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Gene: NUBP1 (NUBP iron-sulfur cluster assembly factor 1, cytosolic) Homo sapiens

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Symbol:

NUBP1

Name:

NUBP iron-sulfur cluster assembly factor 1, cytosolic

RGD ID:

1321458

HGNC Page

HGNC:8041

Description:

Enables iron-sulfur cluster binding activity. Involved in intracellular iron ion homeostasis; iron-sulfur cluster assembly; and regulation of cell growth. Located in cytosol and plasma membrane.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

CIAO5; cytosolic Fe-S cluster assembly factor NUBP1; MGC117406; MGC130052; MGC130053; NBP; NBP 1; NBP1; NBP35; nucleotide binding protein (e.coli MinD like); nucleotide binding protein 1; nucleotide binding protein 1 (E.coli MinD like); nucleotide binding protein 1 (MinD homolog, E. coli); nucleotide-binding protein 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Allele / Splice:

See ClinVar data

Latest Assembly:

GRCh38 - Human Genome Assembly GRCh38

Position:

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	16	10,743,842 - 10,769,351 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	16	10,743,786 - 10,769,351 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	16	10,837,699 - 10,863,208 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	16	10,745,199 - 10,770,709 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	16	10,745,217 - 10,770,709	NCBI
Celera	16	11,007,059 - 11,032,475 (+)	NCBI		Celera
Cytogenetic Map	16	p13.13	NCBI
HuRef	16	10,756,412 - 10,781,588 (+)	NCBI		HuRef
CHM1_1	16	10,837,712 - 10,863,204 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	16	10,779,762 - 10,805,269 (+)	NCBI		T2T-CHM13v2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Charcot-Marie-Tooth disease type 1C (IAGP)

Landau-Kleffner syndrome (IAGP)

MHC class II deficiency (IAGP)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (EXP)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,4,6-trinitrotoluene (ISO)

3-chloropropane-1,2-diol (ISO)

4-hydroxyphenyl retinamide (ISO)

6-propyl-2-thiouracil (ISO)

amitrole (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenous acid (EXP)

benzo[a]pyrene (ISO)

bisphenol A (ISO)

cadmium atom (EXP)

cadmium dichloride (EXP)

caffeine (EXP)

carbon nanotube (ISO)

CGP 52608 (EXP)

chromium(6+) (EXP)

copper atom (EXP)

copper(0) (EXP)

diarsenic trioxide (EXP)

dibutyl phthalate (ISO)

dioxygen (ISO)

disulfiram (EXP)

FR900359 (EXP)

gentamycin (ISO)

ivermectin (EXP)

lead(0) (EXP)

methimazole (ISO)

nickel atom (EXP)

ozone (EXP)

paracetamol (ISO)

pirinixic acid (ISO)

potassium chromate (EXP)

propiconazole (ISO)

pyrogallol (ISO)

resveratrol (EXP)

SB 431542 (EXP)

Soman (ISO)

sulfadimethoxine (ISO)

tetrachloromethane (ISO)

thapsigargin (ISO)

titanium dioxide (ISO)

trichloroethene (ISO)

trichostatin A (EXP)

triptonide (ISO)

tungsten (ISO)

urethane (EXP)

valproic acid (ISO)

vinclozolin (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell projection organization (IEA)

centrosome localization (IEA,ISO)

intracellular iron ion homeostasis (IMP)

iron-sulfur cluster assembly (IBA,IEA,IMP)

negative regulation of centrosome duplication (IEA,ISO)

protein localization to cell cortex (IEA,ISO)

regulation of cell growth (IMP)

Cellular Component

cell projection (IEA)

centriole (IEA)

centrosome (IEA)

cilium (IEA)

cytoplasm (IEA)

cytoskeleton (IEA)

cytosol (IBA,IDA)

nucleus (IEA)

plasma membrane (IDA)

Molecular Function

4 iron, 4 sulfur cluster binding (IEA)

ATP binding (IEA)

ATP hydrolysis activity (IEA)

ATP-dependent FeS chaperone activity (IEA)

iron-sulfur cluster binding (IBA,IDA,IEA)

metal ion binding (IEA)

nucleotide binding (TAS)

protein binding (IPI)

Molecular Pathway Annotations Click to see Annotation Detail View

cytosolic iron-sulfur cluster protein assembly pathway (TAS)

References

References - curated

#	Reference Title	Reference Citation
1.	GOAs Human GO annotations	GOA_HUMAN data from the GO Consortium
2.	Iron-sulfur cluster biogenesis in mammalian cells: New insights into the molecular mechanisms of cluster delivery.	Maio N and Rouault TA, Biochim Biophys Acta. 2015 Jun;1853(6):1493-512. doi: 10.1016/j.bbamcr.2014.09.009. Epub 2014 Sep 19.
3.	Biogenesis of cytosolic and nuclear iron-sulfur proteins and their role in genome stability.	Paul VD and Lill R, Biochim Biophys Acta. 2015 Jun;1853(6):1528-39. doi: 10.1016/j.bbamcr.2014.12.018. Epub 2015 Jan 10.
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:7926816	PMID:8125298	PMID:10486206	PMID:10915798	PMID:12477932	PMID:15342556	PMID:18029348	PMID:18573874	PMID:18676680	PMID:19170196	PMID:19625176	PMID:21873635
PMID:21900206	PMID:22863883	PMID:22939629	PMID:23376485	PMID:25648896	PMID:26186194	PMID:26344197	PMID:26972000	PMID:28514442	PMID:28515276	PMID:28718761	PMID:30033366
PMID:31091453	PMID:32429669	PMID:33961781	PMID:34226595	PMID:34373451	PMID:35563538	PMID:35831314	PMID:35944360	PMID:36114006	PMID:36215168	PMID:36629882	PMID:36652389
PMID:36916754	PMID:37024974	PMID:37866880	PMID:38113892

Genomics

Comparative Map Data

NUBP1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	16	10,743,842 - 10,769,351 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	16	10,743,786 - 10,769,351 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	16	10,837,699 - 10,863,208 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	16	10,745,199 - 10,770,709 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	16	10,745,217 - 10,770,709	NCBI
Celera	16	11,007,059 - 11,032,475 (+)	NCBI		Celera
Cytogenetic Map	16	p13.13	NCBI
HuRef	16	10,756,412 - 10,781,588 (+)	NCBI		HuRef
CHM1_1	16	10,837,712 - 10,863,204 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	16	10,779,762 - 10,805,269 (+)	NCBI		T2T-CHM13v2.0

Nubp1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	16	10,229,802 - 10,242,317 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	16	10,229,812 - 10,242,292 (+)	Ensembl		GRCm39 Ensembl
GRCm38	16	10,411,884 - 10,424,453 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	16	10,411,948 - 10,424,428 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	16	10,412,031 - 10,424,521 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	16	10,325,553 - 10,337,109 (+)	NCBI		MGSCv36	mm8
Celera	16	11,045,448 - 11,057,938 (+)	NCBI		Celera
Cytogenetic Map	16	A1	NCBI
cM Map	16	5.61	NCBI

Nubp1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	5,766,157 - 5,777,648 (-)	NCBI		GRCr8
mRatBN7.2	10	5,259,328 - 5,270,848 (-)	NCBI	mRatBN7.2	mRatBN7.2
UTH_Rnor_SHR_Utx	10	9,955,670 - 9,967,161 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	9,476,783 - 9,488,274 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	5,115,152 - 5,126,642 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	5,333,378 - 5,343,949 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	5,333,378 - 5,344,121 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	4,155,446 - 4,166,017 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	5,206,634 - 5,217,205 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	5,206,633 - 5,217,205 (-)	NCBI
Celera	10	4,276,872 - 4,287,443 (-)	NCBI		Celera
Cytogenetic Map	10	q11	NCBI

