Cyfip1 (cytoplasmic FMR1 interacting protein 1) - Rat Genome Database

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Gene: Cyfip1 (cytoplasmic FMR1 interacting protein 1) Mus musculus
Analyze
Symbol: Cyfip1
Name: cytoplasmic FMR1 interacting protein 1
RGD ID: 1321176
MGI Page MGI
Description: Enables translation regulator activity. Involved in several processes, including dendrite extension; positive regulation of neurotrophin TRK receptor signaling pathway; and regulation of modification of postsynaptic actin cytoskeleton. Acts upstream of or within lamellipodium assembly. Located in lamellipodium; neuron projection; and perinuclear region of cytoplasm. Part of mRNA cap binding activity complex. Is active in postsynapse. Is expressed in several structures, including embryo mesenchyme; lung; nervous system; skeletal muscle; and tooth. Human ortholog(s) of this gene implicated in autism spectrum disorder and schizophrenia. Orthologous to human CYFIP1 (cytoplasmic FMR1 interacting protein 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: cytoplasmic FMR1-interacting protein 1; E030028J09Rik; KIAA0068; l(7); l(7)1Rl; l7; l71Rl; l7Rl1; mKIAA0068; P140S; P140SRA-1; P140sra1; pl; pl-1; Shy; Shyc; specifically Rac1-associated protein 1; Sr; Sra-1; Sra1
RGD Orthologs
Human
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39755,491,556 - 55,582,381 (+)NCBIGRCm39mm39
GRCm39 Ensembl755,491,493 - 55,582,350 (+)Ensembl
GRCm38755,842,022 - 55,932,633 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl755,841,745 - 55,932,602 (+)EnsemblGRCm38mm10GRCm38
MGSCv37763,097,441 - 63,188,003 (+)NCBIGRCm37mm9NCBIm37
MGSCv36755,739,875 - 55,798,505 (+)NCBImm8
Celera753,195,732 - 53,286,248 (+)NCBICelera
Cytogenetic Map7B5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Haploinsufficiency of Cyfip1 produces fragile X-like phenotypes in mice. Bozdagi O, etal., PLoS One. 2012;7(8):e42422. doi: 10.1371/journal.pone.0042422. Epub 2012 Aug 10.
2. Up-regulated cytoplasmic FMRP-interacting protein 1 in intractable temporal lobe epilepsy patients and a rat model. Huang Y Int J Neurosci. 2015 Aug 24:1-10.
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. The Prader-Willi phenotype of fragile X syndrome. Nowicki ST, etal., J Dev Behav Pediatr. 2007 Apr;28(2):133-8.
5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6. Mouse MP Annotation Import Pipeline RGD automated import pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Rho GTPases in insulin-stimulated glucose uptake. Satoh T Small GTPases. 2014;5:e28102. doi: 10.4161/sgtp.28102. Epub 2014 Mar 10.
10. Confirmed rare copy number variants implicate novel genes in schizophrenia. Tam GW, etal., Biochem Soc Trans. 2010 Apr;38(2):445-51. doi: 10.1042/BST0380445.
11. A co-segregating microduplication of chromosome 15q11.2 pinpoints two risk genes for autism spectrum disorder. van der Zwaag B, etal., Am J Med Genet B Neuropsychiatr Genet. 2010 Jun 5;153B(4):960-6. doi: 10.1002/ajmg.b.31055.
12. Common variants in genes of the postsynaptic FMRP signalling pathway are risk factors for autism spectrum disorders. Waltes R, etal., Hum Genet. 2014 Jun;133(6):781-92. doi: 10.1007/s00439-013-1416-y. Epub 2014 Jan 19.
