Twsg1 (twisted gastrulation BMP signaling modulator 1) - Rat Genome Database

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Gene: Twsg1 (twisted gastrulation BMP signaling modulator 1) Mus musculus
Analyze
Symbol: Twsg1
Name: twisted gastrulation BMP signaling modulator 1
RGD ID: 1322558
MGI Page MGI
Description: Enables heparin binding activity. Acts upstream of or within several processes, including chondrocyte differentiation; negative regulation of osteoblast differentiation; and regulation of BMP signaling pathway. Located in extracellular space. Is expressed in several structures, including brain; genitourinary system; gut; sensory organ; and skeleton. Orthologous to human TWSG1 (twisted gastrulation BMP signaling modulator 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 1810013J15Rik; 9030422N06Rik; AW552143; D17Ertd403; D17Ertd403e; Ts; Tsg; Twg; twisted gastrulation homolog 1; twisted gastrulation protein homolog 1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391766,230,060 - 66,258,198 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1766,228,967 - 66,258,221 (-)EnsemblGRCm39 Ensembl
GRCm381765,923,065 - 65,951,187 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1765,921,972 - 65,951,226 (-)EnsemblGRCm38mm10GRCm38
MGSCv371766,272,405 - 66,300,527 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361765,822,609 - 65,850,673 (-)NCBIMGSCv36mm8
Celera1770,231,747 - 70,259,874 (-)NCBICelera
Cytogenetic Map17E1.1NCBI
cM Map1735.26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal B cell differentiation  (IAGP)
abnormal bone marrow cell morphology/development  (IAGP)
abnormal caudal vertebrae morphology  (IAGP)
abnormal cervical vertebrae morphology  (IAGP)
abnormal craniofacial development  (IAGP)
abnormal craniofacial morphology  (IAGP)
abnormal diencephalon morphology  (IAGP)
abnormal forebrain morphology  (IAGP)
abnormal foregut morphology  (IAGP)
abnormal frontonasal prominence morphology  (IAGP)
abnormal gait  (IAGP)
abnormal head morphology  (IAGP)
abnormal intervertebral disk development  (IAGP)
abnormal intervertebral disk morphology  (IAGP)
abnormal intramembranous bone ossification  (IAGP)
abnormal jaw morphology  (IAGP)
abnormal kidney development  (IAGP)
abnormal lateral ganglionic eminence morphology  (IAGP)
abnormal lens induction  (IAGP)
abnormal limb bone morphology  (IAGP)
abnormal long bone epiphyseal plate morphology  (IAGP)
abnormal long bone epiphyseal plate proliferative zone  (IAGP)
abnormal mandible morphology  (IAGP)
abnormal mouth morphology  (IAGP)
abnormal nose morphology  (IAGP)
abnormal oropharynx morphology  (IAGP)
abnormal retina morphology  (IAGP)
abnormal skeleton development  (IAGP)
abnormal skeleton morphology  (IAGP)
abnormal spleen development  (IAGP)
abnormal submandibular gland development  (IAGP)
abnormal tail morphology  (IAGP)
abnormal telencephalon development  (IAGP)
abnormal thoracic vertebrae morphology  (IAGP)
abnormal thymus development  (IAGP)
abnormal timing of postnatal eyelid opening  (IAGP)
abnormal vertebrae morphology  (IAGP)
abnormal vertebral arch development  (IAGP)
abnormal vertebral arch morphology  (IAGP)
abnormal vertebral column morphology  (IAGP)
abnormal vertebral lamina morphology  (IAGP)
abnormal vertebral spinous process morphology  (IAGP)
absent mandible  (IAGP)
absent nasal septum  (IAGP)
absent submandibular gland  (IAGP)
absent tongue  (IAGP)
agnathia  (IAGP)
anophthalmia  (IAGP)
cachexia  (IAGP)
cyclopia  (IAGP)
decreased body length  (IEA)
decreased body mass index  (IEA)
decreased body size  (IAGP)
decreased body weight  (IAGP)
decreased bone mineral content  (IAGP)
decreased bone mineral density of femur  (IAGP)
decreased bone mineral density of lumbar vertebrae  (IAGP)
decreased bone trabecula number  (IAGP)
decreased bone volume  (IAGP)
decreased caudal vertebrae number  (IAGP)
decreased circulating osteocalcin level  (IAGP)
decreased double-positive T cell number  (IAGP)
