Zswim7 (zinc finger SWIM-type containing 7) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Zswim7 (zinc finger SWIM-type containing 7) Mus musculus
Analyze
Symbol: Zswim7
Name: zinc finger SWIM-type containing 7
RGD ID: 1321162
MGI Page MGI
Description: Predicted to enable zinc ion binding activity. Predicted to be involved in double-strand break repair via homologous recombination and protein stabilization. Predicted to act upstream of or within DNA recombination and DNA repair. Predicted to be located in nucleus. Predicted to be part of Shu complex. Human ortholog(s) of this gene implicated in 46 XX gonadal dysgenesis and spermatogenic failure. Orthologous to human ZSWIM7 (zinc finger SWIM-type containing 7).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 2410012H22Rik; MGC130274; RP23-330N10.3; SW; SWIM domain-containing and Srs2-interacting protein 1 homolog; SWS1; zinc finger SWIM domain-containing protein 7; zinc finger, SWIM-type containing 7
RGD Orthologs
Human
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391162,158,050 - 62,172,221 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1162,158,050 - 62,172,201 (-)EnsemblGRCm39 Ensembl
GRCm381162,267,224 - 62,281,395 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1162,267,224 - 62,281,375 (-)EnsemblGRCm38mm10GRCm38
MGSCv371162,080,726 - 62,094,897 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361162,083,410 - 62,097,635 (-)NCBIMGSCv36mm8
MGSCv361162,700,101 - 62,714,326 (-)NCBIMGSCv36mm8
Celera1168,110,278 - 68,111,873 (-)NCBICelera
Cytogenetic Map11B2NCBI
cM Map1137.99NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IEA)
Shu complex  (IBA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:12466305   PMID:12477932   PMID:14610273   PMID:16141072   PMID:16141073   PMID:18799693   PMID:21267068   PMID:21677750  
PMID:21873635   PMID:30305635   PMID:34253720  


