Ube2ql1 (ubiquitin-conjugating enzyme E2Q family-like 1) - Rat Genome Database

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Gene: Ube2ql1 (ubiquitin-conjugating enzyme E2Q family-like 1) Mus musculus
Analyze
Symbol: Ube2ql1
Name: ubiquitin-conjugating enzyme E2Q family-like 1
RGD ID: 1321324
MGI Page MGI
Description: Predicted to have ubiquitin conjugating enzyme activity. Predicted to be involved in protein polyubiquitination. Predicted to localize to nucleoplasm and plasma membrane. Is expressed in central nervous system and dorsal root ganglion. Orthologous to human UBE2QL1 (ubiquitin conjugating enzyme E2 Q family like 1); PARTICIPATES IN ubiquitin/proteasome degradation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 3110006E14Rik; E2Q-like ubiquitin-conjugating enzyme 1; probable ubiquitin-conjugating enzyme E2 FLJ25076 homolog; ubiquitin-conjugating enzyme E2Q-like protein 1
RGD Orthologs
Human
Rat
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391369,850,951 - 69,888,016 (-)NCBIGRCm39mm39
GRCm39 Ensembl1369,850,951 - 69,888,008 (-)Ensembl
GRCm381369,702,832 - 69,739,897 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1369,702,832 - 69,739,889 (-)EnsemblGRCm38mm10GRCm38
MGSCv371369,841,710 - 69,878,775 (-)NCBIGRCm37mm9NCBIm37
MGSCv361370,170,200 - 70,206,712 (-)NCBImm8
Celera1372,047,268 - 72,084,442 (-)NCBICelera
Cytogenetic Map13B3- C1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleoplasm  (ISO)
nucleus  (IBA,ISO)
plasma membrane  (ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:12477932   PMID:15489334   PMID:16141072   PMID:16141073   PMID:21267068   PMID:21873635   PMID:23431145   PMID:31202927  


Genomics

Comparative Map Data
Ube2ql1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391369,850,951 - 69,888,016 (-)NCBIGRCm39mm39
GRCm39 Ensembl1369,850,951 - 69,888,008 (-)Ensembl
GRCm381369,702,832 - 69,739,897 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1369,702,832 - 69,739,889 (-)EnsemblGRCm38mm10GRCm38
MGSCv371369,841,710 - 69,878,775 (-)NCBIGRCm37mm9NCBIm37
MGSCv361370,170,200 - 70,206,712 (-)NCBImm8
Celera1372,047,268 - 72,084,442 (-)NCBICelera
Cytogenetic Map13B3- C1NCBI
UBE2QL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl56,448,859 - 6,496,723 (+)EnsemblGRCh38hg38GRCh38
GRCh3856,437,347 - 6,496,723 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3756,448,972 - 6,496,836 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3656,490,460 - 6,548,029 (+)NCBINCBI36hg18NCBI36
Celera56,476,425 - 6,520,375 (+)NCBI
Cytogenetic Map5p15.31NCBI
HuRef56,466,054 - 6,471,560 (+)NCBIHuRef
CHM1_156,448,829 - 6,496,771 (+)NCBICHM1_1
Ube2ql1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2133,548,814 - 33,589,174 (+)NCBI
Rnor_6.0 Ensembl136,185,916 - 36,226,276 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0136,185,916 - 36,226,276 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0137,582,312 - 37,622,672 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4173,700,392 - 3,740,804 (+)NCBIRGSC3.4rn4RGSC3.4
Celera132,158,184 - 32,198,529 (+)NCBICelera
Cytogenetic Map1p11NCBI
UBE2QL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Mhudiblu_PPA_v056,772,764 - 6,817,062 (+)NCBIMhudiblu_PPA_v0panPan3
UBE2QL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1347,237,350 - 7,277,847 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl347,238,561 - 7,277,853 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3411,747,421 - 11,788,422 (-)NCBI
ROS_Cfam_1.0347,147,582 - 7,188,609 (-)NCBI
UMICH_Zoey_3.1347,194,330 - 7,235,522 (-)NCBI
UNSW_CanFamBas_1.0347,174,627 - 7,215,642 (-)NCBI
UU_Cfam_GSD_1.0347,387,934 - 7,428,940 (-)NCBI
UBE2QL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1675,428,275 - 75,474,044 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11675,428,272 - 75,474,506 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21681,787,687 - 81,834,321 (-)NCBISscrofa10.2Sscrofa10.2susScr3
UBE2QL1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.146,136,142 - 6,179,292 (+)NCBI
ChlSab1.1 Ensembl46,136,037 - 6,178,048 (+)Ensembl
Ube2ql1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247514,193,968 - 4,228,468 (+)NCBI


