Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 17beta-estradiol | decreases expression | EXP | | 6480464 | Estradiol results in decreased expression of PCDHB14 mRNA | CTD | PMID:31614463 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Pcdhb20 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of PCDHB20 mRNA | CTD | PMID:19465110 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Pcdhb20 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of PCDHB10 mRNA and Tetrachlorodibenzodioxin results in decreased expression of PCDHB14 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Pcdhb20 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of PCDHB20 mRNA | CTD | PMID:21570461 | 4,4'-sulfonyldiphenol | increases expression | ISO | Pcdhb20 (Mus musculus) | 6480464 | bisphenol S results in increased expression of PCDHB20 mRNA | CTD | PMID:30951980 | 4,4'-sulfonyldiphenol | decreases methylation | ISO | Pcdhb20 (Mus musculus) | 6480464 | bisphenol S results in decreased methylation of PCDHB14 exon | CTD | PMID:33297965 | 5-azacytidine | decreases expression | EXP | | 6480464 | Azacitidine results in decreased expression of PCDHB14 mRNA | CTD | PMID:20823114 | acetamide | increases expression | ISO | Pcdhb20 (Rattus norvegicus) | 6480464 | acetamide results in increased expression of PCDHB20 mRNA | CTD | PMID:31881176 | acrylamide | decreases expression | ISO | Pcdhb20 (Rattus norvegicus) | 6480464 | Acrylamide results in decreased expression of PCDHB20 mRNA | CTD | PMID:28959563 | aflatoxin B1 | affects expression | EXP | | 6480464 | Aflatoxin B1 affects the expression of PCDHB14 protein | CTD | PMID:20106945 | aflatoxin B1 | decreases methylation | EXP | | 6480464 | Aflatoxin B1 results in decreased methylation of PCDHB14 gene | CTD | PMID:27153756 | all-trans-retinoic acid | increases expression | EXP | | 6480464 | Tretinoin results in increased expression of PCDHB14 mRNA | CTD | PMID:23724009 | benzo[a]pyrene | affects methylation | EXP | | 6480464 | Benzo(a)pyrene affects the methylation of PCDHB14 exon and Benzo(a)pyrene affects the methylation of PCDHB14 promoter | CTD | PMID:27901495 | benzo[a]pyrene | increases methylation | EXP | | 6480464 | Benzo(a)pyrene results in increased methylation of PCDHB14 3' UTR | CTD | PMID:27901495 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of PCDHB14 mRNA | CTD | PMID:22576693 | bisphenol A | decreases expression | ISO | Pcdhb20 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of PCDHB20 mRNA | CTD | PMID:38074096 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of PCDHB14 mRNA | CTD | PMID:29275510 | bisphenol A | increases expression | ISO | Pcdhb20 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of PCDHB20 mRNA | CTD | PMID:30816183 and PMID:32528016 | bisphenol A | decreases expression | ISO | Pcdhb20 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of PCDHB10 mRNA and bisphenol A results in decreased expression of PCDHB14 mRNA | CTD | PMID:25181051 | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of PCDHB14 gene | CTD | PMID:22576693 | cerium trichloride | increases expression | ISO | Pcdhb20 (Mus musculus) | 6480464 | cerous chloride results in increased expression of PCDHB20 mRNA | CTD | PMID:23573234 | cyclosporin A | decreases expression | EXP | | 6480464 | Cyclosporine results in decreased expression of PCDHB14 mRNA | CTD | PMID:20106945 | dorsomorphin | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | doxorubicin | decreases expression | EXP | | 6480464 | Doxorubicin results in decreased expression of PCDHB14 mRNA | CTD | PMID:29803840 | endosulfan | decreases expression | ISO | Pcdhb20 (Rattus norvegicus) | 6480464 | Endosulfan results in decreased expression of PCDHB20 mRNA | CTD | PMID:29391264 | entinostat | decreases expression | EXP | | 6480464 | entinostat results in decreased expression of PCDHB14 mRNA | CTD | PMID:26272509 | entinostat | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PCDHB14 mRNA | CTD | PMID:27188386 | folic acid | decreases expression | ISO | Pcdhb20 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of PCDHB14 mRNA | CTD | PMID:25629700 | formaldehyde | increases expression | EXP | | 6480464 | Formaldehyde results in increased