Ooep (oocyte expressed protein) - Rat Genome Database

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Gene: Ooep (oocyte expressed protein) Mus musculus
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Symbol: Ooep
Name: oocyte expressed protein
RGD ID: 1322381
MGI Page MGI
Description: Enables RNA binding activity. Involved in several processes, including cytoskeleton organization; positive regulation of double-strand break repair via homologous recombination; and positive regulation of meiotic nuclear division. Acts upstream of or within several processes, including embryo implantation; establishment or maintenance of apical/basal cell polarity; and in utero embryonic development. Located in apical part of cell; cell cortex; and nucleus. Part of subcortical maternal complex. Is expressed in several structures, including early conceptus; nervous system; nose; ovary; and skeleton. Orthologous to human OOEP (oocyte expressed protein); INTERACTS WITH 1,2-dichloroethane; methylmercury chloride; aristolochic acid (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2410146L05Rik; factor located in oocytes permitting embryonic development; Flo; Floped; Moep; Moep19; oocyte and embryo specific protein; oocyte expressed protein homolog (dog); oocyte- and embryo-specific protein 19; oocyte-expressed protein homolog; riken cdna 2410146l05 gene; Sddr; STAT3 downstream gene and differentiation regulator
RGD Orthologs
Human
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39978,284,185 - 78,285,870 (-)NCBIGRCm39mm39
GRCm39 Ensembl978,283,391 - 78,286,007 (-)Ensembl
GRCm38978,376,903 - 78,378,588 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl978,376,109 - 78,378,725 (-)EnsemblGRCm38mm10GRCm38
MGSCv37978,224,710 - 78,226,395 (-)NCBIGRCm37mm9NCBIm37
MGSCv36978,163,089 - 78,164,272 (-)NCBImm8
Celera975,550,697 - 75,552,382 (-)NCBICelera
Cytogenetic Map9E1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
sialuria  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

Additional References at PubMed
PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:14610273   PMID:14681479   PMID:16141072   PMID:16141073   PMID:17567914  
PMID:18191828   PMID:18799693   PMID:18804437   PMID:19376971   PMID:20590823   PMID:21267068   PMID:21677750   PMID:21873635   PMID:23416452   PMID:23776005   PMID:25154302   PMID:25208553  
PMID:28992324   PMID:29125140   PMID:29955025   PMID:31118423   PMID:31330130   PMID:31575650   PMID:33351795   PMID:34174788  


Genomics

Comparative Map Data
Ooep
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39978,284,185 - 78,285,870 (-)NCBIGRCm39mm39
GRCm39 Ensembl978,283,391 - 78,286,007 (-)Ensembl
GRCm38978,376,903 - 78,378,588 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl978,376,109 - 78,378,725 (-)EnsemblGRCm38mm10GRCm38
MGSCv37978,224,710 - 78,226,395 (-)NCBIGRCm37mm9NCBIm37
MGSCv36978,163,089 - 78,164,272 (-)NCBImm8
Celera975,550,697 - 75,552,382 (-)NCBICelera
Cytogenetic Map9E1NCBI
OOEP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl673,368,555 - 73,395,133 (-)EnsemblGRCh38hg38GRCh38
GRCh38673,368,555 - 73,369,897 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37674,078,278 - 74,079,620 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36674,134,997 - 74,136,236 (-)NCBINCBI36hg18NCBI36
Celera674,472,826 - 74,474,063 (-)NCBI
Cytogenetic Map6q13NCBI
HuRef671,276,710 - 71,277,947 (-)NCBIHuRef
CHM1_1674,245,080 - 74,246,317 (-)NCBICHM1_1
Ooep
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2879,223,388 - 79,224,554 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl879,223,375 - 79,224,541 (-)Ensembl
Rnor_6.0885,719,447 - 85,720,806 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl885,719,496 - 85,720,790 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0885,272,439 - 85,273,601 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4883,342,296 - 83,343,423 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1883,361,357 - 83,362,485 (-)NCBI
Celera878,970,296 - 78,971,740 (-)NCBICelera
Cytogenetic Map8q31NCBI
OOEP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1674,484,758 - 74,485,995 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl674,484,764 - 74,511,331 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0671,195,619 - 71,197,040 (-)NCBIMhudiblu_PPA_v0panPan3
OOEP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11235,431,562 - 35,449,540 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1235,448,015 - 35,449,511 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1235,316,814 - 35,318,099 (-)NCBI
ROS_Cfam_1.01235,982,381 - 36,000,633 (-)NCBI
UMICH_Zoey_3.11235,539,947 - 35,541,240 (-)NCBI
UNSW_CanFamBas_1.01235,561,752 - 35,563,041 (-)NCBI
UU_Cfam_GSD_1.01235,687,471 - 35,688,765 (-)NCBI
LOC101968899
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494670,762,370 - 70,763,369 (-)NCBI
SpeTri2.0NW_0049373182,623 - 3,622 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
OOEP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl153,006,685 - 53,007,885 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1153,006,898 - 53,007,877 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2159,341,604 - 59,342,583 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103243900
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1171,775,192 - 1,777,214 (+)NCBI
ChlSab1.1 Ensembl171,775,955 - 1,776,982 (+)Ensembl
Vero_WHO_p1.0NW_0236660587,691,928 - 7,693,292 (+)NCBI