Additional References at PubMed
PMID:8601493   PMID:8889548   PMID:9463375   PMID:9756361   PMID:10349636   PMID:10725249   PMID:10903848   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11438699  
PMID:12477932   PMID:12520002   PMID:12904583   PMID:14508708   PMID:14610273   PMID:14765121   PMID:15489334   PMID:15782199   PMID:16141072   PMID:16141073   PMID:16512683   PMID:17967808  
PMID:18799693   PMID:18805096   PMID:21267068   PMID:21677750   PMID:21873635   PMID:21946561   PMID:24050404   PMID:24357318   PMID:24439377   PMID:24457600   PMID:24667445   PMID:25311365  
PMID:25588502   PMID:26365490   PMID:26474913   PMID:26843638   PMID:27507650   PMID:27605705   PMID:27889896   PMID:28183735   PMID:28290521   PMID:28671696   PMID:28706196   PMID:30562941  
PMID:30664619   PMID:30687000   PMID:30784587   PMID:31209152   PMID:31324746   PMID:31371726   PMID:31697813   PMID:31988061   PMID:32325033   PMID:32669345   PMID:33497737   PMID:34031371  


Genomics

Comparative Map Data
Cyfip1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39755,491,556 - 55,582,381 (+)NCBIGRCm39mm39
GRCm39 Ensembl755,491,493 - 55,582,350 (+)Ensembl
GRCm38755,842,022 - 55,932,633 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl755,841,745 - 55,932,602 (+)EnsemblGRCm38mm10GRCm38
MGSCv37763,097,441 - 63,188,003 (+)NCBIGRCm37mm9NCBIm37
MGSCv36755,739,875 - 55,798,505 (+)NCBImm8
Celera753,195,732 - 53,286,248 (+)NCBICelera
Cytogenetic Map7B5NCBI
CYFIP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381522,867,052 - 22,980,898 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1522,867,052 - 22,981,063 (-)EnsemblGRCh38hg38GRCh38
GRCh371522,892,170 - 23,006,016 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361520,444,125 - 20,555,044 (+)NCBINCBI36hg18NCBI36
Build 341520,444,124 - 20,555,043NCBI
Celera151,376,209 - 1,487,232 (-)NCBI
Cytogenetic Map15q11.2NCBI
HuRef151,205,387 - 1,315,987 (+)NCBIHuRef
CHM1_11522,841,725 - 22,952,892 (+)NCBICHM1_1
T2T-CHM13v2.01520,538,904 - 20,652,761 (-)NCBI
Cyfip1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21106,710,924 - 106,799,393 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1106,711,016 - 106,799,386 (+)Ensembl
Rnor_6.01114,258,773 - 114,347,138 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1114,258,719 - 114,347,137 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01115,265,128 - 115,353,515 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41107,245,993 - 107,334,337 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11107,324,324 - 107,412,679 (+)NCBI
Celera1100,921,447 - 101,009,775 (+)NCBICelera
Cytogenetic Map1q22NCBI
CYFIP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11520,462,755 - 20,573,684 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1520,462,811 - 20,573,684 (+)Ensemblpanpan1.1panPan2
CYFIP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1332,096,471 - 32,170,107 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl332,097,037 - 32,187,781 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha334,509,239 - 34,585,945 (+)NCBI
ROS_Cfam_1.0332,162,887 - 32,239,605 (+)NCBI
ROS_Cfam_1.0 Ensembl332,117,281 - 32,240,269 (+)Ensembl
UMICH_Zoey_3.1331,650,943 - 31,773,999 (+)NCBI
UNSW_CanFamBas_1.0331,945,859 - 32,022,546 (+)NCBI
UU_Cfam_GSD_1.0332,056,552 - 32,133,289 (+)NCBI
Cyfip1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640120,416,388 - 120,482,622 (+)NCBI
SpeTri2.0NW_00493647138,264,455 - 38,331,995 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CYFIP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11532,064,431 - 32,175,095 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
CYFIP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12653,562,105 - 53,673,544 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2653,595,767 - 53,672,977 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605436,289,010 - 36,405,036 (+)NCBIVero_WHO_p1.0
Cyfip1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248962,723,462 - 2,800,113 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046248962,726,622 - 2,774,671 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
AV310063  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38755,932,730 - 55,932,870UniSTSGRCm38
MGSCv37763,188,100 - 63,188,240UniSTSGRCm37
Celera753,286,345 - 53,286,485UniSTS
Cytogenetic Map7B5UniSTS
Whitehead/MRC_RH7664.37UniSTS
AF072697  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38755,930,320 - 55,930,408UniSTSGRCm38
MGSCv37763,185,690 - 63,185,778UniSTSGRCm37
Celera753,283,936 - 53,284,024UniSTS
Cytogenetic Map7B5UniSTS
Whitehead/MRC_RH7664.32UniSTS
AU022452  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38755,930,197 - 55,930,437UniSTSGRCm38
MGSCv37763,185,567 - 63,185,807UniSTSGRCm37