expression of PCDHB14 mRNA | CTD | PMID:23649840 | gentamycin | decreases expression | ISO | Pcdhb20 (Rattus norvegicus) | 6480464 | Gentamicins results in decreased expression of PCDHB10 mRNA | CTD | PMID:33387578 | glycidol | decreases expression | ISO | Pcdhb20 (Rattus norvegicus) | 6480464 | glycidol results in decreased expression of PCDHB10 mRNA | CTD | PMID:24915197 | lead diacetate | increases expression | ISO | Pcdhb20 (Mus musculus) | 6480464 | lead acetate results in increased expression of PCDHB14 mRNA | CTD | PMID:22609695 | lead diacetate | increases methylation | ISO | Pcdhb20 (Rattus norvegicus) | 6480464 | lead acetate results in increased methylation of PCDHB20 gene | CTD | PMID:29571894 | mancozeb | decreases expression | EXP | | 6480464 | mancozeb results in decreased expression of PCDHB14 mRNA | CTD | PMID:33396126 | maneb | multiple interactions | ISO | Pcdhb20 (Mus musculus) | 6480464 | [Maneb co-treated with Paraquat] results in decreased expression of PCDHB14 mRNA | CTD | PMID:36117858 | methylmercury chloride | decreases expression | EXP | | 6480464 | methylmercuric chloride results in decreased expression of PCDHB14 mRNA | CTD | PMID:28001369 | nitrofen | decreases expression | ISO | Pcdhb20 (Rattus norvegicus) | 6480464 | nitrofen results in decreased expression of PCDHB20 mRNA | CTD | PMID:26720608 | panobinostat | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PCDHB14 mRNA | CTD | PMID:27188386 | panobinostat | decreases expression | EXP | | 6480464 | panobinostat results in decreased expression of PCDHB14 mRNA | CTD | PMID:26272509 | paracetamol | decreases expression | ISO | Pcdhb20 (Rattus norvegicus) | 6480464 | Acetaminophen results in decreased expression of PCDHB10 mRNA more ... | CTD | PMID:33387578 | paraquat | multiple interactions | ISO | Pcdhb20 (Mus musculus) | 6480464 | [Maneb co-treated with Paraquat] results in decreased expression of PCDHB14 mRNA | CTD | PMID:36117858 | pirinixic acid | multiple interactions | EXP | | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of PCDHB14 mRNA | CTD | PMID:19710929 | potassium dichromate | increases expression | ISO | Pcdhb20 (Mus musculus) | 6480464 | Potassium Dichromate results in increased expression of PCDHB20 mRNA | CTD | PMID:23608068 | SB 431542 | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | sodium arsenite | decreases expression | EXP | | 6480464 | sodium arsenite results in decreased expression of PCDHB14 mRNA | CTD | PMID:34032870 | sodium arsenite | decreases expression | ISO | Pcdhb20 (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of PCDHB14 mRNA and sodium arsenite results in decreased expression of PCDHB20 mRNA | CTD | PMID:37682722 | sunitinib | decreases expression | EXP | | 6480464 | Sunitinib results in decreased expression of PCDHB14 mRNA | CTD | PMID:31533062 | trichloroethene | decreases expression | ISO | Pcdhb20 (Rattus norvegicus) | 6480464 | Trichloroethylene results in decreased expression of PCDHB10 mRNA more ... | CTD | PMID:33387578 | trichostatin A | decreases expression | EXP | | 6480464 | trichostatin A results in decreased expression of PCDHB14 mRNA | CTD | PMID:24935251 and PMID:26272509 | trichostatin A | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PCDHB14 mRNA | CTD | PMID:27188386 | triptonide | decreases expression | ISO | Pcdhb20 (Mus musculus) | 6480464 | triptonide results in decreased expression of PCDHB14 mRNA and triptonide results in decreased expression of PCDHB20 mRNA | CTD | PMID:33045310 | trovafloxacin | increases expression | ISO | Pcdhb20 (Mus musculus) | 6480464 | trovafloxacin results in increased expression of PCDHB14 mRNA | CTD | PMID:35537566 | valproic acid | decreases expression | EXP | | 6480464 | Valproic Acid results in decreased expression of PCDHB14 mRNA | CTD | PMID:26272509 and PMID:28001369 | valproic acid | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PCDHB14 mRNA | CTD | PMID:27188386 | vorinostat | decreases expression | EXP | | 6480464 | vorinostat results in decreased expression of PCDHB14 mRNA | CTD | PMID:27188386 | zinc sulfate | increases expression | EXP | | 6480464 | Zinc Sulfate results in increased expression of PCDHB14 mRNA | CTD | PMID:16330358 | |