decreased erythrocyte cell number  (IAGP)
decreased immature B cell number  (IAGP)
decreased lymphocyte cell number  (IAGP)
decreased pre-B cell number  (IAGP)
decreased pro-B cell number  (IAGP)
decreased spleen white pulp amount  (IAGP)
decreased splenocyte number  (IAGP)
decreased thymocyte number  (IAGP)
decreased trabecular bone volume  (IAGP)
decreased width of hypertrophic chondrocyte zone  (IAGP)
delayed bone ossification  (IAGP)
delayed endochondral bone ossification  (IAGP)
disproportionate dwarf  (IAGP)
exencephaly  (IAGP)
fused first pharyngeal arch  (IAGP)
hindlimb paralysis  (IAGP)
holoprosencephaly  (IAGP)
increased granulocyte number  (IAGP)
increased monocyte cell number  (IAGP)
increased single-positive T cell number  (IAGP)
increased thymocyte apoptosis  (IAGP)
internal hemorrhage  (IAGP)
kinked tail  (IAGP)
lethality at weaning, incomplete penetrance  (IAGP)
lowered ear position  (IAGP)
microphthalmia  (IAGP)
microstomia  (IAGP)
neonatal lethality, incomplete penetrance  (IAGP)
oral atresia  (IAGP)
perinatal lethality  (IAGP)
perinatal lethality, incomplete penetrance  (IAGP)
persistence of notochord tissue  (IAGP)
postnatal growth retardation  (IAGP)
postnatal lethality, complete penetrance  (IAGP)
premature death  (IAGP)
prenatal lethality, incomplete penetrance  (IAGP)
pulmonary fibrosis  (IAGP)
short femur  (IAGP)
short tail  (IAGP)
single external naris  (IAGP)
small first pharyngeal arch  (IAGP)
subarachnoid hemorrhage  (IAGP)
thin neurocranium  (IAGP)
thrombocytopenia  (IAGP)
thymus atrophy  (IAGP)
tremors  (IAGP)
weight loss  (IEA)
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, etal., Development 2000 Apr;127(8):1737-49.
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. MGD IEA MGD IEA
5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6. Mouse MP Annotation Import Pipeline RGD automated import pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11260715   PMID:11420619   PMID:12119341   PMID:12421925   PMID:12477932   PMID:12665593   PMID:12904583  
PMID:14681194   PMID:15013800   PMID:15226823   PMID:15381701   PMID:15489334   PMID:15780974   PMID:15782199   PMID:15843411   PMID:15919755   PMID:16141072   PMID:16141073   PMID:16289463  
PMID:16905550   PMID:16934545   PMID:17967808   PMID:18644438   PMID:18789316   PMID:18799693   PMID:19389368   PMID:19414861   PMID:19419314   PMID:19538749   PMID:19914233   PMID:20493240  
PMID:21328453   PMID:21549111   PMID:21572028   PMID:21873635   PMID:21978004   PMID:23103586   PMID:24067355   PMID:24586548   PMID:25468951   PMID:25808976   PMID:26721501   PMID:29771958  
PMID:32325033  


Genomics

Comparative Map Data
Twsg1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391766,230,060 - 66,258,198 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1766,228,967 - 66,258,221 (-)EnsemblGRCm39 Ensembl
GRCm381765,923,065 - 65,951,187 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1765,921,972 - 65,951,226 (-)EnsemblGRCm38mm10GRCm38
MGSCv371766,272,405 - 66,300,527 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361765,822,609 - 65,850,673 (-)NCBIMGSCv36mm8
Celera1770,231,747 - 70,259,874 (-)NCBICelera
Cytogenetic Map17E1.1NCBI
cM Map1735.26NCBI
TWSG1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38189,334,773 - 9,402,420 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl189,334,767 - 9,402,420 (+)EnsemblGRCh38hg38GRCh38
GRCh37189,334,771 - 9,402,418 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36189,324,851 - 9,392,418 (+)NCBINCBI36Build 36hg18NCBI36
Build 34189,324,850 - 9,392,417NCBI
Celera189,219,304 - 9,286,615 (+)NCBICelera
Cytogenetic Map18p11.22NCBI
HuRef189,298,467 - 9,364,729 (+)NCBIHuRef
CHM1_1189,334,596 - 9,402,161 (+)NCBICHM1_1
T2T-CHM13v2.0189,497,987 - 9,565,608 (+)NCBIT2T-CHM13v2.0
