Lig3 (ligase III, DNA, ATP-dependent) - Rat Genome Database

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Gene: Lig3 (ligase III, DNA, ATP-dependent) Mus musculus
Analyze
Symbol: Lig3
Name: ligase III, DNA, ATP-dependent
RGD ID: 1320453
MGI Page MGI
Description: Predicted to enable DNA ligase (ATP) activity. Involved in double-strand break repair via alternative nonhomologous end joining and mitochondrion organization. Acts upstream of or within double-strand break repair via nonhomologous end joining; mitochondrial DNA repair; and negative regulation of DNA recombination. Located in synaptonemal complex. Is expressed in several structures, including early conceptus; gonad; hemolymphoid system gland; liver; and lung. Human ortholog(s) of this gene implicated in mitochondrial DNA depletion syndrome and pancreatic cancer. Orthologous to human LIG3 (DNA ligase 3).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: D11Wsu78; D11Wsu78e; DNA ligase (ATP) 3; DNA ligase 3; DNA ligase III; MGC78176; polydeoxyribonucleotide synthase [ATP] 3
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391182,671,935 - 82,695,100 (+)NCBIGRCm39mm39
GRCm39 Ensembl1182,671,934 - 82,695,100 (+)Ensembl
GRCm381182,781,109 - 82,804,274 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1182,781,108 - 82,804,274 (+)EnsemblGRCm38mm10GRCm38
MGSCv371182,594,637 - 82,617,776 (+)NCBIGRCm37mm9NCBIm37
MGSCv361182,597,330 - 82,620,469 (+)NCBImm8
Celera1192,400,612 - 92,423,646 (+)NCBICelera
Cytogenetic Map11CNCBI
cM Map1150.23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:8889548   PMID:9001252   PMID:9363683   PMID:10349636   PMID:10725249   PMID:10995569   PMID:11042159   PMID:11076861   PMID:11598119   PMID:11896201   PMID:12383505   PMID:12477932  
PMID:12520002   PMID:14610273   PMID:15033168   PMID:15782199   PMID:16141072   PMID:16141073   PMID:16648486   PMID:17967808   PMID:18784354   PMID:18799693   PMID:19633665   PMID:20300987  
PMID:20362541   PMID:20362542   PMID:21267068   PMID:21390131   PMID:21390132   PMID:21655080   PMID:21677750   PMID:21873635   PMID:22306462   PMID:22308491   PMID:22922362   PMID:23042675  
PMID:23154201   PMID:23884459   PMID:24342190   PMID:24457600   PMID:24674627   PMID:24793032   PMID:26167872   PMID:26206133   PMID:27806302   PMID:30595499   PMID:32098917   PMID:32325033  
PMID:34555355   PMID:35012549  


Genomics

Comparative Map Data
Lig3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391182,671,935 - 82,695,100 (+)NCBIGRCm39mm39
GRCm39 Ensembl1182,671,934 - 82,695,100 (+)Ensembl
GRCm381182,781,109 - 82,804,274 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1182,781,108 - 82,804,274 (+)EnsemblGRCm38mm10GRCm38
MGSCv371182,594,637 - 82,617,776 (+)NCBIGRCm37mm9NCBIm37
MGSCv361182,597,330 - 82,620,469 (+)NCBImm8
Celera1192,400,612 - 92,423,646 (+)NCBICelera
Cytogenetic Map11CNCBI
cM Map1150.23NCBI
LIG3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381734,980,512 - 35,010,872 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1734,980,512 - 35,009,743 (+)EnsemblGRCh38hg38GRCh38
GRCh371733,307,531 - 33,336,762 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361730,331,651 - 30,356,201 (+)NCBINCBI36hg18NCBI36
Build 341730,331,696 - 30,355,936NCBI
Celera1730,217,714 - 30,242,284 (+)NCBI
Cytogenetic Map17q12NCBI
HuRef1729,493,447 - 29,518,012 (+)NCBIHuRef
CHM1_11733,371,911 - 33,396,481 (+)NCBICHM1_1
T2T-CHM13v2.01735,928,427 - 35,957,659 (+)NCBI
Lig3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21067,717,796 - 67,741,141 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1067,717,812 - 67,798,414 (+)Ensembl
Rnor_6.01070,134,734 - 70,158,051 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1070,134,729 - 70,158,055 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01069,765,441 - 69,788,758 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41071,000,287 - 71,021,398 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11071,013,909 - 71,035,020 (+)NCBI
Celera1066,662,184 - 66,683,295 (+)NCBICelera
Cytogenetic Map10q26NCBI
Lig3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554819,696,054 - 9,715,637 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554819,696,050 - 9,716,154 (+)NCBIChiLan1.0ChiLan1.0
LIG3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11722,073,487 - 22,097,754 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1722,074,046 - 22,095,220 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01721,776,483 - 21,805,706 (-)NCBIMhudiblu_PPA_v0panPan3
