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Gene: CDC42EP2 (CDC42 effector protein 2) Homo sapiens
Symbol: CDC42EP2
Name: CDC42 effector protein 2
RGD ID: 1321045
Description: Exhibits GTP-Rho binding activity and GTPase activator activity. Involved in actin cytoskeleton organization; positive regulation of cellular component biogenesis; and regulation of cell shape. Localizes to cytosol; microtubule cytoskeleton; and plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: binder of Rho GTPases 1; BORG1; CDC42 effector protein (Rho GTPase binding) 2; CEP2; CRIB-containing BOGR1 protein
Mus musculus (house mouse) : Cdc42ep2 (CDC42 effector protein (Rho GTPase binding) 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cdc42ep2 (CDC42 effector protein 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cdc42ep2 (CDC42 effector protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CDC42EP2 (CDC42 effector protein 2)
Canis lupus familiaris (dog) : CDC42EP2 (CDC42 effector protein 2)
Sus scrofa (pig) : CDC42EP2 (CDC42 effector protein 2)
Chlorocebus sabaeus (African green monkey) : CDC42EP2 (CDC42 effector protein 2)
Heterocephalus glaber (naked mole-rat) : Cdc42ep2 (CDC42 effector protein 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl1165,314,866 - 65,322,417 (+)EnsemblGRCh38hg38GRCh38
GRCh381165,314,866 - 65,322,417 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371165,082,289 - 65,089,900 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361164,838,907 - 64,846,476 (+)NCBINCBI36hg18NCBI36
Build 341164,838,906 - 64,846,475NCBI
Celera1162,408,688 - 62,416,256 (+)NCBI
Cytogenetic Map11q13.1NCBI
HuRef1161,409,324 - 61,416,936 (+)NCBIHuRef
CHM1_11164,966,301 - 64,973,912 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on CDC42EP2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1321045
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.