MLLT10 (MLLT10 histone lysine methyltransferase DOT1L cofactor) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: MLLT10 (MLLT10 histone lysine methyltransferase DOT1L cofactor) Homo sapiens
Analyze
Symbol: MLLT10
Name: MLLT10 histone lysine methyltransferase DOT1L cofactor
RGD ID: 1322026
HGNC Page HGNC
Description: Enables histone binding activity and nucleosome binding activity. Involved in positive regulation of transcription by RNA polymerase II. Located in cytosol and nucleoplasm. Part of protein-containing complex. Implicated in acute monocytic leukemia and acute myeloid leukemia.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AF10; ALL-1 fused gene from chromosome 10; ALL1-fused gene from chromosome 10 protein; DKFZp686E10210; MGC75086; MLLT10, histone lysine methyltransferase DOT1L cofactor; myeloid/lymphoid or mixed-lineage leukemia; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog), translocated to, 10; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); myeloid/lymphoid or mixed-lineage leukemia translocated to, 10; protein AF-10; translocated to, 10; type I AF10 protein; type III AF10 protein; type IV AF10 protein
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: MLLT10P1   MLLT10P2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1021,524,646 - 21,743,630 (+)EnsemblGRCh38hg38GRCh38
GRCh381021,524,616 - 21,743,630 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371021,822,685 - 22,032,559 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361021,863,108 - 22,072,560 (+)NCBINCBI36hg18NCBI36
Build 341021,863,107 - 22,072,560NCBI
Celera1021,495,732 - 21,720,297 (+)NCBI
Cytogenetic Map10p12.31NCBI
HuRef1021,476,633 - 21,694,284 (+)NCBIHuRef
CHM1_11021,823,893 - 22,033,408 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

Additional References at PubMed
PMID:7888665   PMID:9737689   PMID:10860745   PMID:10997963   PMID:11423977   PMID:11756182   PMID:11774384   PMID:12127405   PMID:12453419   PMID:12477932   PMID:12482966   PMID:12750376  
PMID:14702039   PMID:15164054   PMID:15851025   PMID:15856011   PMID:16215946   PMID:17043677   PMID:17868029   PMID:18029348   PMID:18037964   PMID:19322201   PMID:19443658   PMID:19913121  
PMID:20203130   PMID:20431927   PMID:20628086   PMID:20854876   PMID:20963938   PMID:21030982   PMID:21103407   PMID:21706055   PMID:21804547   PMID:21873635   PMID:22064352   PMID:23535729  
PMID:23535730   PMID:23670296   PMID:23673860   PMID:24755950   PMID:24981860   PMID:25464900   PMID:26439302   PMID:26480920   PMID:26496610   PMID:26638075   PMID:27859216   PMID:28514442  
PMID:29395067   PMID:30021884   PMID:30102091   PMID:31527241   PMID:32296183   PMID:32569758   PMID:33226740  


Genomics

Comparative Map Data
MLLT10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1021,524,646 - 21,743,630 (+)EnsemblGRCh38hg38GRCh38
GRCh381021,524,616 - 21,743,630 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371021,822,685 - 22,032,559 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361021,863,108 - 22,072,560 (+)NCBINCBI36hg18NCBI36
Build 341021,863,107 - 22,072,560NCBI
Celera1021,495,732 - 21,720,297 (+)NCBI
Cytogenetic Map10p12.31NCBI
HuRef1021,476,633 - 21,694,284 (+)NCBIHuRef
CHM1_11021,823,893 - 22,033,408 (+)NCBICHM1_1
Mllt10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39218,059,971 - 18,217,201 (+)NCBIGRCm39mm39
GRCm39 Ensembl218,060,048 - 18,217,199 (+)Ensembl
GRCm38218,055,160 - 18,212,390 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl218,055,237 - 18,212,388 (+)EnsemblGRCm38mm10GRCm38
MGSCv37217,976,898 - 18,134,017 (+)NCBIGRCm37mm9NCBIm37
MGSCv36217,973,025 - 18,130,144 (+)NCBImm8
Celera217,952,297 - 18,109,815 (+)NCBICelera
Cytogenetic Map2A3NCBI
Mllt10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21780,821,870 - 80,949,349 (+)NCBImRatBN7.2
Rnor_6.0 Ensembl1784,881,414 - 84,979,543 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01784,847,660 - 84,981,134 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01786,574,897 - 86,705,158 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41792,246,466 - 92,389,861 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11792,257,298 - 92,400,692 (+)NCBI
Celera1780,112,286 - 80,232,138 (+)NCBICelera
Cytogenetic Map17q12.3NCBI
Mllt10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554296,999,333 - 7,163,990 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554296,999,333 - 7,163,988 (-)NCBIChiLan1.0ChiLan1.0
MLLT10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11022,135,281 - 22,284,382 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1021,994,975 - 22,282,737 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01021,686,507 - 21,907,247 (+)NCBIMhudiblu_PPA_v0panPan3
MLLT10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1211,349,864 - 11,607,194 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl211,349,856 - 11,596,398 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha210,042,564 - 10,291,025 (-)NCBI
ROS_Cfam_1.029,598,648 - 9,848,677 (-)NCBI
UMICH_Zoey_3.128,911,703 - 9,160,725 (-)NCBI