Nubp1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955442	7,717,422 - 7,732,496 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955442	7,717,422 - 7,732,496 (-)	NCBI	ChiLan1.0	ChiLan1.0

NUBP1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	18	11,236,566 - 11,315,874 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	16	15,012,495 - 15,091,492 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	16	9,681,800 - 9,708,673 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	16	10,906,347 - 10,931,799 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	16	10,906,719 - 10,931,800 (+)	Ensembl	panpan1.1		panPan2

NUBP1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	31,900,540 - 31,922,087 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	31,896,596 - 31,921,989 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	33,282,660 - 33,304,486 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	32,082,705 - 32,104,573 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	6	32,081,940 - 32,104,479 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	6	31,896,734 - 31,918,569 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	31,770,561 - 31,792,362 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	32,194,799 - 32,216,643 (-)	NCBI		UU_Cfam_GSD_1.0

Nubp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	111,126,784 - 111,140,480 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936530	8,971,380 - 8,986,033 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936530	8,970,963 - 8,985,925 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NUBP1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	32,311,779 - 32,340,034 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	32,311,774 - 32,340,120 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	33,045,133 - 33,072,061 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

NUBP1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	10,224,965 - 10,248,328 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	5	10,225,173 - 10,249,047 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666068	19,923,874 - 19,947,229 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Nubp1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624824	8,024,575 - 8,040,364 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624824	8,024,459 - 8,040,353 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in NUBP1
35 total Variants

