Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | decreases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of DPP8 mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DPP8 mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | affects expression | EXP | | 6480464 | Ethinyl Estradiol affects the expression of DPP8 mRNA | CTD | PMID:17555576 | 17alpha-ethynylestradiol | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of DPP8 mRNA | CTD | PMID:17942748 | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of DPP8 mRNA | CTD | PMID:17942748 | 2,2',5,5'-tetrachlorobiphenyl | decreases expression | ISO | Dpp8 (Rattus norvegicus) | 6480464 | 2 more ... | CTD | PMID:23829299 | 2,3',4,4',5-Pentachlorobiphenyl | decreases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:31388691 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of DPP8 mRNA and Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to DPP8 promoter] | CTD | PMID:17942748 and PMID:19654925 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Dpp8 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of DPP8 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of DPP8 mRNA | CTD | PMID:21570461 | 2,6-dinitrotoluene | affects expression | ISO | Dpp8 (Rattus norvegicus) | 6480464 | 2 and 6-dinitrotoluene affects the expression of DPP8 mRNA | CTD | PMID:21346803 | 2-hydroxypropanoic acid | decreases expression | ISO | DPP8 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of DPP8 mRNA | CTD | PMID:30851411 | acrolein | multiple interactions | ISO | DPP8 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of DPP8 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of DPP8 mRNA | CTD | PMID:32699268 | aflatoxin B1 | decreases methylation | ISO | DPP8 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of DPP8 intron | CTD | PMID:30157460 | Aflatoxin B2 alpha | decreases methylation | ISO | DPP8 (Homo sapiens) | 6480464 | aflatoxin B2 results in decreased methylation of DPP8 intron | CTD | PMID:30157460 | alpha-pinene | multiple interactions | ISO | DPP8 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of DPP8 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of DPP8 mRNA | CTD | PMID:32699268 | antirheumatic drug | increases expression | ISO | DPP8 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of DPP8 mRNA | CTD | PMID:24449571 | arsane | affects methylation | ISO | DPP8 (Homo sapiens) | 6480464 | Arsenic affects the methylation of DPP8 gene | CTD | PMID:25304211 | arsenic atom | affects methylation | ISO | DPP8 (Homo sapiens) | 6480464 | Arsenic affects the methylation of DPP8 gene | CTD | PMID:25304211 | arsenite(3-) | multiple interactions | ISO | DPP8 (Homo sapiens) | 6480464 | arsenite inhibits the reaction [G3BP1 protein binds to DPP8 mRNA] | CTD | PMID:32406909 | benzo[a]pyrene | affects methylation | ISO | DPP8 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of DPP8 intron | CTD | PMID:30157460 | benzo[a]pyrene diol epoxide I | decreases expression | ISO | DPP8 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:19150397 | benzo[e]pyrene | decreases methylation | ISO | DPP8 (Homo sapiens) | 6480464 | benzo(e)pyrene results in decreased methylation of DPP8 intron | CTD | PMID:30157460 | bisphenol A | affects expression | ISO | Dpp8 (Rattus norvegicus) | 6480464 | bisphenol A affects the expression of DPP8 mRNA | CTD | PMID:25181051 | bisphenol A | increases expression | ISO | Dpp8 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of DPP8 mRNA | CTD | PMID:30816183 and PMID:32528016 | bisphenol A | increases methylation | ISO | Dpp8 (Rattus norvegicus) | 6480464 | bisphenol A results in increased methylation of DPP8 gene | CTD | PMID:28505145 | Brodifacoum | increases expression | ISO | Dpp8 (Rattus norvegicus) | 6480464 | bromfenacoum results in increased expression of DPP8 protein | CTD | PMID:28903499 | cadmium dichloride | decreases expression | ISO | Dpp8 (Rattus norvegicus) | 6480464 | Cadmium Chloride results in decreased expression of DPP8 mRNA | CTD | PMID:33453195 | cerium trichloride | increases expression | EXP | | 6480464 | cerous chloride results in increased expression of DPP8 mRNA | CTD | PMID:23573234 | CGP 52608 | multiple interactions | ISO | DPP8 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to DPP8 gene] | CTD | PMID:28238834 | chlorpyrifos | decreases expression | EXP | | 6480464 | Chlorpyrifos results in decreased expression of DPP8 mRNA | CTD | PMID:37019170 | copper(II) sulfate | decreases expression | ISO | DPP8 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of DPP8 mRNA | CTD | PMID:19549813 | crocidolite asbestos | decreases expression | EXP | | 6480464 | Asbestos and Crocidolite results in