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Gene: APOH (apolipoprotein H) Homo sapiens
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Symbol: APOH
Name: apolipoprotein H
Description: Exhibits identical protein binding activity; lipoprotein lipase activator activity; and phospholipid binding activity. Involved in several processes, including blood coagulation, intrinsic pathway; negative regulation of apoptotic process; and regulation of blood coagulation. Localizes to several cellular components, including the chylomicron; high-density lipoprotein particle; and very-low-density lipoprotein particle. Implicated in antiphospholipid syndrome; myocardial infarction; and peripheral vascular disease. Biomarker of arteriosclerosis; diabetes mellitus; diabetic retinopathy; macular retinal edema; and type 2 diabetes mellitus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: activated protein C-binding protein; anticardiolipin cofactor; APC inhibitor; apo-H; apolipoprotein H (beta-2-glycoprotein I); B2G1; B2GP1; B2GPI; beta(2)GPI; beta-2-glycoprotein 1; BG
Orthologs:
Mus musculus (house mouse) : Apoh (apolipoprotein H)  MGI  Alliance
Rattus norvegicus (Norway rat) : Apoh (apolipoprotein H)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Apoh (apolipoprotein H)
Pan paniscus (bonobo/pygmy chimpanzee) : APOH (apolipoprotein H)
Canis lupus familiaris (dog) : APOH (apolipoprotein H)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Apoh (apolipoprotein H)
Sus scrofa (pig) : APOH (apolipoprotein H)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381766,212,033 - 66,229,415 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371764,208,147 - 64,225,556 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361761,638,609 - 61,656,018 (-)NCBINCBI36hg18NCBI36
Build 341761,638,613 - 61,655,992NCBI
Celera1760,780,183 - 60,797,591 (-)NCBI
Cytogenetic Map17q24.2NCBI
HuRef1759,599,926 - 59,617,004 (-)NCBIHuRef
CHM1_11764,272,419 - 64,289,828 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on APOH
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1321637
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.