Cwf19l2 (CWF19 like cell cycle control factor 2) - Rat Genome Database

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Gene: Cwf19l2 (CWF19 like cell cycle control factor 2) Mus musculus
Analyze
Symbol: Cwf19l2
Name: CWF19 like cell cycle control factor 2 (Ensembl:CWF19-like 2, cell cycle control (S. pombe))
RGD ID: 1320785
MGI Page MGI
Description: Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be part of post-mRNA release spliceosomal complex. Orthologous to human CWF19L2 (CWF19 like cell cycle control factor 2).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 3230401L03Rik; 9030209E10; CWF19-like 2, cell cycle control; CWF19-like 2, cell cycle control (S. pombe); CWF19-like protein 2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3993,403,592 - 3,479,236 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl93,403,592 - 3,479,236 (+)EnsemblGRCm39 Ensembl
GRCm3893,403,592 - 3,479,236 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl93,403,592 - 3,479,236 (+)EnsemblGRCm38mm10GRCm38
MGSCv3793,404,085 - 3,479,236 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3693,404,085 - 3,479,236 (+)NCBIMGSCv36mm8
Celera3119,215,796 - 119,285,730 (-)NCBICelera
Cytogenetic Map9A1NCBI
cM Map92.06NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
3. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Database resources of the National Center for Biotechnology Information. Wheeler DL, etal., Nucleic Acids Res 2001 Jan 1;29(1):11-6.
Additional References at PubMed
PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:12477932   PMID:12520002   PMID:12904583   PMID:14610273   PMID:16141072   PMID:16141073   PMID:18799693   PMID:21267068  
PMID:21873635   PMID:30196744   PMID:32325033  


Genomics

Comparative Map Data
Cwf19l2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3993,403,592 - 3,479,236 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl93,403,592 - 3,479,236 (+)EnsemblGRCm39 Ensembl
GRCm3893,403,592 - 3,479,236 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl93,403,592 - 3,479,236 (+)EnsemblGRCm38mm10GRCm38
MGSCv3793,404,085 - 3,479,236 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3693,404,085 - 3,479,236 (+)NCBIMGSCv36mm8
Celera3119,215,796 - 119,285,730 (-)NCBICelera
Cytogenetic Map9A1NCBI
cM Map92.06NCBI
CWF19L2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811107,326,360 - 107,457,825 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11107,326,360 - 107,457,825 (-)EnsemblGRCh38hg38GRCh38
GRCh3711107,197,086 - 107,328,551 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611106,702,293 - 106,830,406 (-)NCBINCBI36Build 36hg18NCBI36
Build 3411106,702,292 - 106,830,406NCBI
Celera11104,362,890 - 104,483,437 (-)NCBICelera
Cytogenetic Map11q22.3NCBI
HuRef11103,133,370 - 103,254,160 (-)NCBIHuRef
CHM1_111107,080,175 - 107,211,650 (-)NCBICHM1_1
T2T-CHM13v2.011107,333,512 - 107,464,989 (-)NCBIT2T-CHM13v2.0
Cwf19l2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr866,036,158 - 6,102,686 (-)NCBIGRCr8
mRatBN7.26290,148 - 356,636 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6281,685 - 356,604 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6506,515 - 572,953 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06815,805 - 882,242 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06340,227 - 406,631 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0618,970,616 - 19,037,176 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl618,970,564 - 19,055,924 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0628,868,716 - 28,935,276 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47418,368 - 485,802 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17418,367 - 482,123 (+)NCBI
Celera6115,555 - 181,554 (-)NCBICelera
Cytogenetic Map6q11NCBI
Cwf19l2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554129,766,910 - 9,861,027 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554129,758,751 - 9,861,019 (-)NCBIChiLan1.0ChiLan1.0
CWF19L2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29108,025,853 - 108,203,804 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111109,157,101 - 109,297,820 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011102,219,339 - 102,345,865 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111105,702,934 - 105,828,168 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11105,702,934 - 105,828,149 (-)Ensemblpanpan1.1panPan2
CWF19L2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1524,936,700 - 25,080,927 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl524,833,373 - 25,080,451 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha524,852,125 - 25,005,758 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0524,963,467 - 25,107,620 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl524,963,519 - 25,107,618 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1525,015,519 - 25,159,677 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0524,902,624 - 25,047,003 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0524,964,115 - 25,111,783 (+)NCBIUU_Cfam_GSD_1.0
Cwf19l2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494790,229,976 - 90,343,408 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365511,193,109 - 1,306,533 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CWF19L2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl935,967,204 - 36,059,749 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1935,967,198 - 36,059,780 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2940,006,188 - 40,106,971 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CWF19L2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1198,749,892 - 98,885,698 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl198,766,109 - 98,885,671 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604327,061,434 - 27,186,945 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cwf19l2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247842,113,153 - 2,253,466 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cwf19l2
1527 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:299
Count of miRNA genes:242
Interacting mature miRNAs:261
Transcripts:ENSMUST00000027027
Prediction methods:Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142326Tgq19_mtriglyceride QTL 19 (mouse)Not determined121060750Mouse
1300899Chol6_mcholesterol 6 (mouse)Not determined9129902913Mouse
13434920Dcollq1_mdifferential colonization level QTL 1 (mouse)9130341840Mouse


