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Gene: APOH (apolipoprotein H) Homo sapiens
Symbol: APOH
Name: apolipoprotein H
Description: Exhibits identical protein binding activity; lipoprotein lipase activator activity; and phospholipid binding activity. Involved in several processes, including blood coagulation, intrinsic pathway; negative regulation of apoptotic process; and regulation of blood coagulation. Localizes to several cellular components, including the chylomicron; high-density lipoprotein particle; and very-low-density lipoprotein particle. Implicated in antiphospholipid syndrome; myocardial infarction; and peripheral vascular disease. Biomarker of arteriosclerosis; diabetes mellitus; diabetic retinopathy; macular retinal edema; and type 2 diabetes mellitus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: activated protein C-binding protein; anticardiolipin cofactor; APC inhibitor; apo-H; apolipoprotein H (beta-2-glycoprotein I); B2G1; B2GP1; B2GPI; beta(2)GPI; beta-2-glycoprotein 1; BG
Mus musculus (house mouse) : Apoh (apolipoprotein H)  MGI  Alliance
Rattus norvegicus (Norway rat) : Apoh (apolipoprotein H)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Apoh (apolipoprotein H)
Pan paniscus (bonobo/pygmy chimpanzee) : APOH (apolipoprotein H)
Canis lupus familiaris (dog) : APOH (apolipoprotein H)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Apoh (apolipoprotein H)
Sus scrofa (pig) : APOH (apolipoprotein H)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381766,212,033 - 66,229,415 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371764,208,147 - 64,225,556 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361761,638,609 - 61,656,018 (-)NCBINCBI36hg18NCBI36
Build 341761,638,613 - 61,655,992NCBI
Celera1760,780,183 - 60,797,591 (-)NCBI
Cytogenetic Map17q24.2NCBI
HuRef1759,599,926 - 59,617,004 (-)NCBIHuRef
CHM1_11764,272,419 - 64,289,828 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on APOH
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1321637
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.