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Gene: Kdm1b (lysine (K)-specific demethylase 1B) Mus musculus
Symbol: Kdm1b
Name: lysine (K)-specific demethylase 1B
Description: Exhibits flavin adenine dinucleotide binding activity; histone demethylase activity (H3-K4 specific); and zinc ion binding activity. Involved in several processes, including DNA methylation involved in gamete generation; histone H3-K4 demethylation; and regulation of gene expression by genetic imprinting. Localizes to the nucleus. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human KDM1B (lysine demethylase 1B); PARTICIPATES IN histone modification pathway; INTERACTS WITH 1,1-dichloroethene; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4632428N09Rik; AI482520; amine oxidase, flavin containing 1; Aof1; flavin-containing amine oxidase domain-containing protein 1; lysine-specific histone demethylase 1B; lysine-specific histone demethylase 2; MGC38211
Homo sapiens (human) : KDM1B (lysine demethylase 1B)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Kdm1b (lysine demethylase 1B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kdm1b (lysine demethylase 1B)
Pan paniscus (bonobo/pygmy chimpanzee) : KDM1B (lysine demethylase 1B)
Canis lupus familiaris (dog) : KDM1B (lysine demethylase 1B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kdm1b (lysine demethylase 1B)
Sus scrofa (pig) : KDM1B (lysine demethylase 1B)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1347,043,499 - 47,085,279 (+)Ensembl
GRCm381347,043,373 - 47,085,279 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371347,138,908 - 47,179,982 (+)NCBIGRCm37mm9NCBIm37
MGSCv361347,054,542 - 47,095,572 (+)NCBImm8
Celera1348,128,118 - 48,169,855 (+)NCBICelera
Cytogenetic Map13 A5NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Kdm1b
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1321761
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.