Twsg1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.29105,533,116 - 105,567,525 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl9105,533,136 - 105,567,479 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx9113,944,806 - 113,973,639 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.09119,054,620 - 119,083,679 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.09117,410,654 - 117,439,487 (-)NCBIRnor_WKY
Rnor_6.09113,699,151 - 113,732,601 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl9113,699,170 - 113,732,622 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.09113,230,657 - 113,264,099 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.49104,694,731 - 104,729,090 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.19104,907,180 - 104,938,570 (-)NCBI
Celera9102,911,360 - 102,940,263 (-)NCBICelera
Cytogenetic Map9q37NCBI
Twsg1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554022,652,020 - 2,686,117 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554022,652,020 - 2,685,350 (-)NCBIChiLan1.0ChiLan1.0
TWSG1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1187,164,091 - 7,229,271 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl187,164,091 - 7,229,271 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0184,883,688 - 4,950,963 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
TWSG1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1775,337,347 - 75,397,485 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl775,335,235 - 75,398,325 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha774,725,544 - 74,790,454 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0775,385,087 - 75,451,743 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl775,385,019 - 75,452,636 (+)EnsemblROS_Cfam_1.0 Ensembl
UNSW_CanFamBas_1.0775,106,123 - 75,167,742 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0775,411,428 - 75,477,211 (+)NCBIUU_Cfam_GSD_1.0
Twsg1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049442,673,370 - 2,720,055 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366261,901,680 - 1,946,460 (-)EnsemblSpeTri2.0
SpeTri2.0NW_0049366261,901,686 - 1,946,554 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TWSG1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl698,625,505 - 98,678,258 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1698,629,116 - 98,678,322 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2691,965,863 - 92,015,046 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TWSG1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11868,225,350 - 68,289,458 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1868,225,343 - 68,290,969 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605043,175,298 - 43,240,621 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Twsg1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477018,047,810 - 18,081,761 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477018,047,790 - 18,081,559 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:857
Count of miRNA genes:555
Interacting mature miRNAs:646
Transcripts:ENSMUST00000024906
Prediction methods:Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301338Lmr1_mleishmaniasis resistance 1 (mouse)Not determined171008134086996400Mouse
4142150Stheal11_msoft tissue heal 11 (mouse)Not determined171228621183361768Mouse
1300885Mbis4_mMycobacterium bovis-induced systemic lupus erythematosus 4 (mouse)Not determined173517581770165926Mouse
10755514Amzn2_manatomical modifier of Zfp423 2 (mouse)173596629469966424Mouse
12904951Smmq2_msoleus muscle mass QTL 2 (mouse)173678974370789743Mouse
1300592Pcyts5_mplasmacytoma susceptibility 5 (mouse)Not determined173871288772712970Mouse
10755525Lymph2_mlymphocyte differential 2 (mouse)173880562672805626Mouse
10755534Lymph4_mlymphocyte differential 4 (mouse)173880562672805626Mouse
4141319Hmtb8_mhemostasis and thrombosis rebleeding time 8 (mouse)Not determined4053444774534623Mouse
15039324Nmrs48_mNAFLD-associated magnetic resonance shift 48 (mouse)174093918774939187Mouse