UNSW_CanFamBas_1.028,996,500 - 9,245,212 (-)NCBI
UU_Cfam_GSD_1.029,172,316 - 9,421,340 (-)NCBI
Mllt10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934421,594,099 - 21,783,693 (+)NCBI
SpeTri2.0NW_0049365206,176,784 - 6,366,436 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MLLT10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1053,072,056 - 53,315,363 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11053,072,056 - 53,315,351 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21058,733,136 - 58,799,017 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Mllt10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247966,762,304 - 6,949,126 (-)NCBI

Position Markers
D10S211  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371021,907,887 - 21,908,088UniSTSGRCh37
Build 361021,947,893 - 21,948,094RGDNCBI36
Celera1021,595,650 - 21,595,845RGD
Cytogenetic Map10p12UniSTS
HuRef1021,570,206 - 21,570,401UniSTS
Marshfield Genetic Map1048.36RGD
Marshfield Genetic Map1048.36UniSTS
Genethon Genetic Map1046.2UniSTS
deCODE Assembly Map1046.11UniSTS
GeneMap99-GB4 RH Map10133.19UniSTS
Whitehead-RH Map10135.4UniSTS
Whitehead-YAC Contig Map10 UniSTS
SHGC-37264  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371022,004,262 - 22,004,396UniSTSGRCh37
Build 361022,044,268 - 22,044,402RGDNCBI36
Celera1021,692,006 - 21,692,140RGD
Cytogenetic Map10p12UniSTS
HuRef1021,666,425 - 21,666,559UniSTS
TNG Radiation Hybrid Map1011530.0UniSTS
Stanford-G3 RH Map101131.0UniSTS
NCBI RH Map10342.2UniSTS
GeneMap99-G3 RH Map101131.0UniSTS
SHGC-33568  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371022,015,647 - 22,015,780UniSTSGRCh37
Build 361022,055,653 - 22,055,786RGDNCBI36
Celera1021,703,390 - 21,703,523RGD
Cytogenetic Map10p12UniSTS
HuRef1021,677,499 - 21,677,632UniSTS
Stanford-G3 RH Map101100.0UniSTS
GeneMap99-GB4 RH Map10134.52UniSTS
Whitehead-RH Map10140.2UniSTS
NCBI RH Map10333.4UniSTS
GeneMap99-G3 RH Map101100.0UniSTS
RH44601  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371022,015,647 - 22,015,781UniSTSGRCh37
Build 361022,055,653 - 22,055,787RGDNCBI36
Celera1021,703,390 - 21,703,524RGD
Cytogenetic Map10p12UniSTS
HuRef1021,677,499 - 21,677,633UniSTS
GeneMap99-GB4 RH Map10134.08UniSTS
NCBI RH Map10346.8UniSTS
RH91239  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371022,004,076 - 22,004,231UniSTSGRCh37
Build 361022,044,082 - 22,044,237RGDNCBI36
Celera1021,691,820 - 21,691,975RGD
Cytogenetic Map10p12UniSTS
HuRef1021,666,239 - 21,666,394UniSTS
GeneMap99-GB4 RH Map10133.91UniSTS
RH102414  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371022,032,002 - 22,032,144UniSTSGRCh37
Build 361022,072,008 - 22,072,150RGDNCBI36
Celera1021,719,745 - 21,719,887RGD
Cytogenetic Map10p12UniSTS
HuRef1021,693,727 - 21,693,869UniSTS
GeneMap99-GB4 RH Map10134.3UniSTS
SHGC-85735  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371021,934,163 - 21,934,512UniSTSGRCh37
Build 361021,974,169 - 21,974,518RGDNCBI36
Celera1021,621,922 - 21,622,271RGD
Cytogenetic Map10p12UniSTS
HuRef1021,596,477 - 21,596,826UniSTS
TNG Radiation Hybrid Map1011480.0UniSTS
G59893  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371021,985,830 - 21,985,947UniSTSGRCh37
Build 361022,025,836 - 22,025,953RGDNCBI36
Celera1021,673,565 - 21,673,682RGD
Cytogenetic Map10p12UniSTS
HuRef1021,647,983 - 21,648,100UniSTS
TNG Radiation Hybrid Map1011519.0UniSTS
D10S2369  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371022,030,883 - 22,031,058UniSTSGRCh37
Build 361022,070,889 - 22,071,064RGDNCBI36
Celera1021,718,626 - 21,718,801RGD
Cytogenetic Map10p12UniSTS
HuRef1021,692,608 - 21,692,783UniSTS
GeneMap99-G3 RH Map101126.0UniSTS
MLLT10_1942  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371022,030,868 - 22,031,519UniSTSGRCh37
Build 361022,070,874 - 22,071,525RGDNCBI36
Celera1021,718,611 - 21,719,262RGD
HuRef1021,692,593 - 21,693,244UniSTS
RH48800  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371021,985,762 - 21,985,948UniSTSGRCh37
Build 361022,025,768 - 22,025,954RGDNCBI36
Celera1021,673,497 - 21,673,683RGD
Cytogenetic Map10p12UniSTS
HuRef1021,647,915 - 21,648,101UniSTS
GeneMap99-GB4 RH Map10134.02UniSTS
NCBI RH Map10270.0UniSTS
RH47336  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371021,845,852 - 21,846,034UniSTSGRCh37
Build 361021,885,858 - 21,886,040RGDNCBI36
Celera1021,533,619 - 21,533,801RGD
Cytogenetic Map10p12UniSTS
HuRef1021,508,096 - 21,508,278UniSTS
GeneMap99-GB4 RH Map10133.91UniSTS
RH45652  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371021,847,677 - 21,847,796UniSTSGRCh37
Build 361021,887,683 - 21,887,802RGDNCBI36
Celera1021,535,444 - 21,535,563RGD
Cytogenetic Map10p12UniSTS
HuRef1021,509,920 - 21,510,039UniSTS
GeneMap99-GB4 RH Map10134.3UniSTS
SHGC-34521  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371021,845,964 - 21,846,089UniSTSGRCh37
Build 361021,885,970 - 21,886,095RGDNCBI36
Celera1021,533,731 - 21,533,856RGD
Cytogenetic Map10p12UniSTS
HuRef1021,508,208 - 21,508,333UniSTS
Stanford-G3 RH Map101126.0UniSTS
GeneMap99-GB4 RH Map10133.63UniSTS
