	histamine hypersensitivity 5 (mouse)					6	48720000	148450000	Mouse
4140983	Srilp_m	sleep response to influenza, light phase (mouse)			Not determined			48726556	75447710	Mouse
1301962	Eila2_m	ethanol induced locomotor activity 2 (mouse)			Not determined		6	48726556	125356785	Mouse
1301254	Skts11_m	skin tumor susceptibility 11 (mouse)			Not determined		6	51179150	85179300	Mouse
1357683	Igf1sl1_m	IGF-1 serum levels 1 (mouse)			Not determined		6	52161713	116155267	Mouse
4141028	Mclr_m	methylcholanthrene lymphoma resistance (mouse)			Not determined			54373427	88379171	Mouse
15039373	Adip28_m	adiposity 28 (mouse)					6	56308211	90308211	Mouse
15039375	Bw41_m	body weight QTL 41 (mouse)					6	56308211	90308211	Mouse
1558977	Skmw10_m	skeletal muscle weight 10 (mouse)			Not determined		6	58447583	92447710	Mouse
10043972	Obq28_m	obesity QTL 28 (mouse)			Not determined		6	58540433	92540433	Mouse
1301740	Bwq2_m	body weight QTL 2 (mouse)			Not determined		6	60057680	94057799	Mouse
1301369	Im4_m	immunoregulatory 4 (mouse)			Not determined		6	63484738	97484905	Mouse
1300650	Bw18_m	body weight QTL 18 (mouse)			Not determined		6	66713869	100714031	Mouse
1301876	Bits2_m	bitterness sensitivity 2 (mouse)			Not determined		6	70425898	104426034	Mouse
1301813	Skl3_m	skeletal size (tail length) 3 (mouse)			Not determined		6	70425898	104426034	Mouse
1301034	Egrm2_m	early growth rate (mouse)			Not determined		6	70425898	104426034	Mouse

miRNA Target Status

Confirmed Target Of

miRNA Gene	Mature miRNA	Method Name	Result Type	Data Type	Support Type	PMID
Mirlet7b	mmu-let-7b-5p	Mirtarbase	external_info	Reporter assay	Non-Functional MTI	15131085

Predicted Target Of

	Summary Value
Count of predictions:	374
Count of miRNA genes:	289
Interacting mature miRNAs:	306
Transcripts:	ENSMUST00000066134, ENSMUST00000124633, ENSMUST00000129244
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_009075	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC153612	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC156398	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK137235	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK148291	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK166785	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC053526	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466523	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CO043650	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	L35034	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSMUST00000066134 ⟹ ENSMUSP00000064158

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	6	70,742,704 - 70,769,216 (-)	Ensembl
GRCm38.p6 Ensembl	6	70,765,720 - 70,792,232 (-)	Ensembl

RefSeq Acc Id:

ENSMUST00000124633

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	6	70,743,257 - 70,750,676 (-)	Ensembl
GRCm38.p6 Ensembl	6	70,766,273 - 70,773,692 (-)	Ensembl

RefSeq Acc Id:

ENSMUST00000129244

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	6	70,759,064 - 70,768,987 (-)	Ensembl
GRCm38.p6 Ensembl	6	70,782,080 - 70,792,003 (-)	Ensembl

RefSeq Acc Id:

NM_009075 ⟹ NP_033101

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	6	70,742,704 - 70,769,159 (-)	NCBI
GRCm38	6	70,765,720 - 70,792,175 (-)	ENTREZGENE
MGSCv37	6	70,715,714 - 70,742,169 (-)	RGD
Celera	6	72,851,114 - 72,877,569 (-)	RGD
cM Map	6		ENTREZGENE

Sequence:

show sequence

CGGAGAGGCTGGAGCGAGGCGGCGGGATGCAGCGCCCCGGGCCCTTCAGCACCCTCTACGGGCG
GGTCCTGGCCCCACTGCCCGGGCGGGCCGGGGGCGCGGCCTCGGGCGGGGGCGGGAACAACTGG
GGCCTCTCGGGTTCCCACGTGCAGTTGCCGGGGCGTGCACATTCGGAGACCCGCGGCGACAAGG
GAGGCTCGAGCGCGGGCGGCCCGGCCCCCTCCACGATGTCCAAGGCCGAGGAGGCTAAGAAGCT
GGCGAGCCACACGGCGGTGGAGAACCACGTGAAGAATAACCAAGTGCTGGGAATTGGAAGTGGT
TCTACAATTGTCCACGCTGTGCAGCGAATAGCTGAAAGAGTGAAGCAAGAGAATCTGGACCTCA
TCTGCATCCCCACATCTTTCCAGGCCAGGCAGCTTATCTTGCAGTATGGCTTAACCCTCAGTGA
CCTGGATCAACACCCAGAGATTGACCTTGCCATCGATGGTGCTGACGAAGTGGATGCTGAGCTC
AATCTCATCAAGGGTGGAGGAGGCTGCCTGACCCAGGAGAAGATCGTGGCTGGTTATGCAAGTC
GTTTCATTGTGATTGCTGATTTCAGGAAAGATTCAAAGAACCTCGGGGATCGGTGGCACAAGGG
GATTCCCATTGAAGTCATCCCAATGGCCTACGTCCCAGTGAGCCGGGCTGTGGCCCAGAAGTTT
GGGGGTGAGGTGGAACTTCGAATGGCTGTCAACAAGGCAGGGCCAGTGGTGACGGATAACGGGA
ATTTTATCCTGGACTGGAAGTTTGACCGGGTGCATAAATGGAGTGAAGTGAACACAGCTATCAA
AATGACTCCAGGCGTGGTGGACACAGGCCTTTTCATCAACATGGCAGAGAGAGTCTACTTTGGG
ATGCAGGATGGCTCAGTGAACGTGCGGGAGAAGCCCTTCTAGCCCTGAGAGGAGCAGGGTCCTC
ACCTTGAGTCTCCAGCCCAGGCACAGTGGACACGCCTCACCAGGAGCCTTTGCCTTAATGTACC
TTCATGTAGCTGTCCACAGTGCCAGAGTGGACGGCTGGCATGGGTGGGTGGGTGGGGGTAGTCA
AATCCAGTCTTATGAAGTATTGCTATGTGTCTTTTTAAAAAGAAATTTAAATATATATATATTT
TTACTATTAAAATATTCAGTTTTTTTATAAAATAGAACTTGATTTTATGTTTTATATGAAACCT
TACCAAAAACAAAAAAAACGTATAAATAAAAATAAGAGATCAGGACTGTCTCTGAAAGCTTTGA
CTGGACCTGCTGGTTAACCTTCTGAAGTTTTGGGTTTGCTGAGAAAGAACGTTTTTCTAAGCTG
GTGCAGGTCTCCTGATGCCTTATGGGAAACCTTGTTTACTGTTTACTTTCTTGTGACACTCTTG
TGTTTTCATTGTTACCACTCCCAAATCTTAGTTACATTTTAAGATCAGGTGTAGGGAATTGTGA
ATGGAGCAGCGGGGCTGTAGTGACGTGGGTACAAACTCCAGGTGAGCGAGAATGCACCTTCTCT
TGGATCCTGGCTTGGCTTTGCTCCTGCTGCTGTTGGAAGCCCCCGGTGGAAGCGGAAGCGCCTG
CTGGCAGTGCACAGCACTGTCTGAGATGTGAAGCACTTACTTTTTGTTGTTTGAATGTTTTCTT
TATGTGAATATCGTTTTGTTCCTCCGATGACCCTTGTATGATTTGGTATCAGAAGCTGTCACTT
TGTGCTGTTCGAAGGTTGAAATAAACGTTACTGTGCCATTTGGAAAAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_033101	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAC42060	(Get FASTA)	NCBI Sequence Viewer
	AAH53526	(Get FASTA)	NCBI Sequence Viewer
	BAE23281	(Get FASTA)	NCBI Sequence Viewer
	EDK98925	(Get FASTA)	NCBI Sequence Viewer
	P47968	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_033101 ⟸ NM_009075

- UniProtKB:

P47968 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MQRPGPFSTLYGRVLAPLPGRAGGAASGGGGNNWGLSGSHVQLPGRAHSETRGDKGGSSAGGPA
PSTMSKAEEAKKLASHTAVENHVKNNQVLGIGSGSTIVHAVQRIAERVKQENLDLICIPTSFQA
RQLILQYGLTLSDLDQHPEIDLAIDGADEVDAELNLIKGGGGCLTQEKIVAGYASRFIVIADFR
KDSKNLGDRWHKGIPIEVIPMAYVPVSRAVAQKFGGEVELRMAVNKAGPVVTDNGNFILDWKFD
RVHKWSEVNTAIKMTPGVVDTGLFINMAERVYFGMQDGSVNVREKPF

hide sequence

RefSeq Acc Id:

ENSMUSP00000064158 ⟸ ENSMUST00000066134

Promoters

RGD ID:

6839943

Promoter ID:

MM_KWN:46401

Type:

Non-CpG

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

Kidney

Transcripts:

OTTMUST00000054916

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	6	70,723,601 - 70,724,101 (-)	MPROMDB

RGD ID:

6839945

Promoter ID:

MM_KWN:46402

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

3T3L1_Day0, 3T3L1_Day1, 3T3L1_Day2, 3T3L1_Day3, 3T3L1_Day4, 3T3L1_Day6, BoneMarrow_0Hour, BoneMarrow_2Hour, BoneMarrow_4Hour, Brain, ES_Cell, Kidney, Liver, Lung, MEF_B4, MEF_B6, Spleen

Transcripts:

OTTMUST00000054914, UC009CFZ.1

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	6	70,741,856 - 70,742,427 (-)	MPROMDB

RGD ID:

6889940

Promoter ID:

EPDNEW_M8421

Type:

multiple initiation site

Name:

Rpia_1

Description:

Mus musculus ribose 5-phosphate isomerase A , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	6	70,792,174 - 70,792,234	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:103254	AgrOrtholog
Ensembl Genes	ENSMUSG00000053604	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein	ENSMUSP00000064158	ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSMUST00000066134	ENTREZGENE, UniProtKB/Swiss-Prot
InterPro	NagB/RpiA_transferase-like	UniProtKB/Swiss-Prot
	Ribose5P_isomerase_typA	UniProtKB/Swiss-Prot
	Ribose5P_isomerase_typA_subgr	UniProtKB/Swiss-Prot
KEGG Report	mmu:19895	UniProtKB/Swiss-Prot
MGD	MGI:103254	ENTREZGENE
NCBI Gene	19895	ENTREZGENE
PANTHER	PTHR11934	UniProtKB/Swiss-Prot
Pfam	Rib_5-P_isom_A	UniProtKB/Swiss-Prot
PhenoGen	Rpia	PhenoGen
Superfamily-SCOP	SSF100950	UniProtKB/Swiss-Prot
TIGRFAMs	rpiA	UniProtKB/Swiss-Prot
UniProt	P47968	ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary	Q3UVI8	UniProtKB/Swiss-Prot

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB

Imported Annotations - KEGG (archival)