Fanci (Fanconi anemia, complementation group I) - Rat Genome Database

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Gene: Fanci (Fanconi anemia, complementation group I) Mus musculus
Analyze
Symbol: Fanci
Name: Fanconi anemia, complementation group I
RGD ID: 1321934
MGI Page MGI
Description: Predicted to enable DNA polymerase binding activity. Predicted to be involved in DNA repair. Predicted to act upstream of or within positive regulation of protein ubiquitination. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of DNA repair complex and Fanconi anaemia nuclear complex. Human ortholog(s) of this gene implicated in Fanconi anemia; Fanconi anemia complementation group I; and female breast cancer. Orthologous to human FANCI (FA complementation group I).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Fanconi anemia group I protein homolog; MGC38195; MGC38407
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39779,042,056 - 79,100,013 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl779,041,677 - 79,100,012 (+)EnsemblGRCm39 Ensembl
GRCm38779,392,312 - 79,450,266 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl779,391,929 - 79,450,264 (+)EnsemblGRCm38mm10GRCm38
MGSCv37786,537,224 - 86,595,150 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36779,265,866 - 79,323,777 (+)NCBIMGSCv36mm8
Celera776,790,497 - 76,852,630 (+)NCBICelera
Cytogenetic Map7D2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1-naphthyl isothiocyanate  (ISO)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,2',5,5'-tetrachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-methylcholine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-fluorouracil  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
amphetamine  (ISO)
arsenite(3-)  (ISO)
asbestos  (ISO)
avobenzone  (ISO)
azathioprine  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
calcitriol  (ISO)
cannabidiol  (ISO)
carbamazepine  (ISO)
carbon nanotube  (EXP)
cisplatin  (EXP,ISO)
cobalt dichloride  (ISO)
coumarin  (ISO)
coumestrol  (ISO)
Cuprizon  (ISO)
curcumin  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
dichloroacetic acid  (EXP)
dicrotophos  (ISO)
digitoxin  (ISO)
digoxin  (ISO)
dioxygen  (ISO)
doxorubicin  (ISO)
Enterolactone  (ISO)
enzyme inhibitor  (ISO)
fragrance  (ISO)
genistein  (ISO)
hydrogen peroxide  (ISO)
indometacin  (ISO)
ivermectin  (ISO)
Lasiocarpine  (ISO)
lead(0)  (ISO)
lead(2+)  (ISO)
lucanthone  (ISO)
methyl methanesulfonate  (ISO)
mitomycin C  (ISO)
N-Nitrosopyrrolidine  (ISO)
ouabain  (ISO)
ozone  (EXP)
palbociclib  (ISO)
paracetamol  (ISO)
PCB138  (EXP)
perfluorooctanoic acid  (EXP)
phenethyl isothiocyanate  (ISO)
piroxicam  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
progesterone  (ISO)
propanal  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
T-2 toxin  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
thapsigargin  (ISO)
titanium dioxide  (EXP)
topotecan  (ISO)
trimellitic anhydride  (EXP)
triptonide  (EXP)
trovafloxacin  (EXP)
urethane  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Identification of the Fanconi anemia complementation group I gene, FANCI. Dorsman JC, etal., Cell Oncol. 2007;29(3):211-8.
2. Familial breast cancer and DNA repair genes: Insights into known and novel susceptibility genes from the GENESIS study, and implications for multigene panel testing. Girard E, etal., Int J Cancer. 2019 Apr 15;144(8):1962-1974. doi: 10.1002/ijc.31921. Epub 2018 Nov 13.
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. Mouse MP Annotation Import Pipeline RGD automated import pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Novel FANCI mutations in Fanconi anemia with VACTERL association. Savage SA, etal., Am J Med Genet A. 2016 Feb;170A(2):386-91. doi: 10.1002/ajmg.a.37461. Epub 2015 Nov 21.
8. Downregulation of Fanconi anemia genes in sporadic head and neck squamous cell carcinoma. Wreesmann VB, etal., ORL J Otorhinolaryngol Relat Spec. 2007;69(4):218-25. Epub 2007 Apr 4.
