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Gene: PIK3C2A (phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha) Homo sapiens
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Symbol: PIK3C2A
Name: phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha
Description: Predicted to have 1-phosphatidylinositol-3-kinase activity and 1-phosphatidylinositol-4-phosphate 3-kinase activity. Involved in endocytosis; positive regulation of autophagy; and positive regulation of cell migration involved in sprouting angiogenesis. Localizes to several cellular components, including nucleoplasm; plasma membrane; and vesicle. Biomarker of type 2 diabetes mellitus.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C2-containing phosphatidylinositol kinase; CPK; DKFZp686L193; MGC142218; OCSKD; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha; phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit alpha; phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha; phosphoinositide 3-kinase-C2-alpha; phosphoinositide-3-kinase, class 2, alpha polypeptide; PI3-K-C2(ALPHA); PI3-K-C2A; PI3K-C2-alpha; PI3K-C2alpha; ptdIns-3-kinase C2 subunit alpha
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1117,077,730 - 17,207,983 (-)EnsemblGRCh38hg38GRCh38
GRCh381117,086,575 - 17,207,986 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371117,108,108 - 17,229,543 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361117,064,698 - 17,147,930 (-)NCBINCBI36hg18NCBI36
Build 341117,067,860 - 17,147,864NCBI
Celera1117,236,314 - 17,320,701 (-)NCBI
Cytogenetic Map11p15.1NCBI
HuRef1116,791,536 - 16,875,065 (-)NCBIHuRef
CHM1_11117,107,728 - 17,229,116 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on PIK3C2A
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1321266
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.