Position Markers
Ooep  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map9E1UniSTS
cM Map9 UniSTS
Ooep  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map9E1UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142042Alpq3_malcohol preference QTL 3 (mouse)Not determined93739490198819654Mouse
1301435Trigq1_mtriglyceride QTL 1 (mouse)Not determined94452089278520980Mouse
1300716Cd4ts4_mCD4 T cell subset 4 (mouse)Not determined94892377482923895Mouse
1300563Pgia5_mproteoglycan induced arthritis 5 (mouse)Not determined94892377482923895Mouse
4141224Dxmod_mdoxorubicin nephropathy modifier (mouse)Not determined49541121101528921Mouse
14746993Manh66_mmandible shape 66 (mouse)94990676683906766Mouse
1301184Bdln4_mbody length 4 (mouse)Not determined95024403884244166Mouse
1301241Renf1_mrenal failure 1 (mouse)Not determined95212317899910428Mouse
12790990Tgl7_mtriglyceride 7 (mouse)95465267888652678Mouse
10043877Adip21_madiposity 21 (mouse)Not determined95653182690531973Mouse
4141676Neogq1_mneonatal growth QTL 1 (mouse)Not determined95789776486239920Mouse
1301172Fembrs6_mfemur breaking strength 6 (mouse)Not determined95911710593117252Mouse
1301803Stheal9_msoft tissue heal 9 (mouse)Not determined95911710593117252Mouse
5491195Mobq8_mmultigenic obesity QTL 8 (mouse)Not determined95946266493462846Mouse
1300848Skull13_mskull morphology 13 (mouse)Not determined95946266493462846Mouse
1301456Adip5_madiposity 5 (mouse)Not determined95946266493462846Mouse
13207569Tcq13_mtotal cholesterol QTL 13 (mouse)959990000109260000Mouse
1301611Lrnx3_mlearning contextual 3 (mouse)Not determined96224248596242599Mouse
4141833W10q13_mweight 10 weeks QTL 13 (mouse)Not determined63332429120362868Mouse
4141545Tailaq2_mtail length adjusted QTL 2 (mouse)Not determined63332429120362868Mouse
1357635Splq4_mspleen weight QTL 4 (mouse)Not determined963332429120362868Mouse
11081165Psl6_mpromotion susceptibility QTL 6 (mouse)96513390995640755Mouse
1301290Smgd1_msubmucosal gland distribution 1 (mouse)Not determined96592377486695914Mouse
1301636Lith5_mlithogenic gene 5 (mouse)Not determined966207024100207122Mouse
10045638Heal29_mwound healing/regeneration 29 (mouse)Not determined967124167101124167Mouse
1357610Vtbt8_mvertebral trabecular bone trait 8 (mouse)Not determined968897510102897652Mouse
1301924Bmd10_mbone mineral density 10 (mouse)Not determined968897510102897652Mouse
1301302Pas4_mpulmonary adenoma susceptibility 4 (mouse)Not determined969239845103239920Mouse
10412174Habiir4_mhyperoxic acute lung injury imprinted region 4 (mouse)Not determined96936046598819654Mouse
1301621Hpic1_mhaloperidol-induced catalepsy 1 (mouse)Not determined969546513103546645Mouse
1301573Etohcta8_methanol conditioned taste aversion 8 (mouse)Not determined972977005106977152Mouse
10054068El8_mepilepsy 8 (mouse)Not determined972977005106977152Mouse
1301725Lifespan1_mlife span 1 (mouse)Not determined974368177108368325Mouse
1301914Ksc1_mkeratinocyte stem cell locus 1 (mouse)Not determined97550175580091050Mouse
1302065El1_mepilepsy 1 (mouse)Not determined975775364114474379Mouse
10054492El7_mepilepsy 7 (mouse)Not determined975775364114474379Mouse
1301869Tbbmd4_mtotal body bone mineral density 4 (mouse)Not determined976117105101528921Mouse
1301407Rapop2_mradiation-induced apoptosis 2 (mouse)Not determined976535936110536130Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:417
Count of miRNA genes:294
Interacting mature miRNAs:342
Transcripts:ENSMUST00000034900
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000034900   ⟹   ENSMUSP00000034900
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl978,283,391 - 78,286,007 (-)Ensembl
GRCm38.p6 Ensembl978,376,109 - 78,378,725 (-)Ensembl
RefSeq Acc Id: NM_026480   ⟹   NP_080756
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39978,284,185 - 78,285,870 (-)NCBI
GRCm38978,376,903 - 78,378,588 (-)ENTREZGENE
MGSCv37978,224,710 - 78,226,395 (-)RGD
Celera975,550,697 - 75,552,382 (-)RGD
cM Map9 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_080756   ⟸   NM_026480
- UniProtKB: Q9CWE6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000034900   ⟸   ENSMUST00000034900
Protein Domains
KH

Promoters
RGD ID:6844896
Promoter ID:MM_KWN:58158
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:ES_Cell
Transcripts:OTTMUST00000047136
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36978,226,326 - 78,226,826 (-)MPROMDB
RGD ID:8670270
Promoter ID:EPDNEW_M13166
Type:initiation region
Name:Ooep_1
Description:Mus musculus oocyte expressed protein , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38978,378,553 - 78,378,613EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1915218 AgrOrtholog
Ensembl Genes ENSMUSG00000032346 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000034900 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000034900 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.1370.10 UniProtKB/Swiss-Prot
InterPro KH_dom_type_1_sf UniProtKB/Swiss-Prot
  MOEP19_KH-like UniProtKB/Swiss-Prot
  OOEP UniProtKB/Swiss-Prot
KEGG Report mmu:67968 UniProtKB/Swiss-Prot
MGD MGI:1915218 ENTREZGENE
NCBI Gene 67968 ENTREZGENE
PANTHER PTHR19447:SF14 UniProtKB/Swiss-Prot
Pfam MOEP19 UniProtKB/Swiss-Prot
PhenoGen Ooep PhenoGen
UniProt OOEP_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-03-20 Ooep  oocyte expressed protein  Ooep  oocyte expressed protein homolog (dog)  Symbol and/or name change 5135510 APPROVED