Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Tmem259 | Mouse | 1,2-dimethylhydrazine | increases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of TMEM259 mRNA | CTD | PMID:22206623 | Tmem259 | Mouse | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of TMEM259 mRNA | CTD | PMID:22206623 | Tmem259 | Mouse | 17beta-estradiol | increases expression | ISO | TMEM259 (Homo sapiens) | 6480464 | Estradiol results in increased expression of TMEM259 mRNA | CTD | PMID:21632981 | Tmem259 | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of TMEM259 mRNA | CTD | PMID:21570461 and PMID:24680724 | Tmem259 | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Tmem259 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of TMEM259 mRNA | CTD | PMID:33387578 | Tmem259 | Mouse | 4,4'-sulfonyldiphenol | increases methylation | EXP | | 6480464 | bisphenol S results in increased methylation of TMEM259 exon | CTD | PMID:33297965 | Tmem259 | Mouse | 4,4'-sulfonyldiphenol | multiple interactions | ISO | Tmem259 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of TMEM259 mRNA | CTD | PMID:36041667 | Tmem259 | Mouse | 4,4'-sulfonyldiphenol | affects methylation | EXP | | 6480464 | bisphenol S affects the methylation of TMEM259 gene | CTD | PMID:31683443 | Tmem259 | Mouse | acrolein | multiple interactions | ISO | TMEM259 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of TMEM259 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of TMEM259 mRNA | CTD | PMID:32699268 | Tmem259 | Mouse | alpha-pinene | multiple interactions | ISO | TMEM259 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of TMEM259 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of TMEM259 mRNA | CTD | PMID:32699268 | Tmem259 | Mouse | amitrole | decreases expression | ISO | Tmem259 (Rattus norvegicus) | 6480464 | Amitrole results in decreased expression of TMEM259 mRNA | CTD | PMID:38685447 | Tmem259 | Mouse | aristolochic acid A | increases expression | ISO | TMEM259 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of TMEM259 mRNA | CTD | PMID:33212167 | Tmem259 | Mouse | atrazine | increases expression | ISO | TMEM259 (Homo sapiens) | 6480464 | Atrazine results in increased expression of TMEM259 mRNA | CTD | PMID:22378314 | Tmem259 | Mouse | benzo[a]pyrene | increases mutagenesis | ISO | TMEM259 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased mutagenesis of TMEM259 gene | CTD | PMID:25435355 | Tmem259 | Mouse | benzo[a]pyrene | increases methylation | ISO | TMEM259 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of TMEM259 3' UTR and Benzo(a)pyrene results in increased methylation of TMEM259 promoter | CTD | PMID:27901495 | Tmem259 | Mouse | benzo[a]pyrene | decreases expression | ISO | TMEM259 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of TMEM259 mRNA | CTD | PMID:20106945 | Tmem259 | Mouse | benzo[a]pyrene | multiple interactions | EXP | | 6480464 | AHR protein affects the reaction [Benzo(a)pyrene affects the expression of TMEM259 mRNA] | CTD | PMID:22228805 | Tmem259 | Mouse | beta-lapachone | decreases expression | ISO | TMEM259 (Homo sapiens) | 6480464 | beta-lapachone results in decreased expression of TMEM259 mRNA | CTD | PMID:38218311 | Tmem259 | Mouse | bisphenol A | affects expression | ISO | Tmem259 (Rattus norvegicus) | 6480464 | bisphenol A affects the expression of TMEM259 mRNA | CTD | PMID:25181051 | Tmem259 | Mouse | bisphenol A | multiple interactions | ISO | Tmem259 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of TMEM259 mRNA | CTD | PMID:36041667 | Tmem259 | Mouse | bisphenol A | decreases expression | ISO | Tmem259 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of TMEM259 mRNA | CTD | PMID:33296240 | Tmem259 | Mouse | bisphenol F | decreases expression | EXP | | 6480464 | bisphenol F results in decreased expression of TMEM259 mRNA | CTD | PMID:38685157 | Tmem259 | Mouse | bisphenol F | multiple interactions | ISO | Tmem259 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of TMEM259 mRNA | CTD | PMID:36041667 | Tmem259 | Mouse | butan-1-ol | multiple interactions | ISO | TMEM259 (Homo sapiens) | 6480464 | [[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of TMEM259 mRNA | CTD | PMID:29432896 | Tmem259 | Mouse | C60 fullerene | increases expression | ISO | Tmem259 (Rattus norvegicus) | 6480464 | fullerene C60 results in increased expression of TMEM259 mRNA | CTD | PMID:19167457 | Tmem259 | Mouse | cadmium atom | decreases expression | ISO | TMEM259 (Homo sapiens) | 6480464 | Cadmium results in decreased expression of TMEM259 mRNA | CTD | PMID:23369406 | Tmem259 | Mouse | chlorpyrifos | increases expression | EXP | | 6480464 | Chlorpyrifos results in increased expression of TMEM259 mRNA | CTD | PMID:37019170 | Tmem259 | Mouse | clofibrate | decreases expression | EXP | | 6480464 | Clofibrate results in decreased expression of TMEM259 mRNA | CTD | PMID:17585979 | Tmem259 | Mouse | cobalt dichloride | increases expression | ISO | TMEM259 (Homo sapiens) | 6480464 | cobaltous chloride results in increased expression of TMEM259 mRNA | CTD | PMID:19376846 | Tmem259 | Mouse | crocidolite asbestos | increases expression | EXP | | 6480464 | Asbestos and Crocidolite results in increased expression of TMEM259 mRNA | CTD | PMID:29279043 | Tmem259 | Mouse | cyclosporin A | decreases expression | ISO | TMEM259 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of TMEM259 mRNA | CTD | PMID:20106945 and PMID:21632981 | Tmem259 | Mouse | doxorubicin | decreases expression | ISO | TMEM259 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of TMEM259 mRNA | CTD | PMID:29803840 | Tmem259 | Mouse | ethanol | multiple interactions | ISO | TMEM259 (Homo sapiens) | 6480464 | [[Gasoline co-treated with Ethanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of TMEM259 mRNA | CTD | PMID:29432896 | Tmem259 | Mouse | fenthion | increases expression | EXP | | 6480464 | Fenthion results in increased expression of TMEM259 mRNA | CTD | PMID:34813904 | Tmem259 | Mouse | flutamide | increases expression | ISO | Tmem259 (Rattus norvegicus) | 6480464 | Flutamide results in increased expression of TMEM259 mRNA | CTD | PMID:24136188 | Tmem259 | Mouse | folic acid | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of TMEM259 mRNA | CTD | PMID:22206623 | Tmem259 | Mouse | folic acid | decreases expression | ISO | TMEM259 (Homo sapiens) | 6480464 | Folic Acid results in decreased expression of TMEM259 mRNA | CTD | PMID:21867686 | Tmem259 | Mouse | methamphetamine | increases expression | EXP | | 6480464 | Methamphetamine results in increased expression of TMEM259 mRNA | CTD | PMID:26307267 | Tmem259 | Mouse | methotrexate | affects response to substance | ISO | TMEM259 (Homo sapiens) | 6480464 | TMEM259 protein affects the susceptibility to Methotrexate | CTD | PMID:16217747 | Tmem259 | Mouse | nefazodone | increases expression | ISO | Tmem259 (Rattus norvegicus) | 6480464 | nefazodone results in increased expression of TMEM259 mRNA | CTD | PMID:24136188 | Tmem259 | Mouse | nimesulide | increases expression | ISO | Tmem259 (Rattus norvegicus) | 6480464 | nimesulide results in increased expression of TMEM259 mRNA | CTD | PMID:24136188 | Tmem259 | Mouse | ozone | multiple interactions | ISO | TMEM259 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of TMEM259 mRNA more ... | CTD | PMID:32699268 and PMID:35430440 | Tmem259 | Mouse | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of TMEM259 mRNA | CTD | PMID:17562736 | Tmem259 | Mouse | paracetamol | increases expression | ISO | Tmem259 (Rattus norvegicus) | 6480464 | Acetaminophen results in increased expression of TMEM259 mRNA | CTD | PMID:33387578 | Tmem259 | Mouse | rotenone | increases expression | ISO | Tmem259 (Rattus norvegicus) | 6480464 | Rotenone results in increased expression of TMEM259 mRNA | CTD | PMID:28374803 | Tmem259 | Mouse | sodium arsenite | increases expression | ISO | TMEM259 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of TMEM259 mRNA | CTD | PMID:38568856 | Tmem259 | Mouse | testosterone enanthate | affects expression | ISO | TMEM259 (Homo sapiens) | 6480464 | testosterone enanthate affects the expression of TMEM259 mRNA | CTD | PMID:17440010 | Tmem259 | Mouse | titanium dioxide | affects methylation | EXP | | 6480464 | titanium dioxide affects the methylation of TMEM259 gene | CTD | PMID:35295148 | Tmem259 | Mouse | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of TMEM259 mRNA | CTD | PMID:19448997 | Tmem259 | Mouse | trichostatin A | decreases expression | ISO | TMEM259 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of TMEM259 mRNA | CTD | PMID:28542535 | Tmem259 | Mouse | triphenyl phosphate | affects expression | ISO | TMEM259 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of TMEM259 mRNA | CTD | PMID:37042841 | Tmem259 | Mouse | valdecoxib | increases expression | ISO | Tmem259 (Rattus norvegicus) | 6480464 | valdecoxib results in increased expression of TMEM259 mRNA | CTD | PMID:24136188 | Tmem259 | Mouse | valproic acid | increases methylation | ISO | TMEM259 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of TMEM259 gene | CTD | PMID:29154799 | Tmem259 | Mouse | vinclozolin | decreases expression | ISO | Tmem259 (Rattus norvegicus) | 6480464 | vinclozolin results in decreased expression of TMEM259 mRNA | CTD | PMID:18042343 and PMID:23034163 | Tmem259 | Mouse | zoledronic acid | increases expression | ISO | TMEM259 (Homo sapiens) | 6480464 | zoledronic acid results in increased expression of TMEM259 mRNA | CTD | PMID:20977926 | |