26884390Skwq9_mskull length QTL 9, 10 week (mouse)174371089167806995Mouse
26884428Cvht3_mcranial vault height 3, 5 week (mouse)174651092682407429Mouse
14700692Cihvtq1_mcoxsackieviral infection heart viral titre QTL 1 (mouse)175000702870006995Mouse
1357754Ahl3_mage related hearing loss 3 (mouse)Not determined175020395784204103Mouse
4141879Chlq9_mcirculating hormone level QTL 9 (mouse)Not determined175175842585758612Mouse
1357532Bmch7_mbone mechanical trait 7 (mouse)Not determined175175842585758612Mouse
1357447Heal13_mwound healing/regeneration 13 (mouse)Not determined175710765191107803Mouse
4141758Pstc5_mperiosteal circumference 5 (mouse)Not determined175710765191107803Mouse
4141011Bmd26_mbone mineral density 26 (mouse)Not determined175710765191107803Mouse
1300735Pgia20_mproteoglycan induced arthritis 20 (mouse)Not determined175710765191107803Mouse
12910536Nrq8a_mnoise-induced hearing loss resistant QTL 8a (mouse)175710765191107803Mouse
12910537Nrq8_mnoise-induced hearing loss resistant QTL 8 (mouse)175710765191107803Mouse
4142201Obrq15_mobesity resistance QTL 15 (mouse)Not determined5753444780885776Mouse
4142414Pregq4_mpregnancy QTL 4 (mouse)Not determined175753444793507179Mouse
4141040Hmtb9_mhemostasis and thrombosis rebleeding time 9 (mouse)Not determined5758908991589197Mouse
1301107Scc4_mcolon tumor susceptibility 4 (mouse)Not determined176230101095294699Mouse
11528551Sluc32_msusceptibility to lung cancer 32 (mouse)176230101095294699Mouse
1302017Aliq3_macute lung injury QTL 3 (mouse)Not determined176388554895294699Mouse
1301728Ffal1_mfree fatty acid level 1 (mouse)Not determined176521493895294699Mouse

Markers in Region
AW552143  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381765,923,531 - 65,923,623UniSTSGRCm38
MGSCv371766,272,871 - 66,272,963UniSTSGRCm37
Celera1770,232,213 - 70,232,305UniSTS
Cytogenetic Map17E1.1UniSTS
Whitehead/MRC_RH17746.55UniSTS
Twsg1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381765,926,085 - 65,926,282UniSTSGRCm38
MGSCv371766,275,425 - 66,275,622UniSTSGRCm37
Celera1770,234,767 - 70,234,964UniSTS
Cytogenetic Map17E1.1UniSTS
UniSTS:237682  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381765,925,353 - 65,925,643UniSTSGRCm38
MGSCv371766,274,693 - 66,274,983UniSTSGRCm37
Celera1770,234,035 - 70,234,325UniSTS
Cytogenetic Map17E1.1UniSTS
RH127159  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381765,924,189 - 65,924,433UniSTSGRCm38
MGSCv371766,273,529 - 66,273,773UniSTSGRCm37
Celera1770,232,871 - 70,233,115UniSTS
Cytogenetic Map17E1.1UniSTS
cM Map1738.0UniSTS
Whitehead/MRC_RH17739.81UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_023053 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036160742 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC121299 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF292033 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF295097 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ297390 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK007481 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK018524 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK033504 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK049646 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168547 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168633 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK190433 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK191126 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK191416 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK191846 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK191967 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK195642 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK197060 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK198217 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK200127 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK200138 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK203652 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK205101 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC004850 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CF727906 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466537 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ165542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CT025659 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000024906   ⟹   ENSMUSP00000024906