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11125038   PMID:11217851   PMID:12466851   PMID:12477932   PMID:12904583   PMID:14610273   PMID:14691545   PMID:16141072   PMID:16141073  
PMID:17015433   PMID:17967808   PMID:18799693   PMID:18931676   PMID:21677750   PMID:21764741   PMID:21873635   PMID:26625197   PMID:26658019   PMID:27073218   PMID:28378742   PMID:31219578  
PMID:31472450   PMID:32325033   PMID:34373449   PMID:35969748  


Genomics

Comparative Map Data
Fanci
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39779,042,056 - 79,100,013 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl779,041,677 - 79,100,012 (+)EnsemblGRCm39 Ensembl
GRCm38779,392,312 - 79,450,266 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl779,391,929 - 79,450,264 (+)EnsemblGRCm38mm10GRCm38
MGSCv37786,537,224 - 86,595,150 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36779,265,866 - 79,323,777 (+)NCBIMGSCv36mm8
Celera776,790,497 - 76,852,630 (+)NCBICelera
Cytogenetic Map7D2NCBI
FANCI
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381589,243,979 - 89,317,259 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1589,243,945 - 89,317,261 (+)EnsemblGRCh38hg38GRCh38
GRCh371589,787,210 - 89,860,490 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361587,588,198 - 87,661,366 (+)NCBINCBI36Build 36hg18NCBI36
Celera1566,188,469 - 66,261,721 (+)NCBICelera
Cytogenetic Map15q26.1NCBI
HuRef1565,899,078 - 65,972,245 (+)NCBIHuRef
CHM1_11589,628,176 - 89,701,402 (+)NCBICHM1_1
T2T-CHM13v2.01586,998,773 - 87,072,086 (+)NCBIT2T-CHM13v2.0
Fanci
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21133,327,264 - 133,383,661 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1133,327,297 - 133,383,640 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01141,116,565 - 141,172,997 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1141,120,166 - 141,172,483 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01142,078,658 - 142,134,772 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41135,144,029 - 135,196,828 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1125,390,494 - 125,446,830 (+)NCBICelera
Cytogenetic Map1q31NCBI
Fanci
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541615,788,922 - 15,853,480 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541615,788,812 - 15,857,933 (-)NCBIChiLan1.0ChiLan1.0
FANCI
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan11582,496,027 - 82,569,303 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01567,935,882 - 68,009,033 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11587,142,871 - 87,215,271 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1587,142,871 - 87,215,271 (+)Ensemblpanpan1.1panPan2
FANCI
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1352,282,955 - 52,357,874 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl352,282,731 - 52,357,226 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha354,917,864 - 54,992,648 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0352,700,699 - 52,774,876 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl352,700,713 - 52,774,871 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1352,223,438 - 52,297,602 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0352,433,730 - 52,507,862 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0352,772,736 - 52,847,574 (+)NCBIUU_Cfam_GSD_1.0
Fanci
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640131,154,626 - 131,236,280 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648315,106,902 - 15,179,094 (+)EnsemblSpeTri2.0
SpeTri2.0NW_00493648315,096,215 - 15,179,856 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FANCI
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl754,811,027 - 54,889,998 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1754,811,024 - 54,889,992 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2759,782,093 - 59,865,530 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FANCI
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1297,788,983 - 7,864,505 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl297,790,458 - 7,855,552 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605938,950,782 - 39,037,352 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fanci
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476816,427,060 - 16,493,850 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Fanci
2229 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1879
Count of miRNA genes:711
