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Gene: HOOK2 (hook microtubule tethering protein 2) Homo sapiens
Symbol: HOOK2
Name: hook microtubule tethering protein 2
Description: Hook proteins are cytosolic coiled-coil proteins that contain conserved N-terminal domains, which attach to microtubules, and more divergent C-terminal domains, which mediate binding to organelles. The Drosophila Hook protein is a component of the endocytic compartment.[supplied by OMIM, Apr 2004]
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: FLJ26218; h-hook2; hHK2; HK2; hook homolog 2; hook microtubule-tethering protein 2
Mus musculus (house mouse) : Hook2 (hook microtubule tethering protein 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Hook2 (hook microtubule-tethering protein 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hook2 (hook microtubule tethering protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : HOOK2 (hook microtubule tethering protein 2)
Canis lupus familiaris (dog) : HOOK2 (hook microtubule tethering protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hook2 (hook microtubule tethering protein 2)
Sus scrofa (pig) : HOOK2 (hook microtubule tethering protein 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381912,763,002 - 12,778,484 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371912,873,817 - 12,889,248 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361912,734,817 - 12,747,434 (-)NCBINCBI36hg18NCBI36
Build 341912,734,816 - 12,747,337NCBI
Celera1912,763,527 - 12,776,144 (-)NCBI
Cytogenetic Map19p13.13NCBI
HuRef1912,446,753 - 12,459,369 (-)NCBIHuRef
CHM1_11912,874,278 - 12,886,908 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on HOOK2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1320916
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.