Whitehead-RH Map10137.0UniSTS
NCBI RH Map10337.4UniSTS
GeneMap99-G3 RH Map101126.0UniSTS
STS-U13948  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371022,031,128 - 22,031,404UniSTSGRCh37
Build 361022,071,134 - 22,071,410RGDNCBI36
Celera1021,718,871 - 21,719,147RGD
Cytogenetic Map10p12UniSTS
HuRef1021,692,853 - 21,693,129UniSTS
GeneMap99-GB4 RH Map10134.3UniSTS
WI-17659  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371021,964,885 - 21,965,034UniSTSGRCh37
Build 361022,004,891 - 22,005,040RGDNCBI36
Celera1021,652,619 - 21,652,768RGD
Cytogenetic Map10p12UniSTS
HuRef1021,627,046 - 21,627,195UniSTS
GeneMap99-GB4 RH Map10134.97UniSTS
Whitehead-RH Map10138.3UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:3623
Count of miRNA genes:956
Interacting mature miRNAs:1151
Transcripts:ENST00000307729, ENST00000377059, ENST00000377072, ENST00000377091, ENST00000377100, ENST00000420525, ENST00000430455, ENST00000438473, ENST00000446906, ENST00000462999, ENST00000468309, ENST00000471315, ENST00000476557, ENST00000479634, ENST00000480415, ENST00000495130
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 1876 1596 1292 246 1051 139 3660 1129 1517 210 1355 1547 119 1104 2139 4
Low 561 1373 434 378 881 326 696 1064 2213 209 105 65 54 1 100 649 1 2
Below cutoff 1 21 19 3 4 1 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_027818 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001195626 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001195627 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001195628 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001195630 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001324296 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001324297 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_004641 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_136736 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024448179 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024448180 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024448181 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024448182 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024448183 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024448184 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024448186 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024448187 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024448188 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024448190 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024448191 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024448192 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024448193 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024448194 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024448195 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024448197 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024448198 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024448199 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024448200 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024448201 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024448202 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024448203 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024448204 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024448205 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024448206 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002957016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB209755 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF060929 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF060934 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF060935 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF060936 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF060937 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF060938 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK128264 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK301213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK310803 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL137295 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL161799 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL357372 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL358780 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL359697 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY598745 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC032532 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC052798 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC065376 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC080577 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC094844 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC129946 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX640774 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX648210 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KF455214 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U13948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000307729   ⟹   ENSP00000307411
