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Gene: LANCL2 (LanC like 2) Homo sapiens
Symbol: LANCL2
Name: LanC like 2
Description: Exhibits phosphatidylinositol-3-phosphate binding activity; phosphatidylinositol-4-phosphate binding activity; and phosphatidylinositol-5-phosphate binding activity. Involved in negative regulation of transcription, DNA-templated and positive regulation of abscisic acid-activated signaling pathway. Localizes to several cellular components, including cortical actin cytoskeleton; cytosol; and nucleoplasm; INTERACTS WITH 2-hydroxypropanoic acid; 2-methylcholine; 5-aza-2'-deoxycytidine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: G protein-coupled receptor 69B; GPR69B; LanC (bacterial lantibiotic synthetase component C)-like 2; LanC lantibiotic synthetase component C-like 2; lanC-like protein 2; MGC87139; TASP; testis-specific adriamycin sensitivity protein
Mus musculus (house mouse) : Lancl2 (LanC (bacterial lantibiotic synthetase component C)-like 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Lancl2 (LanC like 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lancl2 (LanC like 2)
Pan paniscus (bonobo/pygmy chimpanzee) : LANCL2 (LanC like 2)
Canis lupus familiaris (dog) : LANCL2 (LanC like 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lancl2 (LanC like 2)
Sus scrofa (pig) : LANCL2 (LanC like 2)
Chlorocebus sabaeus (African green monkey) : LANCL2 (LanC like 2)
Heterocephalus glaber (naked mole-rat) : Lancl2 (LanC like 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl755,365,448 - 55,433,742 (+)EnsemblGRCh38hg38GRCh38
GRCh38755,365,448 - 55,433,742 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37755,433,141 - 55,501,435 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36755,400,635 - 55,468,929 (+)NCBINCBI36hg18NCBI36
Build 34755,207,349 - 55,275,644NCBI
Celera755,536,348 - 55,604,629 (+)NCBI
Cytogenetic Map7p11.2NCBI
HuRef755,268,359 - 55,336,642 (+)NCBIHuRef
CHM1_1755,435,807 - 55,504,119 (+)NCBICHM1_1
CRA_TCAGchr7v2755,437,426 - 55,505,717 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on LANCL2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1321926
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.