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Gene: NPAS1 (neuronal PAS domain protein 1) Homo sapiens
Symbol: NPAS1
Name: neuronal PAS domain protein 1
RGD ID: 1320711
Description: Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and protein heterodimerization activity. Predicted to be involved in negative regulation of transcription, DNA-templated and regulation of transcription by RNA polymerase II. Predicted to localize to nuclear chromatin.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: basic-helix-loop-helix-PAS protein MOP5; bHLHe11; class E basic helix-loop-helix protein 11; member of PAS protein 5; member of PAS superfamily 5; MOP5; neuronal PAS domain-containing protein 1; neuronal PAS1; PAS domain-containing protein 5; PASD5
Mus musculus (house mouse) : Npas1 (neuronal PAS domain protein 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Npas1 (neuronal PAS domain protein 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Npas1 (neuronal PAS domain protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : NPAS1 (neuronal PAS domain protein 1)
Canis lupus familiaris (dog) : NPAS1 (neuronal PAS domain protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Npas1 (neuronal PAS domain protein 1)
Sus scrofa (pig) : NPAS1 (neuronal PAS domain protein 1)
Chlorocebus sabaeus (African green monkey) : NPAS1 (neuronal PAS domain protein 1)
Heterocephalus glaber (naked mole-rat) : Npas1 (neuronal PAS domain protein 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl1947,019,837 - 47,045,775 (+)EnsemblGRCh38hg38GRCh38
GRCh381947,019,837 - 47,045,775 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371947,523,077 - 47,549,033 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361952,215,983 - 52,240,857 (+)NCBINCBI36hg18NCBI36
Build 341952,215,982 - 52,240,856NCBI
Celera1944,328,506 - 44,352,897 (+)NCBI
Cytogenetic Map19q13.32NCBI
HuRef1943,948,324 - 43,973,242 (+)NCBIHuRef
CHM1_11947,524,956 - 47,550,909 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on NPAS1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1320711
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.