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1021,534,232 - 21,743,630 (+)Ensembl
RefSeq Acc Id: ENST00000377059   ⟹   ENSP00000366258
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1021,534,645 - 21,743,626 (+)Ensembl
RefSeq Acc Id: ENST00000377072   ⟹   ENSP00000366272
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1021,534,232 - 21,743,630 (+)Ensembl
RefSeq Acc Id: ENST00000377091   ⟹   ENSP00000366295
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1021,534,345 - 21,557,182 (+)Ensembl
RefSeq Acc Id: ENST00000377100   ⟹   ENSP00000366304
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1021,534,232 - 21,557,182 (+)Ensembl
RefSeq Acc Id: ENST00000420525   ⟹   ENSP00000399883
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1021,673,578 - 21,713,922 (+)Ensembl
RefSeq Acc Id: ENST00000430455   ⟹   ENSP00000397800
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1021,534,749 - 21,595,384 (+)Ensembl
RefSeq Acc Id: ENST00000438473   ⟹   ENSP00000408281
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1021,617,134 - 21,743,630 (+)Ensembl
RefSeq Acc Id: ENST00000462999   ⟹   ENSP00000498436
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1021,534,749 - 21,595,384 (+)Ensembl
RefSeq Acc Id: ENST00000468309
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1021,668,972 - 21,671,014 (+)Ensembl
RefSeq Acc Id: ENST00000471315
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1021,534,468 - 21,538,964 (+)Ensembl
RefSeq Acc Id: ENST00000476557
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1021,534,702 - 21,595,582 (+)Ensembl
RefSeq Acc Id: ENST00000479634
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1021,534,749 - 21,595,384 (+)Ensembl
RefSeq Acc Id: ENST00000480415
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1021,534,749 - 21,595,378 (+)Ensembl
RefSeq Acc Id: ENST00000495130   ⟹   ENSP00000499165
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1021,534,490 - 21,612,451 (+)Ensembl
RefSeq Acc Id: ENST00000621220   ⟹   ENSP00000484335
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1021,534,645 - 21,556,677 (+)Ensembl
RefSeq Acc Id: ENST00000631589   ⟹   ENSP00000488569
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1021,524,675 - 21,743,630 (+)Ensembl
RefSeq Acc Id: ENST00000650772   ⟹   ENSP00000498688
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1021,534,440 - 21,612,451 (+)Ensembl
RefSeq Acc Id: ENST00000650893   ⟹   ENSP00000499068
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1021,533,349 - 21,743,611 (+)Ensembl
RefSeq Acc Id: ENST00000650921
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1021,624,667 - 21,673,486 (+)Ensembl
RefSeq Acc Id: ENST00000651097   ⟹   ENSP00000498343
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1021,524,646 - 21,614,924 (+)Ensembl
RefSeq Acc Id: ENST00000651298   ⟹   ENSP00000498270
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1021,534,466 - 21,743,628 (+)Ensembl
RefSeq Acc Id: ENST00000651382
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1021,611,031 - 21,743,434 (+)Ensembl
RefSeq Acc Id: ENST00000651405
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1021,624,691 - 21,673,419 (+)Ensembl
RefSeq Acc Id: ENST00000652258   ⟹   ENSP00000498869
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1021,571,985 - 21,670,665 (+)Ensembl
RefSeq Acc Id: ENST00000652497   ⟹   ENSP00000498595
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1021,534,476 - 21,557,168 (+)Ensembl
RefSeq Acc Id: NM_001195626   ⟹   NP_001182555
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381021,534,232 - 21,743,630 (+)NCBI
GRCh371021,813,540 - 22,032,559 (+)NCBI
HuRef1021,476,633 - 21,694,284 (+)NCBI
CHM1_11021,824,369 - 22,033,408 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001195627   ⟹   NP_001182556
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381021,534,232 - 21,557,186 (+)NCBI
GRCh371021,813,540 - 22,032,559 (+)NCBI
HuRef1021,476,633 - 21,694,284 (+)NCBI
CHM1_11021,823,893 - 21,846,931 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001195628   ⟹   NP_001182557
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381021,534,232 - 21,557,186 (+)NCBI
GRCh371021,813,540 - 22,032,559 (+)NCBI
HuRef1021,476,633 - 21,694,284 (+)NCBI
CHM1_11021,823,893 - 21,846,931 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001195630   ⟹   NP_001182559
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381021,534,232 - 21,557,186 (+)NCBI
GRCh371021,813,540 - 22,032,559 (+)NCBI
HuRef1021,476,633 - 21,694,284 (+)NCBI
CHM1_11021,823,893 - 21,846,931 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001324296   ⟹   NP_001311225
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381021,533,756 - 21,557,186 (+)NCBI
CHM1_11021,823,070 - 21,846,931 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001324297   ⟹   NP_001311226
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381021,533,756 - 21,743,630 (+)NCBI
CHM1_11021,823,070 - 22,033,408 (+)NCBI
Sequence:
RefSeq Acc Id: NM_004641   ⟹   NP_004632
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381021,534,232 - 21,743,630 (+)NCBI
GRCh371021,813,540 - 22,032,559 (+)NCBI
Build 361021,863,108 - 22,072,560 (+)NCBI Archive
HuRef1021,476,633 - 21,694,284 (+)NCBI
CHM1_11021,823,893 - 22,033,408 (+)NCBI
Sequence:
RefSeq Acc Id: NR_136736
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381021,534,232 - 21,743,630 (+)NCBI
CHM1_11021,823,893 - 22,033,408 (+)NCBI
Sequence:
RefSeq Acc Id: XM_024448179   ⟹   XP_024303947
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381021,534,350 - 21,743,630 (+)NCBI
Sequence:
RefSeq Acc Id: XM_024448180   ⟹   XP_024303948
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381021,534,321 - 21,743,319 (+)NCBI
Sequence:
RefSeq Acc Id: XM_024448181   ⟹   XP_024303949
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381021,533,725 - 21,743,319 (+)NCBI
Sequence:
RefSeq Acc Id: XM_024448182   ⟹   XP_024303950
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381021,524,616 - 21,743,319 (+)NCBI
Sequence:
RefSeq Acc Id: XM_024448183   ⟹   XP_024303951
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381021,534,350 - 21,743,319 (+)NCBI
Sequence:
RefSeq Acc Id: XM_024448184   ⟹   XP_024303952
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381021,534,350 - 21,743,319 (+)NCBI
Sequence:
RefSeq Acc Id: XM_024448186   ⟹   XP_024303954
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381021,534,350 - 21,743,319 (+)NCBI
Sequence:
RefSeq Acc Id: XM_024448187   ⟹   XP_024303955
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381021,534,350 - 21,743,319 (+)NCBI
Sequence:
RefSeq Acc Id: XM_024448188   ⟹   XP_024303956
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381021,534,321 - 21,743,319 (+)NCBI
Sequence:
RefSeq Acc Id: XM_024448190   ⟹   XP_024303958
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381021,534,350 - 21,743,319 (+)NCBI
Sequence:
RefSeq Acc Id: XM_024448191   ⟹   XP_024303959
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381021,534,350 - 21,743,630 (+)NCBI
Sequence:
RefSeq Acc Id: XM_024448192   ⟹   XP_024303960
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381021,534,749 - 21,743,319 (+)NCBI
Sequence:
RefSeq Acc Id: XM_024448193   ⟹   XP_024303961
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381021,557,697 - 21,743,319 (+)NCBI
Sequence:
RefSeq Acc Id: XM_024448194   ⟹   XP_024303962
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381021,534,127 - 21,743,319 (+)NCBI
Sequence:
RefSeq Acc Id: XM_024448195   ⟹   XP_024303963
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381021,534,127 - 21,743,319 (+)NCBI
Sequence:
RefSeq Acc Id: XM_024448197   ⟹   XP_024303965
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381021,534,127 - 21,743,319 (+)NCBI
Sequence:
RefSeq Acc Id: XM_024448198   ⟹   XP_024303966
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381021,524,651 - 21,743,319 (+)NCBI
Sequence:
RefSeq Acc Id: XM_024448199   ⟹   XP_024303967
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381021,534,127 - 21,743,319 (+)NCBI
Sequence:
RefSeq Acc Id: XM_024448200   ⟹   XP_024303968
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381021,524,649 - 21,743,319 (+)NCBI
Sequence:
RefSeq Acc Id: XM_024448201   ⟹   XP_024303969
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381021,622,330 - 21,743,319 (+)NCBI
Sequence:
RefSeq Acc Id: XM_024448202   ⟹   XP_024303970
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381021,535,498 - 21,743,319 (+)NCBI
Sequence:
RefSeq Acc Id: XM_024448203   ⟹   XP_024303971
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381021,635,040 - 21,743,319 (+)NCBI
Sequence:
RefSeq Acc Id: XM_024448204   ⟹   XP_024303972
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381021,534,350 - 21,743,319 (+)NCBI
Sequence:
RefSeq Acc Id: XM_024448205   ⟹   XP_024303973
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381021,534,350 - 21,743,319 (+)NCBI
Sequence:
RefSeq Acc Id: XM_024448206   ⟹   XP_024303974
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381021,534,350 - 21,692,693 (+)NCBI
Sequence:
RefSeq Acc Id: XR_002957016
RefSeq Status:
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381021,534,350 - 21,740,108 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001182555 (Get FASTA)   NCBI Sequence Viewer  
  NP_001182556 (Get FASTA)   NCBI Sequence Viewer  
  NP_001182557 (Get FASTA)   NCBI Sequence Viewer  
  NP_001182559 (Get FASTA)   NCBI Sequence Viewer  
  NP_001311225 (Get FASTA)   NCBI Sequence Viewer  
  NP_001311226 (Get FASTA)   NCBI Sequence Viewer  
  NP_004632 (Get FASTA)   NCBI Sequence Viewer  
  XP_024303947 (Get FASTA)   NCBI Sequence Viewer  
  XP_024303948 (Get FASTA)   NCBI Sequence Viewer  
  XP_024303949 (Get FASTA)   NCBI Sequence Viewer  
  XP_024303950 (Get FASTA)   NCBI Sequence Viewer  
  XP_024303951 (Get FASTA)   NCBI Sequence Viewer  
  XP_024303952 (Get FASTA)   NCBI Sequence Viewer  
  XP_024303954 (Get FASTA)   NCBI Sequence Viewer  
  XP_024303955 (Get FASTA)   NCBI Sequence Viewer  
