Cfap69 (cilia and flagella associated protein 69) - Rat Genome Database

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Gene: Cfap69 (cilia and flagella associated protein 69) Mus musculus
Analyze
Symbol: Cfap69
Name: cilia and flagella associated protein 69
RGD ID: 1321066
MGI Page MGI
Description: Involved in several processes, including positive regulation of fertilization; response to odorant; and sperm axoneme assembly. Localizes to non-motile cilium. Is expressed in several structures, including brain; genitourinary system; gut gland; nasal cavity epithelium; and spinal cord ventricular layer. Used to study spermatogenic failure 24. Human ortholog(s) of this gene implicated in spermatogenic failure 24. Orthologous to human CFAP69 (cilia and flagella associated protein 69); INTERACTS WITH 4,4'-sulfonyldiphenol; bis(2-ethylhexyl) phthalate; dibenz[a,h]anthracene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 4921525K03; A330021E22Rik; AI427898; cilia- and flagella-associated protein 69; hypothetical protein LOC207686; uncharacterized protein C7orf63 homolog
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3955,629,284 - 5,714,232 (-)NCBIGRCm39mm39
GRCm39 Ensembl55,629,278 - 5,714,239 (-)Ensembl
GRCm3855,579,278 - 5,664,232 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl55,579,278 - 5,664,239 (-)EnsemblGRCm38mm10GRCm38
MGSCv3755,580,982 - 5,664,232 (-)NCBIGRCm37mm9NCBIm37
MGSCv3655,586,988 - 5,670,238 (-)NCBImm8
Celera55,527,663 - 5,605,661 (-)NCBICelera
Cytogenetic Map5A1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
1. RGD automated import pipeline
2. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:16141072   PMID:16141073   PMID:17971504   PMID:21267068   PMID:21677750   PMID:21873635  
PMID:24194600   PMID:27626380   PMID:28495971   PMID:29606301   PMID:30415212  


Genomics

Comparative Map Data
Cfap69
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3955,629,284 - 5,714,232 (-)NCBIGRCm39mm39
GRCm39 Ensembl55,629,278 - 5,714,239 (-)Ensembl
GRCm3855,579,278 - 5,664,232 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl55,579,278 - 5,664,239 (-)EnsemblGRCm38mm10GRCm38
MGSCv3755,580,982 - 5,664,232 (-)NCBIGRCm37mm9NCBIm37
MGSCv3655,586,988 - 5,670,238 (-)NCBImm8
Celera55,527,663 - 5,605,661 (-)NCBICelera
Cytogenetic Map5A1NCBI
CFAP69
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl790,245,174 - 90,311,063 (+)EnsemblGRCh38hg38GRCh38
GRCh38790,245,174 - 90,320,964 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37789,874,488 - 89,940,377 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36789,712,461 - 89,777,624 (+)NCBINCBI36hg18NCBI36
Celera784,578,592 - 84,644,463 (+)NCBI
Cytogenetic Map7q21.13NCBI
HuRef784,484,583 - 84,549,528 (+)NCBIHuRef
CHM1_1789,804,453 - 89,870,457 (+)NCBICHM1_1
CRA_TCAGchr7v2789,205,264 - 89,271,137 (+)NCBI
Cfap69
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2428,379,604 - 28,452,562 (+)NCBI
Rnor_6.0 Ensembl425,538,497 - 25,609,652 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0425,538,513 - 25,611,470 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0425,445,683 - 25,518,638 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4425,065,221 - 25,136,471 (+)NCBIRGSC3.4rn4RGSC3.4
Celera423,824,221 - 23,897,166 (+)NCBICelera
Cytogenetic Map4q13NCBI
Cfap69
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554327,501,642 - 7,571,373 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554327,501,908 - 7,569,799 (+)NCBIChiLan1.0ChiLan1.0
CFAP69
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1795,856,393 - 95,936,535 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl795,856,393 - 95,922,012 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0782,254,266 - 82,353,873 (+)NCBIMhudiblu_PPA_v0panPan3
CFAP69
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11416,154,334 - 16,209,776 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1416,154,562 - 16,209,858 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1415,724,650 - 15,780,123 (+)NCBI
ROS_Cfam_1.01415,960,297 - 16,015,368 (+)NCBI
UMICH_Zoey_3.11416,120,881 - 16,175,655 (+)NCBI
UNSW_CanFamBas_1.01415,839,436 - 15,894,879 (+)NCBI
UU_Cfam_GSD_1.01416,125,476 - 16,180,557 (+)NCBI
Cfap69
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511829,596,409 - 29,674,545 (+)NCBI
SpeTri2.0NW_0049366213,704,718 - 3,772,298 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CFAP69
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl970,335,206 - 70,430,389 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1970,373,422 - 70,430,383 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2976,943,275 - 76,989,743 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CFAP69
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12158,617,190 - 58,684,179 (-)NCBI
Vero_WHO_p1.0NW_02366604245,541,072 - 45,608,062 (+)NCBI
Cfap69
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248092,916,614 - 2,947,817 (-)NCBI

