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Gene: Kdm1b (lysine (K)-specific demethylase 1B) Mus musculus
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Symbol: Kdm1b
Name: lysine (K)-specific demethylase 1B
Description: Exhibits flavin adenine dinucleotide binding activity; histone demethylase activity (H3-K4 specific); and zinc ion binding activity. Involved in several processes, including DNA methylation involved in gamete generation; histone H3-K4 demethylation; and regulation of gene expression by genetic imprinting. Localizes to the nucleus. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human KDM1B (lysine demethylase 1B); PARTICIPATES IN histone modification pathway; INTERACTS WITH 1,1-dichloroethene; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4632428N09Rik; AI482520; amine oxidase, flavin containing 1; Aof1; flavin-containing amine oxidase domain-containing protein 1; lysine-specific histone demethylase 1B; lysine-specific histone demethylase 2; MGC38211
Orthologs:
Homo sapiens (human) : KDM1B (lysine demethylase 1B)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Kdm1b (lysine demethylase 1B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kdm1b (lysine demethylase 1B)
Pan paniscus (bonobo/pygmy chimpanzee) : KDM1B (lysine demethylase 1B)
Canis lupus familiaris (dog) : KDM1B (lysine demethylase 1B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kdm1b (lysine demethylase 1B)
Sus scrofa (pig) : KDM1B (lysine demethylase 1B)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1347,043,499 - 47,085,279 (+)Ensembl
GRCm381347,043,373 - 47,085,279 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371347,138,908 - 47,179,982 (+)NCBIGRCm37mm9NCBIm37
MGSCv361347,054,542 - 47,095,572 (+)NCBImm8
Celera1348,128,118 - 48,169,855 (+)NCBICelera
Cytogenetic Map13 A5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Kdm1b
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1321761
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.