Aass (aminoadipate-semialdehyde synthase) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Aass (aminoadipate-semialdehyde synthase) Mus musculus
Analyze
Symbol: Aass
Name: aminoadipate-semialdehyde synthase
RGD ID: 1321930
MGI Page MGI
Description: Enables saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity and saccharopine dehydrogenase (NADP+, L-lysine-forming) activity. Acts upstream of or within L-lysine catabolic process. Predicted to be located in mitochondrion. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and sensory organ. Human ortholog(s) of this gene implicated in hyperlysinemia. Orthologous to human AASS (aminoadipate-semialdehyde synthase).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: alpha-aminoadipic semialdehyde synthase, mitochondrial; LKR; LKR/SDH; Lo; LOR; LOR/SDH; Lorsdh; lysine oxoglutarate reductase; saccharopine dehydrogenase; SDH
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39623,072,172 - 23,132,985 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl623,072,172 - 23,132,985 (-)EnsemblGRCm39 Ensembl
GRCm38623,072,173 - 23,132,986 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl623,072,173 - 23,132,986 (-)EnsemblGRCm38mm10GRCm38
MGSCv37623,022,173 - 23,082,986 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36623,022,171 - 23,082,975 (-)NCBIMGSCv36mm8
Celera623,117,896 - 23,183,403 (-)NCBICelera
Cytogenetic Map6A3.1NCBI
cM Map610.27NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (EXP)
1,2-dimethylhydrazine  (EXP)
1-benzylpiperazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
3-chloropropane-1,2-diol  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4-hydroxyphenyl retinamide  (EXP)
6-propyl-2-thiouracil  (ISO)
acetamide  (ISO)
acrylamide  (EXP)
aflatoxin B1  (EXP)
aristolochic acid A  (ISO)
arsane  (EXP)
arsenic atom  (EXP)
avobenzone  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bromobenzene  (ISO)
buspirone  (ISO)
carbon nanotube  (EXP)
cefaloridine  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (EXP)
cisplatin  (ISO)
cobalt dichloride  (ISO)
coumarin  (ISO)
cyclosporin A  (EXP,ISO)
cypermethrin  (EXP)
cyproconazole  (EXP)
decabromodiphenyl ether  (EXP)
dioxygen  (EXP)
dorsomorphin  (ISO)
elemental selenium  (ISO)
endosulfan  (ISO)
epoxiconazole  (EXP)
ethanol  (EXP)
flutamide  (ISO)
fumonisin B1  (EXP)
furan  (ISO)
gold atom  (ISO)
gold(0)  (ISO)
hydrogen peroxide  (ISO)
iodide salt  (ISO)
ivermectin  (ISO)
leflunomide  (ISO)
maneb  (EXP)
methapyrilene  (ISO)
methidathion  (EXP)
nickel sulfate  (ISO)
O-methyleugenol  (ISO)
ozone  (EXP,ISO)
p-toluidine  (ISO)
paracetamol  (ISO)
paraquat  (EXP)
pentachlorophenol  (EXP)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (EXP,ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
propanal  (ISO)
propiconazole  (EXP)
quercetin  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
sevoflurane  (ISO)
silicon dioxide  (ISO)
silver atom  (EXP)
silver(0)  (EXP)
sodium arsenite  (EXP,ISO)
sulforaphane  (EXP)
sunitinib  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (ISO)
titanium dioxide  (EXP)
valproic acid  (EXP,ISO)
vancomycin  (EXP)
vitamin E  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Mootha VK, etal., Cell 2003 Nov 26;115(5):629-40.