Clinical Variants

Name	Type	Condition(s)	Position(s)	Clinical significance
GRCh38/hg38 16p13.3-13.13(chr16:23141-11296695)x3	copy number gain	See cases [RCV000052367]	Chr16:23141..11296695 [GRCh38] Chr16:73141..11390552 [GRCh37] Chr16:13141..11298053 [NCBI36] Chr16:16p13.3-13.13	pathogenic
GRCh38/hg38 16p13.3-13.13(chr16:4536131-10852466)x1	copy number loss	Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053274]\|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053274]\|See cases [RCV000053274]	Chr16:4536131..10852466 [GRCh38] Chr16:4586132..10946323 [GRCh37] Chr16:4526133..10853824 [NCBI36] Chr16:16p13.3-13.13	pathogenic
NM_002484.3(NUBP1):c.748G>C (p.Gly250Arg)	single nucleotide variant	Malignant melanoma [RCV000070981]	Chr16:10761787 [GRCh38] Chr16:10855644 [GRCh37] Chr16:10763145 [NCBI36] Chr16:16p13.13	not provided
NM_002484.3(NUBP1):c.602C>T (p.Pro201Leu)	single nucleotide variant	Malignant melanoma [RCV000062961]	Chr16:10758023 [GRCh38] Chr16:10851880 [GRCh37] Chr16:10759381 [NCBI36] Chr16:16p13.13	not provided
NM_002484.4(NUBP1):c.691A>C (p.Ser231Arg)	single nucleotide variant	not specified [RCV004283088]	Chr16:10761448 [GRCh38] Chr16:10855305 [GRCh37] Chr16:16p13.13	uncertain significance
GRCh38/hg38 16p13.3-11.2(chr16:4644892-29170820)x3	copy number gain	See cases [RCV000133809]	Chr16:4644892..29170820 [GRCh38] Chr16:4694893..29182141 [GRCh37] Chr16:4634894..29089642 [NCBI36] Chr16:16p13.3-11.2	pathogenic
GRCh38/hg38 16p13.3-13.13(chr16:46766-11525516)x3	copy number gain	See cases [RCV000133780]	Chr16:46766..11525516 [GRCh38] Chr16:96766..11619372 [GRCh37] Chr16:36766..11526873 [NCBI36] Chr16:16p13.3-13.13	pathogenic
GRCh38/hg38 16p13.3-13.12(chr16:43732-13326806)x3	copy number gain	See cases [RCV000139166]	Chr16:43732..13326806 [GRCh38] Chr16:93732..13420663 [GRCh37] Chr16:33732..13328164 [NCBI36] Chr16:16p13.3-13.12	pathogenic
GRCh38/hg38 16p13.13(chr16:10560475-10775716)x1	copy number loss	See cases [RCV000141955]	Chr16:10560475..10775716 [GRCh38] Chr16:10654332..10869573 [GRCh37] Chr16:10561833..10777074 [NCBI36] Chr16:16p13.13	uncertain significance
GRCh38/hg38 16p13.3-13.11(chr16:666662-15743104)x3	copy number gain	See cases [RCV000143710]	Chr16:666662..15743104 [GRCh38] Chr16:716662..15836961 [GRCh37] Chr16:656663..15744462 [NCBI36] Chr16:16p13.3-13.11	pathogenic
GRCh37/hg19 16p13.3-11.2(chr16:102839-28327676)x3	copy number gain	See cases [RCV000203445]	Chr16:102839..28327676 [GRCh37] Chr16:16p13.3-11.2	pathogenic
GRCh37/hg19 16p13.3-11.2(chr16:1279324-31926800)x3	copy number gain	Breast ductal adenocarcinoma [RCV000207053]	Chr16:1279324..31926800 [GRCh37] Chr16:16p13.3-11.2	uncertain significance
GRCh37/hg19 16p13.3-12.3(chr16:1274615-19073133)x3	copy number gain	Breast ductal adenocarcinoma [RCV000207326]	Chr16:1274615..19073133 [GRCh37] Chr16:16p13.3-12.3	uncertain significance
NM_002484.4(NUBP1):c.591C>G (p.Ile197Met)	single nucleotide variant	not specified [RCV004311584]	Chr16:10758012 [GRCh38] Chr16:10851869 [GRCh37] Chr16:16p13.13	uncertain significance
GRCh37/hg19 16p13.3-q24.3(chr16:69193-90274381)x3	copy number gain	See cases [RCV000446684]	Chr16:69193..90274381 [GRCh37] Chr16:16p13.3-q24.3	pathogenic
GRCh37/hg19 16p13.2-13.13(chr16:9631472-12128275)x3	copy number gain	See cases [RCV000511571]	Chr16:9631472..12128275 [GRCh37] Chr16:16p13.2-13.13	uncertain significance
GRCh37/hg19 16p13.2-q24.3(chr16:9273328-89548493)x3	copy number gain	See cases [RCV000511622]	Chr16:9273328..89548493 [GRCh37] Chr16:16p13.2-q24.3	uncertain significance
GRCh37/hg19 16p13.13(chr16:10519916-11249329)x3	copy number gain	See cases [RCV000511543]	Chr16:10519916..11249329 [GRCh37] Chr16:16p13.13	likely benign\|uncertain significance
maternal UPD(16p)	complex	Hemimegalencephaly [RCV000494707]	Chr16:1280042..33710558 [GRCh37] Chr16:16p13.3-11.2	pathogenic
GRCh37/hg19 16p13.3-q24.3(chr16:85881-90155062)	copy number gain	See cases [RCV000511296]	Chr16:85881..90155062 [GRCh37] Chr16:16p13.3-q24.3	pathogenic
GRCh37/hg19 16p13.3-12.2(chr16:85880-22442007)x3	copy number gain	See cases [RCV000511360]	Chr16:85880..22442007 [GRCh37] Chr16:16p13.3-12.2	pathogenic
GRCh37/hg19 16p13.3-q24.3(chr16:85881-90155062)x3	copy number gain	See cases [RCV000512138]	Chr16:85881..90155062 [GRCh37] Chr16:16p13.3-q24.3	pathogenic
NM_002484.4(NUBP1):c.107G>C (p.Gly36Ala)	single nucleotide variant	not specified [RCV004321821]	Chr16:10744048 [GRCh38] Chr16:10837905 [GRCh37] Chr16:16p13.13	uncertain significance
GRCh37/hg19 16p13.3-12.3(chr16:85880-19806921)x3	copy number gain	See cases [RCV000512194]	Chr16:85880..19806921 [GRCh37] Chr16:16p13.3-12.3	pathogenic
GRCh37/hg19 16p13.2-13.13(chr16:9321032-10971457)x3	copy number gain	See cases [RCV000512306]	Chr16:9321032..10971457 [GRCh37] Chr16:16p13.2-13.13	uncertain significance
GRCh37/hg19 16p13.3-13.13(chr16:85880-11209288)x3	copy number gain	not provided [RCV000683743]	Chr16:85880..11209288 [GRCh37] Chr16:16p13.3-13.13	pathogenic
GRCh37/hg19 16p13.13(chr16:10529891-11889585)x3	copy number gain	not provided [RCV000683759]	Chr16:10529891..11889585 [GRCh37] Chr16:16p13.13	uncertain significance
GRCh37/hg19 16p13.3-q24.3(chr16:88165-90163275)x3	copy number gain	not provided [RCV000738917]	Chr16:88165..90163275 [GRCh37] Chr16:16p13.3-q24.3	pathogenic
GRCh37/hg19 16p13.3-q24.3(chr16:88165-90274695)x3	copy number gain	not provided [RCV000738918]	Chr16:88165..90274695 [GRCh37] Chr16:16p13.3-q24.3	pathogenic
GRCh37/hg19 16p13.3-q24.3(chr16:61451-90294632)x3	copy number gain	not provided [RCV000738915]	Chr16:61451..90294632 [GRCh37] Chr16:16p13.3-q24.3	pathogenic
GRCh37/hg19 16p13.13(chr16:10563055-10958954)x1	copy number loss	not provided [RCV000849090]	Chr16:10563055..10958954 [GRCh37] Chr16:16p13.13	pathogenic
GRCh37/hg19 16p13.2-13.13(chr16:10196800-11037738)x1	copy number loss	not provided [RCV000845661]	Chr16:10196800..11037738 [GRCh37] Chr16:16p13.2-13.13	pathogenic
NM_002484.4(NUBP1):c.914A>G (p.Glu305Gly)	single nucleotide variant	not specified [RCV004303510]	Chr16:10769056 [GRCh38] Chr16:10862913 [GRCh37] Chr16:16p13.13	uncertain significance
NC_000016.9:g.(?_8829597)_(11683693_?)dup	duplication	Landau-Kleffner syndrome [RCV003105356]	Chr16:8829597..11683693 [GRCh37] Chr16:16p13.2-13.13	uncertain significance
GRCh37/hg19 16p13.3-11.2(chr16:4380767-30445350)x3	copy number gain	not provided [RCV002472599]	Chr16:4380767..30445350 [GRCh37] Chr16:16p13.3-11.2	pathogenic
GRCh37/hg19 16p13.3-11.2(chr16:5805001-34230001)	copy number gain	Microcephaly [RCV001252948]	Chr16:5805001..34230001 [GRCh37] Chr16:16p13.3-11.2	pathogenic
GRCh37/hg19 16p13.3-11.2(chr16:2959279-30190593)x3	copy number gain	See cases [RCV001263169]	Chr16:2959279..30190593 [GRCh37] Chr16:16p13.3-11.2	pathogenic\|likely pathogenic
NC_000016.9:g.(?_8829597)_(11650586_?)dup	duplication	Charcot-Marie-Tooth disease type 1C [RCV003120793]\|MHC class II deficiency [RCV002000309]	Chr16:8829597..11650586 [GRCh37] Chr16:16p13.2-13.13	uncertain significance
NC_000016.9:g.(?_10637407)_(10971259_?)del	deletion	MHC class II deficiency [RCV003122222]	Chr16:10637407..10971259 [GRCh37] Chr16:16p13.13	pathogenic
NM_002484.4(NUBP1):c.80A>G (p.Asn27Ser)	single nucleotide variant	not specified [RCV004297234]	Chr16:10744021 [GRCh38] Chr16:10837878 [GRCh37] Chr16:16p13.13	uncertain significance
GRCh37/hg19 16p13.2-13.13(chr16:10423631-12176517)x3	copy number gain	not provided [RCV002474875]	Chr16:10423631..12176517 [GRCh37] Chr16:16p13.2-13.13	uncertain significance
NM_002484.4(NUBP1):c.287G>A (p.Gly96Glu)	single nucleotide variant	not specified [RCV004239274]	Chr16:10752638 [GRCh38] Chr16:10846495 [GRCh37] Chr16:16p13.13	uncertain significance
NM_002484.4(NUBP1):c.490G>A (p.Glu164Lys)	single nucleotide variant	not specified [RCV004237589]	Chr16:10757911 [GRCh38] Chr16:10851768 [GRCh37] Chr16:16p13.13	uncertain significance
NM_002484.4(NUBP1):c.754G>A (p.Ala252Thr)	single nucleotide variant	not specified [RCV004228847]	Chr16:10761793 [GRCh38] Chr16:10855650 [GRCh37] Chr16:16p13.13	uncertain significance
NM_002484.4(NUBP1):c.230A>G (p.His77Arg)	single nucleotide variant	not specified [RCV004216140]	Chr16:10747248 [GRCh38] Chr16:10841105 [GRCh37] Chr16:16p13.13	uncertain significance
NM_002484.4(NUBP1):c.854T>G (p.Ile285Ser)	single nucleotide variant	not specified [RCV004187126]	Chr16:10767982 [GRCh38] Chr16:10861839 [GRCh37] Chr16:16p13.13	uncertain significance
NM_002484.4(NUBP1):c.446A>G (p.Lys149Arg)	single nucleotide variant	not specified [RCV004151788]	Chr16:10756775 [GRCh38] Chr16:10850632 [GRCh37] Chr16:16p13.13	uncertain significance
NM_002484.4(NUBP1):c.809A>G (p.Asp270Gly)	single nucleotide variant	not specified [RCV004161323]	Chr16:10761848 [GRCh38] Chr16:10855705 [GRCh37] Chr16:16p13.13	uncertain significance
NM_002484.4(NUBP1):c.752G>A (p.Gly251Asp)	single nucleotide variant	not specified [RCV004157796]	Chr16:10761791 [GRCh38] Chr16:10855648 [GRCh37] Chr16:16p13.13	uncertain significance
NM_002484.4(NUBP1):c.854T>C (p.Ile285Thr)	single nucleotide variant	not specified [RCV004164833]	Chr16:10767982 [GRCh38] Chr16:10861839 [GRCh37] Chr16:16p13.13	uncertain significance
NM_002484.4(NUBP1):c.690G>C (p.Met230Ile)	single nucleotide variant	not specified [RCV004135575]	Chr16:10761447 [GRCh38] Chr16:10855304 [GRCh37] Chr16:16p13.13	uncertain significance
NM_002484.4(NUBP1):c.311G>A (p.Gly104Glu)	single nucleotide variant	not specified [RCV004125790]	Chr16:10752662 [GRCh38] Chr16:10846519 [GRCh37] Chr16:16p13.13	uncertain significance
NM_002484.4(NUBP1):c.733T>A (p.Phe245Ile)	single nucleotide variant	not specified [RCV004323323]	Chr16:10761772 [GRCh38] Chr16:10855629 [GRCh37] Chr16:16p13.13	uncertain significance
NM_002484.4(NUBP1):c.296T>G (p.Ile99Ser)	single nucleotide variant	not specified [RCV004353279]	Chr16:10752647 [GRCh38] Chr16:10846504 [GRCh37] Chr16:16p13.13	uncertain significance
NM_002484.4(NUBP1):c.10G>T (p.Val4Leu)	single nucleotide variant	not specified [RCV004355321]	Chr16:10743873 [GRCh38] Chr16:10837730 [GRCh37] Chr16:16p13.13	uncertain significance
NM_002484.4(NUBP1):c.781G>A (p.Val261Ile)	single nucleotide variant	not specified [RCV004359778]	Chr16:10761820 [GRCh38] Chr16:10855677 [GRCh37] Chr16:16p13.13	likely benign
NM_002484.4(NUBP1):c.164A>G (p.His55Arg)	single nucleotide variant	not specified [RCV004365394]	Chr16:10747182 [GRCh38] Chr16:10841039 [GRCh37] Chr16:16p13.13	uncertain significance
GRCh37/hg19 16p13.13(chr16:10671445-10864286)x1	copy number loss	not provided [RCV003483270]	Chr16:10671445..10864286 [GRCh37] Chr16:16p13.13	uncertain significance
NM_002484.4(NUBP1):c.753C>T (p.Gly251=)	single nucleotide variant	not provided [RCV003411266]	Chr16:10761792 [GRCh38] Chr16:10855649 [GRCh37] Chr16:16p13.13	likely benign
NM_002484.4(NUBP1):c.303G>A (p.Lys101=)	single nucleotide variant	not provided [RCV003417643]	Chr16:10752654 [GRCh38] Chr16:10846511 [GRCh37] Chr16:16p13.13	likely benign
NM_002484.4(NUBP1):c.274A>G (p.Ile92Val)	single nucleotide variant	not specified [RCV004496090]	Chr16:10752625 [GRCh38] Chr16:10846482 [GRCh37] Chr16:16p13.13	uncertain significance
NM_002484.4(NUBP1):c.213C>A (p.Phe71Leu)	single nucleotide variant	not specified [RCV004496089]	Chr16:10747231 [GRCh38] Chr16:10841088 [GRCh37] Chr16:16p13.13	uncertain significance
NM_002484.4(NUBP1):c.38G>C (p.Ser13Thr)	single nucleotide variant	not specified [RCV004496091]	Chr16:10743979 [GRCh38] Chr16:10837836 [GRCh37] Chr16:16p13.13	uncertain significance
NM_002484.4(NUBP1):c.772G>C (p.Asp258His)	single nucleotide variant	not specified [RCV004496096]	Chr16:10761811 [GRCh38] Chr16:10855668 [GRCh37] Chr16:16p13.13	uncertain significance
NM_002484.4(NUBP1):c.94G>C (p.Ala32Pro)	single nucleotide variant	not specified [RCV004496097]	Chr16:10744035 [GRCh38] Chr16:10837892 [GRCh37] Chr16:16p13.13	uncertain significance
NM_002484.4(NUBP1):c.575T>C (p.Ile192Thr)	single nucleotide variant	not specified [RCV004496094]	Chr16:10757996 [GRCh38] Chr16:10851853 [GRCh37] Chr16:16p13.13	uncertain significance
NM_002484.4(NUBP1):c.436G>A (p.Gly146Arg)	single nucleotide variant	not specified [RCV004496092]	Chr16:10756765 [GRCh38] Chr16:10850622 [GRCh37] Chr16:16p13.13	uncertain significance
NM_002484.4(NUBP1):c.545C>T (p.Ser182Leu)	single nucleotide variant	not specified [RCV004496093]	Chr16:10757966 [GRCh38] Chr16:10851823 [GRCh37] Chr16:16p13.13	uncertain significance
NM_002484.4(NUBP1):c.154A>C (p.Thr52Pro)	single nucleotide variant	not specified [RCV004496088]	Chr16:10747172 [GRCh38] Chr16:10841029 [GRCh37] Chr16:16p13.13	uncertain significance
NM_002484.4(NUBP1):c.907A>T (p.Ile303Phe)	single nucleotide variant	not specified [RCV004652601]	Chr16:10769049 [GRCh38] Chr16:10862906 [GRCh37] Chr16:16p13.13	uncertain significance
NM_002484.4(NUBP1):c.883G>C (p.Ala295Pro)	single nucleotide variant	not specified [RCV004638815]	Chr16:10768011 [GRCh38] Chr16:10861868 [GRCh37] Chr16:16p13.13	uncertain significance
NM_002484.4(NUBP1):c.338G>A (p.Ser113Asn)	single nucleotide variant	not specified [RCV004652602]	Chr16:10755731 [GRCh38] Chr16:10849588 [GRCh37] Chr16:16p13.13	uncertain significance
NM_002484.4(NUBP1):c.56G>T (p.Gly19Val)	single nucleotide variant	not specified [RCV004652603]	Chr16:10743997 [GRCh38] Chr16:10837854 [GRCh37] Chr16:16p13.13	uncertain significance

