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Gene: PTGES2 (prostaglandin E synthase 2) Homo sapiens
Symbol: PTGES2
Name: prostaglandin E synthase 2
Description: Exhibits prostaglandin-E synthase activity. Predicted to be involved in cyclooxygenase pathway and neutrophil degranulation. Localizes to mitochondrion.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: C9orf15; FLJ14038; gamma-interferon-activated transcriptional element-binding factor 1; GATE-binding factor 1; GBF-1; GBF1; membrane-associated prostaglandin E synthase 2; membrane-associated prostaglandin E synthase-2; MGC11289; microsomal prostaglandin E synthase 2; microsomal prostaglandin E synthase-2; mPGE synthase-2; mPGES-2; PGES2; prostaglandin-H(2) E-isomerase
Mus musculus (house mouse) : Ptges2 (prostaglandin E synthase 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ptges2 (prostaglandin E synthase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ptges2 (prostaglandin E synthase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PTGES2 (prostaglandin E synthase 2)
Canis lupus familiaris (dog) : PTGES2 (prostaglandin E synthase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ptges2 (prostaglandin E synthase 2)
Sus scrofa (pig) : PTGES2 (prostaglandin E synthase 2)
Chlorocebus sabaeus (African green monkey) : PTGES2 (prostaglandin E synthase 2)
Heterocephalus glaber (naked mole-rat) : Ptges2 (prostaglandin E synthase 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl9128,120,693 - 128,128,462 (-)EnsemblGRCh38hg38GRCh38
GRCh389128,120,693 - 128,128,462 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh379130,882,972 - 130,890,741 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369129,922,793 - 129,930,533 (-)NCBINCBI36hg18NCBI36
Build 349127,962,526 - 127,970,266NCBI
Celera9101,534,900 - 101,542,641 (-)NCBI
Cytogenetic Map9q34.11NCBI
HuRef9100,497,534 - 100,505,316 (-)NCBIHuRef
CHM1_19131,034,931 - 131,042,710 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on PTGES2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1321966
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.