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:10567204   PMID:10567240   PMID:11042159   PMID:11076861   PMID:11163791   PMID:11217851   PMID:12466851   PMID:12477932   PMID:14610273   PMID:14681479   PMID:15489334  
PMID:16141072   PMID:16141073   PMID:18614015   PMID:18936211   PMID:19083499   PMID:21677750   PMID:21873635   PMID:22174793   PMID:32968282  


Genomics

Comparative Map Data
Aass
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39623,072,172 - 23,132,985 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl623,072,172 - 23,132,985 (-)EnsemblGRCm39 Ensembl
GRCm38623,072,173 - 23,132,986 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl623,072,173 - 23,132,986 (-)EnsemblGRCm38mm10GRCm38
MGSCv37623,022,173 - 23,082,986 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36623,022,171 - 23,082,975 (-)NCBIMGSCv36mm8
Celera623,117,896 - 23,183,403 (-)NCBICelera
Cytogenetic Map6A3.1NCBI
cM Map610.27NCBI
AASS
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387122,073,549 - 122,144,249 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7122,064,583 - 122,144,308 (-)EnsemblGRCh38hg38GRCh38
GRCh377121,713,603 - 121,784,303 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367121,503,423 - 121,561,112 (-)NCBINCBI36Build 36hg18NCBI36
Build 347121,310,137 - 121,367,827NCBI
Celera7116,522,826 - 116,593,571 (-)NCBICelera
Cytogenetic Map7q31.32NCBI
HuRef7116,077,048 - 116,147,810 (-)NCBIHuRef
CHM1_17121,646,898 - 121,717,645 (-)NCBICHM1_1
T2T-CHM13v2.07123,389,454 - 123,460,169 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27121,108,272 - 121,179,018 (-)NCBI
Aass
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8452,572,146 - 52,628,811 (-)NCBIGRCr8
mRatBN7.2451,606,461 - 51,663,136 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl451,606,462 - 51,663,136 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx456,573,037 - 56,636,497 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0452,494,066 - 52,557,519 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0450,935,584 - 50,999,363 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0450,152,005 - 50,208,935 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl450,152,452 - 50,200,328 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0449,938,569 - 49,993,864 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4449,479,938 - 49,539,782 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1449,710,958 - 49,806,368 (-)NCBI
Celera446,798,734 - 46,861,408 (-)NCBICelera
Cytogenetic Map4q22NCBI
Aass
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554793,742,757 - 3,814,338 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554793,746,003 - 3,805,835 (-)NCBIChiLan1.0ChiLan1.0
AASS
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26158,945,704 - 159,016,545 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1710,955,958 - 11,026,799 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07114,084,792 - 114,155,558 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17126,769,655 - 126,840,346 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7126,769,655 - 126,840,346 (-)Ensemblpanpan1.1panPan2
AASS
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11459,950,123 - 59,993,457 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1459,951,216 - 60,000,212 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1459,366,730 - 59,419,159 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01459,984,503 - 60,037,014 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1459,986,237 - 60,035,749 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11460,076,161 - 60,128,175 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01459,703,783 - 59,756,172 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01460,081,118 - 60,133,517 (-)NCBIUU_Cfam_GSD_1.0
Aass
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511849,012,960 - 49,067,984 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366053,136,018 - 3,190,948 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366053,135,977 - 3,190,956 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AASS