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	1609
Count of miRNA genes:	673
Interacting mature miRNAs:	786
Transcripts:	ENST00000283027, ENST00000433392, ENST00000571175, ENST00000571790, ENST00000573663, ENST00000574137, ENST00000574334, ENST00000574691
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCh38)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
407416264	GWAS1065240_H	aspartate aminotransferase measurement QTL GWAS1065240 (human)		3e-11	aspartate aminotransferase measurement	blood aspartate aminotransferase activity level (CMO:0000580)	16	10762254	10762255	Human
407049732	GWAS698708_H	phosphoglyceric acid measurement QTL GWAS698708 (human)		0.000003	phosphoglyceric acid measurement		16	10768057	10768058	Human

Markers in Region

RH103742

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	16	10,843,427 - 10,843,577	UniSTS	GRCh37
Build 36	16	10,750,928 - 10,751,078	RGD	NCBI36
Celera	16	11,012,800 - 11,012,950	RGD
Cytogenetic Map	16	p13.13	UniSTS
HuRef	16	10,762,196 - 10,762,346	UniSTS
GeneMap99-GB4 RH Map	16	99.54	UniSTS

D16S2962

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	16	10,862,966 - 10,863,199	UniSTS	GRCh37
Build 36	16	10,770,467 - 10,770,700	RGD	NCBI36
Celera	16	11,032,233 - 11,032,466	RGD
Cytogenetic Map	16	p13.13	UniSTS
HuRef	16	10,781,346 - 10,781,579	UniSTS
TNG Radiation Hybrid Map	16	5289.0	UniSTS
Stanford-G3 RH Map	16	524.0	UniSTS
GeneMap99-GB4 RH Map	16	98.92	UniSTS
Whitehead-RH Map	16	57.2	UniSTS
Whitehead-YAC Contig Map	16		UniSTS
NCBI RH Map	16	120.8	UniSTS
GeneMap99-G3 RH Map	16	484.0	UniSTS

240WE5

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	16	10,842,893 - 10,843,091	UniSTS	GRCh37
Build 36	16	10,750,394 - 10,750,592	RGD	NCBI36
Celera	16	11,012,254 - 11,012,464	RGD
Cytogenetic Map	16	p13.13	UniSTS
HuRef	16	10,761,662 - 10,761,860	UniSTS
Whitehead-YAC Contig Map	16		UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	entire extraembryonic component	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	pharyngeal arch	renal system	reproductive system	respiratory system	sensory system	visual system
1204	2439	2788	2253	4974	1726	2351	6	624	1951	465	2270	7306	6472	53	3734	1	852	1744	1617	175	1