decreased expression of DPP8 mRNA | CTD | PMID:29279043 | cyclosporin A | decreases expression | ISO | DPP8 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of DPP8 mRNA | CTD | PMID:25562108 | ethanol | affects splicing | EXP | | 6480464 | Ethanol affects the splicing of DPP8 mRNA | CTD | PMID:30319688 | fenthion | decreases expression | EXP | | 6480464 | Fenthion results in decreased expression of DPP8 mRNA | CTD | PMID:34813904 | flutamide | decreases expression | ISO | Dpp8 (Rattus norvegicus) | 6480464 | Flutamide results in decreased expression of DPP8 mRNA | CTD | PMID:24136188 | folic acid | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DPP8 mRNA | CTD | PMID:22206623 | folic acid | decreases expression | EXP | | 6480464 | Folic Acid results in decreased expression of DPP8 mRNA | CTD | PMID:25629700 | formaldehyde | decreases expression | ISO | DPP8 (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of DPP8 mRNA | CTD | PMID:23649840 | gentamycin | decreases expression | ISO | Dpp8 (Rattus norvegicus) | 6480464 | Gentamicins results in decreased expression of DPP8 mRNA | CTD | PMID:33387578 | ivermectin | decreases expression | ISO | DPP8 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of DPP8 protein | CTD | PMID:32959892 | methapyrilene | decreases expression | ISO | Dpp8 (Rattus norvegicus) | 6480464 | Methapyrilene results in decreased expression of DPP8 mRNA | CTD | PMID:30467583 | methapyrilene | decreases methylation | ISO | DPP8 (Homo sapiens) | 6480464 | Methapyrilene results in decreased methylation of DPP8 intron | CTD | PMID:30157460 | methidathion | affects expression | EXP | | 6480464 | methidathion affects the expression of DPP8 mRNA | CTD | PMID:34813904 | methyl methanesulfonate | increases expression | ISO | DPP8 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of DPP8 mRNA | CTD | PMID:23649840 | methylmercury chloride | increases expression | ISO | DPP8 (Homo sapiens) | 6480464 | methylmercuric chloride results in increased expression of DPP8 mRNA | CTD | PMID:28001369 | miconazole | decreases expression | EXP | | 6480464 | Miconazole results in decreased expression of DPP8 mRNA | CTD | PMID:27462272 | ozone | multiple interactions | ISO | DPP8 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of DPP8 mRNA more ... | CTD | PMID:32699268 | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of DPP8 mRNA | CTD | PMID:17562736 | phenobarbital | increases expression | ISO | Dpp8 (Rattus norvegicus) | 6480464 | Phenobarbital results in increased expression of DPP8 mRNA | CTD | PMID:12082028 | phenobarbital | increases expression | EXP | | 6480464 | Phenobarbital results in increased expression of DPP8 mRNA | CTD | PMID:19270015 | pirinixic acid | increases expression | EXP | | 6480464 | pirinixic acid results in increased expression of DPP8 mRNA | CTD | PMID:18301758 and PMID:23811191 | rac-lactic acid | decreases expression | ISO | DPP8 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of DPP8 mRNA | CTD | PMID:30851411 | resveratrol | multiple interactions | ISO | DPP8 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of DPP8 mRNA | CTD | PMID:23557933 | sodium arsenate | increases expression | EXP | | 6480464 | sodium arsenate results in increased expression of DPP8 mRNA | CTD | PMID:21795629 | sodium fluoride | increases expression | EXP | | 6480464 | Sodium Fluoride results in increased expression of DPP8 mRNA | CTD | PMID:27862939 | tetrachloromethane | decreases expression | ISO | Dpp8 (Rattus norvegicus) | 6480464 | Carbon Tetrachloride results in decreased expression of DPP8 mRNA | CTD | PMID:31150632 | thioacetamide | increases expression | ISO | Dpp8 (Rattus norvegicus) | 6480464 | Thioacetamide results in increased expression of DPP8 mRNA | CTD | PMID:34492290 | valproic acid | increases expression | ISO | DPP8 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of DPP8 mRNA | CTD | PMID:23179753 | valproic acid | affects splicing | ISO | Dpp8 (Rattus norvegicus) | 6480464 | Valproic Acid affects the splicing of DPP8 mRNA | CTD | PMID:29427782 | valproic acid | affects expression | ISO | DPP8 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of DPP8 mRNA | CTD | PMID:25979313 | vildagliptin | decreases activity | ISO | DPP8 (Homo sapiens) | 6480464 | vildagliptin results in decreased activity of DPP8 protein | CTD | PMID:17287297 | zinc atom | multiple interactions | ISO | DPP8 (Homo sapiens) | 6480464 | [PCI 5002 co-treated with Zinc] results in increased expression of DPP8 mRNA | CTD | PMID:18593933 | zinc(0) | multiple interactions | ISO | DPP8 (Homo sapiens) | 6480464 | [PCI 5002 co-treated with Zinc] results in increased expression of DPP8 mRNA | CTD | PMID:18593933 | |