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Gene: SNX25 (sorting nexin 25) Homo sapiens
Symbol: SNX25
Name: sorting nexin 25
Description: Predicted to have phosphatidylinositol binding activity and type I transforming growth factor beta receptor binding activity. Involved in negative regulation of pathway-restricted SMAD protein phosphorylation; negative regulation of transforming growth factor beta receptor signaling pathway; and receptor catabolic process. Localizes to intracellular membrane-bounded organelle; INTERACTS WITH (-)-epigallocatechin 3-gallate; 17beta-hydroxy-5alpha-androstan-3-one; aflatoxin B2.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: FLJ23161; MSTP043; SBBI31; sorting nexin-25
Mus musculus (house mouse) : Snx25 (sorting nexin 25)  MGI  Alliance
Rattus norvegicus (Norway rat) : Snx25 (sorting nexin 25)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Snx25 (sorting nexin 25)
Pan paniscus (bonobo/pygmy chimpanzee) : SNX25 (sorting nexin 25)
Canis lupus familiaris (dog) : SNX25 (sorting nexin 25)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Snx25 (sorting nexin 25)
Sus scrofa (pig) : SNX25 (sorting nexin 25)
Chlorocebus sabaeus (African green monkey) : SNX25 (sorting nexin 25)
Heterocephalus glaber (naked mole-rat) : Snx25 (sorting nexin 25)
more info ...
Related Pseudogenes: SNX25P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl4185,204,237 - 185,370,185 (+)EnsemblGRCh38hg38GRCh38
GRCh384185,204,237 - 185,368,020 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh374186,130,773 - 186,285,120 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364186,368,278 - 186,522,114 (+)NCBINCBI36hg18NCBI36
Build 344186,506,432 - 186,660,267NCBI
Celera4183,458,214 - 183,611,271 (+)NCBI
Cytogenetic Map4q35.1NCBI
HuRef4181,885,306 - 182,038,630 (+)NCBIHuRef
CHM1_14186,101,907 - 186,261,556 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on SNX25
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1320883
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.