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884393Humsd7_mhumerus midshaft diameter 7, 16 week (mouse)13390000075900000Mouse
4142147Mvwf4_mmodifier of von Willebrand factor 4 (mouse)Not determined20293442112761890Mouse
4142009Pregq3_mpregnancy QTL 3 (mouse)Not determined132043134272237070Mouse
10412235Scgq5_mspontaneous crescentic glomerulonephritis QTL 5 (mouse)Not determined133587692596102654Mouse
1301734Acsns2_mAngiostrongylus costaricensis nematode susceptibility 2 (mouse)Not determined133594749469947604Mouse
1357587Pfat3_mpredicted fat percentage 3 (mouse)Not determined133594749469947604Mouse
1300561Heal7_mwound healing/regeneration 7 (mouse)Not determined133599078469990868Mouse
1300862Cfbw5_mcystic fibrosis body weight 5 (mouse)Not determined133857254572572704Mouse
1301801Cpfd5_mcerebellum pattern fissures (mouse)Not determined133948143673481584Mouse
1302157Bwem2_mbody weight day 30 males 2 (mouse)Not determined133948143673481584Mouse
1300985Bmd13_mbone mineral density 13 (mouse)Not determined133948143673481584Mouse
15039353Nmrs35_mNAFLD-associated magnetic resonance shift 35 (mouse)134044044074440440Mouse
1300668Pas10_mpulmonary adenoma susceptibility 10 (mouse)Not determined134134122875341344Mouse
4142331Bxs6_mBXSB/MpJ autoimmune nephritis 6 (mouse)Not determined4505696683596627Mouse
10412109Bxs7_mBXSB/MpJ autoimmune nephritis 7 (mouse)Not determined134505696683596627Mouse
26884396Humsd4_mhumerus midshaft diameter 4, 10 week (mouse)134770000073000000Mouse
4142372Moo2_mmodifier of Odc2 (mouse)Not determinedX5017034784170495Mouse
1300916Mobe2_mmodifier of obesity 2 (mouse)Not determined135017034784170495Mouse
1301666Eae13_msusceptibility to experimental allergic encephalomyelitis 13 (mouse)Not determined135017034784170495Mouse
1300573Elsgp2_melevated serum gp70 2 (mouse)Not determined135046870984468908Mouse
14746975Manh74_mmandible shape 74 (mouse)135232915086329150Mouse
1302073Pgct1_mprimordial germ cell tumor locus 1 (mouse)Not determined135367266487672778Mouse
1357563Bmch6_mbone mechanical trait 6 (mouse)Not determined135523686189237021Mouse
4142241Tailq3_mtail length QTL 3 (mouse)Not determined55572541112294569Mouse
4141992W6q16_mweight 6 weeks QTL 16 (mouse)Not determined55572541112294569Mouse
4142314Tailaq3_mtail length adjusted QTL 3 (mouse)Not determined55572541112294569Mouse
4140959W10q17_mweight 10 weeks QTL 17 (mouse)Not determined55572541112294569Mouse
1558850Sgp3_mserum gp70 production 3 (mouse)Not determined135632264376823195Mouse
10402414Sgp5_mserum gp70 production 5 (mouse)Not determined1356322643105285678Mouse
1357553Cia28_mcollagen induced arthritis 28 (mouse)Not determined135648143696102654Mouse
10412163Wra1_mwheel running activity 1 (mouse)Not determined135898448192984619Mouse
1300941Skl6_mskeletal size (tail length) 6 (mouse)Not determined136410270298102826Mouse
1301949Skull20_mskull morphology 20 (mouse)Not determined136410270298102826Mouse
1301445Listr2_mlisteriosis resistance 2 (mouse)Not determined1366596482100596627Mouse
1301593Heal8_mwound healing/regeneration 8 (mouse)Not determined1367905880101906000Mouse
14696726Kidrq3_mkidney weight, right QTL 3 (mouse)1368068947102068947Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:486
Count of miRNA genes:328
Interacting mature miRNAs:375
Transcripts:ENSMUST00000065118
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000065118   ⟹   ENSMUSP00000070906
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1369,702,832 - 69,739,889 (-)Ensembl
RefSeq Acc Id: NM_001145162   ⟹   NP_001138634
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391369,850,951 - 69,888,016 (-)NCBI
GRCm381369,702,832 - 69,739,897 (-)ENTREZGENE
MGSCv371369,841,710 - 69,878,775 (-)RGD
Celera1372,047,268 - 72,084,442 (-)RGD
cM Map13 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_001138634 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein A0PJN4 (Get FASTA)   NCBI Sequence Viewer  
  AAH58543 (Get FASTA)   NCBI Sequence Viewer  
  AAI16980 (Get FASTA)   NCBI Sequence Viewer  
  AAI16982 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001138634   ⟸   NM_001145162
- UniProtKB: A0PJN4 (UniProtKB/Swiss-Prot),   E9QMD2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000070906   ⟸   ENSMUST00000065118
Protein Domains
UBC core

Promoters
RGD ID:8680770
Promoter ID:EPDNEW_M18416
Type:initiation region
Name:Ube2ql1_1
Description:Mus musculus ubiquitin-conjugating enzyme E2Q family-like 1 ,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381369,739,881 - 69,739,941EPDNEW
RGD ID:6824462
Promoter ID:MM_KWN:14621
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:NM_001145162
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361369,877,566 - 69,878,667 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1924230 AgrOrtholog
Ensembl Genes ENSMUSG00000052981 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000070906 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000065118 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 3.10.110.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro UBQ-conjugat_E2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UBQ-conjugating_enzyme/RWD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:76980 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1924230 ENTREZGENE
NCBI Gene 76980 ENTREZGENE
Pfam UQ_con UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ube2ql1 PhenoGen
PROSITE UBIQUITIN_CONJUGAT_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF54495 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0PJN4 ENTREZGENE
  E9QMD2 ENTREZGENE, UniProtKB/TrEMBL
  U2QL1_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q6PDR7 UniProtKB/Swiss-Prot