Genomics

Comparative Map Data
Zswim7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391162,158,050 - 62,172,221 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1162,158,050 - 62,172,201 (-)EnsemblGRCm39 Ensembl
GRCm381162,267,224 - 62,281,395 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1162,267,224 - 62,281,375 (-)EnsemblGRCm38mm10GRCm38
MGSCv371162,080,726 - 62,094,897 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361162,083,410 - 62,097,635 (-)NCBIMGSCv36mm8
MGSCv361162,700,101 - 62,714,326 (-)NCBIMGSCv36mm8
Celera1168,110,278 - 68,111,873 (-)NCBICelera
Cytogenetic Map11B2NCBI
cM Map1137.99NCBI
ZSWIM7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381715,976,560 - 15,999,704 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1715,976,560 - 15,999,717 (-)EnsemblGRCh38hg38GRCh38
GRCh371715,879,874 - 15,903,018 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361715,820,599 - 15,843,731 (-)NCBINCBI36Build 36hg18NCBI36
Celera1715,782,880 - 15,806,013 (-)NCBICelera
Cytogenetic Map17p12NCBI
HuRef1715,747,186 - 15,770,054 (-)NCBIHuRef
CHM1_11715,888,634 - 15,912,292 (-)NCBICHM1_1
T2T-CHM13v2.01715,878,745 - 15,901,920 (-)NCBIT2T-CHM13v2.0
Zswim7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81047,456,843 - 47,469,084 (-)NCBIGRCr8
mRatBN7.21046,953,311 - 46,969,800 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1046,957,525 - 46,969,671 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1051,661,311 - 51,673,404 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01051,151,861 - 51,163,954 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01046,655,269 - 46,667,362 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01048,587,117 - 48,599,208 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1048,587,119 - 48,599,208 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01048,375,622 - 48,387,713 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41048,438,718 - 48,450,809 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11048,452,340 - 48,464,513 (-)NCBI
Celera1046,203,432 - 46,215,523 (-)NCBICelera
Cytogenetic Map10q23NCBI
Zswim7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554671,364,372 - 1,381,083 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554671,364,044 - 1,381,101 (-)NCBIChiLan1.0ChiLan1.0
ZSWIM7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1539,868,086 - 39,883,693 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl539,868,123 - 39,882,557 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha540,014,407 - 40,030,556 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0539,977,876 - 39,994,037 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl539,977,936 - 39,992,776 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1539,950,116 - 39,966,264 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0539,895,384 - 39,911,528 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0540,086,652 - 40,102,800 (+)NCBIUU_Cfam_GSD_1.0
Zswim7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560259,226,416 - 59,244,847 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936821567,439 - 582,458 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936821567,397 - 582,177 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZSWIM7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1259,418,924 - 59,436,604 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11259,418,905 - 59,434,689 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
ZSWIM7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11615,662,268 - 15,681,875 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1615,662,215 - 15,681,561 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660595,278,752 - 5,298,460 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Zswim7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248774,404,345 - 4,420,079 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248774,404,174 - 4,427,085 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Zswim7
556 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:130
Count of miRNA genes:119
Interacting mature miRNAs:123
Transcripts:ENSMUST00000072916
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884446Sklq10_mskull length QTL 10, 10 week (mouse)11325000062890826Mouse
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11325000072690826Mouse
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
26884401Huml4_mhumerus length 4, 10 week (mouse)111155000068490826Mouse
27226762Feml21_mfemur length 21, 16 week (mouse)111175000065990826Mouse
1357640Orq2_movulation rate QTL 2 (mouse)Not determined111226863768500330Mouse
4141127W3q4_mweight 3 weeks QTL 4 (mouse)Not determined1226863768500330Mouse
4141470Egq4_mearly growth QTL 4 (mouse)Not determined1226863768500330Mouse
4142109W10q2_mweight 10 weeks QTL 2 (mouse)Not determined1226863768500330Mouse
4141582Lgaq1_mlate growth adjusted QTL 1 (mouse)Not determined1226863768500330Mouse
4142308W6q3_mweight 6 weeks QTL 3 (mouse)Not determined111226863768500330Mouse
4142216Lgq1_mlate growth QTL 1 (mouse)Not determined1226863768500330Mouse
4141966Tailq1_mtail length QTL 1 (mouse)Not determined1226863768500330Mouse
1357851Scfq3_msubcutaneous fat pad weight QTL 3 (mouse)Not determined111226863768500330Mouse
1357720Kidpq1_mkidney weight percentage QTL 1 (mouse)Not determined111226863768500330Mouse
1357437Epfq4_mepididymal fat pad weight QTL 4 (mouse)Not determined111226863768500330Mouse
1559002Lmrq4_mLeishmania major resistance QTL 4 (mouse)Not determined111226863769684947Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
1558945Orgwq8_morgan weight QTL 8 (mouse)Not determined111705617567078411Mouse
10053687Eae6_msusceptibility to experimental allergic encephalomyelitis 6 (mouse)Not determined111778196668500330Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1912420496897826Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112180736495881231Mouse
1357844Si5lq5_mserum IGFBP-5 level QTL 5 (mouse)Not determined112816587362165976Mouse
13524848Ppiq7_mprepulse inhibition QTL 7 (mouse)112856914762569147Mouse
1301426Desp2_mdespair 2 (mouse)Not determined112870858162708700Mouse
11522752Cocia18_mcocaine-induced activity, QTL 18 (mouse)113100820965008209Mouse
11059563Lmr31_mleishmaniasis resistance 31 (mouse)113210057766100694Mouse
1357782Char8_mP. chabaudi malaria resistance QTL 8 (mouse)Not determined113557861669684987Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113589082784890826Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113628257783481356Mouse
1301788Lbw8_mlupus NZB x NZW 8 (mouse)Not determined113650328770509492Mouse
1301896Tria1_mT-cell receptor induced activation 1 (mouse)Not determined113661356570613855Mouse
4141853Skmw17_mskeletal muscle weight 17 (mouse)Not determined113708094171081064Mouse
10766457Nwa3_mNew Zealand White autoimmunity 3 (mouse)113801611572016209Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114225661776256730Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114225661776256730Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114463003876854757Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114516587379978324Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114570858189818733Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114618516780185262Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114631940780319522Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115007819184078411Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115249438586494385Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115339058887390737Mouse
4141084Spqq1_msperm quality QTL 1 (mouse)Not determined5406567063319522Mouse
1302186Blmpf2_mbleomycin-induced pulmonary fibrosis 2 (mouse)Not determined115406567067078411Mouse
4142148Ckdbp2_mchronic kidney disease blood pressure locus 2 (mouse)Not determined115408094165103841Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115412675283733652Mouse
4141875Etax9_methanol induced ataxia 9 (mouse)Not determined5528498572209927Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156864027114157957Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115775466091754758Mouse
10053682Eae45_mexperimental allergic encephalomyelitis susceptibility 45 (mouse)Not determined115849055574754758Mouse
1300924Ity2_mimmunity to S. typhimurium 2 (mouse)Not determined15850803087695238Mouse
4141982Skts-fp2_mskin tumor susceptibility in FVB and PWK 2 (mouse)Not determined5871926685066529Mouse
11532697Sluc36_msusceptibility to lung cancer 36 (mouse)115925661769482699Mouse
1301987Pid3_mprior incubation determinant 3 (mouse)Not determined116168682088699728Mouse
1301319Dautb4_mdopamine uptake transporter binding 4 (mouse)Not determined116215600596156153Mouse


