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Gene: ZFYVE28 (zinc finger FYVE-type containing 28) Homo sapiens
Symbol: ZFYVE28
Name: zinc finger FYVE-type containing 28
Description: Exhibits phosphatidylinositol-3-phosphate binding activity. Involved in negative regulation of epidermal growth factor-activated receptor activity. Localizes to cytosol and early endosome membrane; INTERACTS WITH 17beta-estradiol; 3-isobutyl-1-methyl-7H-xanthine; 5-aza-2'-deoxycytidine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: hLst2; lateral signaling target protein 2 homolog; lateral signaling target-2 homolog; lst-2; LST2; LYST2; MGC43699; MGC61592; zinc finger FYVE domain-containing protein 28; zinc finger, FYVE domain containing 28
Mus musculus (house mouse) : Zfyve28 (zinc finger, FYVE domain containing 28)  MGI  Alliance
Rattus norvegicus (Norway rat) : Zfyve28 (zinc finger FYVE-type containing 28)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Zfyve28 (zinc finger FYVE-type containing 28)
Pan paniscus (bonobo/pygmy chimpanzee) : ZFYVE28 (zinc finger FYVE-type containing 28)
Canis lupus familiaris (dog) : ZFYVE28 (zinc finger FYVE-type containing 28)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Zfyve28 (zinc finger FYVE-type containing 28)
Sus scrofa (pig) : ZFYVE28 (zinc finger FYVE-type containing 28)
Chlorocebus sabaeus (African green monkey) : ZFYVE28 (zinc finger FYVE-type containing 28)
Heterocephalus glaber (naked mole-rat) : Zfyve28 (zinc finger FYVE-type containing 28)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl42,269,582 - 2,418,663 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl42,269,582 - 2,418,651 (-)EnsemblGRCh38hg38GRCh38
GRCh3842,269,585 - 2,418,698 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3742,271,324 - 2,420,370 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3642,241,123 - 2,390,167 (-)NCBINCBI36hg18NCBI36
Celera42,183,673 - 2,332,010 (-)NCBI
Cytogenetic Map4p16.3NCBI
HuRef42,212,291 - 2,360,820 (-)NCBIHuRef
CHM1_142,269,829 - 2,418,537 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on ZFYVE28
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1320885
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.