LIG3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1938,346,275 - 38,366,634 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl938,346,199 - 38,366,193 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha937,569,261 - 37,590,027 (-)NCBI
ROS_Cfam_1.0939,158,185 - 39,178,954 (-)NCBI
ROS_Cfam_1.0 Ensembl939,155,826 - 39,178,934 (-)Ensembl
UMICH_Zoey_3.1937,940,790 - 37,961,563 (-)NCBI
UNSW_CanFamBas_1.0938,226,708 - 38,247,470 (-)NCBI
UU_Cfam_GSD_1.0938,314,196 - 38,334,891 (-)NCBI
Lig3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560237,328,228 - 37,350,583 (-)NCBI
SpeTri2.0NW_004936538206,179 - 228,487 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LIG3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1240,147,681 - 40,183,622 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11240,153,105 - 40,205,077 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21241,714,491 - 41,773,847 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LIG3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11628,487,953 - 28,511,945 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1628,490,434 - 28,511,130 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660751,476,469 - 1,500,221 (-)NCBIVero_WHO_p1.0
Lig3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248752,872,357 - 2,893,967 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046248752,871,944 - 2,907,757 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
UniSTS:236670  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381182,803,887 - 82,804,086UniSTSGRCm38
MGSCv371182,617,389 - 82,617,588UniSTSGRCm37
Celera1192,423,259 - 92,423,458UniSTS
Cytogenetic Map11B5UniSTS
cM Map1148.0UniSTS
Lig3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv371182,603,378 - 82,604,071UniSTSGRCm37
Celera1192,409,248 - 92,409,941UniSTS
Cytogenetic Map11B5UniSTS
cM Map1148.0UniSTS
RH125886  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381182,804,003 - 82,804,251UniSTSGRCm38
MGSCv371182,617,505 - 82,617,753UniSTSGRCm37
Celera1192,423,375 - 92,423,623UniSTS
Cytogenetic Map11B5UniSTS
cM Map1148.0UniSTS
Whitehead/MRC_RH111085.05UniSTS
MARC_3929-3930:996679185:1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381182,796,031 - 82,797,340UniSTSGRCm38
MGSCv371182,609,533 - 82,610,842UniSTSGRCm37
Celera1192,415,403 - 92,416,712UniSTS
Cytogenetic Map11B5UniSTS
cM Map1148.0UniSTS
D10Chm170  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381182,783,623 - 82,783,846UniSTSGRCm38
MGSCv371182,597,125 - 82,597,348UniSTSGRCm37
Celera1192,402,995 - 92,403,218UniSTS
Cytogenetic Map11B5UniSTS
cM Map1148.0UniSTS
Lig3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381182,789,876 - 82,790,569UniSTSGRCm38
MGSCv371182,603,378 - 82,604,071UniSTSGRCm37
Celera1192,409,248 - 92,409,941UniSTS
Cytogenetic Map11B5UniSTS
Lig3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11B5UniSTS
Lig3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11B5UniSTS


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1912420496897826Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112180736495881231Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113589082784890826Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113628257783481356Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114570858189818733Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115007819184078411Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115249438586494385Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115339058887390737Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115412675283733652Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156864027114157957Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115775466091754758Mouse
1300924Ity2_mimmunity to S. typhimurium 2 (mouse)Not determined15850803087695238Mouse
4141982Skts-fp2_mskin tumor susceptibility in FVB and PWK 2 (mouse)Not determined5871926685066529Mouse
1301987Pid3_mprior incubation determinant 3 (mouse)Not determined116168682088699728Mouse
1301319Dautb4_mdopamine uptake transporter binding 4 (mouse)Not determined116215600596156153Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162590826109390826Mouse
10044004Stzid3_mstreptozotocin induced diabetes susceptibility 3 (mouse)Not determined116331940794063918Mouse
11039502Ltpr6b_mLeishmania tropica response 6b (mouse)116483033698830473Mouse
