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Gene: YTHDF2 (YTH N6-methyladenosine RNA binding protein 2) Homo sapiens
Symbol: YTHDF2
Name: YTH N6-methyladenosine RNA binding protein 2
Description: Exhibits N6-methyladenosine-containing RNA binding activity. Involved in negative regulation of type I interferon-mediated signaling pathway and regulation of gene expression. Localizes to several cellular components, including P-body; centriolar satellite; and cytosol.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 9430020E02Rik; CAHL; CLL-associated antigen KW-14; HGRG8; high-glucose-regulated protein 8; NY-REN-2; renal carcinoma antigen NY-REN-2; yth domain family 2; YTH domain family protein 2; YTH domain family, member 2; YTH domain-containing family protein 2; YTH N(6)-methyladenosine RNA binding protein 2
Mus musculus (house mouse) : Ythdf2 (YTH N6-methyladenosine RNA binding protein 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ythdf2 (YTH N(6)-methyladenosine RNA binding protein 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ythdf2 (YTH N6-methyladenosine RNA binding protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : YTHDF2 (YTH N6-methyladenosine RNA binding protein 2)
Canis lupus familiaris (dog) : YTHDF2 (YTH N6-methyladenosine RNA binding protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ythdf2 (YTH N6-methyladenosine RNA binding protein 2)
Sus scrofa (pig) : YTHDF2 (YTH N6-methyladenosine RNA binding protein 2)
Chlorocebus sabaeus (African green monkey) : YTHDF2 (YTH N6-methyladenosine RNA binding protein 2)
Heterocephalus glaber (naked mole-rat) : Ythdf2 (YTH N6-methyladenosine RNA binding protein 2)
more info ...
Related Pseudogenes: YTHDF2P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl128,736,621 - 28,769,775 (+)EnsemblGRCh38hg38GRCh38
GRCh38128,736,621 - 28,769,775 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37129,063,133 - 29,096,287 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36128,935,723 - 28,968,874 (+)NCBINCBI36hg18NCBI36
Build 34128,884,098 - 28,916,902NCBI
Celera127,459,395 - 27,492,550 (+)NCBI
Cytogenetic Map1p35.3NCBI
HuRef127,315,797 - 27,348,923 (+)NCBIHuRef
CHM1_1129,178,454 - 29,211,612 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on YTHDF2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1322711
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.