  XP_024303956 (Get FASTA)   NCBI Sequence Viewer  
  XP_024303958 (Get FASTA)   NCBI Sequence Viewer  
  XP_024303959 (Get FASTA)   NCBI Sequence Viewer  
  XP_024303960 (Get FASTA)   NCBI Sequence Viewer  
  XP_024303961 (Get FASTA)   NCBI Sequence Viewer  
  XP_024303962 (Get FASTA)   NCBI Sequence Viewer  
  XP_024303963 (Get FASTA)   NCBI Sequence Viewer  
  XP_024303965 (Get FASTA)   NCBI Sequence Viewer  
  XP_024303966 (Get FASTA)   NCBI Sequence Viewer  
  XP_024303967 (Get FASTA)   NCBI Sequence Viewer  
  XP_024303968 (Get FASTA)   NCBI Sequence Viewer  
  XP_024303969 (Get FASTA)   NCBI Sequence Viewer  
  XP_024303970 (Get FASTA)   NCBI Sequence Viewer  
  XP_024303971 (Get FASTA)   NCBI Sequence Viewer  
  XP_024303972 (Get FASTA)   NCBI Sequence Viewer  
  XP_024303973 (Get FASTA)   NCBI Sequence Viewer  
  XP_024303974 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA79972 (Get FASTA)   NCBI Sequence Viewer  
  AAC16701 (Get FASTA)   NCBI Sequence Viewer  
  AAC16706 (Get FASTA)   NCBI Sequence Viewer  
  AAC16707 (Get FASTA)   NCBI Sequence Viewer  
  AAC16708 (Get FASTA)   NCBI Sequence Viewer  
  AAC16709 (Get FASTA)   NCBI Sequence Viewer  
  AAC16710 (Get FASTA)   NCBI Sequence Viewer  
  AAH80577 (Get FASTA)   NCBI Sequence Viewer  
  AAT47519 (Get FASTA)   NCBI Sequence Viewer  
  BAD92992 (Get FASTA)   NCBI Sequence Viewer  
  BAG62788 (Get FASTA)   NCBI Sequence Viewer  
  CAE45872 (Get FASTA)   NCBI Sequence Viewer  
  CAI46260 (Get FASTA)   NCBI Sequence Viewer  
  EAW86161 (Get FASTA)   NCBI Sequence Viewer  
  EAW86162 (Get FASTA)   NCBI Sequence Viewer  
  EAW86163 (Get FASTA)   NCBI Sequence Viewer  
  EAW86164 (Get FASTA)   NCBI Sequence Viewer  
  EAW86165 (Get FASTA)   NCBI Sequence Viewer  
  P55197 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_004632   ⟸   NM_004641
- Peptide Label: isoform a
- UniProtKB: P55197 (UniProtKB/Swiss-Prot),   Q59EQ6 (UniProtKB/TrEMBL),   Q6N002 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001182556   ⟸   NM_001195627
- Peptide Label: isoform d
- UniProtKB: P55197 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001182559   ⟸   NM_001195630
- Peptide Label: isoform e
- UniProtKB: P55197 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001182557   ⟸   NM_001195628
- Peptide Label: isoform e
- UniProtKB: P55197 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001182555   ⟸   NM_001195626
- Peptide Label: isoform c
- UniProtKB: P55197 (UniProtKB/Swiss-Prot),   Q59EQ6 (UniProtKB/TrEMBL),   Q6N002 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001311226   ⟸   NM_001324297
- Peptide Label: isoform f
- Sequence:
RefSeq Acc Id: NP_001311225   ⟸   NM_001324296
- Peptide Label: isoform e
- UniProtKB: P55197 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_024303950   ⟸   XM_024448182
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_024303968   ⟸   XM_024448200
- Peptide Label: isoform X10
- Sequence:
RefSeq Acc Id: XP_024303966   ⟸   XM_024448198
- Peptide Label: isoform X10
- Sequence:
RefSeq Acc Id: XP_024303949   ⟸   XM_024448181
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_024303962   ⟸   XM_024448194
- Peptide Label: isoform X10
- Sequence:
RefSeq Acc Id: XP_024303965   ⟸   XM_024448197
- Peptide Label: isoform X10
- Sequence:
RefSeq Acc Id: XP_024303963   ⟸   XM_024448195
- Peptide Label: isoform X10
- Sequence:
RefSeq Acc Id: XP_024303967   ⟸   XM_024448199
- Peptide Label: isoform X10
- Sequence:
RefSeq Acc Id: XP_024303948   ⟸   XM_024448180
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_024303956   ⟸   XM_024448188
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_024303947   ⟸   XM_024448179
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_024303959   ⟸   XM_024448191
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_024303972   ⟸   XM_024448204
- Peptide Label: isoform X14
- Sequence:
RefSeq Acc Id: XP_024303973   ⟸   XM_024448205
- Peptide Label: isoform X15
- Sequence:
RefSeq Acc Id: XP_024303952   ⟸   XM_024448184
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_024303951   ⟸   XM_024448183
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_024303954   ⟸   XM_024448186
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_024303958   ⟸   XM_024448190
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_024303955   ⟸   XM_024448187
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_024303974   ⟸   XM_024448206
- Peptide Label: isoform X16
- Sequence:
RefSeq Acc Id: XP_024303960   ⟸   XM_024448192
- Peptide Label: isoform X9
- Sequence:
RefSeq Acc Id: XP_024303970   ⟸   XM_024448202
- Peptide Label: isoform X12
- Sequence:
RefSeq Acc Id: XP_024303961   ⟸   XM_024448193
- Peptide Label: isoform X9
- Sequence:
RefSeq Acc Id: XP_024303969   ⟸   XM_024448201
- Peptide Label: isoform X11
- Sequence:
RefSeq Acc Id: XP_024303971   ⟸   XM_024448203
- Peptide Label: isoform X13
- Sequence:
RefSeq Acc Id: ENSP00000498436   ⟸   ENST00000462999
RefSeq Acc Id: ENSP00000408281   ⟸   ENST00000438473
RefSeq Acc Id: ENSP00000307411   ⟸   ENST00000307729
