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Gene: POU6F2 (POU class 6 homeobox 2) Homo sapiens
Symbol: POU6F2
Name: POU class 6 homeobox 2
Description: Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in several processes, including ganglion mother cell fate determination; regulation of transcription, DNA-templated; and visual perception. Predicted to localize to the nuclear chromatin. Implicated in nephroblastoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: POU domain class 6 transcription factor 2; POU domain, class 6, transcription factor 2; retina-derived POU domain factor 1; retina-derived POU-domain factor-1; RPF-1; Wilms tumor suppressor locus; WT5; WTSL
Mus musculus (house mouse) : Pou6f2 (POU domain, class 6, transcription factor 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pou6f2 (POU class 6 homeobox 2)
Chinchilla lanigera (long-tailed chinchilla) : Pou6f2 (POU class 6 homeobox 2)
Pan paniscus (bonobo/pygmy chimpanzee) : POU6F2 (POU class 6 homeobox 2)
Canis lupus familiaris (dog) : LOC483249 (POU domain, class 6, transcription factor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pou6f2 (POU class 6 homeobox 2)
Sus scrofa (pig) : POU6F2 (POU class 6 homeobox 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl738,977,998 - 39,493,095 (+)Ensembl
GRCh38738,977,909 - 39,468,601 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37739,017,609 - 39,504,390 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36739,012,933 - 39,470,915 (+)NCBINCBI36hg18NCBI36
Build 34738,819,647 - 39,277,630NCBI
Celera739,005,468 - 39,491,972 (+)NCBI
Cytogenetic Map7p14.1NCBI
HuRef739,263,229 - 39,387,744 (+)NCBIHuRef
HuRef738,901,808 - 39,131,455 (+)NCBIHuRef
CHM1_1739,020,250 - 39,507,035 (+)NCBICHM1_1
CRA_TCAGchr7v2739,055,332 - 39,542,296 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on POU6F2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1322006
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.