Celera753,283,813 - 53,284,053UniSTS
Cytogenetic Map7B5UniSTS
Whitehead/MRC_RH7673.88UniSTS
AV025579  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38755,931,664 - 55,931,778UniSTSGRCm38
MGSCv37763,187,034 - 63,187,148UniSTSGRCm37
Celera753,285,280 - 53,285,394UniSTS
Cytogenetic Map7B5UniSTS
Whitehead/MRC_RH7664.89UniSTS
UniSTS:235677  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38755,931,493 - 55,931,694UniSTSGRCm38
MGSCv37763,186,863 - 63,187,064UniSTSGRCm37
Celera753,285,109 - 53,285,310UniSTS
Cytogenetic Map7B5UniSTS


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300722Sle3_msystemic lupus erythmatosus susceptibility 3 (mouse)Not determined7351172887142720Mouse
38501068Tip1_mtuberculosis immunophenotype 1, spleen CFU (mouse)7360299972549748Mouse
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76502999133501729Mouse
12792978Fbmd3_mfemoral bone mineral density 3, females only (mouse)77050288142367832Mouse
10412199Sst2_msusceptibility to tuberculosis 2 (mouse)Not determined718728794119485380Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719147398141919804Mouse
12904742Litsq2_mlitter size QTL 2 (mouse)72267388756674033Mouse
1301709Bdt4_mbone density traits 4 (mouse)Not determined72288857256888716Mouse
11354952Pdcc1_mplasmacytoid dentritic cell compartment 1 (mouse)72306653157066531Mouse
1301969Lbw5_mlupus NZB x NZW 5 (mouse)Not determined72684761560851775Mouse
12790989Tgl6_mtriglyceride 6 (mouse)72754054961540549Mouse
4141805Sle19_msystematic lupus erythematosus susceptibility 19 (mouse)Not determined3003248581135653Mouse
26884404Huml1_mhumerus length 1, 5 week (mouse)730199425108999207Mouse
1301175Ap7q_malcohol preference 7 QTL (mouse)Not determined73171484565715077Mouse
1300996Aorls2_maortic lesion size 2 (mouse)Not determined73239453266394681Mouse
4142003W3q10_mweight 3 weeks QTL 10 (mouse)Not determined3349772758148965Mouse
4142102Tailq5_mtail length QTL 5 (mouse)Not determined3349772758148965Mouse
4142218W6q17_mweight 6 weeks QTL 17 (mouse)Not determined3349772758148965Mouse
4141909W10q18_mweight 10 weeks QTL 18 (mouse)Not determined3349772758148965Mouse
1357883Epfq5_mepididymal fat pad weight QTL 5 (mouse)Not determined73349772758148965Mouse
1357634Splq7_mspleen weight QTL 7 (mouse)Not determined73349772758148965Mouse
39128210Lwq19_mliver weight QTL 19 (mouse)73349772758148965Mouse
1357469Kidq5_mkidney weight QTL 5 (mouse)Not determined73349772758148965Mouse
1559000Ossc1_mosteosarcoma susceptibility 1 (mouse)Not determined73405302568053223Mouse
10045622Heal20_mwound healing/regeneration 20 (mouse)Not determined73431688768317043Mouse
1357586Mdmsc3_mmodifier of muscularity 3 (mouse)Not determined73444786968448018Mouse
1301514Rigs1_mradiation induced gastroschisis 1 (mouse)Not determined73628001592394346Mouse
1301082Bbaa16_mB.burgdorferi-associated arthritis 16 (mouse)Not determined736280015116416877Mouse
25314301Vmm3_mvariable multisystem mineralization 3, lung (mouse)73729942572049748Mouse
25314303Vmm4_mvariable multisystem mineralization 4, kidney (mouse)73729942587049208Mouse
1300878Skts1_mskin tumor susceptibility 1 (mouse)Not determined73789138671891582Mouse
10402488Dipa2_mdrug induced psychomotor activation 2 (mouse)Not determined73842154872421684Mouse
1300791Abbp3_mA/J and C57BL/6 blood pressure 3 (mouse)Not determined739673887103510010Mouse
11252140Fdr1_mfat response to dietary restriction 1 (mouse)74114882075148965Mouse
4141929Chlq18_mcirculating hormone level QTL 18 (mouse)Not determined74114882075148965Mouse
10043926Bw1n_mbody weight 1 in NSY (mouse)Not determined745161966118693530Mouse
12880417V125Dq5_mvitamin D active form serum level QTL 5 (mouse)74524974879249748Mouse
25314304Vmm1_mvariable multisystem mineralization 1, muzzle (mouse)74714974856549748Mouse
25314302Vmm2_mvariable multisystem mineralization 2, heart (mouse)74714974874149748Mouse
12738423Lfibq6_mliver fibrosis QTL 6 (mouse)74769437866704862Mouse
1302141Fcsa6_mfemoral cross-sectional area 6 (mouse)Not determined74838446182384607Mouse
11532741Tbrs5_mtuberculosis resistance 5 (mouse)74915922783235415Mouse
1357752Tabw_mtally ho asscoiated body weight (mouse)Not determined74919327883193390Mouse
10053685Eae43_mexperimental allergic encephalomyelitis susceptibility 43 (mouse)Not determined75112495485125093Mouse
10054064Bwq11_mbody weight QTL 11 (mouse)Not determined75112495485125093Mouse
13208555Lgth10_mbody length 10 (mouse)751649748125599172Mouse
12880418V125Dq6_mvitamin D active form serum level QTL 6 (mouse)75214974886149748Mouse
27226751Femd5_mfemur midshaft diameter 5, 10 week (mouse)753249748143153737Mouse
25823170Hrsq7_mhost response to SARS QTL 7, log titer (mouse)754819589116822815Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2073
Count of miRNA genes:735