Position Markers
AI427898  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3855,581,220 - 5,581,301UniSTSGRCm38
MGSCv3755,581,220 - 5,581,301UniSTSGRCm37
Celera55,527,901 - 5,527,982UniSTS
Cytogenetic Map5A1UniSTS
Whitehead/MRC_RH5117.72UniSTS
A330021E22Rik  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3855,580,486 - 5,581,345UniSTSGRCm38
MGSCv3755,580,486 - 5,581,345UniSTSGRCm37
Celera55,527,167 - 5,528,026UniSTS
Cytogenetic Map5A1UniSTS
cM Map5 UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4141234Pbwg14_mpostnatal body weight growth 14 (mouse)Not determined5121223552Mouse
1301468Eye1_meye weight 1 (mouse)Not determined5121879650Mouse
10412081Bwq13_mbody weight QTL 13 (mouse)Not determined5123556323Mouse
12904958Gmmq8_mgastrocnemius muscle mass QTL 8 (mouse)5129371157Mouse
10401122Pgia41_mproteoglycan induced arthritis 41 (mouse)Not determined561814634618282Mouse
15039371Nmrs21_mNAFLD-associated magnetic resonance shift 21 (mouse)5329982537299825Mouse
13442491Mecth1_mmechanosensation threshold 1 (mouse)5446800019630000Mouse
1301806Actd2_mactivity-distance traveled 2 (mouse)Not determined5517952239179654Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1783
Count of miRNA genes:718
Interacting mature miRNAs:936
Transcripts:ENSMUST00000054865, ENSMUST00000061008, ENSMUST00000124734, ENSMUST00000132510, ENSMUST00000135252, ENSMUST00000148193, ENSMUST00000148347, ENSMUST00000150140, ENSMUST00000155048
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000054865   ⟹   ENSMUSP00000053206
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl55,579,278 - 5,664,239 (-)Ensembl
RefSeq Acc Id: ENSMUST00000061008   ⟹   ENSMUSP00000051741
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl55,589,175 - 5,664,208 (-)Ensembl
RefSeq Acc Id: ENSMUST00000124734   ⟹   ENSMUSP00000119859
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl55,581,128 - 5,587,211 (-)Ensembl
RefSeq Acc Id: ENSMUST00000132510   ⟹   ENSMUSP00000122569
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl55,586,356 - 5,664,043 (-)Ensembl
RefSeq Acc Id: ENSMUST00000135252   ⟹   ENSMUSP00000117518
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl55,593,646 - 5,664,232 (-)Ensembl
RefSeq Acc Id: ENSMUST00000148193   ⟹   ENSMUSP00000114623
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl55,649,808 - 5,663,292 (-)Ensembl
RefSeq Acc Id: ENSMUST00000148347   ⟹   ENSMUSP00000119944
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl55,581,171 - 5,617,289 (-)Ensembl
RefSeq Acc Id: ENSMUST00000150140
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl55,625,722 - 5,626,095 (-)Ensembl
RefSeq Acc Id: ENSMUST00000155048   ⟹   ENSMUSP00000120771
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl55,581,038 - 5,582,501 (-)Ensembl
RefSeq Acc Id: ENSMUST00000196165   ⟹   ENSMUSP00000143393
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl55,579,282 - 5,664,208 (-)Ensembl
RefSeq Acc Id: ENSMUST00000198121
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl55,646,830 - 5,664,227 (-)Ensembl
RefSeq Acc Id: ENSMUST00000199314
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl55,580,982 - 5,622,179 (-)Ensembl
RefSeq Acc Id: NM_172447   ⟹   NP_766035
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3955,630,982 - 5,714,232 (-)NCBI
GRCm3855,580,982 - 5,664,232 (-)NCBI
MGSCv3755,580,982 - 5,664,232 (-)RGD
Celera55,527,663 - 5,605,661 (-)RGD
cM Map5 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006503560   ⟹   XP_006503623
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3955,629,284 - 5,713,659 (-)NCBI
GRCm3855,579,278 - 5,663,660 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011240666   ⟹   XP_011238968
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3955,629,284 - 5,697,023 (-)NCBI
GRCm3855,579,278 - 5,647,023 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_766035   ⟸   NM_172447
- UniProtKB: Q8BH53 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006503623   ⟸   XM_006503560
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_011238968   ⟸   XM_011240666
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSMUSP00000119859   ⟸   ENSMUST00000124734
RefSeq Acc Id: ENSMUSP00000053206   ⟸   ENSMUST00000054865
RefSeq Acc Id: ENSMUSP00000122569   ⟸   ENSMUST00000132510
RefSeq Acc Id: ENSMUSP00000117518   ⟸   ENSMUST00000135252
RefSeq Acc Id: ENSMUSP00000119944   ⟸   ENSMUST00000148347
RefSeq Acc Id: ENSMUSP00000114623   ⟸   ENSMUST00000148193
RefSeq Acc Id: ENSMUSP00000051741   ⟸   ENSMUST00000061008
RefSeq Acc Id: ENSMUSP00000143393   ⟸   ENSMUST00000196165
RefSeq Acc Id: ENSMUSP00000120771   ⟸   ENSMUST00000155048