11039501Ltpr6a_mLeishmania tropica response 6a (mouse)116483033698830473Mouse
11039515Ltpr6_mLeishmania tropica response 6 (mouse)116483033698830473Mouse
1357766Si5lq6_mserum IGFBP-5 level QTL 6 (mouse)Not determined1166733420100733652Mouse
1301546Pcir2_mperiosteal circumference 2 (mouse)Not determined1166733420100733652Mouse
1301833Tbbmd5_mtotal body bone mineral density 5 (mouse)Not determined1166733420100733652Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166733420100733652Mouse
4141012Femwf6_mfemur work to failure 6 (mouse)Not determined66733420100733652Mouse
1300784Prdt3_mprion disease incubation time 3 (mouse)Not determined1166733420100733652Mouse
27226783Tibl5_mtibia length 5, 5 week (mouse)1168190826101890826Mouse
1558812Rafar_mretinoic acid induced forelimb autopod reduction (mouse)Not determined1170691198104691366Mouse
1301681Sle13_msystematic lupus erythematosus susceptibility 13 (mouse)Not determined1170691198104691366Mouse
1300651Pcyts3_mplasmacytoma susceptibility 3 (mouse)Not determined1170691198104691366Mouse
4141339Nilac2_mnicotine induced locomotor activity 2 (mouse)Not determined1170691198104691366Mouse
1301404Sbmd4_mspinal bone mineral density 4 (mouse)Not determined1172019649106019734Mouse
1301078Alcp2_malcohol preference locus 2 (mouse)Not determined117220979684731462Mouse
1301310Tmevd5_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 5 (mouse)Not determined1172726125106726289Mouse
4142348Pstc2_mperiosteal circumference 2 (mouse)Not determined1172818615106818733Mouse
10043866Adip19_madiposity 19 (mouse)Not determined1172818615106818733Mouse
11038695Par8_mpulmonary adenoma resistance 8 (mouse)1177063779111063918Mouse
1301414Heal10_mwound healing/regeneration 10 (mouse)Not determined1177437183111437322Mouse
10045616Heal25_mwound healing/regeneration 25 (mouse)Not determined1177437183111437322Mouse
1302124Eae7_msusceptibility to experimental allergic encephalomyelitis 7 (mouse)Not determined117757387399377820Mouse
10413882Moe1_mmodifier of epilepsy 1 (mouse)1177770978111771099Mouse
1301640Lore4_mloss of righting induced by ethanol 4 (mouse)Not determined1179156009107616472Mouse
14746970Manh71_mmandible shape 71 (mouse)1179416257113416257Mouse
10043865T2dm5sa_mtype 2 diabetes mellitus 5 in SMXA RI mice (mouse)Not determined1179813759104502698Mouse
27226758Femd3_mfemur midshaft diameter 3, 5 week (mouse)1180890826101890826Mouse
1300649Crhq1_mcompensatory renal hypertrophy QTL 1 (mouse)Not determined1181574481115574636Mouse
1300766Skull16_mskull morphology 16 (mouse)Not determined1181574481115574636Mouse
10412288Carg4_mCandida albicans resistance gene 4 (mouse)Not determined1181810267115810267Mouse
1301072Eae22_mexperimental allergic encephalomyelitis 22 (mouse)Not determined1182377698116377820Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:4955
Count of miRNA genes:872
Interacting mature miRNAs:1174
Transcripts:ENSMUST00000021039, ENSMUST00000080461, ENSMUST00000092849, ENSMUST00000131537, ENSMUST00000154887, ENSMUST00000155818, ENSMUST00000172609, ENSMUST00000172837, ENSMUST00000173009, ENSMUST00000173347, ENSMUST00000173722, ENSMUST00000173727
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001291245 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001291246 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001291247 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001403856 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001403857 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001403858 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001403859 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001403860 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001403861 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001403862 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001403863 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001403864 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001403865 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_010716 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006532347 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006532348 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006532350 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006532353 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004936802 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AI840566 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK010719 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK031540 