Interacting mature miRNAs:912
Transcripts:ENSMUST00000032629, ENSMUST00000085255, ENSMUST00000163845, ENSMUST00000168271, ENSMUST00000173267, ENSMUST00000173384, ENSMUST00000173497, ENSMUST00000173783, ENSMUST00000174660, ENSMUST00000174793
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001164661 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001164662 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_011370 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006540729 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017322067 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004934046 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC102298 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC144633 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF072697 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ567911 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK028811 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK044175 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK044651 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK052509 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK128952 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK146613 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK152558 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK157773 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK167068 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK170572 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK178624 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK195390 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK196585 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK198587 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK202098 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK203748 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK205520 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK209487 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK209564 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK213711 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK220320 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB228046 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC002174 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC047135 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC052713 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC054429 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC086625 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB527850 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466599 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000032629   ⟹   ENSMUSP00000032629
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl755,491,819 - 55,582,350 (+)Ensembl
GRCm38.p6 Ensembl755,842,071 - 55,932,602 (+)Ensembl
RefSeq Acc Id: ENSMUST00000085255   ⟹   ENSMUSP00000082353
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl755,491,954 - 55,580,246 (+)Ensembl
GRCm38.p6 Ensembl755,842,206 - 55,930,498 (+)Ensembl
RefSeq Acc Id: ENSMUST00000163845   ⟹   ENSMUSP00000127717
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl755,492,003 - 55,580,219 (+)Ensembl
GRCm38.p6 Ensembl755,842,255 - 55,930,471 (+)Ensembl
RefSeq Acc Id: ENSMUST00000168271
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl755,491,493 - 55,542,179 (+)Ensembl
GRCm38.p6 Ensembl755,841,745 - 55,892,431 (+)Ensembl
RefSeq Acc Id: ENSMUST00000173267
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl755,546,822 - 55,580,246 (+)Ensembl
GRCm38.p6 Ensembl755,897,074 - 55,930,498 (+)Ensembl
RefSeq Acc Id: ENSMUST00000173384
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl755,547,567 - 55,554,003 (+)Ensembl
GRCm38.p6 Ensembl755,897,819 - 55,904,255 (+)Ensembl
RefSeq Acc Id: ENSMUST00000173497
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl755,491,998 - 55,575,534 (+)Ensembl
GRCm38.p6 Ensembl755,842,250 - 55,925,786 (+)Ensembl
RefSeq Acc Id: ENSMUST00000173783   ⟹   ENSMUSP00000134509
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl755,491,820 - 55,527,751 (+)Ensembl
GRCm38.p6 Ensembl755,842,072 - 55,878,003 (+)Ensembl
RefSeq Acc Id: ENSMUST00000174660
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl755,546,493 - 55,550,588 (+)Ensembl
GRCm38.p6 Ensembl755,896,745 - 55,900,840 (+)Ensembl
RefSeq Acc Id: ENSMUST00000174793
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl755,558,120 - 55,563,460 (+)Ensembl
GRCm38.p6 Ensembl755,908,372 - 55,913,712 (+)Ensembl
RefSeq Acc Id: ENSMUST00000205656
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl755,578,632 - 55,580,219 (+)Ensembl
GRCm38.p6 Ensembl755,928,884 - 55,930,471 (+)Ensembl
RefSeq Acc Id: ENSMUST00000206862   ⟹   ENSMUSP00000146194
