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Gene: Sarm1 (sterile alpha and HEAT/Armadillo motif containing 1) Mus musculus
Symbol: Sarm1
Name: sterile alpha and HEAT/Armadillo motif containing 1
Description: ENCODES a protein that exhibits signaling adaptor activity (inferred); INVOLVED IN regulation of apoptotic process; regulation of dendrite morphogenesis; regulation of neuron death; ASSOCIATED WITH abnormal circulating tumor necrosis factor level; abnormal nervous system physiology; decreased apoptosis; ASSOCIATED WITH Folate Malabsorption, Hereditary (ortholog); respiratory syncytial virus infectious disease (ortholog); FOUND IN cytoplasm; dendrite; extrinsic component of mitochondrial outer membrane; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; diclofenac; ethanol
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: A830091I15Rik; C78606; MyD885; Sarm; sterile alpha and TIR motif containing 1; sterile alpha and TIR motif-containing protein 1; Tir-1 homolog
Homo sapiens (human) : SARM1 (sterile alpha and TIR motif containing 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Sarm1 (sterile alpha and TIR motif containing 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sarm1 (sterile alpha and TIR motif containing 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SARM1 (sterile alpha and TIR motif containing 1)
Canis lupus familiaris (dog) : SARM1 (sterile alpha and TIR motif containing 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sarm1 (sterile alpha and TIR motif containing 1)
Sus scrofa (pig) : SARM1 (sterile alpha and TIR motif containing 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm381178,470,273 - 78,497,816 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371178,285,832 - 78,311,256 (-)NCBIGRCm37mm9NCBIm37
MGSCv361178,289,486 - 78,313,898 (-)NCBImm8
Celera1188,104,406 - 88,129,827 (-)NCBICelera
Cytogenetic Map11 B5NCBI
cM Map1146.74NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Sarm1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1320777
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.