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK143531 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK150644 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK156018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK156030 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK156825 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK167363 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK169648 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK177937 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK181064 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK186211 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK188257 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK213067 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL645594 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC026143 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC049240 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY241147 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY307824 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD351365 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CF198126 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466556 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U66057 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U66058 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  W83057 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000021039   ⟹   ENSMUSP00000021039
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1182,671,961 - 82,695,100 (+)Ensembl
GRCm38.p6 Ensembl1182,781,135 - 82,804,274 (+)Ensembl
RefSeq Acc Id: ENSMUST00000080461   ⟹   ENSMUSP00000079317
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1182,672,011 - 82,691,479 (+)Ensembl
GRCm38.p6 Ensembl1182,781,185 - 82,800,653 (+)Ensembl
RefSeq Acc Id: ENSMUST00000092849   ⟹   ENSMUSP00000090525
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1182,671,934 - 82,693,688 (+)Ensembl
GRCm38.p6 Ensembl1182,781,108 - 82,802,862 (+)Ensembl
RefSeq Acc Id: ENSMUST00000131537   ⟹   ENSMUSP00000133672
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1182,672,024 - 82,681,131 (+)Ensembl
GRCm38.p6 Ensembl1182,781,198 - 82,790,305 (+)Ensembl
RefSeq Acc Id: ENSMUST00000154887
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1182,688,044 - 82,690,393 (+)Ensembl
GRCm38.p6 Ensembl1182,797,218 - 82,799,567 (+)Ensembl
RefSeq Acc Id: ENSMUST00000155818
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1182,686,511 - 82,690,376 (+)Ensembl
GRCm38.p6 Ensembl1182,795,685 - 82,799,550 (+)Ensembl
RefSeq Acc Id: ENSMUST00000172609
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1182,671,968 - 82,687,367 (+)Ensembl
GRCm38.p6 Ensembl1182,781,142 - 82,796,541 (+)Ensembl
RefSeq Acc Id: ENSMUST00000172837   ⟹   ENSMUSP00000134101
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1182,689,175 - 82,695,100 (+)Ensembl
GRCm38.p6 Ensembl1182,798,349 - 82,804,274 (+)Ensembl
RefSeq Acc Id: ENSMUST00000173009   ⟹   ENSMUSP00000133348
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1182,672,024 - 82,681,130 (+)Ensembl
GRCm38.p6 Ensembl1182,781,198 - 82,790,304 (+)Ensembl
RefSeq Acc Id: ENSMUST00000173347   ⟹   ENSMUSP00000134300
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1182,672,019 - 82,692,851 (+)Ensembl
GRCm38.p6 Ensembl1182,781,193 - 82,802,025 (+)Ensembl
RefSeq Acc Id: ENSMUST00000173722   ⟹   ENSMUSP00000133805
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1182,672,029 - 82,695,024 (+)Ensembl
GRCm38.p6 Ensembl1182,781,203 - 82,804,198 (+)Ensembl
RefSeq Acc Id: ENSMUST00000173727   ⟹   ENSMUSP00000133849
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1182,672,019 - 82,692,852 (+)Ensembl
GRCm38.p6 Ensembl1182,781,193 - 82,802,026 (+)Ensembl
RefSeq Acc Id: NM_001291245   ⟹   NP_001278174
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391182,671,935 - 82,695,100 (+)NCBI
GRCm381182,781,109 - 82,804,274 (+)NCBI
Celera1192,400,586 - 92,423,646 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001291246   ⟹   NP_001278175
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391182,671,935 - 82,695,100 (+)NCBI
GRCm381182,781,109 - 82,804,274 (+)NCBI
Celera1192,400,586 - 92,423,646 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001291247   ⟹   NP_001278176
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391182,671,935 - 82,695,100 (+)NCBI
GRCm381182,781,109 - 82,804,274 (+)NCBI