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl755,521,607 - 55,573,708 (+)Ensembl
GRCm38.p6 Ensembl755,871,859 - 55,923,960 (+)Ensembl
RefSeq Acc Id: NM_001164661   ⟹   NP_001158133
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39755,491,819 - 55,582,381 (+)NCBI
GRCm38755,842,071 - 55,932,633 (+)NCBI
MGSCv37763,097,441 - 63,188,003 (+)RGD
Celera753,195,732 - 53,286,248 (+)RGD
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001164662   ⟹   NP_001158134
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39755,491,819 - 55,582,381 (+)NCBI
GRCm38755,842,071 - 55,932,633 (+)NCBI
MGSCv37763,097,441 - 63,188,003 (+)RGD
Celera753,195,732 - 53,286,248 (+)RGD
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_011370   ⟹   NP_035500
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39755,491,819 - 55,582,381 (+)NCBI
GRCm38755,842,071 - 55,932,633 (+)NCBI
MGSCv37763,097,441 - 63,188,003 (+)RGD
Celera753,195,732 - 53,286,248 (+)RGD
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006540729   ⟹   XP_006540792
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39755,521,604 - 55,580,446 (+)NCBI
GRCm38755,871,856 - 55,930,698 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017322067   ⟹   XP_017177556
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39755,546,468 - 55,580,448 (+)NCBI
GRCm38755,896,846 - 55,930,502 (+)NCBI
Sequence:
RefSeq Acc Id: XR_004934046
RefSeq Status:
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39755,491,556 - 55,580,448 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_035500   ⟸   NM_011370
- Peptide Label: isoform a
- UniProtKB: Q7TMB8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001158133   ⟸   NM_001164661
- Peptide Label: isoform a
- UniProtKB: Q7TMB8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001158134   ⟸   NM_001164662
- Peptide Label: isoform b
- UniProtKB: Q7TMB8 (UniProtKB/Swiss-Prot),   A0A0R4J119 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006540792   ⟸   XM_006540729
- Peptide Label: isoform X1
- UniProtKB: Q7TMB8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017177556   ⟸   XM_017322067
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSMUSP00000032629   ⟸   ENSMUST00000032629
RefSeq Acc Id: ENSMUSP00000127717   ⟸   ENSMUST00000163845
RefSeq Acc Id: ENSMUSP00000082353   ⟸   ENSMUST00000085255
RefSeq Acc Id: ENSMUSP00000146194   ⟸   ENSMUST00000206862
RefSeq Acc Id: ENSMUSP00000134509   ⟸   ENSMUST00000173783
Protein Domains
DUF1394

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q7TMB8-F1-model_v2 AlphaFold Q7TMB8 1-1253 view protein structure

Promoters
RGD ID:8664345
Promoter ID:EPDNEW_M10157
Type:initiation region
Name:Cyfip1_1
Description:Mus musculus cytoplasmic FMR1 interacting protein 1 , transcriptvariant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38755,842,286 - 55,842,346EPDNEW
RGD ID:6842052
Promoter ID:MM_KWN:50653
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Lung
Transcripts:UC009HDO.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36763,151,671 - 63,155,212 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1338801 AgrOrtholog
Ensembl Genes ENSMUSG00000030447 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000032629 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000082353 ENTREZGENE
  ENSMUSP00000082353.5 UniProtKB/TrEMBL
  ENSMUSP00000127717 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000134509.2 UniProtKB/TrEMBL
  ENSMUSP00000146194.2 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000032629 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000085255 ENTREZGENE
  ENSMUST00000085255.11 UniProtKB/TrEMBL
  ENSMUST00000163845 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000173783.8 UniProtKB/TrEMBL
  ENSMUST00000206862.2 UniProtKB/TrEMBL
InterPro Cytoplasmic_FMR1-int UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DUF1394 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:20430 UniProtKB/Swiss-Prot
MGD MGI:1338801 ENTREZGENE
NCBI Gene 20430 ENTREZGENE
PANTHER PTHR12195 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam DUF1394 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FragX_IP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Cyfip1 PhenoGen
PIRSF FMR1_interacting UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS CYTOFMRPINTP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0R4J119 ENTREZGENE, UniProtKB/TrEMBL
  A0A0U1RQ05_MOUSE UniProtKB/TrEMBL
  CYFP1_MOUSE UniProtKB/Swiss-Prot
  G3UZI5_MOUSE UniProtKB/TrEMBL
  Q7TMB8 ENTREZGENE
  Q8C8R2_MOUSE UniProtKB/TrEMBL
UniProt Secondary O88558 UniProtKB/Swiss-Prot
  Q3U7Q7 UniProtKB/Swiss-Prot
  Q5DU50 UniProtKB/Swiss-Prot
  Q7TSZ5 UniProtKB/Swiss-Prot
  Q80VN6 UniProtKB/Swiss-Prot
  Q8CE85 UniProtKB/Swiss-Prot
  Q99LY1 UniProtKB/Swiss-Prot