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Gene: ITGB8 (integrin subunit beta 8) Homo sapiens
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Symbol: ITGB8
Name: integrin subunit beta 8
Description: Exhibits extracellular matrix protein binding activity. Involved in several processes, including positive regulation of angiogenesis; regulation of gene expression; and vasculogenesis. Localizes to the cell surface and integrin alphav-beta8 complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: integrin beta 8; integrin beta-8; integrin, beta 8
Orthologs:
Mus musculus (house mouse) : Itgb8 (integrin beta 8)  MGI  Alliance
Rattus norvegicus (Norway rat) : Itgb8 (integrin subunit beta 8)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Itgb8 (integrin subunit beta 8)
Pan paniscus (bonobo/pygmy chimpanzee) : ITGB8 (integrin subunit beta 8)
Canis lupus familiaris (dog) : ITGB8 (integrin subunit beta 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Itgb8 (integrin subunit beta 8)
Sus scrofa (pig) : ITGB8 (integrin subunit beta 8)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl720,330,702 - 20,415,754 (+)Ensembl
GRCh38720,329,819 - 20,415,754 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37720,370,345 - 20,455,382 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36720,337,250 - 20,421,907 (+)NCBINCBI36hg18NCBI36
Build 34720,143,985 - 20,223,659NCBI
Celera720,354,962 - 20,439,624 (+)NCBI
Cytogenetic Map7p21.1NCBI
HuRef720,258,397 - 20,343,469 (+)NCBIHuRef
CHM1_1720,370,975 - 20,455,655 (+)NCBICHM1_1
CRA_TCAGchr7v2720,422,044 - 20,506,723 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on ITGB8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1322799
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.