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001278506	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001323594	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001323595	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001323596	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001323597	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_002484	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017023252	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_047434170	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_054380401	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC074136	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK223204	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK307148	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK310089	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC100290	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC109322	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC109323	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BP216107	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BP225034	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH471112	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CP068262	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KC877580	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U01833	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENST00000283027 ⟹ ENSP00000283027

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	16	10,743,842 - 10,769,351 (+)	Ensembl

Ensembl Acc Id:

ENST00000433392 ⟹ ENSP00000409654

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	16	10,743,855 - 10,769,351 (+)	Ensembl

Ensembl Acc Id:

ENST00000571175 ⟹ ENSP00000460288

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	16	10,757,873 - 10,769,351 (+)	Ensembl

Ensembl Acc Id:

ENST00000571790

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	16	10,743,841 - 10,763,834 (+)	Ensembl

Ensembl Acc Id:

ENST00000573663

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	16	10,765,024 - 10,769,313 (+)	Ensembl

Ensembl Acc Id:

ENST00000574137

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	16	10,743,844 - 10,762,112 (+)	Ensembl

Ensembl Acc Id:

ENST00000574334 ⟹ ENSP00000461746

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	16	10,743,786 - 10,757,994 (+)	Ensembl

Ensembl Acc Id:

ENST00000574691 ⟹ ENSP00000461723

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	16	10,758,011 - 10,769,351 (+)	Ensembl

RefSeq Acc Id:

NM_001278506 ⟹ NP_001265435

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	16	10,743,842 - 10,769,351 (+)	NCBI
GRCh37	16	10,837,643 - 10,863,208 (+)	NCBI
HuRef	16	10,756,412 - 10,781,588 (+)	NCBI
CHM1_1	16	10,837,712 - 10,863,204 (+)	NCBI
T2T-CHM13v2.0	16	10,779,762 - 10,805,269 (+)	NCBI

Sequence:

show sequence

CGAAGGCGGCAAAGGCGACGGAATGGAGGAGGTGCCTCACGACTGTCCAGGGGCCGACAGCGCC
CAGGCGGGCAGAGGGGCTTCATGTCAGGGATGCCCCAACCAGCGGCTGTGCGCTTCTGGAGCGG
GGGCCACTCCGGACACGGCTATAGAGGAAATCAAAGAGAAAATGAAGACTGTAAAACACAAAAT
CTTGGTATTGTCTGGGAAAGGCGGTGTTGGGAAAAGCACATTCAGCGCCCACCTTGCCCATGGC
CTAGCAGAGGATGAAAACACACAGATTGCTCTTCTAGACATCGATATATGTGGGCCATCGATTC
CCAAGATAATGGGATTGGAAGGAGAGCAGTACGTGGAAGACAACCTGGGGGTGATGTCAGTGGG
CTTCCTGCTCAGCAGTCCTGATGATGCTGTTATCTGGAGGGGACCCAAGAAAAACGGCATGATC
AAGCAGTTCCTCCGAGATGTGGACTGGGGAGAGGTCGACTACCTCATTGTGGACACCCCACCTG
GGACGTCGGATGAACACCTCTCGGTCGTCCGGTACCTGGCCACAGCACACATCGATGGAGCAGT
GATCATCACCACTCCCCAGGAGGTGTCACTCCAGGATGTCCGGAAAGAAATCAACTTCTGCCGC
AAGGTGAAGCTGCCCATCATCGGGGTGGTGGAGAACATGAGTGGCTTCATCTGTCCTAAGTGCA
AGAAAGAATCTCAGATATTCCCTCCCACAACCGGGGGCGCGGAGCTCATGTGCCAGGACTTGGA
GGTCCCTCTCCTCGGCAGAGTGCCCCTGGATCCGCTCATAGGTAAGAATTGTGACAAAGGCCAG
TCTTTTTTCATTGACGCCCCAGATTCCCCAGCCACGTTAGCCTACAGAAGTATAATTCAGAGAA
TCCAAGAGTTTTGTAATCTCCATCAGTCAAAAGAAGAGAACCTCATCAGTTCCTGAAACGAGAG
AATGTTCAGGACCAAGCAGTTACCGAGCGAGGCACTCACTGGGCAGCACATCCAGCCAGACCCG
ACCAGCTCCGGGATGGGGTGGGTCACAGCAAAAGGACCAGATGCTGGTGTGGTCCGAAGCCACT
TTCTCAGAGACACTTTAATCATTGAGTATTTGTACACTTTTCTTTAGAACATATATAAAGGGCA
TTCTCTACAAATGTGCCGTTTTAAGAATAAAACCCCCTCAAATCTC

hide sequence

RefSeq Acc Id:

NM_001323594 ⟹ NP_001310523

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	16	10,743,842 - 10,769,351 (+)	NCBI
CHM1_1	16	10,837,782 - 10,863,204 (+)	NCBI
T2T-CHM13v2.0	16	10,779,762 - 10,805,269 (+)	NCBI

Sequence:

show sequence

CGAAGGCGGCAAAGGCGACGGAATGGAGGAGGTGCCTCACGACTGTCCAGGGGCCGACAGCGCC
CAGGCGGGCAGAGGGGCTTCATGTCAGGGATGCCCCAACCAGCGGCTGTGCGCTTCTGGAGCGG
GGGCCACTCCGGACACGGCTATAGAGGAAATCAAAGAGAAAATGAAGACTGTAAAACACAAAAT
CTTGGTATTGTCTGGGAAAGGCGGTGTTGGGAAAAGCACATTCAGCGCCCACCTTGCCCATGGC
CTAGCAGAGGATGAAAACACACAGGTTCACCAGAGTGGCTCAGGCTGGTCTCCAGTGTACGTGG
AAGACAACCTGGGGGTGATGTCAGTGGGCTTCCTGCTCAGCAGTCCTGATGATGCTGTTATCTG
GAGGGGACCCAAGAAAAACGGCATGATCAAGCAGTTCCTCCGAGATGTGGACTGGGGAGAGGTC
GACTACCTCATTGTGGACACCCCACCTGGGACGTCGGATGAACACCTCTCGGTCGTCCGGTACC
TGGCCACAGCACACATCGATGGAGCAGTGATCATCACCACTCCCCAGGAGGTGTCACTCCAGGA
TGTCCGGAAAGAAATCAACTTCTGCCGCAAGGTGAAGCTGCCCATCATCGGGGTGGTGGAGAAC
ATGAGTGGCTTCATCTGTCCTAAGTGCAAGAAAGAATCTCAGATATTCCCTCCCACAACCGGGG
GCGCGGAGCTCATGTGCCAGGACTTGGAGGTCCCTCTCCTCGGCAGAGTGCCCCTGGATCCGCT
CATAGGAATCCAAGAGTTTTGTAATCTCCATCAGTCAAAAGAAGAGAACCTCATCAGTTCCTGA
AACGAGAGAATGTTCAGGACCAAGCAGTTACCGAGCGAGGCACTCACTGGGCAGCACATCCAGC
CAGACCCGACCAGCTCCGGGATGGGGTGGGTCACAGCAAAAGGACCAGATGCTGGTGTGGTCCG
AAGCCACTTTCTCAGAGACACTTTAATCATTGAGTATTTGTACACTTTTCTTTAGAACATATAT
AAAGGGCATTCTCTACAAATGTGCCGTTTTAAGAATAAAACCCCCTCAAATCTC

hide sequence

RefSeq Acc Id:

NM_001323595 ⟹ NP_001310524

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	16	10,743,842 - 10,769,351 (+)	NCBI
CHM1_1	16	10,837,786 - 10,863,204 (+)	NCBI
T2T-CHM13v2.0	16	10,779,762 - 10,805,269 (+)	NCBI

Sequence:

show sequence

CGAAGGCGGCAAAGGCGACGGAATGGAGGAGGTGCCTCACGACTGTCCAGGGGCCGACAGCGCC
CAGGCGGGCAGAGGGGCTTCATGTCAGGGATGCCCCAACCAGCGGCTGTGCGCTTCTGGAGCGG
GGGCCACTCCGGACACGGCTATAGAGGAAATCAAAGAGAAAATGAAGACTGTAAAACACAAAAT
CTTGGTATTGTCTGGGAAAGGCGGTGTTGGGAAAAGCACATTCAGCGCCCACCTTGCCCATGGC
CTAGCAGAGGATGAAAACACACAGATTGCTCTTCTAGACATCGATATATGTGGGCCATCGATTC
CCAAGATAATGGGATTGGAAGGAGAGCAGGTTCACCAGAGTGGCTCAGGCTGGTCTCCAGTGTA
CGTGGAAGACAACCTGGGGGTGATGTCAGTGGGCTTCCTGCTCAGCAGTCCTGATGATGCTGTT
ATCTGGAGGGGACCCAAGAAAAACGGCATGATCAAGCAGTTCCTCCGAGATGTGGACTGGGGAG
AGGTCGACTACCTCATTGTGGACACCCCACCTGGGACGTCGGATGAACACCTCTCGGTCGTCCG
GTACCTGGCCACAGCACACATCGATGGAGCAGTGATCATCACCACTCCCCAGGAGGTGTCACTC
CAGGATGTCCGGAAAGAAATCAACTTCTGCCGCAAGGTGAAGCTGCCCATCATCGGGGTGGTGG
AGAACATGAGTGGCTTCATCTGTCCTAAGTGCAAGAAAGAATCTCAGATATTCCCTCCCACAAC
CGGGGGCGCGGAGCTCATGTGCCAGGACTTGGAGGTCCCTCTCCTCGGCAGAGTGCCCCTGGAT
CCGCTCATAGGAATCCAAGAGTTTTGTAATCTCCATCAGTCAAAAGAAGAGAACCTCATCAGTT
CCTGAAACGAGAGAATGTTCAGGACCAAGCAGTTACCGAGCGAGGCACTCACTGGGCAGCACAT
CCAGCCAGACCCGACCAGCTCCGGGATGGGGTGGGTCACAGCAAAAGGACCAGATGCTGGTGTG
GTCCGAAGCCACTTTCTCAGAGACACTTTAATCATTGAGTATTTGTACACTTTTCTTTAGAACA
TATATAAAGGGCATTCTCTACAAATGTGCCGTTTTAAGAATAAAACCCCCTCAAATCTC

hide sequence

RefSeq Acc Id:

NM_001323596 ⟹ NP_001310525

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	16	10,743,842 - 10,769,351 (+)	NCBI
CHM1_1	16	10,837,761 - 10,863,204 (+)	NCBI
T2T-CHM13v2.0	16	10,779,762 - 10,805,269 (+)	NCBI

Sequence:

show sequence

CGAAGGCGGCAAAGGCGACGGAATGGAGGAGGTGCCTCACGACTGTCCAGGGGCCGACAGCGCC
CAGGCGGGCAGAGGGGCTTCATGTCAGGGATGCCCCAACCAGCGGCTGTGCGCTTCTGGAGCGG
GGGCCACTCCGGACACGGCTATAGAGGAAATCAAAGAGAAAATGAAGACTGTAAAACACAAAAT
CTTGGTATTGTCTGGGAAAGGCGGTGTTGGGAAAAGCACATTCAGCGCCCACCTTGCCCATGGC
CTAGCAGAGGATGAAAACACACAGATTGCTCTTCTAGACATCGATATATGTGGGCCATCGATTC
CCAAGATAATGGGATTGGAAGGAGAGCAGGTTCACCAGAGTGGCTCAGGCTGGTCTCCAGTGTA
CGTGGAAGACAACCTGGGGGTGATGTCAGTGGGCTTCCTGCTCAGCAGTCCTGATGATGCTGTT
ATCTGGAGGGGACCCAAGAAAAACGGCATGATCAAGCAGTTCCTCCGAGATGTGGACTGGGGAG
AGGTCGACTACCTCATTGTGGACACCCCACCTGGGACGTCGGATGAACACCTCTCGGTCGTCCG
GTACCTGGCCACAGCACACATCGATGGAGCAGTGATCATCACCACTCCCCAGGAGGTGTCACTC
CAGGATGTCCGGAAAGAAATCAACTTCTGCCGCAAGGTGAAGCTGCCCATCATCGGGGTGGTGG
AGAACATGAGTGGCTTCATCTGTCCTAAGTGCAAGGTAAGAATTGTGACAAAGGCCAGTCTTTT
TTCATTGACGCCCCAGATTCCCCAGCCACGTTAGCCTACAGAAGTATAATTCAGAGAATCCAAG
AGTTTTGTAATCTCCATCAGTCAAAAGAAGAGAACCTCATCAGTTCCTGAAACGAGAGAATGTT
CAGGACCAAGCAGTTACCGAGCGAGGCACTCACTGGGCAGCACATCCAGCCAGACCCGACCAGC
TCCGGGATGGGGTGGGTCACAGCAAAAGGACCAGATGCTGGTGTGGTCCGAAGCCACTTTCTCA
GAGACACTTTAATCATTGAGTATTTGTACACTTTTCTTTAGAACATATATAAAGGGCATTCTCT
ACAAATGTGCCGTTTTAAGAATAAAACCCCCTCAAATCTC

hide sequence

RefSeq Acc Id:

NM_001323597 ⟹ NP_001310526

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	16	10,743,869 - 10,769,349 (+)	NCBI
CHM1_1	16	10,837,795 - 10,863,202 (+)	NCBI
T2T-CHM13v2.0	16	10,779,789 - 10,805,267 (+)	NCBI

Sequence:

show sequence

GGAGGTGCCTCACGACTGTCCAGGGGCCGACAGCGCCCAGGCGGGCAGAGGGGCTTCATGTCAG
GGATGCCCCAACCAGCGGCTGTGCGCTTCTGGAGCGGGGGCCACTCCGGACACGGCTATAGAGG
AAATCAAAGAGAAAATGAAGACTGTAAAACACAAAATCTTGGTATTGTCTGGGAAAGGCGGTGT
TGGGAAAAGCACATTCAGCGCCCACCTTGCCCATGGCCTAGCAGAGGATGAAAACACACAGATT
GCTCTTCTAGACATCGATATATGTGGGCCATCGATTCCCAAGATAATGGGATTGGAAGGAGAGC
AGGTTCACCAGAGTGGCTCAGGCTGGTCTCCAGTGTACGTGGAAGACAACCTGGGGGTGATGTC
AGTGGGCTTCCTGCTCAGCAGTCCTGATGATGCTGTTATCTGGAGGGGACCCAAGAAAAACGGC
ATGATCAAGCAGTTCCTCCGAGATGTGGACTGGGGAGAGGTCGACTACCTCATTGTGGACACCC
CACCTGGGACGTCGGATGAACACCTCTCGGTCGTCCGGTACCTGGCCACAGCACACATCGATGG
AGCAGTGATCATCACCACTCCCCAGGAGGTGTCACTCCAGGATGTCCGGAAAGAAATCAACTTC
TGCCGCAAGGTGAAGCTGCCCATCATCGGGGTGGTGGAGAACATGAGTGGCTTCATCTGTCCTA
AGTGCAAGAAAGAATCTCAGATATTCCCTCCCACAACCGGGGGCGCGGAGCTCATGTGCCAGGA
CTTGGAGGTCCCTCTCCTCGGCAGAGTGCCCCTGGATCCGCTCATAGGTGGAATTGTGACAAAG
GCCAGTCTTTTTTCATTGACGCCCCAGATTCCCCAGCCACGTTAGCCTACAGAAGTATAATTCA
GAGAATCCAAGAGTTTTGTAATCTCCATCAGTCAAAAGAAGAGAACCTCATCAGTTCCTGAAAC
GAGAGAATGTTCAGGACCAAGCAGTTACCGAGCGAGGCACTCACTGGGCAGCACATCCAGCCAG
ACCCGACCAGCTCCGGGATGGGGTGGGTCACAGCAAAAGGACCAGATGCTGGTGTGGTCCGAAG
CCACTTTCTCAGAGACACTTTAATCATTGAGTATTTGTACACTTTTCTTTAGAACATATATAAA
GGGCATTCTCTACAAATGTGCCGTTTTAAGAATAAAACCCCCTCAAATC