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1824,974,754 - 25,039,195 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11824,938,366 - 25,039,197 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21826,579,353 - 26,641,402 (+)NCBISscrofa10.2Sscrofa10.2susScr3
AASS
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12190,891,781 - 90,959,351 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2190,892,023 - 90,959,343 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604212,584,431 - 12,655,125 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Aass
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478313,831,150 - 13,902,082 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478313,831,220 - 13,904,806 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Aass
2460 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:406
Count of miRNA genes:267
Interacting mature miRNAs:281
Transcripts:ENSMUST00000031707, ENSMUST00000138063, ENSMUST00000149864, ENSMUST00000152280
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12904934Edlmmq4_mextensor digitorum longus muscle mass QTL 4 (mouse)6125514064Mouse
12904942Tammq3_mtibialis anterior muscle mass QTL 3 (mouse)6125514064Mouse
12904955Gmmq3_mgastrocnemius muscle mass QTL 3 (mouse)6125514064Mouse
1301131Chol2_mcholesterol 2 (mouse)Not determined6132144495Mouse
5491191Mobq2_mmultigenic obesity QTL 2 (mouse)Not determined6132144495Mouse
1302024Skull7_mskull morphology 7 (mouse)Not determined6132144495Mouse
15039372Nmrs22_mNAFLD-associated magnetic resonance shift 22 (mouse)6147633435476334Mouse
25440480Moaq2_mmodifier of alien QTL 2 (mouse)63050001117476961Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139076998Mouse
1300731Smdq3_msegregation of mitochondrial DNA QTL 3 (mouse)Not determined6424920638249325Mouse
1300556Cia6_mcollagen induced arthritis QTL 6 (mouse)Not determined6446488487403016Mouse
11353836Bmiq1_mbody mass index QTL 1 (mouse)6450382329751333Mouse
11353840Bmiq2_mbody mass index QTL 2 (mouse)6450382345291115Mouse
1357520Axtq2_manxiety QTL 2 (mouse)Not determined6450382348703611Mouse
1357481Aaj2_manxiety in A/J 2 (mouse)Not determined6450382348703611Mouse
11353841Bmiq3_mbody mass index QTL 3 (mouse)6450382348703611Mouse
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396633110Mouse
4142232W6q4_mweight 6 weeks QTL 4 (mouse)Not determined450382396633110Mouse
4142126W3q3_mweight 3 weeks QTL 3 (mouse)Not determined450382396633110Mouse
4142361W10q11_mweight 10 weeks QTL 11 (mouse)Not determined450382396633110Mouse
26884441Sklq3_mskull length QTL 3, 5 week (mouse)6760000080576983Mouse
1302051Sluc7_msusceptibility to lung cancer 7 (mouse)Not determined6929707443297168Mouse
10043869Cia6a_mcollagen induced arthritis QTL 6a (mouse)Not determined61211797146118069Mouse
4141749Obrq2_mobesity resistance QTL 2 (mouse)Not determined1275122146751333Mouse
1301998Bts2_mbladder tumor susceptibility 2 (mouse)Not determined61275122146751333Mouse
27226726Tibmd7_mtibia midshaft diameter 7, 16 week (mouse)61769999953476985Mouse
1301850Fglu_mfasting glucose (mouse)Not determined61771159851711719Mouse
1301724Pcd4ts1_mp-glycoprotein positive CD4 T cell subset 1 (mouse)Not determined61771159851711719Mouse
4140989Spqq2_msperm quality QTL 2 (mouse)Not determined1771159851711719Mouse
1357442Dbts1_mdiabetes 1 (mouse)Not determined61823414773364675Mouse
12904940Edlmmq5_mextensor digitorum longus muscle mass QTL 5 (mouse)61961634653616346Mouse
12904943Tammq4_mtibialis anterior muscle mass QTL 4 (mouse)61961634653616346Mouse
12904952Gmmq4_mgastrocnemius muscle mass QTL 4 (mouse)61961634653616346Mouse
10412213Sxbq2_mSGC/Knj cross B6 QTL 2 (mouse)Not determined61991268571299759Mouse
10412107Desp4_mdespair 4 (mouse)Not determined62004983054049830Mouse

Markers in Region
Aass  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map6A3.1UniSTS
cM Map64.5UniSTS
D6Mit204  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38623,131,816 - 23,131,963UniSTSGRCm38
MGSCv37623,081,816 - 23,081,963UniSTSGRCm37
Celera623,182,233 - 23,182,380UniSTS
Cytogenetic Map6A3.1UniSTS
cM Map64.4UniSTS
Whitehead Genetic63.3UniSTS
Whitehead_YAC6 UniSTS