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1766,230,060 - 66,258,221 (-)Ensembl
GRCm38.p6 Ensembl1765,923,065 - 65,951,226 (-)Ensembl
RefSeq Acc Id: ENSMUST00000233580   ⟹   ENSMUSP00000156695
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1766,228,967 - 66,258,110 (-)Ensembl
GRCm38.p6 Ensembl1765,921,972 - 65,951,115 (-)Ensembl
RefSeq Acc Id: ENSMUST00000233663   ⟹   ENSMUSP00000156938
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1766,232,901 - 66,233,404 (-)Ensembl
GRCm38.p6 Ensembl1765,925,906 - 65,926,409 (-)Ensembl
RefSeq Acc Id: ENSMUST00000233855
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1766,236,685 - 66,258,132 (-)Ensembl
GRCm38.p6 Ensembl1765,929,690 - 65,951,137 (-)Ensembl
RefSeq Acc Id: NM_023053   ⟹   NP_075540
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391766,230,060 - 66,258,182 (-)NCBI
GRCm381765,923,065 - 65,951,187 (-)ENTREZGENE
MGSCv371766,272,405 - 66,300,527 (-)RGD
Celera1770,231,747 - 70,259,874 (-)RGD
cM Map17 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_036160742   ⟹   XP_036016635
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391766,230,060 - 66,258,198 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_075540   ⟸   NM_023053
- Peptide Label: precursor
- UniProtKB: Q9ERN7 (UniProtKB/Swiss-Prot),   Q9EP52 (UniProtKB/Swiss-Prot),   A0A8C6IH50 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000156695   ⟸   ENSMUST00000233580
RefSeq Acc Id: ENSMUSP00000156938   ⟸   ENSMUST00000233663
RefSeq Acc Id: ENSMUSP00000024906   ⟸   ENSMUST00000024906
RefSeq Acc Id: XP_036016635   ⟸   XM_036160742
- Peptide Label: isoform X1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9EP52-F1-model_v2 AlphaFold Q9EP52 1-222 view protein structure

Promoters
RGD ID:13676642
Promoter ID:EPDNEW_M22470
Type:initiation region
Name:Twsg1_1
Description:Mus musculus twisted gastrulation BMP signaling modulator 1 ,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381765,951,172 - 65,951,232EPDNEW
RGD ID:6828848
Promoter ID:MM_KWN:24017
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Liver,   Lung,   Spleen
Transcripts:NM_023053,   NM_023053_TWSG1,   UC008DGQ.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361766,300,191 - 66,300,691 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2137520 AgrOrtholog
Ensembl Genes ENSMUSG00000024098 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000024906 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000156695 UniProtKB/Swiss-Prot
  ENSMUSP00000156938.2 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000024906 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000233580 UniProtKB/Swiss-Prot
  ENSMUST00000233663.2 UniProtKB/TrEMBL
InterPro Tsg UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:65960 UniProtKB/Swiss-Prot
MGD MGI:2137520 ENTREZGENE
NCBI Gene 65960 ENTREZGENE
PANTHER PTHR12312 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Tsg UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Twsg1 PhenoGen
UniProt A0A3B2W899_MOUSE UniProtKB/TrEMBL
  A0A8C6IH50 ENTREZGENE
  Q9EP52 ENTREZGENE
  Q9ERN7 ENTREZGENE
  TWSG1_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q8CCB1 UniProtKB/Swiss-Prot
  Q8CEM6 UniProtKB/Swiss-Prot
  Q99K77 UniProtKB/Swiss-Prot
  Q9ERN7 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-14 Twsg1  twisted gastrulation BMP signaling modulator 1    twisted gastrulation homolog 1 (Drosophila)  Symbol and/or name change 5135510 APPROVED