hide sequence

RefSeq Acc Id:

NM_002484 ⟹ NP_002475

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	16	10,743,842 - 10,769,351 (+)	NCBI
GRCh37	16	10,837,643 - 10,863,208 (+)	NCBI
Build 36	16	10,745,199 - 10,770,709 (+)	NCBI Archive
Celera	16	11,007,059 - 11,032,475 (+)	RGD
HuRef	16	10,756,412 - 10,781,588 (+)	NCBI
CHM1_1	16	10,837,712 - 10,863,204 (+)	NCBI
T2T-CHM13v2.0	16	10,779,762 - 10,805,269 (+)	NCBI

Sequence:

show sequence

CGAAGGCGGCAAAGGCGACGGAATGGAGGAGGTGCCTCACGACTGTCCAGGGGCCGACAGCGCC
CAGGCGGGCAGAGGGGCTTCATGTCAGGGATGCCCCAACCAGCGGCTGTGCGCTTCTGGAGCGG
GGGCCACTCCGGACACGGCTATAGAGGAAATCAAAGAGAAAATGAAGACTGTAAAACACAAAAT
CTTGGTATTGTCTGGGAAAGGCGGTGTTGGGAAAAGCACATTCAGCGCCCACCTTGCCCATGGC
CTAGCAGAGGATGAAAACACACAGATTGCTCTTCTAGACATCGATATATGTGGGCCATCGATTC
CCAAGATAATGGGATTGGAAGGAGAGCAGGTTCACCAGAGTGGCTCAGGCTGGTCTCCAGTGTA
CGTGGAAGACAACCTGGGGGTGATGTCAGTGGGCTTCCTGCTCAGCAGTCCTGATGATGCTGTT
ATCTGGAGGGGACCCAAGAAAAACGGCATGATCAAGCAGTTCCTCCGAGATGTGGACTGGGGAG
AGGTCGACTACCTCATTGTGGACACCCCACCTGGGACGTCGGATGAACACCTCTCGGTCGTCCG
GTACCTGGCCACAGCACACATCGATGGAGCAGTGATCATCACCACTCCCCAGGAGGTGTCACTC
CAGGATGTCCGGAAAGAAATCAACTTCTGCCGCAAGGTGAAGCTGCCCATCATCGGGGTGGTGG
AGAACATGAGTGGCTTCATCTGTCCTAAGTGCAAGAAAGAATCTCAGATATTCCCTCCCACAAC
CGGGGGCGCGGAGCTCATGTGCCAGGACTTGGAGGTCCCTCTCCTCGGCAGAGTGCCCCTGGAT
CCGCTCATAGGTAAGAATTGTGACAAAGGCCAGTCTTTTTTCATTGACGCCCCAGATTCCCCAG
CCACGTTAGCCTACAGAAGTATAATTCAGAGAATCCAAGAGTTTTGTAATCTCCATCAGTCAAA
AGAAGAGAACCTCATCAGTTCCTGAAACGAGAGAATGTTCAGGACCAAGCAGTTACCGAGCGAG
GCACTCACTGGGCAGCACATCCAGCCAGACCCGACCAGCTCCGGGATGGGGTGGGTCACAGCAA
AAGGACCAGATGCTGGTGTGGTCCGAAGCCACTTTCTCAGAGACACTTTAATCATTGAGTATTT
GTACACTTTTCTTTAGAACATATATAAAGGGCATTCTCTACAAATGTGCCGTTTTAAGAATAAA
ACCCCCTCAAATCTC

hide sequence

RefSeq Acc Id:

XM_047434170 ⟹ XP_047290126

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	16	10,743,842 - 10,769,351 (+)	NCBI

RefSeq Acc Id:

XM_054380401 ⟹ XP_054236376

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
T2T-CHM13v2.0	16	10,779,762 - 10,805,269 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001265435	(Get FASTA)	NCBI Sequence Viewer
	NP_001310523	(Get FASTA)	NCBI Sequence Viewer
	NP_001310524	(Get FASTA)	NCBI Sequence Viewer
	NP_001310525	(Get FASTA)	NCBI Sequence Viewer
	NP_001310526	(Get FASTA)	NCBI Sequence Viewer
	NP_002475	(Get FASTA)	NCBI Sequence Viewer
	XP_047290126	(Get FASTA)	NCBI Sequence Viewer
	XP_054236376	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAA61932	(Get FASTA)	NCBI Sequence Viewer
	AAI00291	(Get FASTA)	NCBI Sequence Viewer
	AAI09323	(Get FASTA)	NCBI Sequence Viewer
	AAI09324	(Get FASTA)	NCBI Sequence Viewer
	BAD96924	(Get FASTA)	NCBI Sequence Viewer
	EAW85178	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSP00000283027
	ENSP00000283027.5
	ENSP00000409654
	ENSP00000409654.2
	ENSP00000460288.1
	ENSP00000461723.1
	ENSP00000461746.1
GenBank Protein	P53384	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_002475 ⟸ NM_002484
- Peptide Label:	isoform 1
- UniProtKB:	Q498A9 (UniProtKB/Swiss-Prot), Q32M30 (UniProtKB/Swiss-Prot), Q53FS7 (UniProtKB/Swiss-Prot), P53384 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MEEVPHDCPGADSAQAGRGASCQGCPNQRLCASGAGATPDTAIEEIKEKMKTVKHKILVLSGKG GVGKSTFSAHLAHGLAEDENTQIALLDIDICGPSIPKIMGLEGEQVHQSGSGWSPVYVEDNLGV MSVGFLLSSPDDAVIWRGPKKNGMIKQFLRDVDWGEVDYLIVDTPPGTSDEHLSVVRYLATAHI DGAVIITTPQEVSLQDVRKEINFCRKVKLPIIGVVENMSGFICPKCKKESQIFPPTTGGAELMC QDLEVPLLGRVPLDPLIGKNCDKGQSFFIDAPDSPATLAYRSIIQRIQEFCNLHQSKEENLISS hide sequence