Interacting mature miRNAs:910
Transcripts:ENSMUST00000036865, ENSMUST00000117227, ENSMUST00000118959, ENSMUST00000126456, ENSMUST00000132091, ENSMUST00000137667
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300722Sle3_msystemic lupus erythmatosus susceptibility 3 (mouse)Not determined7351172887142720Mouse
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76502999133501729Mouse
12792978Fbmd3_mfemoral bone mineral density 3, females only (mouse)77050288142367832Mouse
10412199Sst2_msusceptibility to tuberculosis 2 (mouse)Not determined718728794119485380Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719147398141919804Mouse
4141805Sle19_msystematic lupus erythematosus susceptibility 19 (mouse)Not determined3003248581135653Mouse
26884404Huml1_mhumerus length 1, 5 week (mouse)730199425108999207Mouse
1301514Rigs1_mradiation induced gastroschisis 1 (mouse)Not determined73628001592394346Mouse
1301082Bbaa16_mB.burgdorferi-associated arthritis 16 (mouse)Not determined736280015116416877Mouse
25314303Vmm4_mvariable multisystem mineralization 4, kidney (mouse)73729942587049208Mouse
1300791Abbp3_mA/J and C57BL/6 blood pressure 3 (mouse)Not determined739673887103510010Mouse
10043926Bw1n_mbody weight 1 in NSY (mouse)Not determined745161966118693530Mouse
12880417V125Dq5_mvitamin D active form serum level QTL 5 (mouse)74524974879249748Mouse
1302141Fcsa6_mfemoral cross-sectional area 6 (mouse)Not determined74838446182384607Mouse
11532741Tbrs5_mtuberculosis resistance 5 (mouse)74915922783235415Mouse
1357752Tabw_mtally ho asscoiated body weight (mouse)Not determined74919327883193390Mouse
10053685Eae43_mexperimental allergic encephalomyelitis susceptibility 43 (mouse)Not determined75112495485125093Mouse
10054064Bwq11_mbody weight QTL 11 (mouse)Not determined75112495485125093Mouse
13208555Lgth10_mbody length 10 (mouse)751649748125599172Mouse
12880418V125Dq6_mvitamin D active form serum level QTL 6 (mouse)75214974886149748Mouse
27226751Femd5_mfemur midshaft diameter 5, 10 week (mouse)753249748143153737Mouse
25823170Hrsq7_mhost response to SARS QTL 7, log titer (mouse)754819589116822815Mouse
11565101Tsve1_mvariable short tail (Tsv) enhancer 1 (mouse)75588950887142720Mouse
27226778Femd11_mfemur midshaft diameter 11, 16 week (mouse)756949748134001729Mouse
1300952Hcs1_mhepatocarcinogenesis susceptibility 1 (mouse)Not determined75732612191326352Mouse
1301465Egrm3_mearly growth rate (mouse)Not determined75732612191326352Mouse
1301663Skull9_mskull morphology 9 (mouse)Not determined75732612191326352Mouse
26884408Bzwq13_mbi-zygomatic width QTL 13, 16 week (mouse)761749748121399223Mouse
27095916Scvln15_msacral vertebrae length 2, 16 week (mouse)761749748123699223Mouse
25314305Vmm6_mvariable multisystem mineralization 6, eye (mouse)761849748102749207Mouse
1301383Aem2_manti-erythrocyte autoantibody modifier 2 (mouse)Not determined76413542498135653Mouse
26884381Bzwq2_mbi-zygomatic width QTL 2, 5 week (mouse)76524974896949207Mouse
26884440Sklq4_mskull length QTL 4, 5 week (mouse)765249748126499172Mouse
11553865Stmm1c_mskin tumor modifier of MSM 1c (mouse)76578898699788986Mouse
11553866Stmm1d_mskin tumor modifier of MSM 1d (mouse)76578898699788986Mouse
27095937Ulnl7_mulna length 7, 10 week (mouse)76644974898349207Mouse
12801463Rta1_mretinal aging 1 (mouse)76716802789089989Mouse
1301826Pgia3_mproteoglycan induced arthritis 3 (mouse)Not determined767290094101290240Mouse
1301784Ses2_msalmonella enteritidis susceptibility 2 (mouse)Not determined767290094101290240Mouse
1300620Pgia21_mproteoglycan induced arthritis 21 (mouse)Not determined767290094101290240Mouse
26884418Bzwq7_mbi-zygomatic width QTL 7, 10 week (mouse)767849748105449207Mouse
27226715Metcl3_mmetatarsal-calcaneal length 3, 5 week (mouse)767849748119499223Mouse
26884444Sklq8_mskull length QTL 8, 10 week (mouse)767849748124199223Mouse
26884451Sklq14_mskull length QTL 14, 16 week (mouse)767849748124999172Mouse
1300654Bomd1_mbone mineral density 1 (mouse)Not determined768365595102365702Mouse
27095907Scvln4_msacral vertebrae length 2, 5 week (mouse)769949748120499223Mouse
1301155Bpq7_mblood pressure QTL 7 (mouse)Not determined770143137104143379Mouse
10043973Obq29_mobesity QTL 29 (mouse)Not determined772263372106263372Mouse
4142319Powg_mpost-ovarectomy weight gain (mouse)Not determined7285710592582163Mouse
27095910Pglq13_mpelvic girdle length QTL 13, 16 week (mouse)773049748125699172Mouse
27095933Ulnl3_mulna length 3, 5 week (mouse)773149748143153737Mouse
11553869Stmm2b_mskin tumor modifier of MSM 2a (mouse)773725965107725965Mouse
