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Gene: SIM1 (SIM bHLH transcription factor 1) Homo sapiens
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Symbol: SIM1
Name: SIM bHLH transcription factor 1
RGD ID: 1320567
Description: Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and protein heterodimerization activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to localize to nuclear chromatin. Implicated in obesity.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: bHLHe14; class E basic helix-loop-helix protein 14; single-minded family bHLH transcription factor 1; single-minded homolog 1
Orthologs:
Mus musculus (house mouse) : Sim1 (single-minded family bHLH transcription factor 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Sim1 (SIM bHLH transcription factor 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sim1 (SIM bHLH transcription factor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SIM1 (SIM bHLH transcription factor 1)
Canis lupus familiaris (dog) : SIM1 (SIM bHLH transcription factor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sim1 (SIM bHLH transcription factor 1)
Sus scrofa (pig) : SIM1 (SIM bHLH transcription factor 1)
Chlorocebus sabaeus (African green monkey) : SIM1 (SIM bHLH transcription factor 1)
Heterocephalus glaber (naked mole-rat) : Sim1 (SIM bHLH transcription factor 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl6100,385,015 - 100,464,929 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl6100,385,009 - 100,464,921 (-)EnsemblGRCh38hg38GRCh38
GRCh386100,385,009 - 100,464,929 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh376100,832,891 - 100,912,805 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366100,943,471 - 101,018,272 (-)NCBINCBI36hg18NCBI36
Build 346100,943,470 - 101,018,272NCBI
Celera6101,480,981 - 101,555,761 (-)NCBI
Cytogenetic Map6q16.3NCBI
HuRef698,275,663 - 98,350,456 (-)NCBIHuRef
CHM1_16101,098,793 - 101,173,570 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on SIM1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1320567
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.