Celera1192,400,586 - 92,423,646 (+)NCBI
Sequence:
RefSeq Acc Id: NM_010716   ⟹   NP_034846
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391182,671,935 - 82,695,100 (+)NCBI
GRCm381182,781,109 - 82,804,274 (+)NCBI
MGSCv371182,594,637 - 82,617,776 (+)RGD
Celera1192,400,586 - 92,423,646 (+)NCBI
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006532347   ⟹   XP_006532410
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391182,672,226 - 82,695,100 (+)NCBI
GRCm381182,781,397 - 82,802,026 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006532348   ⟹   XP_006532411
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391182,672,264 - 82,695,100 (+)NCBI
GRCm381182,781,396 - 82,802,015 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006532350   ⟹   XP_006532413
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391182,672,240 - 82,695,100 (+)NCBI
GRCm381182,781,414 - 82,802,972 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006532353   ⟹   XP_006532416
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391182,672,226 - 82,691,481 (+)NCBI
GRCm381182,781,424 - 82,800,655 (+)NCBI
Sequence:
RefSeq Acc Id: XR_004936802
RefSeq Status:
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391182,672,226 - 82,695,100 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001278174 (Get FASTA)   NCBI Sequence Viewer  
  NP_001278175 (Get FASTA)   NCBI Sequence Viewer  
  NP_001278176 (Get FASTA)   NCBI Sequence Viewer  
  NP_001390785 (Get FASTA)   NCBI Sequence Viewer  
  NP_001390786 (Get FASTA)   NCBI Sequence Viewer  
  NP_001390787 (Get FASTA)   NCBI Sequence Viewer  
  NP_001390788 (Get FASTA)   NCBI Sequence Viewer  
  NP_001390789 (Get FASTA)   NCBI Sequence Viewer  
  NP_001390790 (Get FASTA)   NCBI Sequence Viewer  
  NP_001390791 (Get FASTA)   NCBI Sequence Viewer  
  NP_001390792 (Get FASTA)   NCBI Sequence Viewer  
  NP_001390793 (Get FASTA)   NCBI Sequence Viewer  
  NP_001390794 (Get FASTA)   NCBI Sequence Viewer  
  NP_034846 (Get FASTA)   NCBI Sequence Viewer  
  XP_006532410 (Get FASTA)   NCBI Sequence Viewer  
  XP_006532411 (Get FASTA)   NCBI Sequence Viewer  
  XP_006532413 (Get FASTA)   NCBI Sequence Viewer  
  XP_006532416 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC53003 (Get FASTA)   NCBI Sequence Viewer  
  AAC53004 (Get FASTA)   NCBI Sequence Viewer  
  AAH49240 (Get FASTA)   NCBI Sequence Viewer  
  BAE25421 (Get FASTA)   NCBI Sequence Viewer  
  BAE29732 (Get FASTA)   NCBI Sequence Viewer  
  BAE33548 (Get FASTA)   NCBI Sequence Viewer  
  BAE33553 (Get FASTA)   NCBI Sequence Viewer  
  BAE33868 (Get FASTA)   NCBI Sequence Viewer  
  BAE39460 (Get FASTA)   NCBI Sequence Viewer  
  EDL15669 (Get FASTA)   NCBI Sequence Viewer  
  EDL15670 (Get FASTA)   NCBI Sequence Viewer  
  P97386 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_034846   ⟸   NM_010716
- Peptide Label: isoform a
- UniProtKB: Q80ZH7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006532416   ⟸   XM_006532353
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006532411   ⟸   XM_006532348
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006532410   ⟸   XM_006532347
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006532413   ⟸   XM_006532350
- Peptide Label: isoform X4
- UniProtKB: Q80ZH7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001278176   ⟸   NM_001291247
- Peptide Label: isoform b
- UniProtKB: Q3UC82 (UniProtKB/TrEMBL),   Q80ZH7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001278174   ⟸   NM_001291245
- Peptide Label: isoform a
- UniProtKB: Q80ZH7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001278175   ⟸   NM_001291246
- Peptide Label: isoform b
- UniProtKB: Q3UC82 (UniProtKB/TrEMBL),   Q80ZH7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000134101   ⟸   ENSMUST00000172837
RefSeq Acc Id: ENSMUSP00000090525   ⟸   ENSMUST00000092849
RefSeq Acc Id: ENSMUSP00000133672   ⟸   ENSMUST00000131537
RefSeq Acc Id: ENSMUSP00000134300   ⟸   ENSMUST00000173347
RefSeq Acc Id: ENSMUSP00000133348   ⟸   ENSMUST00000173009
RefSeq Acc Id: ENSMUSP00000133805   ⟸   ENSMUST00000173722
RefSeq Acc Id: ENSMUSP00000133849   ⟸   ENSMUST00000173727
RefSeq Acc Id: ENSMUSP00000021039   ⟸   ENSMUST00000021039
RefSeq Acc Id: ENSMUSP00000079317   ⟸   ENSMUST00000080461
Protein Domains
BRCT   DNA_LIGASE_A3   LIG3_BRCT   PARP-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P97386-F1-model_v2 AlphaFold P97386 1-1015 view protein structure

Promoters
RGD ID:6821186
