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Gene: IMPDH1 (inosine monophosphate dehydrogenase 1) Homo sapiens
Symbol: IMPDH1
Name: inosine monophosphate dehydrogenase 1
Description: Exhibits DNA binding activity. Predicted to be involved in GTP biosynthetic process. Localizes to cytosol and nucleus. Implicated in Leber congenital amaurosis 11; retinitis pigmentosa; and retinitis pigmentosa 10.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DKFZp781N0678; IMP (inosine 5'-monophosphate) dehydrogenase 1; IMP (inosine monophosphate) dehydrogenase 1; IMP dehydrogenase 1; IMPD; IMPD 1; IMPD1; IMPDH 1; IMPDH-I; inosine-5'-monophosphate dehydrogenase 1; LCA11; retinitis pigmentosa 10 (autosomal dominant); RP10; sWSS2608
Mus musculus (house mouse) : Impdh1 (inosine monophosphate dehydrogenase 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Impdh1 (inosine monophosphate dehydrogenase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Impdh1 (inosine monophosphate dehydrogenase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : IMPDH1 (inosine monophosphate dehydrogenase 1)
Canis lupus familiaris (dog) : IMPDH1 (inosine monophosphate dehydrogenase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Impdh1 (inosine monophosphate dehydrogenase 1)
Sus scrofa (pig) : IMPDH1 (inosine monophosphate dehydrogenase 1)
Chlorocebus sabaeus (African green monkey) : IMPDH1 (inosine monophosphate dehydrogenase 1)
Heterocephalus glaber (naked mole-rat) : Impdh1 (inosine monophosphate dehydrogenase 1)
more info ...
Related Pseudogenes: IMPDH1P1   IMPDH1P10   IMPDH1P11   IMPDH1P2   IMPDH1P3   IMPDH1P4   IMPDH1P5   IMPDH1P6   IMPDH1P7   IMPDH1P8   IMPDH1P9  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl7128,392,277 - 128,410,252 (-)EnsemblGRCh38hg38GRCh38
GRCh387128,392,277 - 128,409,989 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh377128,032,331 - 128,050,045 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367127,819,567 - 127,837,272 (-)NCBINCBI36hg18NCBI36
Build 347127,626,282 - 127,643,992NCBI
Celera7122,835,429 - 122,853,135 (-)NCBI
Cytogenetic Map7q32.1NCBI
HuRef7122,393,708 - 122,411,003 (-)NCBIHuRef
CHM1_17127,965,901 - 127,983,587 (-)NCBICHM1_1
CRA_TCAGchr7v27127,415,442 - 127,433,147 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on IMPDH1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1322388
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.