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Gene: MTAP (methylthioadenosine phosphorylase) Homo sapiens
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Symbol: MTAP
Name: methylthioadenosine phosphorylase
Description: Predicted to have S-methyl-5-thioadenosine phosphorylase activity. Predicted to be involved in L-methionine salvage from methylthioadenosine. Localizes to the cytosol. Implicated in biliary tract benign neoplasm. Biomarker of common bile duct neoplasm and pancreatic cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 5'-methylthioadenosine phosphorylase; BDMF; c86fus; DMSFH; DMSMFH; epididymis luminal protein 249; HEL-249; LGMBF; MeSAdo phosphorylase; MSAP; MTA phosphorylase; MTAPase; S-methyl-5'-thioadenosine phosphorylase
Orthologs:
Mus musculus (house mouse) : Mtap (methylthioadenosine phosphorylase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Mtap (methylthioadenosine phosphorylase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mtap (methylthioadenosine phosphorylase)
Pan paniscus (bonobo/pygmy chimpanzee) : MTAP (methylthioadenosine phosphorylase)
Canis lupus familiaris (dog) : MTAP (methylthioadenosine phosphorylase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mtap (methylthioadenosine phosphorylase)
Sus scrofa (pig) : MTAP (methylthioadenosine phosphorylase)
more info ...
Related Pseudogenes: MTAPP1   MTAPP2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38921,802,636 - 21,867,081 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37921,802,635 - 21,941,040 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36921,792,635 - 21,855,970 (+)NCBINCBI36hg18NCBI36
Build 34921,792,634 - 21,855,967NCBI
Celera921,740,998 - 21,804,334 (+)NCBI
Cytogenetic Map9p21.3NCBI
HuRef921,765,963 - 21,829,332 (+)NCBIHuRef
CHM1_1921,802,515 - 21,865,858 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on MTAP
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1320830
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.