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Gene: DHRS2 (dehydrogenase/reductase 2) Homo sapiens
Symbol: DHRS2
Name: dehydrogenase/reductase 2
Description: Exhibits carbonyl reductase (NADPH) activity. Involved in several processes, including cellular response to oxidative stress; myeloid dendritic cell differentiation; and negative regulation of apoptotic process. Localizes to the mitochondrion; nuclear envelope; and nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: dehydrogenase/reductase (SDR family) member 2; dehydrogenase/reductase member 2; dehydrogenase/reductase SDR family member 2; dehydrogenase/reductase SDR family member 2, mitochondrial; dicarbonyl reductase HEP27; FLJ20338; HEP27; protein D; SDR25C1; short chain dehydrogenase/reductase family 25C member 1; short chain dehydrogenase/reductase family 25C, member 1; short-chain alcohol dehydrogenase family member
Mus musculus (house mouse) : Dhrs2 (dehydrogenase/reductase member 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Dhrs2 (dehydrogenase/reductase 2)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100976049 (dehydrogenase/reductase SDR family member 2, mitochondrial)
Canis lupus familiaris (dog) : DHRS2 (dehydrogenase/reductase 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1423,630,115 - 23,645,639 (+)Ensembl
GRCh381423,630,115 - 23,645,639 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371424,099,324 - 24,114,848 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361423,175,422 - 23,184,688 (+)NCBINCBI36hg18NCBI36
Build 341423,175,421 - 23,184,686NCBI
Celera143,968,304 - 3,977,579 (+)NCBI
Cytogenetic Map14q11.2NCBI
HuRef144,222,777 - 4,232,052 (+)NCBIHuRef
CHM1_11424,097,994 - 24,113,538 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on DHRS2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1321774
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-12-31
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.