RefSeq Acc Id: ENSP00000484335   ⟸   ENST00000621220
RefSeq Acc Id: ENSP00000499068   ⟸   ENST00000650893
RefSeq Acc Id: ENSP00000498688   ⟸   ENST00000650772
RefSeq Acc Id: ENSP00000498270   ⟸   ENST00000651298
RefSeq Acc Id: ENSP00000498343   ⟸   ENST00000651097
RefSeq Acc Id: ENSP00000366295   ⟸   ENST00000377091
RefSeq Acc Id: ENSP00000366258   ⟸   ENST00000377059
RefSeq Acc Id: ENSP00000366272   ⟸   ENST00000377072
RefSeq Acc Id: ENSP00000366304   ⟸   ENST00000377100
RefSeq Acc Id: ENSP00000498869   ⟸   ENST00000652258
RefSeq Acc Id: ENSP00000499165   ⟸   ENST00000495130
RefSeq Acc Id: ENSP00000498595   ⟸   ENST00000652497
RefSeq Acc Id: ENSP00000397800   ⟸   ENST00000430455
RefSeq Acc Id: ENSP00000399883   ⟸   ENST00000420525
RefSeq Acc Id: ENSP00000488569   ⟸   ENST00000631589
Protein Domains
PHD   PHD-type

Promoters
RGD ID:7217149
Promoter ID:EPDNEW_H14320
Type:initiation region
Name:MLLT10_2
Description:myeloid/lymphoid or mixed-lineage leukemia; translocated to,10
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H14319  EPDNEW_H14323  EPDNEW_H14322  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381021,524,616 - 21,524,676EPDNEW
RGD ID:7217155
Promoter ID:EPDNEW_H14322
Type:initiation region
Name:MLLT10_1
Description:myeloid/lymphoid or mixed-lineage leukemia; translocated to,10
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H14319  EPDNEW_H14320  EPDNEW_H14323  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381021,534,236 - 21,534,296EPDNEW
RGD ID:7217153
Promoter ID:EPDNEW_H14323
Type:initiation region
Name:MLLT10_3
Description:myeloid/lymphoid or mixed-lineage leukemia; translocated to,10
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H14319  EPDNEW_H14320  EPDNEW_H14322  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381021,534,346 - 21,534,406EPDNEW
RGD ID:6787345
Promoter ID:HG_KWN:8819
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000396529,   NM_001009569,   OTTHUMT00000047135,   OTTHUMT00000047136,   OTTHUMT00000047139,   OTTHUMT00000047145,   OTTHUMT00000047146,   OTTHUMT00000047147,   UC001IQR.1,   UC001IQU.1,   UC001IQV.1,   UC001IQW.1,   UC001IQX.1,   UC009XKE.1,   UC009XKF.1
Position:
Human AssemblyChrPosition (strand)Source
Build 361021,862,776 - 21,863,677 (+)MPROMDB

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 10p15.3-12.2(chr10:90221-22567425)x3 copy number gain See cases [RCV000053508] Chr10:90221..22567425 [GRCh38]
Chr10:224406..22856354 [GRCh37]
Chr10:126161..22896360 [NCBI36]
Chr10:10p15.3-12.2
pathogenic
GRCh38/hg38 10p15.3-12.1(chr10:90421-29058318)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053512]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053512]|See cases [RCV000053512] Chr10:90421..29058318 [GRCh38]
Chr10:224406..29347247 [GRCh37]
Chr10:126361..29387253 [NCBI36]
Chr10:10p15.3-12.1
pathogenic
GRCh38/hg38 10p12.31(chr10:21125825-21721227)x3 copy number gain See cases [RCV000135392] Chr10:21125825..21721227 [GRCh38]
Chr10:21414754..22010156 [GRCh37]
Chr10:21454760..22050162 [NCBI36]
Chr10:10p12.31
uncertain significance
GRCh38/hg38 10p14-12.31(chr10:7428770-21587752)x1 copy number loss See cases [RCV000137307] Chr10:7428770..21587752 [GRCh38]
Chr10:7470732..21876681 [GRCh37]
Chr10:7510738..21916687 [NCBI36]
Chr10:10p14-12.31
pathogenic|uncertain significance
GRCh38/hg38 10p15.3-12.1(chr10:90205-26339978)x3 copy number gain See cases [RCV000138428] Chr10:90205..26339978 [GRCh38]
Chr10:224406..26628907 [GRCh37]
Chr10:126145..26668913 [NCBI36]
Chr10:10p15.3-12.1
pathogenic
GRCh38/hg38 10p12.31-11.22(chr10:19088161-32732293)x3 copy number gain See cases [RCV000139427] Chr10:19088161..32732293 [GRCh38]
Chr10:19377090..33021221 [GRCh37]
Chr10:19417096..33061227 [NCBI36]
Chr10:10p12.31-11.22
likely pathogenic
GRCh38/hg38 10p12.31(chr10:20964970-22049554)x3 copy number gain See cases [RCV000139644] Chr10:20964970..22049554 [GRCh38]
Chr10:21253899..22338483 [GRCh37]
Chr10:21293905..22378489 [NCBI36]
Chr10:10p12.31
uncertain significance
GRCh38/hg38 10p15.1-q11.22(chr10:4604734-48074662)x3 copy number gain See cases [RCV000141497] Chr10:4604734..48074662 [GRCh38]
Chr10:4646926..47531169 [GRCh37]
Chr10:4636926..47125152 [NCBI36]
Chr10:10p15.1-q11.22
benign
GRCh37/hg19 10p15.3-11.23(chr10:100026-30278548)x3 copy number gain See cases [RCV000447131] Chr10:100026..30278548 [GRCh37]
Chr10:10p15.3-11.23
pathogenic
GRCh37/hg19 10p15.3-q26.3(chr10:93297-135378918)x3 copy number gain See cases [RCV000448750] Chr10:93297..135378918 [GRCh37]
Chr10:10p15.3-q26.3
pathogenic
GRCh37/hg19 10p12.31-12.2(chr10:21881989-23129991)x3 copy number gain See cases [RCV000511886] Chr10:21881989..23129991 [GRCh37]
Chr10:10p12.31-12.2
uncertain significance
GRCh37/hg19 10p15.3-q26.3(chr10:100027-135427143) copy number gain See cases [RCV000511389] Chr10:100027..135427143 [GRCh37]
Chr10:10p15.3-q26.3
pathogenic|uncertain significance
GRCh37/hg19 10p15.3-q26.3(chr10:100027-135427143)x3 copy number gain See cases [RCV000510861] Chr10:100027..135427143 [GRCh37]
Chr10:10p15.3-q26.3
pathogenic
