Gene: GPR132 (G protein-coupled receptor 132) Homo sapiens
Symbol: GPR132
Name: G protein-coupled receptor 132
Description: This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein was reported to be a receptor for lysophosphatidylcholine action, but PubMedID: 15653487 retracts this finding and instead suggests this protein to be an effector of lysophosphatidylcholine action. This protein may have proton-sensing activity and may be a receptor for oxidized free fatty acids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: G protein-coupled receptor G2A; G2 accumulation protein; G2A; MGC99642; probable G-protein coupled receptor 132
Mus musculus (house mouse) : Gpr132 (G protein-coupled receptor 132)  MGI  Alliance
Rattus norvegicus (Norway rat) : Gpr132 (G protein-coupled receptor 132)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gpr132 (G protein-coupled receptor 132)
Pan paniscus (bonobo/pygmy chimpanzee) : GPR132 (G protein-coupled receptor 132)
Canis lupus familiaris (dog) : GPR132 (G protein-coupled receptor 132)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gpr132 (G protein-coupled receptor 132)
Sus scrofa (pig) : GPR132 (G protein-coupled receptor 132)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh3814105,049,389 - 105,065,550 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3714105,515,726 - 105,531,887 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3614104,586,782 - 104,602,799 (-)NCBINCBI36hg18NCBI36
Build 3414104,586,782 - 104,602,799NCBI
Celera1485,569,212 - 85,585,228 (-)NCBI
Cytogenetic Map14q32.33NCBI
HuRef1485,709,317 - 85,725,273 (-)NCBIHuRef
CHM1_114105,453,498 - 105,469,670 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on GPR132
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1321937
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-06-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.