RefSeq Acc Id:	NP_001265435 ⟸ NM_001278506
- Peptide Label:	isoform 2
- UniProtKB:	P53384 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MEEVPHDCPGADSAQAGRGASCQGCPNQRLCASGAGATPDTAIEEIKEKMKTVKHKILVLSGKG GVGKSTFSAHLAHGLAEDENTQIALLDIDICGPSIPKIMGLEGEQYVEDNLGVMSVGFLLSSPD DAVIWRGPKKNGMIKQFLRDVDWGEVDYLIVDTPPGTSDEHLSVVRYLATAHIDGAVIITTPQE VSLQDVRKEINFCRKVKLPIIGVVENMSGFICPKCKKESQIFPPTTGGAELMCQDLEVPLLGRV PLDPLIGKNCDKGQSFFIDAPDSPATLAYRSIIQRIQEFCNLHQSKEENLISS hide sequence

RefSeq Acc Id:

NP_001310525 ⟸ NM_001323596

- Peptide Label:

isoform 5

- Sequence:

show sequence

MEEVPHDCPGADSAQAGRGASCQGCPNQRLCASGAGATPDTAIEEIKEKMKTVKHKILVLSGKG
GVGKSTFSAHLAHGLAEDENTQIALLDIDICGPSIPKIMGLEGEQVHQSGSGWSPVYVEDNLGV
MSVGFLLSSPDDAVIWRGPKKNGMIKQFLRDVDWGEVDYLIVDTPPGTSDEHLSVVRYLATAHI
DGAVIITTPQEVSLQDVRKEINFCRKVKLPIIGVVENMSGFICPKCKVRIVTKASLFSLTPQIP
QPR

hide sequence

RefSeq Acc Id:

NP_001310523 ⟸ NM_001323594

- Peptide Label:

isoform 3

- Sequence:

show sequence

MEEVPHDCPGADSAQAGRGASCQGCPNQRLCASGAGATPDTAIEEIKEKMKTVKHKILVLSGKG
GVGKSTFSAHLAHGLAEDENTQVHQSGSGWSPVYVEDNLGVMSVGFLLSSPDDAVIWRGPKKNG
MIKQFLRDVDWGEVDYLIVDTPPGTSDEHLSVVRYLATAHIDGAVIITTPQEVSLQDVRKEINF
CRKVKLPIIGVVENMSGFICPKCKKESQIFPPTTGGAELMCQDLEVPLLGRVPLDPLIGIQEFC
NLHQSKEENLISS

hide sequence

RefSeq Acc Id:

NP_001310524 ⟸ NM_001323595

- Peptide Label:

isoform 4

- Sequence:

show sequence

MEEVPHDCPGADSAQAGRGASCQGCPNQRLCASGAGATPDTAIEEIKEKMKTVKHKILVLSGKG
GVGKSTFSAHLAHGLAEDENTQIALLDIDICGPSIPKIMGLEGEQVHQSGSGWSPVYVEDNLGV
MSVGFLLSSPDDAVIWRGPKKNGMIKQFLRDVDWGEVDYLIVDTPPGTSDEHLSVVRYLATAHI
DGAVIITTPQEVSLQDVRKEINFCRKVKLPIIGVVENMSGFICPKCKKESQIFPPTTGGAELMC
QDLEVPLLGRVPLDPLIGIQEFCNLHQSKEENLISS

hide sequence

RefSeq Acc Id:

NP_001310526 ⟸ NM_001323597

- Peptide Label:

isoform 6

- Sequence:

show sequence

MKTVKHKILVLSGKGGVGKSTFSAHLAHGLAEDENTQIALLDIDICGPSIPKIMGLEGEQVHQS
GSGWSPVYVEDNLGVMSVGFLLSSPDDAVIWRGPKKNGMIKQFLRDVDWGEVDYLIVDTPPGTS
DEHLSVVRYLATAHIDGAVIITTPQEVSLQDVRKEINFCRKVKLPIIGVVENMSGFICPKCKKE
SQIFPPTTGGAELMCQDLEVPLLGRVPLDPLIGGIVTKASLFSLTPQIPQPR

hide sequence

Ensembl Acc Id:

ENSP00000460288 ⟸ ENST00000571175

Ensembl Acc Id:

ENSP00000283027 ⟸ ENST00000283027

Ensembl Acc Id:

ENSP00000461746 ⟸ ENST00000574334

Ensembl Acc Id:

ENSP00000461723 ⟸ ENST00000574691

Ensembl Acc Id:

ENSP00000409654 ⟸ ENST00000433392

RefSeq Acc Id:	XP_047290126 ⟸ XM_047434170
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_054236376 ⟸ XM_054380401
- Peptide Label:	isoform X1

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P53384-F1-model_v2	AlphaFold	P53384	1-320	view protein structure

Promoters

RGD ID:

7231313

Promoter ID:

EPDNEW_H21402

Type:

initiation region

Name:

NUBP1_1

Description:

nucleotide binding protein 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	16	10,743,842 - 10,743,902	EPDNEW

RGD ID:

6793343

Promoter ID:

HG_KWN:23015

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

CD4+TCell, CD4+TCell_12Hour, HeLa_S3, Jurkat, K562, Lymphoblastoid, NB4

Transcripts:

OTTHUMT00000251964, UC002DAB.1, UC010BUM.1

Position:

Human Assembly	Chr	Position (strand)	Source
Build 36	16	10,744,999 - 10,745,499 (+)	MPROMDB

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	HGNC:8041	AgrOrtholog
COSMIC	NUBP1	COSMIC
Ensembl Genes	ENSG00000103274	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript	ENST00000283027	ENTREZGENE
	ENST00000283027.10	UniProtKB/Swiss-Prot
	ENST00000433392	ENTREZGENE
	ENST00000433392.6	UniProtKB/Swiss-Prot
	ENST00000571175.5	UniProtKB/TrEMBL
	ENST00000574334.5	UniProtKB/TrEMBL
	ENST00000574691.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.300	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx	ENSG00000103274	GTEx
HGNC ID	HGNC:8041	ENTREZGENE
Human Proteome Map	NUBP1	Human Proteome Map
InterPro	AAA+_ATPase	UniProtKB/Swiss-Prot
	Mrp/NBP35_ATP-bd	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Mrp_CS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	NUBP1/Nbp35	UniProtKB/Swiss-Prot
	NUBP2/Cfd1_eukaryotes	UniProtKB/TrEMBL
	P-loop_NTPase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	YlxH/NBP35	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	hsa:4682	UniProtKB/Swiss-Prot
NCBI Gene	4682	ENTREZGENE
OMIM	600280	OMIM
PANTHER	CYTOSOLIC FE-S CLUSTER ASSEMBLY FACTOR NUBP1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	CYTOSOLIC FE-S CLUSTER ASSEMBLY FACTOR NUBP2	UniProtKB/TrEMBL
	PTHR23264	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	ParA	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB	PA31823	PharmGKB
PROSITE	MRP	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	AAA	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF52540	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	I3L3A0_HUMAN	UniProtKB/TrEMBL
	I3L518_HUMAN	UniProtKB/TrEMBL
	I3L531_HUMAN	UniProtKB/TrEMBL
	NUBP1_HUMAN	UniProtKB/Swiss-Prot, ENTREZGENE
	Q2YS46_HUMAN	UniProtKB/TrEMBL
	Q32M30	ENTREZGENE
	Q498A9	ENTREZGENE
	Q53FS7	ENTREZGENE
UniProt Secondary	Q32M30	UniProtKB/Swiss-Prot
	Q498A9	UniProtKB/Swiss-Prot
	Q53FS7	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-12-20	NUBP1	NUBP iron-sulfur cluster assembly factor 1, cytosolic	NUBP1	nucleotide binding protein 1	Symbol and/or name change	19259463	PROVISIONAL
2011-07-27	NUBP1	nucleotide binding protein 1	NUBP1	nucleotide binding protein 1 (MinD homolog, E. coli)	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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