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_027545 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006509865 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC122444 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC162921 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK014327 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK031423 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK033457 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK037905 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK045423 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK083386 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK135981 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK148862 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK167727 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC043480 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC051218 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC100536 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC125483 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC125485 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000027027   ⟹   ENSMUSP00000027027
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl93,403,592 - 3,479,236 (+)Ensembl
GRCm38.p6 Ensembl93,403,592 - 3,479,236 (+)Ensembl
RefSeq Acc Id: ENSMUST00000212101
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl93,440,563 - 3,450,486 (+)Ensembl
GRCm38.p6 Ensembl93,440,563 - 3,450,486 (+)Ensembl
RefSeq Acc Id: ENSMUST00000212128
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl93,404,088 - 3,431,942 (+)Ensembl
GRCm38.p6 Ensembl93,404,088 - 3,431,942 (+)Ensembl
RefSeq Acc Id: ENSMUST00000212644
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl93,404,088 - 3,413,199 (+)Ensembl
GRCm38.p6 Ensembl93,404,088 - 3,413,199 (+)Ensembl
RefSeq Acc Id: NM_027545   ⟹   NP_081821
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3993,404,085 - 3,479,236 (+)NCBI
GRCm3893,404,085 - 3,479,236 (+)NCBI
MGSCv3793,404,085 - 3,479,236 (+)RGD
Celera3119,215,796 - 119,285,730 (-)NCBI
cM Map9 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006509865   ⟹   XP_006509928
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3993,403,592 - 3,467,126 (+)NCBI
GRCm3893,403,592 - 3,467,126 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_081821   ⟸   NM_027545
- UniProtKB: Q8BZV5 (UniProtKB/Swiss-Prot),   Q80XN7 (UniProtKB/Swiss-Prot),   Q3UX04 (UniProtKB/Swiss-Prot),   Q3TIS8 (UniProtKB/Swiss-Prot),   Q8C0F8 (UniProtKB/Swiss-Prot),   Q8BG79 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006509928   ⟸   XM_006509865
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSMUSP00000027027   ⟸   ENSMUST00000027027

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8BG79-F1-model_v2 AlphaFold Q8BG79 1-887 view protein structure

Promoters
RGD ID:6844380
Promoter ID:MM_KWN:56285
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_027545,   UC009OAY.1,   UC009OAZ.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3693,403,731 - 3,404,231 (+)MPROMDB
RGD ID:8668716
Promoter ID:EPDNEW_M12389
Type:multiple initiation site
Name:Cwf19l2_1
Description:Mus musculus CWF19-like 2, cell cycle control , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3893,404,088 - 3,404,148EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1918023 AgrOrtholog
Ensembl Genes ENSMUSG00000025898 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000027027 ENTREZGENE
  ENSMUST00000027027.7 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.428.10 UniProtKB/Swiss-Prot
InterPro Cwf19-like UniProtKB/Swiss-Prot
  Cwf19-like_C_dom-1 UniProtKB/Swiss-Prot
  Cwf19-like_C_dom-2 UniProtKB/Swiss-Prot
  HIT-like_sf UniProtKB/Swiss-Prot
KEGG Report mmu:244672 UniProtKB/Swiss-Prot
MGD MGI:1918023 ENTREZGENE
NCBI Gene 244672 ENTREZGENE
PANTHER CWF19-LIKE PROTEIN 2 UniProtKB/Swiss-Prot
  PTHR12072 UniProtKB/Swiss-Prot
Pfam CwfJ_C_1 UniProtKB/Swiss-Prot
  CwfJ_C_2 UniProtKB/Swiss-Prot
PhenoGen Cwf19l2 PhenoGen
Superfamily-SCOP SSF54197 UniProtKB/Swiss-Prot
UniProt C19L2_MOUSE UniProtKB/Swiss-Prot
  Q3TIS8 ENTREZGENE
  Q3UX04 ENTREZGENE
  Q80XN7 ENTREZGENE
  Q8BG79 ENTREZGENE
  Q8BZV5 ENTREZGENE
  Q8C0F8 ENTREZGENE
UniProt Secondary Q3TIS8 UniProtKB/Swiss-Prot
  Q3UX04 UniProtKB/Swiss-Prot
  Q80XN7 UniProtKB/Swiss-Prot
  Q8BZV5 UniProtKB/Swiss-Prot
  Q8C0F8 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-06-27 Cwf19l2  CWF19 like cell cycle control factor 2  Cwf19l2  CWF19-like 2, cell cycle control (S. pombe)  Symbol and/or name change 5135510 APPROVED