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Gene: Bloc1s6 (biogenesis of lysosomal organelles complex-1, subunit 6, pallidin) Mus musculus
Symbol: Bloc1s6
Name: biogenesis of lysosomal organelles complex-1, subunit 6, pallidin
Description: Predicted to have actin filament binding activity and protein homodimerization activity. Involved in several processes, including anterograde synaptic vesicle transport; positive regulation of natural killer cell activation; and secretion of lysosomal enzymes. Localizes to the BLOC-1 complex and endosome. Predicted to colocalize with the SNARE complex. Used to study Hermansky-Pudlak syndrome 9; platelet storage pool deficiency; and pulmonary emphysema. Human ortholog(s) of this gene implicated in Hermansky-Pudlak syndrome 9. Is expressed in brain; spinal cord; and thoracic ganglion. Orthologous to human BLOC1S6 (biogenesis of lysosomal organelles complex 1 subunit 6); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: biogenesis of lysosome-related organelles complex 1 subunit 6; biogenesis of organelles complex-1, subunit 6, pallidin; BLOC-1; BLOC-1 subunit; BLOC-1 subunit 6; pa; pallid protein; pallidin; Pldn; Stx13bp1; syntaxin 13 binding protein 1; syntaxin 13-interacting protein pallid
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl2122,738,503 - 122,749,475 (+)Ensembl
GRCm382122,738,505 - 122,749,487 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372122,564,241 - 122,575,223 (+)NCBIGRCm37mm9NCBIm37
MGSCv362122,429,955 - 122,439,540 (+)NCBImm8
Celera2123,933,064 - 123,944,057 (+)NCBICelera
Cytogenetic Map2 E5NCBI
cM Map260.66NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Bloc1s6
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1320976
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.