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Gene: SNX5 (sorting nexin 5) Homo sapiens
Symbol: SNX5
Name: sorting nexin 5
Description: Exhibits dynactin binding activity and phosphatidylinositol binding activity. Involved in several processes, including pinocytosis; positive regulation of insulin receptor signaling pathway; and retrograde transport, endosome to Golgi. Localizes to several cellular components, including endosome; extrinsic component of cytoplasmic side of plasma membrane; and retromer complex. Colocalizes with early endosome membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FLJ10931; sorting nexin-5
Mus musculus (house mouse) : Snx5 (sorting nexin 5)  MGI  Alliance
Rattus norvegicus (Norway rat) : Snx5 (sorting nexin 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Snx5 (sorting nexin 5)
Pan paniscus (bonobo/pygmy chimpanzee) : SNX5 (sorting nexin 5)
Canis lupus familiaris (dog) : SNX5 (sorting nexin 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Snx5 (sorting nexin 5)
Sus scrofa (pig) : SNX5 (sorting nexin 5)
Chlorocebus sabaeus (African green monkey) : SNX5 (sorting nexin 5)
Heterocephalus glaber (naked mole-rat) : Snx5 (sorting nexin 5)
more info ...
Related Pseudogenes: SNX5P1   SNX5P2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl2017,941,597 - 17,968,980 (-)EnsemblGRCh38hg38GRCh38
GRCh382017,941,600 - 17,968,794 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372017,922,244 - 17,949,490 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362017,870,244 - 17,897,490 (-)NCBINCBI36hg18NCBI36
Build 342017,870,245 - 17,897,490NCBI
Celera2017,996,791 - 18,024,035 (-)NCBI
Cytogenetic Map20p11.23NCBI
HuRef2017,885,114 - 17,912,355 (-)NCBIHuRef
CHM1_12017,922,261 - 17,949,657 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on SNX5
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1320945
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.