Expression


Sequence


RefSeq Acc Id: ENSMUST00000072916   ⟹   ENSMUSP00000072688
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1162,158,050 - 62,172,201 (-)Ensembl
GRCm38.p6 Ensembl1162,267,224 - 62,281,375 (-)Ensembl
RefSeq Acc Id: NM_027198   ⟹   NP_081474
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391162,158,050 - 62,172,221 (-)NCBI
GRCm381162,267,224 - 62,281,395 (-)ENTREZGENE
MGSCv371162,080,726 - 62,094,897 (-)RGD
Celera1168,110,278 - 68,111,873 (-)ENTREZGENE
cM Map11 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_081474 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI09344 (Get FASTA)   NCBI Sequence Viewer  
  BAB26965 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000072688
  ENSMUSP00000072688.5
GenBank Protein Q9CWQ2 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_081474   ⟸   NM_027198
- UniProtKB: Q9CWQ2 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000072688   ⟸   ENSMUST00000072916

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9CWQ2-F1-model_v2 AlphaFold Q9CWQ2 1-152 view protein structure

Promoters
RGD ID:6822396
Promoter ID:MM_KWN:7808
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000037997,   NM_027198,   NM_029704,   OTTMUST00000013013,   UC007JIS.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361162,094,321 - 62,095,022 (+)MPROMDB
RGD ID:8674964
Promoter ID:EPDNEW_M15512
Type:initiation region
Name:Zswim7_1
Description:Mus musculus zinc finger SWIM-type containing 7 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381162,281,372 - 62,281,432EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1916997 AgrOrtholog
Ensembl Genes ENSMUSG00000014243 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000072916 ENTREZGENE
  ENSMUST00000072916.5 UniProtKB/Swiss-Prot
InterPro Znf_SWIM UniProtKB/Swiss-Prot
KEGG Report mmu:69747 UniProtKB/Swiss-Prot
MGD MGI:1916997 ENTREZGENE
NCBI Gene 69747 ENTREZGENE
PANTHER ZINC FINGER SWIM DOMAIN-CONTAINING PROTEIN 7 UniProtKB/Swiss-Prot
  ZINC FINGER SWIM DOMAIN-CONTAINING PROTEIN 7 UniProtKB/Swiss-Prot
Pfam SWIM UniProtKB/Swiss-Prot
PhenoGen Zswim7 PhenoGen
PROSITE ZF_SWIM UniProtKB/Swiss-Prot
UniProt Q9CWQ2 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-11-27 Zswim7  zinc finger SWIM-type containing 7    zinc finger, SWIM-type containing 7  Symbol and/or name change 5135510 APPROVED