4142212Png1_mPostnatal growth 1 (mouse)Not determined7432612192394346Mouse
27226745Metcl9_mmetatarsal-calcaneal length 9, 10 week (mouse)774849748122199223Mouse
27226781Tibl3_mtibia length 3, 5 week (mouse)774849748122199223Mouse
1301566Adip3_madiposity 3 (mouse)Not determined775394215109394346Mouse
14746989Manh62_mmandible shape 62 (mouse)775742528109742528Mouse
26884398Humsd6_mhumerus midshaft diameter 6, 16 week (mouse)778649748136901729Mouse

Markers in Region
RH125851  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38779,449,583 - 79,449,832UniSTSGRCm38
MGSCv37786,594,469 - 86,594,718UniSTSGRCm37
Celera776,851,949 - 76,852,198UniSTS
Cytogenetic Map7D3UniSTS
Cytogenetic Map7EUniSTS
Whitehead/MRC_RH7778.28UniSTS
D7Jpk3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38779,433,189 - 79,433,329UniSTSGRCm38
MGSCv37786,578,075 - 86,578,215UniSTSGRCm37
Celera776,835,557 - 76,835,697UniSTS
Cytogenetic Map7D3UniSTS
cM Map737.0UniSTS
MARC_7859-7860:996688105:3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38779,449,991 - 79,450,632UniSTSGRCm38
MGSCv37786,594,877 - 86,595,518UniSTSGRCm37
Celera776,852,357 - 76,852,998UniSTS
Cytogenetic Map7EUniSTS
Cytogenetic Map7D3UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_145946 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006540738 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011250833 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017322082 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036152857 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC110909 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC160464 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK085572 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC027836 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BF021012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX519311 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY754860 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466543 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CN458387 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CN702700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CO426844 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DV655910 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000036865   ⟹   ENSMUSP00000044931
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl779,042,060 - 79,100,012 (+)Ensembl
GRCm38.p6 Ensembl779,392,312 - 79,450,264 (+)Ensembl
RefSeq Acc Id: ENSMUST00000118959   ⟹   ENSMUSP00000114122
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl779,042,056 - 79,059,330 (+)Ensembl
GRCm38.p6 Ensembl779,392,308 - 79,409,582 (+)Ensembl
RefSeq Acc Id: ENSMUST00000126456   ⟹   ENSMUSP00000114513
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl779,041,677 - 79,051,634 (+)Ensembl
GRCm38.p6 Ensembl779,391,929 - 79,401,886 (+)Ensembl
RefSeq Acc Id: ENSMUST00000132091   ⟹   ENSMUSP00000122113
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl779,042,101 - 79,100,012 (+)Ensembl
GRCm38.p6 Ensembl779,392,353 - 79,450,264 (+)Ensembl
RefSeq Acc Id: ENSMUST00000137667   ⟹   ENSMUSP00000117992
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl779,048,884 - 79,085,439 (+)Ensembl
GRCm38.p6 Ensembl779,399,136 - 79,435,691 (+)Ensembl
RefSeq Acc Id: ENSMUST00000205817   ⟹   ENSMUSP00000146293
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl779,062,484 - 79,076,984 (+)Ensembl
GRCm38.p6 Ensembl779,412,736 - 79,427,236 (+)Ensembl
RefSeq Acc Id: ENSMUST00000206121   ⟹   ENSMUSP00000146237
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl779,090,416 - 79,095,474 (+)Ensembl
GRCm38.p6 Ensembl779,440,668 - 79,445,726 (+)Ensembl
RefSeq Acc Id: NM_145946   ⟹   NP_666058
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39779,042,086 - 79,100,012 (+)NCBI
GRCm38779,392,338 - 79,450,264 (+)NCBI
MGSCv37786,537,224 - 86,595,150 (+)RGD
Celera776,790,497 - 76,852,630 (+)RGD
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006540738   ⟹   XP_006540801
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39779,042,056 - 79,100,013 (+)NCBI
GRCm38779,392,312 - 79,450,266 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011250833   ⟹   XP_011249135
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39779,042,056 - 79,089,345 (+)NCBI
GRCm38779,392,312 - 79,439,596 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017322082   ⟹   XP_017177571
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39779,045,683 - 79,100,013 (+)NCBI
