Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Mlph (melanophilin) Mus musculus
Analyze
Symbol: Mlph
Name: melanophilin
Description: Exhibits Rab GTPase binding activity and cytoskeletal protein binding activity. Involved in melanocyte differentiation; melanosome localization; and protein targeting. Localizes to the cytoskeleton and melanosome. Colocalizes with the microtubule plus-end. Human ortholog(s) of this gene implicated in Griscelli syndrome type 3. Is expressed in several structures, including genitourinary system; gut; liver; lung; and spleen. Orthologous to human MLPH (melanophilin); INTERACTS WITH 1,1-dichloroethene; 4-hydroxyphenyl retinamide; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2210418F23Rik; 5031433I09Rik; AW228792; D1Wsu84e; exophilin-3; l(1)-3Rk; l1Rk3; leaden protein; ln; Slac-2a; slaC2-a; slp homolog lacking C2 domains a; synaptotagmin-like protein 2a
Orthologs:
Homo sapiens (human) : MLPH (melanophilin)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Mlph (melanophilin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mlph (melanophilin)
Pan paniscus (bonobo/pygmy chimpanzee) : MLPH (melanophilin)
Canis lupus familiaris (dog) : MLPH (melanophilin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mlph (melanophilin)
Sus scrofa (pig) : MLPH (melanophilin)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl190,915,085 - 90,951,142 (+)Ensembl
GRCm38190,915,024 - 90,951,142 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37192,811,677 - 92,847,719 (+)NCBIGRCm37mm9NCBIm37
MGSCv36192,745,513 - 92,780,165 (+)NCBImm8
Celera193,860,662 - 93,896,365 (+)NCBICelera
Cytogenetic Map1 DNCBI
cM Map145.73NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Mlph
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1321809
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.