Promoter ID:MM_KWN:8846
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000021039,   ENSMUST00000080461,   ENSMUST00000108174,   OTTMUST00000001761,   OTTMUST00000001762,   OTTMUST00000001816,   UC007KMZ.1,   UC007KNB.1,   UC007KNC.1,   UC007KND.1,   UC007KNE.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361182,593,791 - 82,595,172 (+)MPROMDB
RGD ID:6821178
Promoter ID:MM_KWN:8848
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:OTTMUST00000001819,   OTTMUST00000001820,   UC007KNG.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361182,608,521 - 82,609,021 (+)MPROMDB
RGD ID:8675842
Promoter ID:EPDNEW_M15951
Type:initiation region
Name:Lig3_1
Description:Mus musculus ligase III, DNA, ATP-dependent , transcript variant3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381182,781,151 - 82,781,211EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:109152 AgrOrtholog
Ensembl Genes ENSMUSG00000020697 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000021039 UniProtKB/TrEMBL
  ENSMUSP00000079317 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000090525 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000133348 UniProtKB/TrEMBL
  ENSMUSP00000133672 UniProtKB/TrEMBL
  ENSMUSP00000133805 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000133849 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000134101 UniProtKB/TrEMBL
  ENSMUSP00000134300 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000021039 UniProtKB/TrEMBL
  ENSMUST00000080461 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000092849 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000131537 UniProtKB/TrEMBL
  ENSMUST00000172837 UniProtKB/TrEMBL
  ENSMUST00000173009 UniProtKB/TrEMBL
  ENSMUST00000173347 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000173722 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000173727 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 1.10.3260.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.1740.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.10190 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro BRCT_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BRCT_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNA_ligase_ATP-dep UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNA_ligase_ATP-dep_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNA_ligase_ATP-dep_cent UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNA_ligase_ATP-dep_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNA_ligase_ATP-dep_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNA_ligase_N_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LIG3_BRCT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NA-bd_OB-fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_PARP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_PARP_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:16882 UniProtKB/TrEMBL
MGD MGI:109152 ENTREZGENE
NCBI Gene 16882 ENTREZGENE
Pfam DNA_ligase_A_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNA_ligase_A_M UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNA_ligase_A_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LIG3_BRCT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  zf-PARP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Lig3 PhenoGen
PROSITE BRCT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNA_LIGASE_A1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNA_LIGASE_A2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNA_LIGASE_A3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PARP_ZN_FINGER_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PARP_ZN_FINGER_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART BRCT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  zf-PARP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF117018 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF50249 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF52113 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGRFAMs dnl1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt B1AT03_MOUSE UniProtKB/TrEMBL
  DNLI3_MOUSE UniProtKB/Swiss-Prot
  G3UYI8_MOUSE UniProtKB/TrEMBL
  K4DI59_MOUSE UniProtKB/TrEMBL
  P97386 ENTREZGENE
  Q3TJN5_MOUSE UniProtKB/TrEMBL
  Q3U0I5_MOUSE UniProtKB/TrEMBL
  Q3U1F0_MOUSE UniProtKB/TrEMBL
  Q3UC82 ENTREZGENE, UniProtKB/TrEMBL
  Q80ZH7 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary E9QL81 UniProtKB/Swiss-Prot
  P97385 UniProtKB/Swiss-Prot