GRCm38779,395,933 - 79,450,266 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036152857   ⟹   XP_036008750
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39779,042,071 - 79,100,013 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_666058   ⟸   NM_145946
- UniProtKB: Q8R3G8 (UniProtKB/Swiss-Prot),   Q8K368 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006540801   ⟸   XM_006540738
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_011249135   ⟸   XM_011250833
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_017177571   ⟸   XM_017322082
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSMUSP00000114122   ⟸   ENSMUST00000118959
RefSeq Acc Id: ENSMUSP00000146237   ⟸   ENSMUST00000206121
RefSeq Acc Id: ENSMUSP00000146293   ⟸   ENSMUST00000205817
RefSeq Acc Id: ENSMUSP00000122113   ⟸   ENSMUST00000132091
RefSeq Acc Id: ENSMUSP00000114513   ⟸   ENSMUST00000126456
RefSeq Acc Id: ENSMUSP00000044931   ⟸   ENSMUST00000036865
RefSeq Acc Id: ENSMUSP00000117992   ⟸   ENSMUST00000137667
RefSeq Acc Id: XP_036008750   ⟸   XM_036152857
- Peptide Label: isoform X2
Protein Domains
FANCI helical   FANCI solenoid   FANCI solenoid 1 cap

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8K368-F1-model_v2 AlphaFold Q8K368 1-1330 view protein structure

Promoters
RGD ID:8664501
Promoter ID:EPDNEW_M10282
Type:multiple initiation site
Name:Fanci_1
Description:Mus musculus Fanconi anemia, complementation group I , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38779,392,327 - 79,392,387EPDNEW
RGD ID:6841086
Promoter ID:MM_KWN:51226
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   ES_Cell,   Kidney,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000036896,   ENSMUST00000117227,   ENSMUST00000118959,   NM_145946,   OTTMUST00000072118,   OTTMUST00000072119
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36786,536,834 - 86,537,334 (+)MPROMDB
RGD ID:6841085
Promoter ID:MM_KWN:51227
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:ES_Cell
Transcripts:OTTMUST00000072117
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36786,543,636 - 86,544,136 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2384790 AgrOrtholog
Ensembl Genes ENSMUSG00000039187 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000044931 ENTREZGENE
  ENSMUSP00000044931.7 UniProtKB/Swiss-Prot
  ENSMUSP00000114122.2 UniProtKB/TrEMBL
  ENSMUSP00000114513.2 UniProtKB/TrEMBL
  ENSMUSP00000117992 ENTREZGENE
  ENSMUSP00000117992.2 UniProtKB/TrEMBL
  ENSMUSP00000122113.2 UniProtKB/Swiss-Prot
  ENSMUSP00000146237.2 UniProtKB/TrEMBL
  ENSMUSP00000146293.2 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000036865 ENTREZGENE
  ENSMUST00000036865.13 UniProtKB/Swiss-Prot
  ENSMUST00000118959.8 UniProtKB/TrEMBL
  ENSMUST00000126456.8 UniProtKB/TrEMBL
  ENSMUST00000132091.8 UniProtKB/Swiss-Prot
  ENSMUST00000137667 ENTREZGENE
  ENSMUST00000137667.3 UniProtKB/TrEMBL
  ENSMUST00000205817.2 UniProtKB/TrEMBL
  ENSMUST00000206121.2 UniProtKB/TrEMBL
InterPro FANCI UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FANCI_HD1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FANCI_HD2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FANCI_S1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FANCI_S1-cap UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FANCI_S2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FANCI_S3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FANCI_S4 UniProtKB/Swiss-Prot
KEGG Report mmu:208836 UniProtKB/Swiss-Prot
MGD MGI:2384790 ENTREZGENE
NCBI Gene 208836 ENTREZGENE
PANTHER FANCONI ANEMIA GROUP I PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR21818 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam FANCI_HD1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FANCI_HD2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FANCI_S1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FANCI_S1-cap UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FANCI_S2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FANCI_S3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FANCI_S4 UniProtKB/Swiss-Prot
PhenoGen Fanci PhenoGen
UniProt A0A0U1RQ41_MOUSE UniProtKB/TrEMBL
  A0A0U1RQ89_MOUSE UniProtKB/TrEMBL
  D3YVC7_MOUSE UniProtKB/TrEMBL
  F2Z414_MOUSE UniProtKB/TrEMBL
  F7ALG5_MOUSE UniProtKB/TrEMBL
  FANCI_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q8R3G8 ENTREZGENE
UniProt Secondary Q8BUE9 UniProtKB/Swiss-Prot
  Q8R3G8 UniProtKB/Swiss-Prot