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Gene: WDR4 (WD repeat domain 4) Homo sapiens
Symbol: WDR4
Name: WD repeat domain 4
Description: Contributes to tRNA (guanine-N7-)-methyltransferase activity. Involved in tRNA modification. Localizes to cytosol; nucleoplasm; and tRNA methyltransferase complex. Implicated in Galloway-Mowat syndrome.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: GAMOS6; hWH; MIGSB; TRM82; TRM82 tRNA methyltransferase 82 homolog; TRMT82; tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; tRNA (guanine-N(7)-)-methyltransferase subunit WDR4; WD repeat-containing protein 4
Mus musculus (house mouse) : Wdr4 (WD repeat domain 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Wdr4 (WD repeat domain 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Wdr4 (WD repeat domain 4)
Pan paniscus (bonobo/pygmy chimpanzee) : WDR4 (WD repeat domain 4)
Canis lupus familiaris (dog) : WDR4 (WD repeat domain 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Wdr4 (WD repeat domain 4)
Sus scrofa (pig) : WDR4 (WD repeat domain 4)
Chlorocebus sabaeus (African green monkey) : WDR4 (WD repeat domain 4)
Heterocephalus glaber (naked mole-rat) : Wdr4 (WD repeat domain 4)
more info ...
Related Pseudogenes: WDR4P1   WDR4P2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl2142,843,094 - 42,879,568 (-)EnsemblGRCh38hg38GRCh38
GRCh382142,843,075 - 42,891,695 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372144,263,190 - 44,299,699 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362143,136,273 - 43,172,747 (-)NCBINCBI36hg18NCBI36
Build 342143,136,274 - 43,172,747NCBI
Celera2129,412,800 - 29,449,250 (-)NCBI
Cytogenetic Map21q22.3NCBI
HuRef2129,678,871 - 29,715,344 (-)NCBIHuRef
CHM1_12143,824,052 - 43,860,555 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on WDR4
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1320425
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.