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Gene: ZBTB21 (zinc finger and BTB domain containing 21) Homo sapiens
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Symbol: ZBTB21
Name: zinc finger and BTB domain containing 21
Description: Exhibits several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; POZ domain binding activity; and methyl-CpG binding activity. Involved in negative regulation of transcription by RNA polymerase II. Localizes to cytosol and nucleoplasm; INTERACTS WITH 15-acetyldeoxynivalenol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: DKFZp781N1974; zinc finger and BTB domain-containing protein 21; zinc finger protein 295; ZNF295
Orthologs:
Mus musculus (house mouse) : Zbtb21 (zinc finger and BTB domain containing 21)  MGI  Alliance
Rattus norvegicus (Norway rat) : Zbtb21 (zinc finger and BTB domain containing 21)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Zbtb21 (zinc finger and BTB domain containing 21)
Pan paniscus (bonobo/pygmy chimpanzee) : ZBTB21 (zinc finger and BTB domain containing 21)
Canis lupus familiaris (dog) : ZBTB21 (zinc finger and BTB domain containing 21)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Zbtb21 (zinc finger and BTB domain containing 21)
Sus scrofa (pig) : ZBTB21 (zinc finger and BTB domain containing 21)
Chlorocebus sabaeus (African green monkey) : ZBTB21 (zinc finger and BTB domain containing 21)
Heterocephalus glaber (naked mole-rat) : Zbtb21 (zinc finger and BTB domain containing 21)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2141,986,831 - 42,010,387 (-)EnsemblGRCh38hg38GRCh38
GRCh382141,986,831 - 42,010,418 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372143,406,940 - 43,430,496 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362142,280,009 - 42,303,565 (-)NCBINCBI36hg18NCBI36
Build 342142,280,008 - 42,303,519NCBI
Celera2128,554,479 - 28,578,036 (-)NCBI
Cytogenetic Map21q22.3NCBI
HuRef2128,824,422 - 28,847,984 (-)NCBIHuRef
CHM1_12142,967,781 - 42,991,342 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on ZBTB21
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1321974
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.