AJ224761  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38623,072,889 - 23,072,969UniSTSGRCm38
MGSCv37623,022,889 - 23,022,969UniSTSGRCm37
Celera623,118,612 - 23,118,692UniSTS
Cytogenetic Map6A3.1UniSTS
Aass  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map6A3.1UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000031707   ⟹   ENSMUSP00000031707
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl623,072,172 - 23,132,985 (-)Ensembl
GRCm38.p6 Ensembl623,072,173 - 23,132,986 (-)Ensembl
RefSeq Acc Id: ENSMUST00000138063
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl623,092,282 - 23,127,579 (-)Ensembl
GRCm38.p6 Ensembl623,092,283 - 23,127,580 (-)Ensembl
RefSeq Acc Id: ENSMUST00000149864   ⟹   ENSMUSP00000115079
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl623,092,282 - 23,127,611 (-)Ensembl
GRCm38.p6 Ensembl623,092,283 - 23,127,612 (-)Ensembl
RefSeq Acc Id: ENSMUST00000152280
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl623,109,476 - 23,132,915 (-)Ensembl
GRCm38.p6 Ensembl623,109,477 - 23,132,916 (-)Ensembl
RefSeq Acc Id: NM_013930   ⟹   NP_038958
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39623,072,172 - 23,132,985 (-)NCBI
GRCm38623,072,173 - 23,132,986 (-)ENTREZGENE
MGSCv37623,022,173 - 23,082,986 (-)RGD
Celera623,117,896 - 23,183,403 (-)RGD
cM Map6 ENTREZGENE
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_038958   ⟸   NM_013930
- UniProtKB: Q9Z1I9 (UniProtKB/Swiss-Prot),   Q99K67 (UniProtKB/Swiss-Prot),   Q3UEQ9 (UniProtKB/TrEMBL),   Q3UWN2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000031707   ⟸   ENSMUST00000031707
RefSeq Acc Id: ENSMUSP00000115079   ⟸   ENSMUST00000149864
Protein Domains
Alanine dehydrogenase/pyridine nucleotide   Saccharopine dehydrogenase NADP binding

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q99K67-F1-model_v2 AlphaFold Q99K67 1-926 view protein structure

Promoters
RGD ID:6838798
Promoter ID:MM_KWN:45285
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Liver
Transcripts:ENSMUST00000031707,   OTTMUST00000057415
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36623,082,791 - 23,083,291 (-)MPROMDB
RGD ID:6889094
Promoter ID:EPDNEW_M7998
Type:multiple initiation site
Name:Aass_1
Description:Mus musculus aminoadipate-semialdehyde synthase , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38623,132,927 - 23,132,987EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1353573 AgrOrtholog
Ensembl Genes ENSMUSG00000029695 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000031707 ENTREZGENE
  ENSMUST00000031707.14 UniProtKB/Swiss-Prot
  ENSMUST00000149864.2 UniProtKB/TrEMBL
Gene3D-CATH Domain 3, Saccharopine reductase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NAD(P)-binding Rossmann-like Domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro AlaDH/PNT_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AlaDH/PNT_NAD(H)-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NAD(P)-bd_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sacchrp_dh_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sacchrp_dh_NADP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:30956 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1353573 ENTREZGENE
NCBI Gene 30956 ENTREZGENE
PANTHER ALPHA-AMINOADIPIC SEMIALDEHYDE SYNTHASE, MITOCHONDRIAL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SACCHAROPINE DEHYDROGENASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam AlaDh_PNT_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sacchrp_dh_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sacchrp_dh_NADP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Aass PhenoGen
SMART AlaDh_PNT_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AlaDh_PNT_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Formate/glycerate dehydrogenase catalytic domain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF51735 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt AASS_MOUSE UniProtKB/Swiss-Prot
  F6VMP2_MOUSE UniProtKB/TrEMBL
  Q3UEQ9 ENTREZGENE, UniProtKB/TrEMBL
  Q3UWN2 ENTREZGENE, UniProtKB/TrEMBL
  Q99K67 ENTREZGENE
  Q9Z1I9 ENTREZGENE
UniProt Secondary Q9Z1I9 UniProtKB/Swiss-Prot