Promoters
RGD ID:6836866
Promoter ID:MM_KWN:41308
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Kidney,   MEF_B4,   MEF_B6
Transcripts:OTTMUST00000063959,   OTTMUST00000063960,   OTTMUST00000084622,   UC008WIV.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3655,663,974 - 5,664,474 (-)MPROMDB
RGD ID:6885938
Promoter ID:EPDNEW_M6419
Type:initiation region
Name:Cfap69_1
Description:Mus musculus cilia and flagella associated protein 69 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3855,664,203 - 5,664,263EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2443778 AgrOrtholog
Ensembl Genes ENSMUSG00000040473 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000051741 UniProtKB/TrEMBL
  ENSMUSP00000053206 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000114623 UniProtKB/TrEMBL
  ENSMUSP00000117518 UniProtKB/Swiss-Prot
  ENSMUSP00000119859 UniProtKB/TrEMBL
  ENSMUSP00000119944 UniProtKB/TrEMBL
  ENSMUSP00000120771 UniProtKB/TrEMBL
  ENSMUSP00000122569 UniProtKB/TrEMBL
  ENSMUSP00000143393 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000054865 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000061008 UniProtKB/TrEMBL
  ENSMUST00000124734 UniProtKB/TrEMBL
  ENSMUST00000132510 UniProtKB/TrEMBL
  ENSMUST00000135252 UniProtKB/Swiss-Prot
  ENSMUST00000148193 UniProtKB/TrEMBL
  ENSMUST00000148347 UniProtKB/TrEMBL
  ENSMUST00000155048 UniProtKB/TrEMBL
  ENSMUST00000196165 UniProtKB/TrEMBL
InterPro ARM-type_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:207686 UniProtKB/Swiss-Prot
MGD MGI:2443778 ENTREZGENE
NCBI Gene 207686 ENTREZGENE
PhenoGen Cfap69 PhenoGen
Superfamily-SCOP SSF48371 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JG21_MOUSE UniProtKB/TrEMBL
  CFA69_MOUSE UniProtKB/Swiss-Prot
  D3YV72_MOUSE UniProtKB/TrEMBL
  D6RFV9_MOUSE UniProtKB/TrEMBL
  F6Q7Y3_MOUSE UniProtKB/TrEMBL
  F6S241_MOUSE UniProtKB/TrEMBL
  F6WCD2_MOUSE UniProtKB/TrEMBL
  G3X999_MOUSE UniProtKB/TrEMBL
  Q8BH53 ENTREZGENE
UniProt Secondary Q3TPR3 UniProtKB/Swiss-Prot
  Q8CA81 UniProtKB/Swiss-Prot
  Q8CDU8 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-08-20 Cfap69  cilia and flagella associated protein 69  A330021E22Rik  RIKEN cDNA A330021E22 gene  Symbol and/or name change 5135510 APPROVED