Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | TMEM8B | Human | 3,4-methylenedioxymethamphetamine | increases expression | ISO | Tmem8b (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of TMEM8B mRNA | CTD | PMID:20188158 | TMEM8B | Human | 4,4'-sulfonyldiphenol | decreases methylation | ISO | Tmem8b (Mus musculus) | 6480464 | bisphenol S results in decreased methylation of TMEM8B exon | CTD | PMID:33297965 | TMEM8B | Human | acrylamide | decreases expression | EXP | | 6480464 | Acrylamide results in decreased expression of TMEM8B mRNA | CTD | PMID:32763439 | TMEM8B | Human | aflatoxin B1 | increases methylation | EXP | | 6480464 | Aflatoxin B1 results in increased methylation of TMEM8B gene | CTD | PMID:27153756 | TMEM8B | Human | antirheumatic drug | increases expression | EXP | | 6480464 | Antirheumatic Agents results in increased expression of TMEM8B mRNA | CTD | PMID:24449571 | TMEM8B | Human | aristolochic acid A | decreases expression | EXP | | 6480464 | aristolochic acid I results in decreased expression of TMEM8B mRNA | CTD | PMID:33212167 | TMEM8B | Human | atrazine | increases expression | EXP | | 6480464 | Atrazine results in increased expression of TMEM8B mRNA | CTD | PMID:22378314 | TMEM8B | Human | benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzo(a)pyrene results in decreased expression of TMEM8B mRNA | CTD | PMID:26238291 | TMEM8B | Human | benzo[a]pyrene | decreases methylation | EXP | | 6480464 | Benzo(a)pyrene results in decreased methylation of TMEM8B promoter | CTD | PMID:27901495 | TMEM8B | Human | bisphenol A | decreases expression | ISO | Tmem8b (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of TMEM8B mRNA | CTD | PMID:25181051 | TMEM8B | Human | bisphenol A | increases expression | ISO | Tmem8b (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of TMEM8B mRNA | CTD | PMID:30816183 | TMEM8B | Human | butanal | decreases expression | EXP | | 6480464 | butyraldehyde results in decreased expression of TMEM8B mRNA | CTD | PMID:26079696 | TMEM8B | Human | C60 fullerene | affects expression | ISO | Tmem8b (Rattus norvegicus) | 6480464 | fullerene C60 affects the expression of TMEM8B mRNA | CTD | PMID:19167457 | TMEM8B | Human | cadmium dichloride | increases expression | EXP | | 6480464 | Cadmium Chloride results in increased expression of TMEM8B mRNA | CTD | PMID:38382870 | TMEM8B | Human | cadmium dichloride | decreases expression | EXP | | 6480464 | Cadmium Chloride results in decreased expression of TMEM8B mRNA | CTD | PMID:38568856 | TMEM8B | Human | carbon nanotube | decreases expression | ISO | Tmem8b (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | TMEM8B | Human | cisplatin | increases expression | EXP | | 6480464 | Cisplatin results in increased expression of TMEM8B mRNA | CTD | PMID:27392435 | TMEM8B | Human | cisplatin | multiple interactions | EXP | | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of TMEM8B mRNA | CTD | PMID:27392435 | TMEM8B | Human | dorsomorphin | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | TMEM8B | Human | doxorubicin | decreases expression | EXP | | 6480464 | Doxorubicin results in decreased expression of TMEM8B mRNA | CTD | PMID:29803840 | TMEM8B | Human | entinostat | decreases expression | EXP | | 6480464 | entinostat results in decreased expression of TMEM8B mRNA | CTD | PMID:26272509 | TMEM8B | Human | entinostat | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of TMEM8B mRNA | CTD | PMID:27188386 | TMEM8B | Human | ethanol | increases expression | ISO | Tmem8b (Mus musculus) | 6480464 | Ethanol results in increased expression of TMEM8B mRNA | CTD | PMID:30319688 | TMEM8B | Human | maneb | multiple interactions | ISO | Tmem8b (Mus musculus) | 6480464 | [Maneb co-treated with Paraquat] results in decreased expression of TMEM8B mRNA | CTD | PMID:36117858 | TMEM8B | Human | methoxychlor | affects methylation | ISO | Tmem8b (Rattus norvegicus) | 6480464 | Methoxychlor affects the methylation of TMEM8B gene | CTD | PMID:35440735 | TMEM8B | Human | methylmercury chloride | decreases expression | EXP | | 6480464 | methylmercuric chloride results in decreased expression of TMEM8B mRNA | CTD | PMID:28001369 | TMEM8B | Human | N-ethyl-N-nitrosourea | increases mutagenesis | ISO | Tmem8b (Mus musculus) | 6480464 | Ethylnitrosourea results in increased mutagenesis of TMEM8B intron | CTD | PMID:27776689 | TMEM8B | Human | niclosamide | increases expression | EXP | | 6480464 | Niclosamide results in increased expression of TMEM8B mRNA | CTD | PMID:36318118 | TMEM8B | Human | ozone | multiple interactions | ISO | Tmem8b (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of TMEM8B mRNA | CTD | PMID:34911549 | TMEM8B | Human | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of TMEM8B mRNA | CTD | PMID:26690555 | TMEM8B | Human | paracetamol | increases expression | ISO | Tmem8b (Rattus norvegicus) | 6480464 | Acetaminophen results in increased expression of TMEM8B mRNA | CTD | PMID:33387578 | TMEM8B | Human | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of TMEM8B mRNA | CTD | PMID:25704631 | TMEM8B | Human | paraquat | multiple interactions | ISO | Tmem8b (Mus musculus) | 6480464 | [Maneb co-treated with Paraquat] results in decreased expression of TMEM8B mRNA | CTD | PMID:36117858 | TMEM8B | Human | SB 431542 | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | TMEM8B | Human | silicon dioxide | decreases expression | EXP | | 6480464 | Silicon Dioxide analog results in decreased expression of TMEM8B mRNA | CTD | PMID:25895662 | TMEM8B | Human | temozolomide | decreases expression | EXP | | 6480464 | Temozolomide results in decreased expression of TMEM8B mRNA | CTD | PMID:31758290 | TMEM8B | Human | titanium dioxide | decreases methylation | ISO | Tmem8b (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of TMEM8B gene | CTD | PMID:35295148 | TMEM8B | Human | trichostatin A | affects expression | EXP | | 6480464 | trichostatin A affects the expression of TMEM8B mRNA | CTD | PMID:28542535 | TMEM8B | Human | tris(2-butoxyethyl) phosphate | affects expression | EXP | | 6480464 | tris(2-butoxyethyl) phosphate affects the expression of TMEM8B mRNA | CTD | PMID:29024780 | TMEM8B | Human | valproic acid | affects expression | ISO | Tmem8b (Mus musculus) | 6480464 | Valproic Acid affects the expression of TMEM8B mRNA | CTD | PMID:17963808 | TMEM8B | Human | valproic acid | decreases expression | EXP | | 6480464 | Valproic Acid results in decreased expression of TMEM8B mRNA | CTD | PMID:26272509 | TMEM8B | Human | valproic acid | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of TMEM8B mRNA | CTD | PMID:27188386 | |