GRCh37/hg19 10p15.3-q11.23(chr10:100026-50961640)x3 copy number gain See cases [RCV000510893] Chr10:100026..50961640 [GRCh37]
Chr10:10p15.3-q11.23
pathogenic
GRCh37/hg19 10p12.31(chr10:21709301-21824727)x1 copy number loss not provided [RCV000737035] Chr10:21709301..21824727 [GRCh37]
Chr10:10p12.31
benign
GRCh37/hg19 10p12.31(chr10:21800977-21837799)x3 copy number gain not provided [RCV000737037] Chr10:21800977..21837799 [GRCh37]
Chr10:10p12.31
benign
GRCh37/hg19 10p15.3-q26.3(chr10:73232-135524321)x3 copy number gain not provided [RCV000749464] Chr10:73232..135524321 [GRCh37]
Chr10:10p15.3-q26.3
pathogenic
GRCh37/hg19 10p15.3-q26.3(chr10:98087-135477883)x3 copy number gain not provided [RCV000749465] Chr10:98087..135477883 [GRCh37]
Chr10:10p15.3-q26.3
pathogenic
NM_001195626.3(MLLT10):c.1991-7A>G single nucleotide variant not provided [RCV000897057] Chr10:21727849 [GRCh38]
Chr10:22016778 [GRCh37]
Chr10:10p12.31
benign
GRCh37/hg19 10p12.31(chr10:19774176-22330966)x1 copy number loss not provided [RCV000847282] Chr10:19774176..22330966 [GRCh37]
Chr10:10p12.31
uncertain significance
NM_001195626.3(MLLT10):c.1731G>A (p.Ser577=) single nucleotide variant not provided [RCV000958152] Chr10:21713803 [GRCh38]
Chr10:22002732 [GRCh37]
Chr10:10p12.31
benign
NM_001195626.3(MLLT10):c.1226G>C (p.Gly409Ala) single nucleotide variant Acute myeloid leukemia [RCV001336718] Chr10:21673524 [GRCh38]
Chr10:21962453 [GRCh37]
Chr10:10p12.31
uncertain significance

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:16063 AgrOrtholog
COSMIC MLLT10 COSMIC
Ensembl Genes ENSG00000078403 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000307411 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000366258 UniProtKB/Swiss-Prot
  ENSP00000366272 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000366295 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000366304 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000397800 UniProtKB/TrEMBL
  ENSP00000399883 UniProtKB/TrEMBL
  ENSP00000408281 ENTREZGENE, UniProtKB/TrEMBL
  ENSP00000484335 UniProtKB/Swiss-Prot
  ENSP00000488569 UniProtKB/Swiss-Prot
  ENSP00000498270 UniProtKB/TrEMBL
  ENSP00000498343 UniProtKB/TrEMBL
  ENSP00000498436 UniProtKB/TrEMBL
  ENSP00000498595 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000498688 UniProtKB/TrEMBL
  ENSP00000499068 UniProtKB/TrEMBL
  ENSP00000499165 UniProtKB/TrEMBL
Ensembl Transcript ENST00000307729 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000377059 UniProtKB/Swiss-Prot
  ENST00000377072 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000377091 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000377100 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000420525 UniProtKB/TrEMBL
  ENST00000430455 UniProtKB/TrEMBL
  ENST00000438473 ENTREZGENE, UniProtKB/TrEMBL
  ENST00000462999 UniProtKB/TrEMBL
  ENST00000495130 UniProtKB/TrEMBL
  ENST00000621220 UniProtKB/Swiss-Prot
  ENST00000631589 UniProtKB/Swiss-Prot
  ENST00000650772 UniProtKB/TrEMBL
  ENST00000650893 UniProtKB/TrEMBL
  ENST00000651097 UniProtKB/TrEMBL
  ENST00000651298 ENTREZGENE, UniProtKB/TrEMBL
  ENST00000652497 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000078403 GTEx
HGNC ID HGNC:16063 ENTREZGENE
Human Proteome Map MLLT10 Human Proteome Map
InterPro EPHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Zinc_finger_PHD-type_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_FYVE_PHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_PHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_PHD-finger UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:8028 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 8028 ENTREZGENE
OMIM 601626 OMIM
  602409 OMIM
PharmGKB PA30849 PharmGKB
PROSITE EPHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_PHD_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_PHD_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART PHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF57903 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A494C038_HUMAN UniProtKB/TrEMBL
  A0A494C093_HUMAN UniProtKB/TrEMBL
  A0A494C0R2_HUMAN UniProtKB/TrEMBL
  A0A494C1P9_HUMAN UniProtKB/TrEMBL
  AF10_HUMAN UniProtKB/Swiss-Prot
  H0Y5C4_HUMAN UniProtKB/TrEMBL
  H0Y5P4_HUMAN UniProtKB/TrEMBL
  P55197 ENTREZGENE
  Q59EQ6 ENTREZGENE, UniProtKB/TrEMBL
  Q5JT35_HUMAN UniProtKB/TrEMBL
  Q6N002 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary B1ANA8 UniProtKB/Swiss-Prot
  Q5JT37 UniProtKB/Swiss-Prot
  Q5VX90 UniProtKB/Swiss-Prot
  Q66K63 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-01-29 MLLT10  MLLT10 histone lysine methyltransferase DOT1L cofactor    MLLT10, histone lysine methyltransferase DOT1L cofactor  Symbol and/or name change 5135510 APPROVED
2017-05-16 MLLT10  MLLT10, histone lysine methyltransferase DOT1L cofactor    myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10  Symbol and/or name change 5135510 APPROVED
2015-06-30 MLLT10  myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10    myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10  Symbol and/or name change 5135510 APPROVED